swell1, a plasma membrane protein, is an essential component of volume- regulated anion channel...

16
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu, Kritika Reddy, Loren J. Miraglia, Jürgen Reinhardt, Anthony P. Orth, Ardem Patapoutian Cell Volume 157, Issue 2, Pages 447-458 (April 2014) DOI: 10.1016/j.cell.2014.03.024 Copyright © 2014 Elsevier Inc. Terms and Conditions

Upload: magnus-barton

Post on 04-Jan-2016

215 views

Category:

Documents


1 download

TRANSCRIPT

Page 1: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel 

Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu, Kritika Reddy, Loren J. Miraglia, Jürgen Reinhardt, Anthony P. Orth, Ardem Patapoutian 

Cell Volume 157, Issue 2, Pages 447-458 (April 2014)

DOI: 10.1016/j.cell.2014.03.024

Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 2: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure 1

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 3: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure 2

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 4: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure 3

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 5: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure 4

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 6: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure 5

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 7: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure 6

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 8: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure 7

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 9: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure S1

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 10: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure S2

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 11: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure S3

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 12: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure S4

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 13: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure S5

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 14: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure S6

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 15: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Figure S7

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions

Page 16: SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume- Regulated Anion Channel Zhaozhu Qiu, Adrienne E. Dubin, Jayanti Mathur, Buu Tu,

Cell 2014 157, 447-458DOI: (10.1016/j.cell.2014.03.024) Copyright © 2014 Elsevier Inc. Terms and Conditions