table 1. curriculum for biomedical science program curriculu… · table 1. curriculum for...

Table 1. Curriculum for Biomedical Science Program

a. COMMON TO ALL OPTIONS Mode of delivery (hours per

week)

Semester 1 Lecture Lab Tutorial

BLG 143 Biology I 3.0 1.5

CHY 103 General Chemistry I 3.0

MTH 131 Modern Mathematics I 4.0 1.0

PCS 120 Physics I 3.0 1.0 1.0

Liberal Table A 3.0

SCI 180 Orientation 1.0


BLG 144 Biology II 3.0 1.5

CHY 113 General Chemistry II 3.0 3.0

PCS 130 Physics II 3.0 1.0 1.0

Elective Open Elective 3.0 *

PSY 102 Intro to Psychology I 3.0


BLG 151 Microbiology I 3.0 3.0

BLG 311 Cell Biology 3.0 1.5

CHY 142 Organic Chemistry I 3.0 3.0

MTH 380 Statistics I 3.0 1.0


BMS 280 BMS Orientation II 1.0


BCH 261 Biochemistry 3.0 3.0

BLG 400 Genetics 3.0 1.0

BLG 411 Cell biology II 3.0

BLG 600 Physiology 3.0

Liberal Table A 3.0

b. REGULAR PROGRAM

Mode of delivery (hours per

week)


BCH 361 Advanced Biochemistry I 3.0 3.0

BLG 307 Molecular Biology 3.0

BLG 856 Immunology 3.0 1.5


Liberal Table A 3.0


BMS 650 Experimental Design 3.0 2.0

BLG 888 Molecular Biology Lab 3.0 1.0

Elective Table X 3.0 *


Liberal Table B 3.0


BMS 750 Systems Biology 3.0 1.5

BMS 760 Critical Thinking in BMS 3.0 2.0



Liberal Table B 3.0


BLG 850 Cancer Biology 3.0 1.5

BMS 860 Stem Cell Biology 3.0



Liberal Table B 3.0

c. CO-OPERATIVE EDUCATION

PROGRAM**

Mode of delivery (hours per

week)

Co-operative Semester (Spring/Summer) Lecture Lab Tutorial

WKT 405 Work Term I 1.0


BCH 361 Advanced Biochemistry I 3.0 3.0

BLG 307 Molecular Biology 3.0

BLG 856 Immunology 3.0 1.5


Liberal Table A 3.0

Co-operative Semester (Winter) Lecture Lab Tutorial

WKT 505 Work Term II 1.0


WKT 506 Work Term III 1.0

Co-operative Semester (Fall) Lecture Lab Tutorial

WKT 605 Work Term IV 1.0


BMS 650 Experimental Design 3.0 2.0

BLG 888 Molecular Biology Lab 3.0 1.0



Liberal Table B 3.0


WKT 606 Work Term V 1.0


BMS 750 Systems Biology 3.0 1.5

BMS 760 Critical Thinking in BMS 3.0 2.0



Liberal Table B 3.0


BMS 850 Cancer Biology 3.0 1.5

BMS 860 Stem Cell Biology 3.0



Liberal Table B 3.0

1Course will run concurrently with SCI 180

*Some courses may have additional laboratory hours

**All WKT courses graded on Pass/Fail basis. Students enter Co-op Program after Semester 4 and must

successfully complete at least four work terms to graduate from the Co-op Program. Admission requires

a minimum GPA, normally 2.67.

Table X: Electives. Students must select three (3) courses from the list.

BMS 40A/B* Project-Thesis

BMS 607 Molecular Genetics and Epigenetics

BMS 857 Advanced Immunology

BCH 461 Biochemistry of Disease

BMS 451 Medical Microbiology

BMS 605 Advanced Physiology

BMS 858 Infection and Immunity

BMS 500 Human Genetics

BMS 770 Medical Epidemiology

BMS 865 Model organisms

BMS 870 Neurobiology

BCH 362 Advanced Biochemistry II

BCH 501 Protein Biochemistry and Proteomics

BCH 580 Cell Signalling

BLG 251 Microbiology II

BLG 408 Viruses

BLG 409 Biometry

BLG 578 Pharmacology

BLG 678 Current Topics in Biology

BLG 700 Anatomy

BLG 702 Genomics and its Applications

BLG 785 Developmental Biology

BLG 788 Current Topics in Biotechnology

BLG 800 Genomics and Proteomics

BME 501/ CPS 501 Bioinformatics

MTH 231 Modern Mathematics II

CHY 242 Organic Chemistry II

CHY 436 Pharmaceutical Chemistry

PCS 229 Introduction to Medical Physics

PCS 227 Biophysics

PCS 230 Photonics and Optical Devices

PCS 300 Modern Physics

PCS 352 Nuclear Physics/Radiation Protection

PCS 354 Radiation Biology

PCS XX1 Cellular Biophysics

PCS XX2 Nanophysics

PSY 202 Introduction to Psychology II

PSY 214 Psychopharmacology

PSY 215 Psychology of Addictions

PSY 324 Biological Psychology

PSY 325 Psychological Disorders

4.0 APPENDICES

Appendix A1: Calendar Course Descriptions

Required courses for FIRST SEMESTER

There are four required courses plus students may choose either PSY 102 or one liberal course from Table

A. A program specific orientation course will also be required.

BLG143 Biology 1

This course includes the structure and function of macromolecules and the cell. Topics include cell

physiology, enzymes, membrane function, metabolism, photosynthesis and cell division. Also included is

an introduction to genetics and patterns of inheritance, evolution and diversity. Laboratory exercises

complement lectures. Lect: 3 hrs./Lab: 1.5 hrs. Course Weight: 1.00 Billing Units: 1

CHY103 General Chemistry

Atomic structure, stoichiometry, gases, chemical equilibrium, acids and bases, aqueous equilibria,

thermochemistry, energy. Lect: 3 hrs. Course Weight: 1.00 Billing Units: 1

MTH 131 Modern Mathematics 1

Limits and continuity. Differentiation with applications. Newton-Raphson method. Integration; the

Fundamental Theorem of Calculus. Linear Algebra: Systems of linear equations, Gauss elimination,

matrices. 2x2 determinants. Lect: 4 hrs./Lab: 1 hr. Course Weight: 1.00 Billing Units: 1

PCS 120 Physics I

A calculus based course covering fundamental physics concepts: units, vectors, linear motion, circular

motion, force and motion, work and energy, collisions, gravitation, electrostatics, capacitance, and simple

DC circuits. Tut: 1 hr./Lect: 3 hrs./Lab: 1 hr. Course Weight: 1.00 Billing Units: 1

PSY102 Introduction to Psychology 1

This course introduces students to psychology, the scientific study of behaviour and cognition, by

examining the basic principles of psychology and their applications to everyday experience. The course

surveys some core areas of psychology including research methods, biological bases of behaviour,

sensation and perception, memory, and cognition. Lect: 3 hrs. Antirequisites: PSY 11, PSY 105 Course

Weight: 1.00 Billing Units: 1

SCI 180 Orientation

This course focuses on topics designed to improve the effectiveness of learning strategies and study skills.

This course includes discussions on topics such as effective communication skills, learning styles, theory

of learning and successful problem solving, career planning, the Co-op program, effective use of the

library and other topics that will help students to become more resourceful and successful in their

program. All students in Science programs must enroll in SCI 180 in their first semester of studies. Lect:

1 hr. Course Weight: 1.00 Billing Units: 1

http://www.ryerson.ca/calendar/2011-2012/pg2795.html#242096


Required courses for SECOND SEMESTER

There are three required courses plus students may choose either PSY 102 or one liberal course from

Table A (which ever was not taken in semester 1). Students are also required to choose one elective

course. Students interested in pursuing a career in Medicine or other health related professions are advised

to take BLG 700 Anatomy.

BLG144 Biology II

The topics covered in this course include physiology of both plants and animals, ecological principles and

environmental issues. Laboratory exercises complement lectures. Lect: 3 hrs./Lab: 1.5 hrs. Prerequisite:

BLG 143 Course Weight: 1.00

CHY 113 General Chemistry II

Electrochemistry, atomic theory, bonding, liquids and solids. Solutions, representative elements,

transition metals, nuclear chemistry. Lect: 3 hrs./Lab: 3 hrs. Prerequisite: CHY 103 Course Weight: 1.00

Billing Units: 1

PCS 130 Physics II

A continuation of Physics I, calculus-based course. An introduction to oscillations, mechanical waves,

magnetism, electromagnetism, optics and nuclear physics. The laboratory is an essential and autonomous

part of the course. Tut: 1 hr./Lect: 4 hrs./Lab: 1 hr. Prerequisite: PCS 120, Antirequisite: SCI 104 Course


PSY 102 Introduction to Psychology I

This course introduces students to psychology, the scientific study of behaviour and cognition, by

examining the basic principles of psychology and their applications to everyday experience. The course

surveys some core areas of psychology including research methods, biological bases of behaviour,

sensation and perception, memory, and cognition. Lect: 3 hrs. Antirequisites: PSY 11, PSY 105 Course


Required courses for THIRD SEMESTER

There are four required courses plus students must choose one elective course from Table X.

BLG 151 Microbiology

This course introduces the student to the principles of microbiology. Topics include the history of

microbiology, a survey of the different types of microorganisms, prokaryotic cell structure and function,

microbial nutrition and growth, control of microorganisms, and microbial metabolism and genetics. An

introduction to taxonomy in the microbial world will also be presented. The laboratory exercises

complement the lectures and introduce the student to basic microbiological techniques and applications.

Lect: 3 hrs./Lab: 3 hrs. Prerequisite: BLG 143 and BLG 144 Course Weight: 1.00 Billing Units: 1

BLG 311 Cell Biology

This course will examine key concepts of cell structure and function. This includes membrane structure

and function, membrane transport mechanisms of small molecules and ions, cytoplasmic organization,








intracellular targeting and sorting of proteins, membrane trafficking, the cytoskeleton and nuclear

organization. We will also examine various methods used to visualize and study cell structure and

function. The laboratory component will complement basic cell structure concepts. Lect: 3 hrs./Lab: 1.5

hrs. Prerequisite: BLG 143 and BLG 144 Course Weight: 1.00 Billing Units: 1

CHY 142 Organic Chemistry 1

This is an introductory course based on the mechanistic approach to the study of organic reactions, and

includes functionality, IUPAC nomenclature, structural and steroisomerism, oxidation and reduction,

nucleophilic additions, nucleophilic substitutions, eliminations, electrophilic additions of aliphatic

compounds. The laboratory introduces techniques such as melting point, recrystallization, extraction, and

distillation. Also included are the synthesis, isolation and purification of organic compounds. Lect: 3

hrs./Lab: 3 hrs. Prerequisite: CHY 103 and CHY 113

Course Weight: 1.00 Billing Units: 1

MTH 380 Probability and Statistics I

Probability and Statistics I: Descriptive statistics. Probability (Laws of probability. Conditional

probability. Discrete probability distributions (binomial, hypergeometric, Poisson). Continuous

probability distributions, Normal, t-exponential, x². Applications of discrete and continuous distributions.

Sampling distributions (sample mean, sample proportion, difference between two samples, difference

between two sample proportions). Sampling distribution concerning mean variance and proportion for

one or two populations. Estimation for large and small samples. Hypothesis testing concerning mean,

variance and proportion for one or two populations, (large samples and small samples) including paired

data testing. Lect: 3 hrs./Lab: 1 hr. Course Weight: 1.00 Billing Units: 1

BMS 280 BMS Orientation II

This course focuses on topics designed to introduce the careers paths available to graduates of the

program. It will also review requirements needed to enter many professional schools and opportunnites

available in non traditional areas. The lectures will be complemented with speakers who will speak about

their educational path and how they arrived at their career. All students in Biomedical Sciences students

must enroll in BMS 280 in their third semester of studies. Lect: 1 hr. Course Weight: 1.00 Billing Units:

1

Required courses for FOURTH SEMESTER

There are four required courses plus students must choose one Liberal course from Table A.

BCH 261 Biochemistry

This course deals with the structure, function and chemistry of the molecular building blocks of the cell.

This includes a discussion of water and its properties, amino acids, proteins, nucleotides and nucleic

acids, carbohydrates and lipids. Also included is an introduction to enzyme function and kinetics. The

laboratory provides an introduction to the basic biochemical techniques including chromatography,

electrophoresis and spectrophotometry. (Formerly CHY 261). Lect: 3 hrs./Lab: 3 hrs. Prerequisite: BLG

143, BLG 144, CHY 142 Course Weight: 1.00 Billing Units: 1






BLG 400 Genetics

Structure, function and transmission of genes; chromosomal basis of inheritance; mono- and dihybrid

crosses; sequential steps in gene function; linkage maps; sex chromosome inheritance, cytogenetics,

genetic traits and inheritance as they relate to health care issues. Topics include normal and pathological

cytology; the human genome project; gene mapping; linkage and therapy. Tut: 1 hr./Lect: 3 hrs.

Prerequisites: BLG 143 and BLG 144 Course Weight: 1.00 Billing Units: 1

BLG 411 Cell Biology II

This course will focus on cell function and behaviour. The course will cover mechanisms of cell-cell

adhesion and cell adhesion to the extracellular matrix, mechanisms of cellular communication and signal

transduction, cell motility and morphology, regulation of the cell cycle, apoptosis and an introduction to

cell differentiation. Lect: 3 hrs. Prerequisites: BLG 311 Course Weight: 1.00 Billing Units: 1

BLG 600 Physiology

A systematic approach to the function of the main physiological systems and their integration and

interaction in the human body. Functions of the integumentary, immune, circulatory, skeletal, muscular,

respiratory, nervous, endocrine, gastrointestinal, urinary and reproductive systems. The physiological

consequences of disease, aging, exercise, and pregnancy are also considered. Lect: 3 hrs. Prerequisites:

BLG 143 and (BLG 144 or CEN 100), and BLG 311 Course Weight: 1.00 Billing Units: 1

Required courses for FIFTH SEMESTER

There are three required courses plus students must choose one elective course from Table X and one

liberal elective from Table A.

BCH 361 Advanced Biochemistry I

A course in the principles of enzymology, bioenergetics and carbohydrate metabolism. Enzymology

topics include the structure, function and regulation of enzymes and Michaelis-Menten kinetics. The

fundamentals of bioenergetics and intermediary metabolism are discussed in the context of the integration

and control of catabolism and anabolism. The course concludes with a detailed examination of

carbohydrate chemistry with emphasis on the chemical logic and the regulation of these pathways. The

laboratory introduces students to more advanced biochemical techniques. Topics include the isolation and

characterization of polysaccharides and the kinetic analysis of enzymes. (Formerly CHY 361). Lect: 3

hrs./Lab: 3 hrs. Prerequisite: CHY 261 or BCH 261 Course Weight: 1.00 Billing Units: 1

BLG 307 Molecular Biology

This course emphasizes the fundamentals of molecular biology including gene structure and function,

regulation of transcription and translation, gene expression in both prokaryotes and eukaryotes, and

recombinant DNA technology including DNA mutagenesis, protein engineering and monoclonal antibody

technology. Lect: 3 hrs.

Prerequisite: BLG 151 and (CHY 261 or BCH 261) Course Weight: 1.00 Billing Units: 1

BLG 856 Immunology

The organization and structure of the immune system including an introduction to humoral cellular

immunity and immunological techniques. The molecular and cellular basis of immunity, including










histocompatibility antigens and the basis of autoimmune diseases will also be covered. The laboratory

will complement the lectures and introduce the student to immunology reaction assays. Lect: 3 hrs/ Lab:

1.5 hours, Prerequisites: BLG 311 and (CHY 261 or BCH 261) Course Weight: 1.00 Billing Units: 1

Required courses for SIXTH SEMESTER

There are two required courses plus students must choose two Elective courses from Table X and one


BMS 650 Experimental Design (NEW COURSE)

This course will be an advanced discussion of tools and techniques that form the basis for research

discovery in genetics, biochemistry and molecular cell biology. Emphasis will be placed in key elements

of experimental design including the importance of positive and negative controls, statistical analysis,

experimental complementation and understanding experimental limitations. A discussion of bioethical

considerations in experimental design will also be included. Lecture: 3 hours/week, Tutorial: 2

hours/week. Prerequisite: BCH 261, BLG 400, BLG 307, BLG 411, Course Weight: 1.00 Billing Units: 1

BLG 888 Molecular Biology Laboratory

This lab course will cover experiments on recombinant DNA technology. The lab experience includes

experiments for DNA isolation, cloning, and restriction endonuclease digestion. Genotypic

characterization will also be investigated using PCR methodology. Protein characterization will include

isolation, SDS-polyacrylamide gel electrophoresis, and detection using Western blot analysis with

monoclonal antibodies.

Lab: 3 hrs; Tutorial: 1 h Prerequisite: BLG 307 Course Weight: 1.00 Billing Units: 1

Required courses for SEVENTH SEMESTER

There are two required courses plus students must choose two elective courses from Table X and one

liberal elective from Table B.

BMS 750 Systems Biology (NEW COURSE)

This course focuses the integration of complex biological data sets and non-reductionist approaches to

studying living organisms. This course will begin by an examination of systems theory, stochasticity in

biological systems, emergent behaviors, the advent of high-throughput biological experimental techniques

and the use of modeling to understand biological processes. The course will also examine epigenetic

systems, lipidomics, metabolomics, synthetic biology, integrative cellular signaling networks and

computational modeling of cellular systems. The laboratories will complement the lectures. Lecture: 3

hours/Lab: 1.5 hours /week Prerequisites: BLG 411 and BLG 307. Course Weight: 1.00 Billing Units: 1

BMS 760 Critical Thinking in Biomedical Sciences. (NEW COURSE)

The lecture component will emphasize the development and application of strategies and tools to analyse,

interpret and critically evaluate knowledge in biomedical sciences through the use of primary literature.

Students will learn to recognize outstanding questions, speculative arguments, ambiguities and/or flaws,

and logically suggest the use of strategies that might resolve identified issues. The course will also focus

on the ability to communicate in written and oral form. Finally, students will learn about and implement




bioethical considerations in their arguments. The tutorial component will help students learn to execute

critical thinking and communication concepts.

Lecture 3 hours/week, Tutorial 2 hours/week. Prerequisite: BMS 650 Experimental Design. Course


Required courses for EIGHTH SEMESTER

There are two required courses plus the student must choose two elective courses from Table X and one


BMS 850 Cancer Biology (NEW COURSE)

Molecular aspects of cell cycle regulation in eukaryotic cells from yeast to humans will be covered. This

knowledge will be then integrated with current concepts and knowledge about cancer in order to explore

the cellular and molecular mechanisms underlying cancer development and progression. Specific topics

covered will include the eukaryotic cell cycle, the history of cancer, oncogenes, tumor suppressors, and

cancer-causing viruses. The laboratory will complement the lectures and introduce the student to cell

culture. Lecture: 3 hours/Lab: 3 hours/week Prerequisites: BLG 307, BLG 311, and BLG 411; Course


BMS 860 Stem Cell Biology (NEW COURSE)

This course will examine the molecular and cell biology of stem cells and their importance in

development and maintenance of adult tissues like blood and skin. Additionally, the course will discuss

topics such as pluripotency, a discussion and comparison between embryonic and adult stem cells,

induced pluripotency and the ethical issues related to stem cell use in medicine. Lecture: 3 hours/week.

Prerequisites: BCH 361, BLG 307, BLG 411, and BLG 600. Course Weight: 1.00 Billing Units: 1

Appendix A3: Professional and professionally-related core electives

Table X (section 1.3) contains Core Electives, of which a minimal of three (3) courses must be chosen

from. Below is listed in alphabetical order the courses for that table. New courses are indicated. To be

able to offer this number of new courses, we envision that many will run in alternating years. This system

is used in many institutes to provide flexibility of teaching responsibilities for research faculty.

BCH 362 Advanced Biochemistry II

The major topics introduced in the lectures are membrane structure and transport systems and the

metabolism of lipids, proteins and nucleic acids. A review of DNA replication and protein synthesis will

also be included. The laboratory focuses on chromatography and electrophoresis as used to separate and

analyze proteins. Students are required to write a major report(s), make an oral presentation and present a

poster. (Formerly CHY 362). Lect: 3 hrs./Lab: 3 hrs. Prerequisite: CHY 361 or BCH 361 Course Weight:

1.00 Billing Units: 1

BCH 501 Protein Biochemistry and Proteomics

In depth examination of protein structure and function, tools for determining biochemical function and

structure, analysis of protein-protein interactions, regulatory mechanisms, introduction to high throughput

identification and quantification of protein expression; application of proteomics to drug design. Lect: 3

hrs. Prerequisites: BCH 261 and BCH 361 Course Weight: 1.00 Billing Units: 1

BCH 580 Cell Signalling

The course provides a survey of signal transduction. Topics include: intracellular, intercellular and

signaling between tissues and organs; biophysics and calculation of ligand receptor binding; signaling of

prokaryotes required for quorum, chemical and nutrient detection, signaling transduction of mammalian

senses and nervous systems. A survey of mammalian signal transduction including the cell surface

receptors, the Ig superfamily and cancer signal mechanisms will be presented. Lect: 3 hrs. Prerequisite:

BLG 311 and (CHY 261 or BCH 261)


BLG 251 Microbiology II

This course introduces the student to more in depth information about the microbial world. Topics include

microbial genetics, gene regulation and expression and microbial metabolism. These are followed by a

complete survey of microbial systematics and virology. The impact of microorganisms on the world will

then be discussed including microbial diseases, environmental issues and industrial applications.

Laboratory exercises complement the lectures and familiarize the student with genetic manipulation of

bacteria, replication of viruses and systematic approaches to microbial identification. Lect: 3 hrs./Lab: 3

hrs. Prerequisite: BLG 151 Course Weight: 1.00 Billing Units: 1

BLG 408 Viruses

This course will begin with a short history of virology, then move to an overview of virus replication

strategies, with sample viruses from each of the Baltimore classification categories. Prions as well as

other unusual infectious elements will also be introduced. The course will emphasize viruses for which

Public Health Canada recommends immunization, and end with viruses for which there is no cure. Lect: 3

hrs. Prerequisites: BLG 143 and BLG 144 and (CHY 261 or BCH 261) Course Weight: 1.00 Billing

Units: 1

BLG 409 Biometry










This course will cover commonly used statistical analyses of biological data, working with data structures

familiar and relevant to Biology majors. The course will focus on experimental design, training students

to set up experiments with a priori consideration of statistical analysis. Specific topics will include

probability, distribution analysis, measures of central tendency, confidence intervals, hypothesis testing,

regression and correlation analyses, multiple regression models, chi-square tests, t-tests, analysis of

variance (ANOVA) models, power analyses. Lect: 3 hrs. Prerequisite: BLG 143 and BLG 144 Course


BLG 578 Pharmacology

The pharmacological and biochemical basis of drug absorption, distribution, metabolism,

biotransformation, toxicity and susceptibility. Topics include physiological effects, modes of delivery,

chemical carcinogenesis and mechanism of action and cellular resistance to antibacterial and anticancer

drugs. Lect: 3 hrs. Prerequisites: BLG 143 and BLG 144 and BLG 311 and (CHY 361 or BCH 361)


BLG 678 Current Topics in Biology

Recent developments and topics of current interest in biology and their applications will be included. A

variety of instructional modes will be used e.g. lecture, seminar, guest speakers, student presentations,

demonstration and practice. Lect: 3 hrs. Prerequisites: BLG 888 and (CHY 362 or BCH 362) Course


BLG 700 Anatomy

This course takes a systematic approach to the structure of the human body at the gross and microscopic

levels. Areas of focus include tissues, the integumentary, skeletal, muscular and nervous systems, and

embryology. Lect: 3 hrs. Prerequisites: BLG 143 and (BLG 144 or CEN 100) Course Weight: 1.00

Billing Units: 1

BLG 702 Genomics and its Applications

The relationship between the structure and function of a gene in both prokaryotes and eukaryotes;

contents of various genomes, identification and implications; review of the Human Genome project; tools

used in discovering and identifying sequences in a particular genome; analysis of gene expression. Lect: 3

hrs. Prerequisites: BLG 400 and BLG 307 Course Weight: 1.00 Billing Units: 1

BLG 785 Developmental Biology

An introduction to the study of development of plants and animals both at the organism and molecular

level. Topics include sequential morphological changes and gene expression during development, sexual

maturation and the aging process. Lect: 3 hrs. Prerequisites: BLG 311 and (CHY 261 or BCH 261)


BLG 788 Current Topics in Biotechnology

This course emphasizes the biological synthesis of commercial products, the genetic engineering of plants

and animals. Topics will also include DNA fingerprinting analysis in forensics and diagnostics and

production of recombinant vaccines. (BLG 407 is equivalent to BLG 788 plus BLG 888). Lect: 3 hrs.

Prerequisite: BLG 307 Course Weight: 1.00 Billing Units: 1

BLG 800 Genomics and Proteomics

An introduction to genomics and proteomics; relationship between structure and function of a gene; tools

used in discovering and identifying sequences in a particular genome; an overview of protein structure

and function, tools for structural determination, analysis of protein-protein interactions, introduction to

the high throughput identification and quantification of protein expression; review of the Human Genome



















project; application of genomics and proteomics to drug design. Lect: 3 hrs. Prerequisites: BLG 311 and

BLG 400 and (CHY 261 or BCH 261) Course Weight: 1.00 Billing Units:1.

BME 501/CPS 501 Bioinformatics

Introduction to analysis, management, and visualization of cellular information at the molecular level.

The course includes an overview of mathematical modeling and simulation, pattern matching, methods

for phylogenetics, gene recognition, distributed and parallel biological computing, designing and

managing biological databases (both relational and object-oriented), linking disparate databases and data,

data mining, reasoning by analogy, hypothesis formation and testing by machine. Lect: 3 hrs.

Prerequisite: BLG 143 and (CPS 125 or CPS 118), Antirequisite: CPS 501 Course Weight: 1.00 Billing

Units: 1

*BMS 40A/B Project-Thesis

A research project supervised by a faculty member. An oral presentation of results and a thesis are

required. Registration in this course may be restricted by the number of available projects. Lect: 3 hrs.

Departmental consent required Course Weight: 2.00 Billing Units: 1/1.

*Same instructor can coordinate both BMS 40A/B and BLG40A/B concomitantly with little demand on

resources

BMS 607 Molecular Genetics and Epigenetics (NEW COURSE)

A discussion on current aspects of molecular genetics including: chromosome structure and function,

inheritance of mutations and disease, the human genome and disease gene mapping. This course will also

cover the study of heritable changes in gene expression that occur without a change in DNA sequence, or

epigenetics. This course will address the basic principles of epigenetics, the role of epigenetic

mechanisms in normal development and human disease with emphasis on the role of chromatin structure.

Lecture: 3 hours/week. Course Weight: 1.00 Billing Units:1.

Prerequisites: BLG 400 and BLG 307. Course Weight: 1.00 Billing Units: 1

BMS 857 Advanced Immunology (NEW COURSE)

This course will provide an overview of immunopathology, transplantation, autoimmunity and tumour

immunology. It will include an introduction to the genetics and cellular pathogenesis of autoimmune

diseases such as type I diabetes and multiple sclerosis. Also included will be the pathogenesis and the

treatment of immune-related conditions such as Crohn’s Disease and HIV as well as transplantation and

graft rejection. Lecture: 3 hours/week Pre-requisite: BLG 856. Course Weight: 1.00 Billing Units: 1

BCH 461 Biochemistry of Disease (NEW COURSE) This course will examine the etiology and pathogenesis of biochemical disorders of diseases. The course

will include applications of biochemistry, chemistry and immunology as they relate to the diagnosis,

therapy, and monitoring of human disease. Lecture: 3 hours/week. Prerequisite: BLG 400, BCH 361.


BMS 451 Medical Microbiology (NEW COURSE) This course will deal with the study of microorganisms including bacteria, viruses, fungi and parasites

which are of medical importance and are capable of causing diseases in human or animals. It includes the

laboratory diagnosis of human and animal infections and the role of the laboratory in both the

management of infectious diseases and the elucidation of the epidemiology of infections. Lecture: 3

hours/week. Prerequisite: BLG 151, BLG 856. Course Weight: 1.00 Billing Units: 1

BMS 605 Advanced Physiology (NEW COURSE)








The regulation of physiological processes by hormones and other signalling molecules in chordates will

be discussed. An integrated genes-to-environment approach is used to examine aspects of hormonal

evolution, physiological information flow, behaviour and neuroendocrinology, and xenobiotic endocrine

disruptors. Lectures: 3 hours/week Prerequisites: BCH 261, BLG 411, BLG 600. Course Weight: 1.00

Billing Units: 1

BMS 858 Infection and Immunity (NEW COURSE) The primary focus of this course is the interactions between mammalian-specific bacterial, fungal and

protozoan pathogens and their hosts. The course will examine molecular mechanisms underlying

pathogen-host recognition, pathogen invasion of host cells and hijacking of host cell signalling. The

molecular basis of the host immune response to pathogens and how pathogens interact with, modify

and/or evade the immune system will also be covered. The course will conclude with a review of

appropriate versus inappropriate host immune responses to infectious and non-infectious agents and how

these responses contribute to the outcomes of infectious diseases and several infection-related

autoimmune. Lecture: 3 hours/week. Prerequisite: BLG 151, BLG 411, BLG 856. Course Weight: 1.00

Billing Units: 1

BMS 500 Human Genetics (NEW COURSE) This course will include current aspects of human and molecular genetics including: chromosome

structure and function, inheritance of mutations and disease, the human genome and disease gene

mapping, cancer genetics, mouse disease models and gene based diagnostics and therapies. It will

examine approaches used in genetic screening, genetic counselling and genetic therapy. Lecture: 3

hours/week. Prerequisites: BCH261, BLG411 and BLG400. Course Weight: 1.00 Billing Units: 1

BMS 770 Medical Epidemiology (NEW COURSE) This course will present an overview of epidemiology - uses, methods, and data sources. It will include an

overview of types of human genetic variation, approaches to gene discovery vs. gene characterization. It

will also cover the epidemiology behind flu vaccine development and the spread of infectious diseases.

Lecture: 3 hours/week. Prerequisites: MTH 380. Course Weight: 1.00 Billing Units: 1.

BMS 865 Model Organisms (NEW COURSE) An introduction and discussion of the various model organisms employed in the life sciences from the

unicellular organisms like E. coli and Baker’s yeast to simple and complex multicellular organisms like

Drosophila, C. elegans, mouse and Arabidopsis. The course will discuss major discoveries made with

these organisms, their advantages and disadvantages and maintain a historical perspective on the use of

these organisms. Lecture: 3 hours/week. Prerequisite: BLG 311, BLG151, BLG 400. Course Weight: 1.00

Billing Units: 1

BMS 870 Neurobiology (NEW COURSE) This course will examine the development, anatomy and function of the nervous systems in various

organisms with emphasis on humans and its relationship to behavior and disease. Neuronal structure and

function including synapses and neurotransmitters will be discussed. Sensory perception and motor

responses will be examined. The current understanding of higher order functions of cognition, learning,

memory and communication will be explored. Lecture: 3 hours/week. Prerequisite: BLG 600, BLG 311,

BLG 411.

Lecture: 3 hours/week Prerequisite: BLG 600. Course Weight: 1.00 Billing Units: 1

BMS860 Stem Cell Biology

This course will examine the molecular and cell biology of stem cells and their importance in

development and maintenance of adult tissues like blood and skin. Additionally, the course will discuss

topics such as pluripotency, a discussion and comparison between embryonic and adult stem cells,

induced pluripotency and the ethical issues related to stem cell use in medicine. Lecture: 3 hours/week.

Prerequisites: BLG 411, BCH 361, BLG 307, BLG 600. Course Weight: 1.00 Billing Units: 1

MTH 231 Modern Mathematics II

Implicit functions and differentiation. Related rates, concavity, inflection points and asymptotics.

Optimization. L'Hôpital's rule. Applications of integration. Techniques of integration. Numerical

integration. Functions of 2 or more variables, partial derivatives. Linear Algebra: Higher-order

determinants, introduction to n-dimensional space, inner product, projections, cross product, lines and

planes in 3-dimensional space.

Lect: 4 hrs./Lab: 1 hr. Prerequisite: MTH 131 Course Weight: 1.00 Billing Units: 1

CHY 242 Organic Chemistry II

This course includes the mechanistic approach to the study of organic reactions and includes condensation

reactions, aromatic chemistry and pericyclic reactions. Also included are spectroscopic methods of

structure determination, organic synthesis and the use of organometallic reagents. Lect: 3 hrs.

Prerequisite: CHY 142 Course Weight: 1.00 Billing Units: 1

CHY 436 Pharmaceutical Chemistry

This course provides an introduction to medicinal chemistry. Topics examined include classification,

pharmacokinetics, mechanisms of action (pharmacodynamics), interactions, formulations, production and

design of drugs, including biotechnology drugs. Drugs are grouped by their common mechanism(s) of

action and discussed as such. Lect: 3 hrs. Prerequisite: CHY 261 Course Weight: 1.00 Billing Units: 1

PCS 229 Introduction to Medical Physics Applications of physics in medicine. This survey course will address basic concepts of medical imaging,

nuclear medicine and radiation isotopes, radiation therapy, gamma spectroscopy and trace element

analysis, and biomedical laser applications. Lect: 3 hrs. Prerequisite: PCS 130 and MTH 131,

Antirequisite: BME 229

PCS 227 Biophysics

Biomechanics principles. Physics of hearing and vision. Fluid mechanics and human circulatory system.

Viscosity and viscoelasticity in biological fluids. Thermodynamics of biochemical reactions and

metabolism. Random molecular motion in gases and solutions. Electrolytes. Molecular and ionic

interactions in solutions. Membrane's structure and properties. Diffusion and osmosis in biological

organisms. Electrochemistry of cells. Action potential and electrical activity of neurons. Lect: 3 hrs.

Prerequisite: PCS 130 and MTH 131 Course Weight: 1.00 Billing Units: 1

PCS 230 Photonics and Optical Devices

This course is designed to provide students with direct experience in the operation of optical devices that

find widespread use in the technology sector. Emphasis is placed on geometric optics, laser systems,

image formation, fiberoptics, diffraction and interference. Lect: 3 hrs./Lab: 1.5 hrs. Prerequisite: PCS 130

and MTH 231 Course Weight: 1.00 Billing Units: 1

PCS 300 Modern Physics

Special Relativity: simultaneity, time dilation, length contraction, Lorentz transformations, velocity

addition, rest mass, energy. Blackbody radiation: Boltzmann's and Wien's Laws, Planck's quantization.

Photoelectric effect. Compton effect. Atomic spectra. Rydberg's formula. Thompson's and Rutherford's

atomic models. Bohr's model of the atom. Lect: 3 hrs./Lab: 1 hr.

Prerequisites: MTH 231 and PCS 130 Course Weight: 1.00 Billing Units: 1

PCS 352 Nuclear Physics/Radiation Protection












Introduction to nuclear physics. Nuclear structure and binding energy. Nuclear decays, radioactivity and

nuclear reactions. Interaction of radiation with matter. Introduction to dosimetry and dose calculations.

Tut: 1 hr./Lect: 3 hrs./Lab: 1.5 hrs. Prerequisite: (PCS 300 and MTH 380) or (PCS 300 and CHY 223).

PCS 354 Radiation Biology Introduction to basic physics and chemistry of radiation interactions, free radicals, oxidation and

reduction. Subcellular and cellular effects: killing, repair, sensitization and protection. Measurement

methods. Survival curves and their significance. Modification of the radiation response. Tissue effects,

genetic and carcinogenic effects, mutations, hazards. Effects of heat on tissue. Thermal dosimetry.

Biology of Thermal Potentiation of Radiotherapy. High temperature thermal therapy. Lect: 3 hrs.

Prerequisite: PCS 229 and BLG 311.

PCS XX1: Cellular Biophysics (NEW COURSE): This course presents physical principles important to

the operation of biological systems such as entropy, diffusion, cellular electricity, cellular motor forces,

mechanical properties of the cell, and selected topics from radiation biophysics, biological switches,

sensory physics, waves, self organization, and biological complexity. Pre-requisite: PCS 227.

PCS XX2: Nanophysics (NEW COURSE). Introductory course on nanotechnology and applications in

biology and medicine. Physics at nano-scale of nano-particles and nano-devices; fabrication and

characterization of nanostructures; magnetic and optical effects at nano-scale; transport properties;

nanotechnology. Pre-requisites: PCS 227.

PSY 202 Introduction of Psychology II

This course continues the introduction to psychology from PSY 102, with a focus on applying

psychological principles in different contexts. The course surveys some core areas of psychology,

including personality, development over the life span, behaviour in a social context, and psychological

disorders. Lect: 3 hrs. Prerequisite: PSY 102, Restriction: NU005, NU007 Course Weight: 1.00 Billing

Units: 1

PSY 214 Psychopharmacology

This course examines a variety of issues surrounding the use, mechanisms, and actions of psychoactive or

mind-altering drugs. The course focuses on two main contextual topic areas: drug addiction, and drug

treatment of mental illness. Each of these areas is explored in depth, including the role of genes,

biochemistry, cognition, and personality factors. Lect: 3 hrs. Prerequisite: PSY 11 or PSY 105 or PSY

102, Antirequisite: PSY 607 Course Weight: 1.00 Billing Units: 1

PSY 215 Psychology of Addictions

This course introduces students to basic principles and issues in the area of addiction, the factors that

influence its development, and the methods used to treat it. The similarities and differences between

addictive disorders and other forms of psychopathology are discussed. The course studies both

experimental and clinical approaches to addiction. The course covers the various instruments and methods

used by addiction researchers and clinicians and discusses their strengths and weaknesses. Lect: 3 hrs.

Prerequisite: PSY 11 or PSY 105 or PSY 102 Course Weight: 1.00 Billing Units: 1

PSY 324 Biological Psychology

This course is concerned with integrating the understanding of human behaviour and the understanding of

physiological mechanisms relating to behaviour, particularly those of the nervous system and brain.

Students are introduced to neurons and neurophysiology, neuroanatomy, neurochemistry, and the

methods used in physiological research. These core areas allow students to understand how nervous

system mechanisms contribute to sensorimotor function, ingestion, sexual behavior, memory, thought,















language and consciousness, addictions and psychological disorders. Lect: 3 hrs. Prerequisite: PSY 11 or

PSY 105 or PSY 102 Course Weight: 1.00 Billing Units: 1

PSY 325 Psychological Disorders

This course examines conceptions of abnormality, how psychological disorders are classified, and how

they are treated. The DSM classification system and alternative systems will be critically considered, and

the causes of psychological disorders will be discussed from a variety of perspectives (e.g., behaviourist,

humanist, sociocultural). Specific disorders to be discussed include mood disorders, schizophrenia,

substance-related disorders, somatoform and dissociative disorders, personality disorders, eating

disorders, and anxiety disorders. In addition, the course includes consideration of cross-cultural factors,

and legal and ethical issues. (Formerly the first half of PSY 040.) Lect: 3 hrs. Prerequisite: PSY 11 or

PSY 105 or PSY 102, Antirequisite: PSY 606 Course Weight: 1.00 Billing Units: 1






table 1. curriculum for biomedical science program curriculu… · table 1. curriculum for...

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