Storing your baby’s stem cellsInsception Lifebank - Canada's largest and most experienced cord blood and tissue bank

There is only one opportunity to store

your baby's cord blood and tissue

stem cells - at birth.

What is cord blood?

Cord blood is the blood that remains in your baby’s umbilical cord and placenta. Cord blood is a rich source of blood stem cells and other important cells.

Cord tissue is a segment of the baby’s umbilical cord. Cord tissue is a rich source of mesenchymal stem cells (MSCs), which are the precursors to bone, cartilage, muscle and fat tissues.

Stem cells are powerful because they have the ability to create and regenerate the organs, blood, tissue and the immune system that make up our bodies.Stem cells can be found in bone marrow and fat tissue. However, younger, more flexible stem cells come from a newborn’s umbilical cord blood and tissue. As an important source of such potent stem cells, umbilical cord blood and tissue can be stored for potential future use.

Why are stem cells powerful?

What is cord tissue?

Cord blood and tissue basics

1. Enroll

Learn about your cord blood and tissue banking

options and enroll online.

2. Receive Your Kit

Receive your collection kit. Store at room temperature.

Bring it with you to your birthing

facility.

3. Collection

After your baby is born, cord blood and tissue are collected by your OBGYN

or midwife. Call Insception Lifebank within 2 hours of the birth for pick-up

of stem cells.

4. Processing & Storage

Insception Lifebank sends an SMS to confirm receipt of your sample. Cord blood

and tissue is processed and the baby’s stem cells

are safely and securely stored for the future.

Cord blood & cord tissue are rich in powerful stem cells that can only be collected at birth for potential future use.

Stem cells can be used now for medical treatments and new therapies are being researched for potential future uses of cord blood and tissue, for conditions including type-1 diabetes, cerebral palsy and autism.

Your baby’s cord blood stem cells are a perfect match for your child and may be a match for siblings.

Store with Insception Lifebank, Canada's largest and most experienced cord blood and tissue bank. Today, parents of more than 75,000 babies have stored with us.

Insception Lifebank is a trusted partner of key hospitals:

What is the banking process?

Overview:Storing your baby's stem cells

Make an informed decision

by visiting insception.com/

learn

What can cord blood treat today?

Today, cord blood stem cells have been used in the treatment of over 80 life threatening diseases. 1 There have been over 40,000 transplants2 worldwide using cord blood in place of bone marrow for conditions including:

• Solid tumors • Immune deficiencies • Cancers • Blood disorders & leukemias • Genetic diseases

What are the emerging treatments where cord blood may be used?

Scientific research is evaluating how cord blood cells may provide new therapies for a broad number of diseases for which there is no effective treatment today. While regenerative medicine has exciting potential, its prospects remain dependent on the success of ongoing research around the world. Conditions with clinical trials ongoing:3

• Autism • Cerebral Palsy • Type-1 Diabetes • Stroke

Importantly, a number of the new cord blood cell therapies being researched anticipate requiring cells directly from the patient being treated (i.e. autologous therapies).

Can cord blood be used for siblings?Cord blood has a greater potential to be a match for siblings compared to unrelated donors. Sibling cord blood has been associated with better clinical outcomes and fewer possible complications that may be associated with a third party donor.4

80+ diseases treated1

visit insception.com/learn

Why store cord blood and tissue?Why store cord tissue?

Research suggests that mesenchymal stem cells (MSCs) have the ability to develop into structural and connective tissue. This important characteristic means that they could potentially be used to treat more conditions than cord blood alone can treat.5

Today, there are 70+ ongoing trials that are investigating the potential of MSCs to help treat a variety of medical conditions including:3

• Stroke • Multiple Sclerosis • Rheumatoid Arthritis • Wound Repair

Storing cord tissue today may provide future health options for your child and your family.

Emerging cord blood technologies

Advancements in technology may enable the number of cells available from cord blood collections to be expanded.

The important benefits of cell expansion would be: 6

• Extending the period over which cord blood stem cells may be used, as treatments for adults require more stem cells than treatments for a child

• Increasing the potential number of therapies from one unit of cord blood

Cerebral Palsy Sibling Cord Blood Collection Program

Insception Lifebank offers free cord blood collection and storage for children who have siblings with

cerebral palsy. The program aims to ensure as many families as possible

have access to potential local or international cord blood trials

and treatments.

For more information call 1 866 606 2790

Over

50% of parents store

cord tissue7

Save up to $250* when you order

Generation NIPT and cord blood &

tissue storage

TM

> Begin your pregnancy health care journey with Generation NIPT. Then stay at the forefront of medical science by storing your baby’s cord blood and tissue stem cells.

> Generation screens for: • Trisomy 21

– Down syndrome• Trisomy 18

– Edward’s syndrome • Trisomy 13

– Patau syndrome • Sex chromosome

abnormalities • Gender identification• Additional genetic

screening available

Generation NIPT plus

Cord Blood Banking

Begin your pregnancy health care journey with Panorama Prenatal Screen, a non-invasive DNA screening that lets you know more about your baby’s health.

Then stay at the forefront of medical science by storing your baby’s cord blood and tissue stem cells with Insception Lifebank.

Panorama™ Prenatal ScreenPLUSCord BloodBanking

Savewhen you order

Panorama Prenatal Screen and

cord blood &tissue storage

TM

How does it work?

≥ 9 WEEKS 34+ WEEKS

Order Panorama Receive results Receive cord blood and tissue storage rebate voucher

Order cord blood and tissue storage with Insception Lifebank

Redeem rebate voucher for one year free storage

Panorama Chromosome conditions tested: Trisomy 21 Trisomy 18 Trisomy 13 Triploidy Monosomy X Sex-chromosome aneuplodies Microdeletions Fetal sex

Timing: The Panorama non-invasive prenatal test (NIPT) can be done as early as 9 weeks gestation.

Why Insception Lifebank?

Experience

Clinical Trial Investments Customer Service

Access to Health Care ProfessionalsAccreditation

As Canada’s largest and most experienced cord blood bank, we are committed to delivering balanced, scientific, evidence based information to both health care professionals and Canadian families.

FDAregistered

With over 20 years of experience, Insception Lifebank has processed and stored over 75,000 cord blood units:• We have released more cord blood

units for treatments and clinical trials than all other private Canadian providers combined

Insception Lifebank is committed to providing convenient and reliable customer service:• Our service is available at ALL

Canadian hospitals and home births with worry-free bedside pickup

The Insception Lifebank/Cell Care Group is actively investing in cord blood clinical trials and research for diseases including:• Cerebral Palsy• Type-1 Diabetes

Current and prospective clients have access to our health care professional resources:• Medical Director Dr. Robert Casper

and Scientific Advisor Dr. Ian Rogers have extensive research experience in cell based therapies

Insception Lifebank is fully licensed for the collection, processing and storage of umbilical cord blood and has achieved highest level of Voluntary Accreditation

Partnerships

Insception Lifebank is a trusted partner with key hospitals:• Insception Lifebank works with more

obstetricians at more hospitals

For more information call 1 866 606 2790 or visit insception.com/panorama

Offer subject to change without notice.

Terms and conditions: 12 month payment options include a one-time $95 administration fee. Annual storage plan fees are adjusted each year, on the 1st of July, to align with the national consumer price index (CPI) as reported by Statistics Canada. All prices are subject to change. For the most recent prices, refer to www.insception.com. Prices displayed are rounded down to the nearest dollar. Prices do not include promotional or repeat client discounts. Applicable taxes and medical courier costs are not included. Some birthing facilities may charge an additional fee for cord blood and tissue collection. A credit card fee of 1% will be applied to the total amount payable before taxes. Please refer to client storage agreement for full terms and conditions.

* Terms and conditions apply, for more information visit insception.com/refer-friend

Pricing & Payment Options

Referred by a friend? You and your friend can both receive a voucher of up to

$125* when you enroll

Insception Lifebank offers a number of flexible cord blood and tissue options to meet your family’s individual needs.

Annual Storage Plans

• Include an initial fee for the collection kit, processing and testing of the cord blood and tissue

• This initial fee can be paid over 12 months or as one payment• A yearly storage fee is payable without commitment to a specific timeframe

Prices starting from

Prepaid Storage Plans are also availableFor full pricing details, visit insception.com

References:1. Karen K. Ballen et al. Umbilical cord blood transplantation: the first 25 years and beyond. Blood. July 25, 2013 vol. 122 no. 4 491-498.2. Update on umbilical cord blood transplantation, Ballen K, (2017) https://www.ncbi.nlm.nih.gov/pubmed/289289573. https://clinicaltrials.gov/4. Bizzetto et al, haematologica | 2011; 96(1): 1345. Omar et al, Umbilical Cord Mesenchymal Stem Cells: The New Gold Standard for Mesenchymal Stem Cell-Based Therapies? Tissue Eng Part B Rev. April 2014 (Epub ahead of print). 6. Nietfeld JJ, Pasquini MC, Logan BR,Verter F, Horowitz MM. Lifetime probabilities of hematopoietic stem cell transplantation in the US. Biol Blood Marrow transplant. Mar 2008; 14(3): 316-3 7. Insception data on file. Rolling 6 months, Cord Tissue % of total storage.

© 2018 Insception Biosciences Inc. All Rights Reserved.Subject to change without notice. V03-EN8PG2018 - Oct. 1, 2018

+ +

Initial fee

OR

Storage Fee

Cord Blood Cord Blood & Cord Tissue

$125 per year

$235 per year

$1080OR

$97 per month

for 12 months

$1700OR

$149 per month

for 12 months