successful introduction of continuous renal replacement therapy

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  • 8/2/2019 Successful Introduction of Continuous Renal Replacement Therapy

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    1 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    SUCCESSFUL INTRODUCTION OF CONTINUOUS RENAL REPLACEMENT THERAPY

    (CRRT) AT THE KOMFO-ANOKYE ACCIDENT AND EMERGENCY (A&E) CENTRE

    INTRODUCTION

    The planning of the A/E Centre at KATH included the provision of two (2) CRRT

    systems at the Intensive Care Unit (ICU). However, the systems have been

    standing idle since commissioning of the Centre.

    On Thursday 15th

    of March 2012 a patient, with acute chronic renal failure was

    successfully treated on one of the machines by a team of doctors and nurses from

    the A/E Intensive Care Unit supported by two experienced nurses from the Renal

    Dialysis Unit of the Hospital, the Nephrologist at the Department of Medicine of

    KATH and a Biomedical Engineer from MEDIWISE International Company Limted.

    This successful outcome has been the result of various application training

    programs on the new technology for the personnel of the hospital by MEDIWISE

    and the provision of seed consumable by GERTECH. As a consequence to this

    successful outcome the CEO of the Hospital has decided to place an order for

    more consumable to support the beneficial use of the systems on patients.

    BACKGROUND

    CRRT equipment allows the treatment of a patients blood outside the body

    (Extracorporeal Treatment). The primary use of this system is in the Intensive

    Care setting where a sick patient on a ventilator and/ or invasive monitoring of

    vital signs requires removal of metabolic waste or accumulated fluids from the

    body as a result of renal insufficiency. In such situations, conventional practice

    has been the transfer of such patients to the Renal Dialysis Unit. Experience has

    shown, however, that the transfer and handling of such patients for Dialysis

    outside the Intensive Care Unit is froth with difficulties and complications with

    very high mortality rate.

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    2 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    CRRT allows this treatment to be bought to the patients bedside without the

    patient being moved at all. The potential benefit of this primary use of CRRT is

    life- saving for critically ill patients with hemodynamic instability. These may

    include;

    1. Post traumatic renal shut down secondary to severe blood loss2. Perinatal blood loss leading to renal failure3. Eclamptic- induced renal shut down4. Patients with accumulated fluids (pulmonary edema, cardiac tamponard,

    etc.) with poor response to diuretics

    The Secondary use of CRRT involves the removal to harmful substances from the

    blood. This non renal use includes but not limited to the following;

    1. Removal of products of infection (Cytokines) from the septicemia patientleading to rapid recovery.

    2. Removal of drugs as a result of overdose or abuse from the blood.3. Removal of snake poison from the blood. (This is very common practice in

    India)

    4. Replacement of the total plasma (blood without the cells) in a patientThere is a third important use of this system and it involves the intermittenttreatment of patients with Chronic Renal Failure. In this treatment mode waste

    removal from the blood is one step better than standard dialysis since the process

    involves both diffusion (dialysis) and convection (filtration). It is worth noting that

    CRRT system does not require a water treatment plant like the standard dialysis

    system but uses available sterile solutions.

    The Ghana Situation

    In the country CRRT is currently available only at the KATH and the 37 MilitaryHospitals thanks, to Dr Nsiah Asare (former KATH CEO) and DR Graham (Intensive

    Care Consultant, 37 Military Hospital) who, respectively, were instrumental in the

    introduction of the technology into the country under the GERTECH projects for

    the two hospitals. In both places the medical staff is just about actually putting

    the machine on a patient due to time required for various application training

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    3 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    programs, in-country technical capacity building and delays in consumable

    ordering from the manufacturer. In this respect KATH has taken the lead as the

    first Hospital in Ghana to put the equipment to use.

    It is worth noting here that B.Braun, the manufacturer of the equipment does nothonor orders for consumable supply until technical and application training have

    been carried out to safeguard the safe use of the equipment on patients. In this

    respect MEDIWISE has, with the support of B. Braun and through GERTECH, built

    this essential capacity and this was brought to bear on the successful use of the

    equipment by KATH.

    It is recommended therefore that the Ministry of Health (MOH) should avail itself

    of this capacity to introduce the technology to all tertiary and secondary level

    facilities in the country to enhance health care delivery.

    Below are pictures of this success story.

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    4 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    1. Initial Training of KATH staff at MEDIWISE Training Centre (January 2011)

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    5 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    2. More Training of KATH personnel at MEDIWISE training Centre (January 2011)

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    6 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    3. Training of ICU staff at KATH A&E Centre (March 2012)

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    7 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    4. Training of ICU & Renal Dialysis Staff at KATH A&E Centre (March 2011)

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    8 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    4. The Two CRRT machines Ready for use on Patients (March 2011)

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    9 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    5. First Patient Connected to the CRRT Machine at KATH ICU (March 2012)

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    10 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    5. KATH ICU Nurse recording Patient Parameters on CRRT (March 2012)

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    11 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    6. CEO of KATH witnessing Patient under CRRT treatment (March 2012)

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    12 | Prepared by Dr. P.R. Asman. CEO MEDIWISE.

    7. Metabolic Waste Removed from Patient after CRRT treatment (March 2012)