system workflow urinary tract infection (uti) cartridge · working time 60 seconds working time 20...

Working time 60 seconds



Transfer patient sample to Unyvero Sample Tube

Scanning and inserting the Unyvero Cartridge in the A50

(Max. 2 cartridges simultaneously)

Results displayed in Cockpit – PDF export

30 minutes lysis in Lysator

Assembling Unyvero Cartridge with Sample and Master Mix Tube

Panel Overview

System WorkflowUnyvero L4 Lysator Unyvero C8 Cockpit Unyvero A50 Analyzer

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C

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Curetis GmbH | Max-Eyth-Str. 42 | 71088 Holzgerlingen | Germany

Tel.: +49 (0)7031 49195 10 | Email: [email protected] |

Unyvero is designed to expand with your growing needs

00299 Rev 7.0 © Curetis GmbH

Caution – Investigational Device. Limited by Federal US Law to investigational Use. Not available for Sale in the United States.

www.curetis.com

Blood Culture – BCU

Hospitalized Pneumonia – HPN

Implant & Tissue Infection – ITI

Intra-Abdominal Infection – IAI

Urinary Tract Infection – UTI

Urinary Tract Infection (UTI) Cartridge

Staphylococcus aureus

Coagulase negative staphylococci

Staphylococcus saprophyticus

Streptococcus agalactiae

Enterococcus spp.

Enterococcus faecalis

Enterococcus faecium

Corynebacterium urealyticum

Gram-positive bacteria

Enterobacteriaceae

Citrobacter freundii / koseri

Enterobacter aerogenes

Enterobacter cloacae complex

Escherichia coli

Klebsiella oxytoca

Klebsiella pneumoniae

Klebsiella variicola

Proteus spp.

Providencia spp.

Enterobacteriaceae

Candida spp.

Candida albicans

Candida auris

Candida glabrata

Fungi

GeneResistance

Acinetobacter baumannii complex

Pseudomonas aeruginosa

Non-fermenting bacteria

Detection of prokaryotic genetic sequence

Universal Bacteria

Bacteroides spp. / Prevotella spp.

Anaerobic bacteria

mecA

vanA vanB

ctx-M

imp kpc ndm oxa-23 oxa-24/40 oxa-48 vim

mcr-1

qnrB qnrS

sul1

3rd generation Cephalosporins

Glycopeptides

Fluoroquinolones

Sulfonamide

Carbapenem

Polypeptides / polymyxins

Oxacillin

Urine (mid-stream, suprapubic, fresh catheter) and tissue.

Sample Types

*88 Pathogens, 15 Resistance Genes

4 to 5 hour analysis process

103*



Streptococcus spp.


Streptococcus pneumoniae

Streptococcus pyogenes / dysgalactiae

Enterococcus spp.


Listeria monocytogenes




Streptococcus spp.



Streptococcus pyogenes /dysgalactiae

Granulicatella adiacens

Abiotrophia defectiva

Enterococcus spp.





Enterococcus spp.

Streptococcus spp.







Escherichia coli



Klebsiella oxytoca



Proteus spp.

Serratia marcescens

Enterobacteriaceae

Corynebacterium spp.


Escherichia coli




Klebsiella oxytoca


Proteus spp.


Citrobacter freundii

Escherichia coli



Proteus spp.


Klebsiella oxytoca


Serratia marcescens

Morganella morganii

Corynebacteriaceae

Enterobacteriaceae

Universal Bacteria

Enterobacteriaceae

Aspergillus spp.

Candida spp.

Candida albicans

Candida dubliniensis

Candida glabrata

I. orientalis (C. krusei)

Candida parapsilosis

Candida tropicalis

Candida spp.

Candida albicans

Candida glabrata

I.orientalis (C.krusei)

Candida tropicalis

Candida spp.

Candida albicans

Candida glabrata

Candida tropicalis

Issatchenkia orientalis (Candida krusei)

Fungi Fungi

Fungi

GeneResistance

aac(6´)/aph(2´´) aacA4

ermA

mecA mecC

vanA vanB

ctx-M

imp kpc ndm oxa-23 oxa-24/40 oxa-48 oxa-58 vim


Carbapenem

Macrolide/ Lincosamide

Oxacillin

Glycopeptides

Aminoglycoside

Gene

Gene

Resistance

Resistance

GeneResistance



Stenotrophomonas maltophiliaAcinetobacter baumannii complex


Moraxella catarrhalis



Stenotrophomonas maltophilia

Legionella pneumophilaNon-fermenting bacteriaNon-fermenting bacteria

Non-fermenting bacteria


Universal Bacteria

Haemophilus influenzae

Neisseria meningitidis

Corynebacterium spp.




Escherichia coli




Klebsiella oxytoca


Proteus spp.Other Gram-negativebacteria

Corynebacteriaceae

Non-fermentingbacteria

Universal Bacteria

Enterobacteriaceae

Mycobacterium spp.

Mycobacteriaceae

Propionibacterium acnes


Finegoldia magna

Bacteroides fragilis group

Aeromonas spp.

Bacteroides fragilis group

Bacteroides spp. / Prevotella spp.

Clostridium difficile

Clostridium perfringens

Finegoldia magna


Pneumocystis jirovecii

Haemophilus influenzae

Mycoplasma pneumoniae

Chlamydophila pneumoniae

Anaerobic bacteriaAnaerobic bacteria

Anaerobic/facultativeanaerobic bacteria

Others/Fungi

Blood Culture (BCU) Cartridge Hospitalized Pneumonia (HPN) Cartridge Implant & Tissue Infection (ITI) Cartridge Intra-Abdominal Infection (IAI) Cartridge

ermB

mecA mecC

tem shv

ctx-M


sul1

gyrA83 gyrA87

Oxacillin

Penicillin

Carbapenem

Sulfonamide

Fluoroquinolone


Macrolide/Lincosamide

Oxacillin

Aminoglycoside

Carbapenem

Glycopeptides


Macrolide/Lincosamide

ermA ermC

aac(6´)/aph(2´´) aacA4

mecA mecC

vanA vanB

ctx-M


MarkerToxin

Shiga Toxin stx1/2

Toxin B tcdB

mecA mecC

vanA vanB

aacA4

ctx-M

fosA3

mcr-1

nimA nimB

qnrA qnrB qnrS

tetA


Glycopeptides

Aminoglycoside

Tetracycline

Carbapenem

Fosfomycin

Polypeptides/polymyxins

Nitroimidazole

Fluoroquinolone


Oxacillin

Ascites and peritoneal fluid, pancreatic juice, bile, tissue, puncture fluid,swabs, catheter/drainage tips, and samples from positive blood culturebottles that have been inoculated with ascites/puncture fluid.

Sonication fluids, swabs, tissue, pus, aspirate/exudate, bone fragments, etc.Sputum, bronchoalveolar lavage, tracheal aspiratesPositively flagged blood cultures

Sample Types Sample Types Sample Types Sample Types

*105 Pathogens, 3 Toxins, 22 Resistance Genes*85 Pathogens, 17 Resistance Genes*86 Pathogens, 17 Resistance Genes *29 Pathogens, 19 Resistance Genes

103* 102* 130*48*

system workflow urinary tract infection (uti) cartridge · working time 60 seconds working time 20...

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