WELCOME

BRAIN TONICS

–Under the guidance of– Dr. T.Vedavathi– M.Pharm,Phd– Professor– CMR College Of Pharmacy

By K.Sujana Regd.No.10T22S0116 M.Pharm 1st Year (P’cology) CMR College of Pharmacy

BRAIN TONICS

BRAIN TONICS

CONTENTS

• INTRODUCTION• BRAIN TONICS• BRAIN TONIC & MEMORY BOOSTER

HERBS• FORMULATION OF BRAIN TONIC• CONCLUSION• BIBILIOGRAPHY

INTRODUCTION

• The human brain is one of the most sophisticated organs nature has ever made. One of the most interesting aspects of the brain is its power to retain information, which we call as memory. Memory is perhaps the most vital of the aspects that differentiates human beings from other animals.

BRAIN TONICSDEFINITION: Brain Tonic is a natural remedy to improve concentration,balance mood and memory problems and also for those who are studying or under work stress in all ages.• It is useful for patients sufferings from lack of

concentration and low memory performance. It is also useful for Alzheimers patients.

Alzheimer's disease

• Alzheimer's disease (AD), is one form of dementia that gradually gets worse over time. It affects memory, thinking, and behavior.

Causes, incidence, and risk factors:• Age and family history are risk factors for AD. • As you get older, your risk of developing AD goes up.

However, developing Alzheimer's disease is not a part of normal aging.

 • Having a close blood relative, such as a brother, sister, or

parent who developed AD increases your risk.

Two abnormal structures called plaques and tangles are prime suspects in damaging and killing nerve cells.

There are two types of AD -- early onset and late onset• In early onset AD, symptoms first appear before

age 60. Early onset AD is much less common than late onset. However, it tends to progress rapidly. Early onset disease can run in families. Several genes have been identified.

• Late onset AD, the most common form of the disease, develops in people age 60 and older. Late onset AD may run in some families, but the role of genes is less clear.

The early symptoms of AD can include• Language problems, such as trouble finding the name of

familiar objects• Misplacing items • Getting lost on familiar routes • Personality changes and loss of social skills • Losing interest in things previously enjoyed, flat mood

As the AD becomes worse, symptoms are more obvious and interfere with your ability to take care of yourself. Symptoms can include

• Forgetting details about current events• Change in sleep patterns, often waking up at night

People with severe AD can no longer:

• Understand language• Recognize family members • Perform basic activities of daily

living, such as eating, dressing, and bathing 

• USES OF BRAIN TONICS:

• Relieves mental stress and anxiety.

• Ideal for students and elderly people.

• Prevents early ageing of brain cells

• Improves functioning of other organs by stimulating central nervous system.

• Improves concentration and memory

• Increases blood flow to the brain

• Reduces the frequency of headaches

• Supports systemic balance on a cellular level

GINGKO •Also known as Maiden hair tree,Kew tree

• FAMILY :Gingkoaceae •BIOLOGICAL SOURCE: Dried leaves of Gingkobiloba

• CHEMICAL CONSTITIUENTS: flavonol glycosides and triglycosides of quercetin,kaempferol and iso rhametin.

• Medicinal uses

• Ginkgo works by improving the blood circulation to the central nervous system.

• It also minimizes the effects of the blood clotting.

• The extract of the ginkgo is prescribed to people who have amnesia and Alzheimer’s disease.

• Several herbal brain tonics have ginkgo as one of the chief ingredients.

Ginkgo biloba

DOSAGE : gingko supplements are usually taken in the range of 40-200mg per day.

LIQUORICE• Also known as yastimadhu,Mulethi.• FAMILY: Leguminosae

• BIOLOGICAL SOURCE: dried unpeeled roots and stolons of glycyrrhizaglabra.

CHEMICAL CONSTITUENTS:• triterpinoid saponin glycyrrhizin,

potassium and calcium salts of glycyrrhizinic acids

• Another important chemical aspect of liquorice is the presence of flavonoids.

• A compound carbenoxolone is derived from liquorice.

Uses:• Mulethi is an efficient brain tonic and

a re-vitalizer for the brain. mulethi also rejuvenates the brain.

• Mulethi is frequently provided to students who are preparing for important examinations,as it helps to remember small facts and bits of information. 

DOSAGE: Generally,1-2cups of liquorice tea is taken per day. And recommended dose,tincture: 1/2-1teaspoonful twice a day taken before meals.

ASHVAGANDHA• Also known as withania root,winter

cherry.BIOLOGICAL SOURCE: Stem bases of Withania Somnifera.• FAMILY : SOLANACEAE • contains alkaloids and Steroidal lactones. • Withanine is the main Constituent.

• Also contains monohydric Alcohols and fatty acids.

USES:• Ashwagandha is one of the most

essential components used in enhancing memory and overall brain functioning.

• Ashwagandha is an adaptogen,stress-buster and a re-vitalizer.

• Ayurveda regards ashwagandha as a medha rasayana,i.e. a brain tonic.

• It is a vital component of almost all herbal brain tonics available in the market. 

DOSAGE: 1 or 2 capsules twice everyday with meals.- oral administration of ashwagandha for five days suggested that anxiety-relieving effects similar to those achieved by the anti-anxiety drug lorazepam.

CENTELLA ASIATICA • Also known as Gotu

kola,mandukparni, SaraswathiPlant BIOLOGICAL SOURCE:It has long-stalked, green reniform leaves of centella asiatica.

• FAMILY: mackinlayaceae

CHEMICAL CONSTITUENTS: • The primary constituents of gotu

kola are triterpenoid compounds.• The major triterpenoid components

are: asiatic acid, madecassic acid, asiaticoside and madecassoside.

• The plant is also a source of calcium and sodium.

USES• The gotu kola is very effective in increasing the

circulation of blood to brain. It protects the brain from damage due to the wear and tear of its cells. 

• Gotu kola is generally used in tonics intended to re-vitalize the brain. It improves concentration. 

• Centellaasiatica may be useful in the treatment of Anxiety and may be used as a promising anxiolytic agent in the future. 

DOSAGE: 1 or 2 capsules twice daily with meals.

ACORUS CALAMUS• Also known as calamus root or sweet

flagBIOLOGICAL SOURCE: Dried rhizomes

of the plant known as Acorus calamus.

Family: AraceaeCHEMICAL CONSTITUENTS :The drug

contains 1.5 to 3.5% of volatile oil contains asaraldehyde.The other contents of the oil are asarone and eugenol.Calamus also contains a bitter amorphous principle known as acorine.The other constituents are Hydrocarbons ,trimethylamine,beta-asarone,camphone.

Uses:

• Vacha is a very vigorous brain tonic, because it shows results in a very short time. It increases the overall memory of the person and strengthens the nervous system.Vacha is prescribed to people who have amnesia.

• It also increases blood supply to brain and oxygenates it.

DOSAGE:• The root or rhizome can be chewed

or to be taken a pinch of powder in teaspoonful of honey.

BACOPA MONNIERI• Known as BRAHMIBIOLOGICAL SOURCE:• Contains of fresh and dried leaves and

stems of the plant bacopa monnieri.• Family: Scrophulariaceae CHEMICAL CONSTITUENTS :• contains alkaloids bramine and saponins

namely bacosides A & B• it also contains betulic acid, stigmasterol,

monnierin and hersaponin .

USES:

• Brahmi is used as nerve tonic and treatment of epilepsy.

• Improves memory and enhances recall.• Increases concentration and intellect. • Increases brain capacity to take additional

load.• Relives mental stress and strain.

DOSAGE : suggested dose: Adults powder: 2 teaspoonsful twice a day in milk. capsule-:1 capsule twice a day preferably with milk. Children : 1-2 teaspoonsful twice a day in milk.

CONVOLVULUS PLURICAULIS • Also known as shankhapushpi,

bindweed.• Family:  Convolvulaceae BIOLOGICAL SOURCE :areial parts

of plant convolvulus pluricaulis.CHEMICAL CONSTITUENTS;contains many phytonutrients like

convolidine,convolvineconvoline,confoline,phyllabine,subhirsine, sitosterol and

scopoline

• These compounds help brain stimulation and increase the ability to concentrate

USES: • Shankhapushpi has been regarded as

powerful brain tonic,a natural memory stimulant, and a good tranquilizer.

• It is also used as a rasayana and rejuvenator. • Shankhapushpi reduces anxiety and stress by

controlling the production of body's stress harmones,adrenaline and cortisol.

• This plant also significantly enhances memory power and intelligence. Its powder,mixed with cumin and milk can be taken for insomnia.

• DOSAGE: powder- 2-4gm;paste- 10-20gm per day.

ARTEMISIA VULGARIS• Also known as Mugwort, Common

Wormwood. • BIOLOGICAL SOURCE:leaves and

flowering tops of the plant Artemisia vulgaris.

• FAMILY: Asteraceae • CHEMICAL CONSTITUENTS: The

important chemical constituents of mug wort are thujone,cineole,a volatile oil, acrid resin and tannin. It also cantains flavonoids,triterpenes and coumarin derivatives

USES:•  It is recommended for people with

memory deficiency due to cerebral circulation problems.

• This is an excellent brain tonic,useful in cerebral congestion and spinal cord stimulation because that the connection between brain and the spinal cord is so tight, that herbs which have effect on the spinal cord have great chances to influence a region of the brain.

• It is also prescribed for nervous and spasmodic diseases connected with debility and epilepsy.Also used for insomnia and nervousness.

Dosage:

• Tea or tincture twice daily to enhance your psychic abilities.

• One teaspoon per cup for infusion;5 – 20 drops tincture. 

FORMULATION OF BRAIN TONIC: • DRUG PREPARATION: Centella asiatica

leaves (2 1/2 tbsp),Piper longum fruits (1 tbsp),Zingiber officinale rhizome (1 tbsp),Withania somnifera root (1tbsp), Achyranthes aspera whole plant (2 1/2 tbsp),Glycyrrhiza glabra root (1 tbsp) and Terminalia chebula fruit (2 1/2 tbsp).

• DOSAGE: One teaspoonful powder is given to the patient,twice daily with milk or water

CONCLUSION• Ayurveda claims at not only increasing the

powers of the brain but also at keeping the mental diseases away, along with helping to cure them desirably.

• These ayurvedic herbs have an Antioxidant activity and thus improve the function of the brain cells and capacity to recall.

• Hence these braintonics are very low in cost and are quite safe for all ages, also during pregnancy and nursing.

• And all the herbs ayurveda uses for its brain tonics have minimum side-effects compared to synthetic medicines.

THANK YOU

ANY QUERIES ?