supplementary figure 1

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Supplementary Figure 1 65 70 75 80 85 90 40 44 48 52 56 30 40 50 60 70 80 90 25 30 35 40 45 50 55 50 60 70 80 90 38 40 42 44 46 48 50 52 Methylation Level of LINE1 (%) Normal Background ESCC Methylation Level of Alu (%) Methylation Level of LINE1 (%) Methylation Level of LINE1 (%) r = 0.043 p = 0.678 r = 0.063 p = 0.559 r = 0.502 p < 0.001

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90. 85. 80. 75. 70. 65. 40. 44. 48. 52. 56. 90. 80. 70. 60. 50. 38. 40. 42. 44. 46. 48. 50. 52. 90. 80. 70. 60. 50. 40. 30. 25. 30. 35. 40. 45. 50. 55. Normal. r = 0.043. p = 0.678. Methylation Level of LINE1 (%). Background. r = 0.063. p = 0.559. - PowerPoint PPT Presentation

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Page 1: Supplementary Figure 1

Supplementary Figure 1

65

70

75

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90

40 44 48 52 56

30

40

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60

70

80

90

25 30 35 40 45 50 55

50

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90

38 40 42 44 46 48 50 52Met

hyla

tion

Leve

l of L

INE1

(%)

Normal

Background

ESCC

Methylation Level of Alu (%)

Met

hyla

tion

Leve

l of L

INE1

(%)

Met

hyla

tion

Leve

l of L

INE1

(%)

r = 0.043p = 0.678

r = 0.063p = 0.559

r = 0.502p < 0.001

Page 2: Supplementary Figure 1

Supplementary Figure 2

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100

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0

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0

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Met

hyla

tion

Leve

l (%

)

Normal Background ESCC

HOXA9

Met

hyla

tion

Leve

l (%

)

UCHL1 MT1M

a b

dc

NEFH

(n = 95) (n = 89) (n = 93)Normal Background ESCC(n = 95) (n = 89) (n = 93)

Normal Background ESCC(n = 95) (n = 89) (n = 93)

Normal Background ESCC(n = 95) (n = 89) (n = 93)

p < 0.001

p < 0.001

p < 0.001

p < 0.001

p < 0.001

p < 0.001

p < 0.001

p = 0.018

p < 0.001

p < 0.001

p = 0.276

p = 0.118

Page 3: Supplementary Figure 1

a b

c

Supplementary Figure 3