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Tablet compression machine makes the tablets by pressing thegranules in die with lower and upper punch.

Ankur Choudhary| Equipment| Production| PrintBe the frst to comment!

Tablets are being ormed by compressing the granules using the

compression machines i"erent inno#ations to tablet

compression machines are being done to impro#e the production

rates and no$ it is possible to produce more than %&&'&&& tablets

per hour A tablet ormation takes place by the combined pressing

action o t$o punches and a die

Principle of Tablet Compression Machine:

The basic principle behind the tablet compression machine is

hydraulic pressure This pressure is transmitted unreduced

through the static (uid Any e)ternally applied pressure istransmitted #ia static (uid to all the directions in same proportion

*t also makes it possible to multiply the orce as needed

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Dierent Stages of Compression Process:

The tablet compression procedure that is used in di"erent

pharmaceutical companies is di#ided into our distinct stages

These are named as flling' metering' compression and e+ection

These all our steps are e)plained belo$,

1. Filling:This procedure o the tablet compression machine

in#ol#es transer o the granules into position or tablet

compression The ultimate product is then blended or

homogeneous blend Then the mi)ture (o$s to thecompressing

toolpunch-die ca#ity The punch-die ca#ity is made o punch-die

and lo$er punch Then the position o lo$er punch in the die isresponsible or the #olume o the ca#ity This #olume must be

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appropriately ad+usted or $eight o granules to be compressed to

make the tablets

2. Metering:The metering procedure or the tablet compression

procedure in#ol#es remo#al o e)cess granules rom the

compression machine At this stage the required $eight .#olume/

o granules to be compressed into tablets is controlled by the

height o the lo$er punch in the die and the height o the lo$er

punch is controlled by the metering cam The lo$er punch is

raised to the required le#el in the die to get the required $eight o

granules in the punch-die ca#ity The e)cess granules are scraped

rom the surace o the die table The metering method is similar

to the process used to determine the $eight o (our during the

making o a cake

3. Compression:uring compression stage the top and bottom

punches come together by pressure $ithin the die to orm the

tablet As the punches enter into the compression stage' the top

and bottom punches mo#e bet$een t$o large $heels called

compression rolls These compression rolls push the punches to

$ords the die to orm the product 0o' distance bet$een the top

and bottom punches determines the thickness and the hardness

o the tablets 1hen the punches are so close together' a thin and

hard tablet is created Today A1C .auto $eight control/ machine

is used or better result

4. !ection:The e+ection procedure or the tablet

compressionprocess in#ol#es remo#al o the tablet rom the

lo$er punch-die station *n this stage' the upper punch retracts

rom the die ca#ity and rises abo#e the turret table Then the

lo$er punch rises in the die' $hich in turn pushes the tablet

up$ard to the top surace o the die table and out o the die

ca#ity Then by a scrapper tablets are collected in the container

There are di"erent types o compression machines are a#ailable

or tablet manuacturing and these ha#e their identifcation on the

basis o the number o tablet compression stations as 2% station'

3% stations' %% stations etc

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