strontium citrate / 813-97-8 / bone health
TRANSCRIPT
Strontium Citrate
What Is It
• Strontium is a trace element found in seawater and soil. The main dietary source of strontium is seafood. Foods with lesser amounts of strontium include whole milk, wheat bran, meat, poultry, and root vegetables.
• Strontium is chemically similar to calcium. It appears to play a role in the formation of new bone while slowing the breakdown of old bone, and thus may influence bone density. There is some evidence that women with osteoporosis may not absorb strontium as they should.
Chemical Profile
• CAS#: 813-97-8• Molecular Weight: 640.86• Molecular Formula: (C6H5O7)2Sr3• Other Names: Strontium 2-hydroxy-1,2,3-
propanetricarboxylate; Tristrontium dicitrate
Strontium Increases Bone Mass Density
Strontium supplementation has been demonstrated to be a well-tolerated and effective means of preventing bone loss. In 2004, a double-blinded, placebo controlled study published in The New England Journal of Medicine aimed to evaluate the efficacy of strontium on helping to prevent structural damage and bone fragility. Over a three- year period, strontium supplementation reduced the risk of fracture by 41%. This reduction in risk was closely tied to the increase in bone mineral density in the lumbar spine and femoral neck (Fig 1). The occurrence of adverse side effects was low and reported equally among the treatment and placebo groups, further indicating the safe use of daily strontium supplements.
More About Strontium
• AbsorptionThe French pharmaceutical company Servier found that the bioavailability of strontium ranelate is about 25% (range 19-27%) after an oral dose of 2 g. The American company Osteologix claims to have superior absorption with its product strontium malonate.
• Bone QualityStrontium assists with the development of high quality bone tissue. Research found that strontium treatment increased bone mass, bone dimension, microarchitecture and intrinsic bone tissue quality.
• Long-Term EffectsA 2009 study in Denmark found that there was significant retention of strontium after treatment was completed... especially if a person had taken strontium for eight years. It concluded its findings as follows: "According to the power function model the skeletal retention three and six months after stopping the treatment would average 66% and 58%, respectively after three years of treatment, and 76% and 70%, respectively after eight years of treatment. However, individual predictions are uncertain due to large inter-individual variations, and the values cannot be extrapolated to other bone sites."
Safety & Precautions
When taken in recommended doses, strontium supplements appear to be safe. Aside from occasional mild gastrointestinal upset, includingdiarrhea, side effects are rare. However, excessive doses of strontium may replace too much calcium in the bone and hurt vitamin Dmetabolism, causing them to weaken.
WARNING: Do not take this product if you have a renal disorder or if you are pregnant or nursing. Do not exceed recommended dosage.
In the USA and Canada strontium citrate is available as a dietary supplement....
Research by pharmaceutical companies has shown that
strontium can improve bone density by 8-14% when combined with daily supplements of 1,500 mg of calcium and 800 IUs of vitamin D
Where To Buy Strontium Citrate
Wuxi Cima Science Co., Ltd.
A Chinese and creative company, dedicated to developing, manufacturing and marketing innovative botanical active ingredients, nutritional raw materials for the food, beverage nutraceutical, pharmaceutical, cosmetic and feed industries.• stable and large production capacity• in house lab testing• comprehensive files system• rich experience since 2003• top-class service
Strontium Citrate3#.Building, No. 288 Shibawan Road Wuxi 214064 Jiangsu China
Wuxi Cima Science Co., Ltd. / www.cimasci.com / [email protected] / +86 510 85518225