Additional ReferencesAdditional References

_ Dr Christiane Northrup, “ Women’s Dr Christiane Northrup, “ Women’s Bodies, Women’s Wisdom”, Revised Bodies, Women’s Wisdom”, Revised 1998, Bantam, NY, NY, mainly pp 1998, Bantam, NY, NY, mainly pp 392-407. (Some information 392-407. (Some information onon Natural Family Planning, NFP)Natural Family Planning, NFP)

_ Katherine Davis, Katherine Davis, SelfSelf, Dec 2000, , Dec 2000, p.82 (more info on NFP)p.82 (more info on NFP)

_ Jackie Jackie CissellCissell_ JoelJoelBrind Brind

Additional ReferencesAdditional References

_ Seaman, Barbara, “The Seaman, Barbara, “The Doctor’s Case Against the Pill”, Doctor’s Case Against the Pill”, Doubleday-Dolphin, Garden Doubleday-Dolphin, Garden City, New York, 1980.City, New York, 1980.

_ This book is on 2 hour reserve This book is on 2 hour reserve for Chem. 100 in Milne. for Chem. 100 in Milne.

STEROID STRUCTURAL STEROID STRUCTURAL CHARACTERISTICS:CHARACTERISTICS:

Structure is based on the ring Structure is based on the ring structure below:structure below:

SMALL STRUCTURAL DIFFERENCES SMALL STRUCTURAL DIFFERENCES HAVE PROFOUND CONSEQUENCESHAVE PROFOUND CONSEQUENCES

Estradiol Testosterone

ANDROGENSANDROGENS-1-1

•Produce secondary sex characteristics of males.•Used For:•Muscle Building•Testosterone Replacement

•Following information from Bruce Bower, Sci. News, 13 Jul ‘89, pp30,31.

Blood ClottingBlood Clotting Testicular AtrophyTesticular Atrophy Difficulty in urinating Difficulty in urinating Male Pattern BaldingMale Pattern Balding Decreased Sperm ProductionDecreased Sperm Production ImpotenceImpotence HypertensionHypertension

SIDE EFFECTS/ MEN / SIDE EFFECTS/ MEN / ANDROGENSANDROGENS #2:

SIDE EFFECTS / MEN / ANDROGENS#3:SIDE EFFECTS / MEN / ANDROGENS#3:

Insulin ResistanceInsulin Resistance Inability to EjaculateInability to Ejaculate High CholesterolHigh Cholesterol Fluid RetentionFluid Retention Heart AttackHeart Attack Risk of Kidney Disease IncreasedRisk of Kidney Disease Increased Mental Disorders (Roid Rage)Mental Disorders (Roid Rage)

ANDROGEN SIDE EFFECTS / WOMENANDROGEN SIDE EFFECTS / WOMEN

Enlargement of Clitoris(1)Enlargement of Clitoris(1) Loss of Body CurvesLoss of Body Curves Deepening of VoiceDeepening of Voice Menstrual ProblemsMenstrual Problems Irreversible Pattern BaldnessIrreversible Pattern Baldness

(1)See Dayton, L., Women’s Sports and Fitness, Mar. ‘90, pp 52-55.

ESTROGENS, PROGESTINS- BIRTH ESTROGENS, PROGESTINS- BIRTH CONTROL PILLSCONTROL PILLS

Can control male as well as female Can control male as well as female fertility- dropped as male pillfertility- dropped as male pill

Use as male pill dropped when one Use as male pill dropped when one man was found to have testicular man was found to have testicular atrophy*atrophy*

Three women died- the formula was Three women died- the formula was changed and the tests proceeded!!*changed and the tests proceeded!!*

In women, the pill simulates In women, the pill simulates pregnancypregnancy

*From *From Dr Ellen GrantDr Ellen Grant “The Bitter Pill” “The Bitter Pill”

PillPill

_ “ “ According to the Western model, According to the Western model, pregnancy is a disease, menopause is a pregnancy is a disease, menopause is a disease, and even not getting pregnant disease, and even not getting pregnant is a disease. Dangerous drugs and is a disease. Dangerous drugs and devices are given to women, but not to devices are given to women, but not to men-just for birth control. I’ve reached men-just for birth control. I’ve reached the conclusion that to many doctors the conclusion that to many doctors being a woman is a disease.” (being a woman is a disease.” (Italics are Italics are the author’s)the author’s)

_ P. xi, Seaman, B, (see references)P. xi, Seaman, B, (see references)

..

_ ..

PILLPILL_ The modern pill has a combination The modern pill has a combination

of synthetic estrogen and progestin. of synthetic estrogen and progestin. _ In combination these drugs In combination these drugs

influence the pituitary gland in such influence the pituitary gland in such a way as to prevent ovulation and a way as to prevent ovulation and therefore fertility. therefore fertility.

_ There are slight variations in There are slight variations in administration and effect, but the administration and effect, but the drugs all chemically induce sterility.drugs all chemically induce sterility.

PROBLEMS WITH THE PILLPROBLEMS WITH THE PILL ““Minor” include: weight gain, nausea, Minor” include: weight gain, nausea,

allergic rash, dizziness, headache, facial allergic rash, dizziness, headache, facial skin pigment change, problems w/contact skin pigment change, problems w/contact lenses, aggravation of varicose veins, lenses, aggravation of varicose veins, mental depression, irregular menstrual mental depression, irregular menstrual flow*.flow*.

““Major” include: blood clots, Major” include: blood clots, thromboembolism, zinc deficiency, thromboembolism, zinc deficiency, possible cancer (esp. teens), hypertension, possible cancer (esp. teens), hypertension, increase of blood cholesterol, poor increase of blood cholesterol, poor glucose tolerance, vit. B6 deficiency, glucose tolerance, vit. B6 deficiency, bleeding liver tumors (rare)*. bleeding liver tumors (rare)*. **Dr Ellen Grant, “Sexual Dr Ellen Grant, “Sexual

Chemistry”Chemistry”

ESTROGEN THE VILLAIN?ESTROGEN THE VILLAIN? Estrogen clearly causes cancer of the Estrogen clearly causes cancer of the

reproductive tract in animals; difficult to reproductive tract in animals; difficult to prove in humans.prove in humans.

Perhaps also skin and breast cancerPerhaps also skin and breast cancer Blood clotting/ approx. 1 in 2000 women Blood clotting/ approx. 1 in 2000 women

hospitalized each year; pill users twice as hospitalized each year; pill users twice as likely to have a stroke as non-users.likely to have a stroke as non-users.

Not recommended for use with these Not recommended for use with these conditions: suspected pregnancy, history of conditions: suspected pregnancy, history of heart problems, irregular periods, diabetes, heart problems, irregular periods, diabetes, hypertension, high cholesterol, smoking.hypertension, high cholesterol, smoking.

ESTROGEN/ ESTROGEN/ WARNING:KNOWN WARNING:KNOWN

CARCINOGENCARCINOGEN_ From Science News, 25 Jan. ‘03 From Science News, 25 Jan. ‘03

vol. 163 p. 62:vol. 163 p. 62:_ Sex hormones known as steroidal Sex hormones known as steroidal

estrogens recognized as estrogens recognized as carcinogens by Nat’l Inst. Health. carcinogens by Nat’l Inst. Health. These include those used in birth These include those used in birth control pills and hormone control pills and hormone replacement therapy.replacement therapy.

ESTROGEN/ ESTROGEN/ WARNING:KNOWN WARNING:KNOWN

CARCINOGENCARCINOGEN

_ Listed earlier as probable Listed earlier as probable carcinogens now ALL carcinogens now ALL hormones of this class hormones of this class (steroidal estrogens) as of 11 (steroidal estrogens) as of 11 Dec. ‘02 are now listed as Dec. ‘02 are now listed as carcinogens.*carcinogens.*

_ *cancer causing chemical*cancer causing chemical

Estrogen is a Estrogen is a Carcinogen!Carcinogen!

_ Estrogens that are used in Estrogens that are used in hormone replacement therapy and hormone replacement therapy and birth control pills are carcinogens.birth control pills are carcinogens.

_ The National Institutes of Health The National Institutes of Health deemed on 11 Dec 2002 that ALL deemed on 11 Dec 2002 that ALL hormones in this class are moved hormones in this class are moved from probable carcinogens be from probable carcinogens be classified as carcinogens.* * classified as carcinogens.* * Sci. Sci. News, 163, p.62, Jan 25 2003News, 163, p.62, Jan 25 2003

ESTROGEN/ ESTROGEN/ WARNING:KNOWN WARNING:KNOWN

CARCINOGENCARCINOGEN_ Unless you take these pills for a Unless you take these pills for a

legitimate illness or condition STOP legitimate illness or condition STOP NOW! Being fertile is healthy- used NOW! Being fertile is healthy- used exclusively as a birth control method exclusively as a birth control method is placing yourself at risk for cancer!is placing yourself at risk for cancer!

_ Doctors or others who prescribe these Doctors or others who prescribe these estrogens simply as birth control estrogens simply as birth control might be sued for malpractice. might be sued for malpractice.

Progestogens and Progestogens and CancerCancer

_ Dr Ellen Grant in a recent letter Dr Ellen Grant in a recent letter to GP (21 Jan ‘02, p. 23) to GP (21 Jan ‘02, p. 23) references an article by Mike references an article by Mike Dixon in the British Med., J. Dixon in the British Med., J. that gives convincing evidence that gives convincing evidence of a cancer progesterone link.of a cancer progesterone link.

_ Grant cites studies that show Grant cites studies that show huge increases in breast cancer.huge increases in breast cancer.

Progestogens and Progestogens and CancerCancer_ Grant’s letter cites clear evidence Grant’s letter cites clear evidence

that both estrogen and that both estrogen and progestogens cause breast cancer progestogens cause breast cancer with figures such as 24% increases with figures such as 24% increases in women 50-54 and 42% in women in women 50-54 and 42% in women under 30. under 30.

_ She states that numerous studies She states that numerous studies have found that increases in breast, have found that increases in breast, cervical, lung and liver cancers are cervical, lung and liver cancers are associated with hormonesassociated with hormones..

Norplant & Norplant & DepoproveraDepoprovera_ Both of these are progestogins Both of these are progestogins

(progesterones). Both require (progesterones). Both require some form of hypodermic some form of hypodermic application. They are long lasting application. They are long lasting (months). These can cause (months). These can cause severe mood changes in many severe mood changes in many women as well as acting as birth women as well as acting as birth controlcontrol.. Because of mood alteration one doctor Because of mood alteration one doctor quoted in Grant’s “Sexual Chemistry” has stated that quoted in Grant’s “Sexual Chemistry” has stated that many women are so ornery when on these drugs that many women are so ornery when on these drugs that

no one would get close enough to have childrenno one would get close enough to have children. .

New Addition / New Addition / Progestogen Based Progestogen Based Birth Control Birth Control _ Levonorgestrol as a vaginal Levonorgestrol as a vaginal

suppository has recently entered suppository has recently entered the market in the U.S.the market in the U.S.

_ The trade name for this drug is The trade name for this drug is _ The drug is heavily advertised as The drug is heavily advertised as

the answer to a mother’s dream- in the answer to a mother’s dream- in her busy day she may forget the her busy day she may forget the pill. With this magic pill she can pill. With this magic pill she can hop into bed anytime.hop into bed anytime.

The Auschwitz The Auschwitz ConnectionConnection

This following information This following information comes from Dr. Ellen Grant’s comes from Dr. Ellen Grant’s book entitled “Sexual book entitled “Sexual Chemistry”Chemistry”

Female prisoners who survived Female prisoners who survived Auschwitz have an above Auschwitz have an above average number of low average number of low intelligence offspring. intelligence offspring.

Auschwitz Con’tAuschwitz Con’t

Women seem to remember treated Women seem to remember treated “soup” They lost their period within “soup” They lost their period within 10 days. 10 days.

At Nuremberg trials after the second At Nuremberg trials after the second world war- Nazis involved with world war- Nazis involved with Auschwitz testified to growing Auschwitz testified to growing S.American plants in greenhouses. S.American plants in greenhouses. These plants produce estrogen like These plants produce estrogen like substances. These chemicals form substances. These chemicals form the basis of the original “pill”.the basis of the original “pill”.

Auschwitz con’tAuschwitz con’t

Conclusion was: the women and men were fed Conclusion was: the women and men were fed estrogens as an experiment in birth control. estrogens as an experiment in birth control.

In the 1940s Margaret Sanger convinced In the 1940s Margaret Sanger convinced Katherine McCormick to fund the research for Katherine McCormick to fund the research for the “pill”. Sanger reasoned that the pill was the “pill”. Sanger reasoned that the pill was needed for the ignorant masses in jungles, needed for the ignorant masses in jungles, slums, etc. (This statement is in the slums, etc. (This statement is in the Nov/Dec/’95 issue of “The Sciences”- see slide Nov/Dec/’95 issue of “The Sciences”- see slide #1). Sanger was a leading proponent of the #1). Sanger was a leading proponent of the eugenics movement. Her motto was eugenics movement. Her motto was “more more children from the fit, less from the unfit-that is children from the fit, less from the unfit-that is the chief aim of birth control”the chief aim of birth control”

PillPill The original reason for The original reason for

development of the pill was not development of the pill was not primarily to free women, it was to primarily to free women, it was to rid the world of “undesirables” -the rid the world of “undesirables” -the dream of the moneyed elite and dream of the moneyed elite and (based on the Auschwitz evidence) (based on the Auschwitz evidence) the Nazis. the Nazis.

The The New ScientistNew Scientist points out that points out that the World Bank calls population the World Bank calls population control “the most cost effective control “the most cost effective form of development aid” form of development aid” D. D. Mackenzie,Mackenzie,New ScientistNew Scientist, 138, 3 Apr ‘90, p.4, 138, 3 Apr ‘90, p.4

PillPill It is well known that use of It is well known that use of

hormones can be detrimental to hormones can be detrimental to children if used too close to children if used too close to pregnancy. Women get pregnant- pregnancy. Women get pregnant- therefore to protect the next therefore to protect the next generation, women should not generation, women should not take chances with the pill.take chances with the pill.

This is the impetus behind the This is the impetus behind the desire for a male pill. desire for a male pill.

PillPill It is for these reasons that I agree with some “radical” It is for these reasons that I agree with some “radical”

feminists who declare the pill to be antiwoman.(For feminists who declare the pill to be antiwoman.(For Example- see Denfield, R. p.249 in Gross, P. et.al. “The Example- see Denfield, R. p.249 in Gross, P. et.al. “The Flight from Science & Reason”, NY Acad. of Sci., 1996 & Flight from Science & Reason”, NY Acad. of Sci., 1996 & Robyn Roland in “Man-Made Women”, isbn# 0-253-20450-Robyn Roland in “Man-Made Women”, isbn# 0-253-20450-x, p.86)x, p.86)

What is the alternative? Perhaps a partial answer What is the alternative? Perhaps a partial answer is in the British Medical Journal(18 Sep ‘93, is in the British Medical Journal(18 Sep ‘93, p.307). p.307).

Newer self administered tests that determine a Newer self administered tests that determine a woman’s readiness to become pregnant do work woman’s readiness to become pregnant do work as well as the pill in preventing untimely as well as the pill in preventing untimely pregnancy. pregnancy.

The benefits are a. no unnatural chemicals and b. The benefits are a. no unnatural chemicals and b. an almost non-existent divorce rate among an almost non-existent divorce rate among couples using this method. couples using this method. See “Healh”, jan/feb, ‘01, p54 for the effects See “Healh”, jan/feb, ‘01, p54 for the effects of divorce on kids.of divorce on kids.

““Natural” (Chemical-Natural” (Chemical-Free) Family PlanningFree) Family Planning

_ Natural family planning also is Natural family planning also is hormone based. hormone based.

_ Because so many couples are Because so many couples are unable to have children, methods unable to have children, methods have been developed to pinpoint have been developed to pinpoint ovulation by observing the mix of ovulation by observing the mix of hormones naturally produced by hormones naturally produced by a woman over her period. a woman over her period.

Natural” (Chemical-Natural” (Chemical-Free) Family PlanningFree) Family Planning

_ Very precise timing of ovulation is Very precise timing of ovulation is possible. possible.

_ Carl Djerassi, an early investigator in Carl Djerassi, an early investigator in pill research has been quoted as being pill research has been quoted as being in favor of fertility monitoring for in favor of fertility monitoring for teens and young women- both for birth teens and young women- both for birth control(NFP) and for fertility. He says control(NFP) and for fertility. He says there are red light and green light there are red light and green light hormoneshormones. (see . (see DiscoverDiscover, Mar., ‘91, p. , Mar., ‘91, p. 23.)23.)

Natural” (Chemical-Natural” (Chemical-Free) Family PlanningFree) Family Planning

_ Couples have been able in some Couples have been able in some cases to overcome their lack of cases to overcome their lack of fertility in this way.fertility in this way.

_ The time of ovulation can be The time of ovulation can be precisely timed and this knowledge precisely timed and this knowledge is helpful.is helpful.

_ Additionally, precise knowledge of Additionally, precise knowledge of a woman’s cycle helps doctors to a woman’s cycle helps doctors to diagnose problems.diagnose problems.

CHEMICAL FREE FAMILY CHEMICAL FREE FAMILY PLANNINGPLANNING

_ There are three methods- There are three methods- – Monitor hormonesMonitor hormones– Monitor temperatureMonitor temperature– Monitor mucusMonitor mucus

_ One or all of these methods work One or all of these methods work either for determining the either for determining the optimum time to become pregnant optimum time to become pregnant or not pregnant. The partners can or not pregnant. The partners can then make decisions on this basis. then make decisions on this basis.

PILLPILL

_ There are no side effects, no There are no side effects, no hormone induced or fed cancer, no hormone induced or fed cancer, no cardiovascular damage, no Zn cardiovascular damage, no Zn depletion or other hormone induced depletion or other hormone induced syndromes.syndromes.

_ Recently a test kit has become Recently a test kit has become available in Great Britain and available in Great Britain and should be approved in the U.S. should be approved in the U.S.

SOME NEWER ITEMS SOME NEWER ITEMS /PILL/PILL

_ ““Science News” (vol 155-23/01/99-p.56) Science News” (vol 155-23/01/99-p.56) reports that only some chlorinated reports that only some chlorinated hydrocarbons, not DDT, chlordane, or hydrocarbons, not DDT, chlordane, or kepone are associated with elevated kepone are associated with elevated breast cancer risk. High blood levels of breast cancer risk. High blood levels of dieldrin, the most estrogen-like dieldrin, the most estrogen-like insecticide, is associated with double insecticide, is associated with double the cancer risk of dieldrin free womenthe cancer risk of dieldrin free women. . (One wonders about the wisdom of using (One wonders about the wisdom of using estrogens themselves when chemicals estrogens themselves when chemicals that mimic estrogens are so risky.) that mimic estrogens are so risky.)

Environmental Environmental EstrogensEstrogens

_ An article in Chemical & An article in Chemical & Engineering News (Bette Hileman, Engineering News (Bette Hileman, 31 Jan. ‘94, p.19) indicates that 31 Jan. ‘94, p.19) indicates that environmental estrogens and environmental estrogens and estrogen mimics may be causing estrogen mimics may be causing increases in breast cancer, birth increases in breast cancer, birth defects in male reproductive defects in male reproductive organs, testicular cancer, organs, testicular cancer, endometriosis and other disorders. endometriosis and other disorders.

Estrogens/Popular Estrogens/Popular PressPress

_ In the Parade section of the 31 Jan In the Parade section of the 31 Jan 99 edition of the Hartford Courant 99 edition of the Hartford Courant (CT) Dianne Hales states that the (CT) Dianne Hales states that the longer in life a woman is exposed to longer in life a woman is exposed to estrogen, the greater the risk of estrogen, the greater the risk of breast cancer (p5). She refers to breast cancer (p5). She refers to self-produced estrogen- but why not self-produced estrogen- but why not those estrogens in the pill? Are these those estrogens in the pill? Are these estrogens safer than natural ones? estrogens safer than natural ones?

SOME NEWER SOME NEWER ITEMS/PILLITEMS/PILL_ The British Medical Journal (Dec 1998) The British Medical Journal (Dec 1998)

recently reported that long term studies recently reported that long term studies indicate a lessening of risk to 0 for indicate a lessening of risk to 0 for profound side effects from the pill ten profound side effects from the pill ten years after discontinuance of use. years after discontinuance of use. However, note that the effects are there However, note that the effects are there during use and for ten years after. during use and for ten years after. Additionally, only survivors were Additionally, only survivors were counted. Those who died before the counted. Those who died before the study were not counted. CBS news used study were not counted. CBS news used the headline “Pill causes no Problems”- the headline “Pill causes no Problems”- clearly misleading. clearly misleading.

New Items/HormonesNew Items/Hormones_ TamoxifenTamoxifen is a drug antagonist for is a drug antagonist for

estrogen. It is used to reverse the estrogen. It is used to reverse the tumor promoting effects of estrogen tumor promoting effects of estrogen in treatment of breast cancer.* in treatment of breast cancer.* There have been conflicting There have been conflicting published reports of use as a tumor published reports of use as a tumor preventative. Note the clear and preventative. Note the clear and consistent connection between consistent connection between breast cancer and estrogen.breast cancer and estrogen.

_ **J Brainard, “Science News”, p.37, 18 Jul. ‘98J Brainard, “Science News”, p.37, 18 Jul. ‘98

FORMULA ADJUSTMENTS TO REDUCE FORMULA ADJUSTMENTS TO REDUCE PROFOUND SIDE EFFECTSPROFOUND SIDE EFFECTS

The major adjustment has been The major adjustment has been to reduce or eliminate estrogen.to reduce or eliminate estrogen.

The “minipill” introduced with The “minipill” introduced with progestin only.progestin only.

Newer estrogens and progestins Newer estrogens and progestins tested for use in pills.tested for use in pills.

Dr Grant was in on the testing of Dr Grant was in on the testing of reduced estrogen pills and was reduced estrogen pills and was unimpressedunimpressed..

Hormone Replacement Hormone Replacement Therapy (HRT)Therapy (HRT)

_ A recent article in U.S.News and A recent article in U.S.News and World Report shows that steroid World Report shows that steroid replacement does not do what was replacement does not do what was advertised.advertised.

_ HRT does not reduce heart attack HRT does not reduce heart attack (increases occur instead), cardio-(increases occur instead), cardio-vascular problems, and vascular problems, and osteoporosis.*osteoporosis.*

_ **Spake, Amanda, US News & Wrld rpt, 21 Jan ‘02, p. 54Spake, Amanda, US News & Wrld rpt, 21 Jan ‘02, p. 54

ESTROGEN? A ESTROGEN? A PROBLEM?PROBLEM?

_ Health magazine states that a federal Health magazine states that a federal advisory panel recommended that the advisory panel recommended that the National institutes of Health recognize National institutes of Health recognize estrogen as a cancer causing substance. estrogen as a cancer causing substance. This was followed by soothing words This was followed by soothing words about risk/benefit. (P.182, Mar’01) On about risk/benefit. (P.182, Mar’01) On the same page, a new delivery of estrogen the same page, a new delivery of estrogen containing birth control chemicals (by containing birth control chemicals (by injection) was being touted. This injection) was being touted. This magazine is supposedly trying to help magazine is supposedly trying to help women. women.

Lunelle/ Monthly Lunelle/ Monthly “protection”“protection”

_ Lunelle is an injectable form of Lunelle is an injectable form of hormones: medroxyprogesterone hormones: medroxyprogesterone acetate (a progesterone) and acetate (a progesterone) and estradiol cyprionate (an estrogen) estradiol cyprionate (an estrogen)

_ The following is a statement in an The following is a statement in an advertisement for the drug. advertisement for the drug.

_ ““Serious risks that can be life Serious risks that can be life threatening include blood clots, threatening include blood clots, stroke, and heart attack” stroke, and heart attack”

Lunelle, ContinuedLunelle, Continued_ As is true with all hormonal As is true with all hormonal

birth control methods, the ad. birth control methods, the ad. states that there is states that there is no no protection from AIDS or other protection from AIDS or other sexually transmitted diseases.sexually transmitted diseases.

_ The hormones used are The hormones used are synthetic chemicals; not synthetic chemicals; not produced by a woman’s body.produced by a woman’s body.

PillPill

_ All the chemicals used in all pills need to survive All the chemicals used in all pills need to survive the gastrointestinal system. None of the steroids the gastrointestinal system. None of the steroids now used are produced naturally in the body. now used are produced naturally in the body. These natural steroids need injection. Users of These natural steroids need injection. Users of the pill cannot avoid the fact that manufactured the pill cannot avoid the fact that manufactured chemicals produce a disorder in a healthy bodychemicals produce a disorder in a healthy body.. This is identical to ingesting the pesticides, additives and This is identical to ingesting the pesticides, additives and other chemicals that can cause problems. other chemicals that can cause problems.

_ Being able to become pregnant is healthy- becoming Being able to become pregnant is healthy- becoming chemically sterile is not. The body is being stressed by chemically sterile is not. The body is being stressed by synthetic hormone-like substances when the “pill” is used synthetic hormone-like substances when the “pill” is used in an otherwise healthy person. Dr Ellen Grant went from in an otherwise healthy person. Dr Ellen Grant went from staunch advocate to opponent of steroid contraceptives staunch advocate to opponent of steroid contraceptives based on her patients’ bad experiencesbased on her patients’ bad experiences. .

Hormones/Hormone -like Hormones/Hormone -like Chemicals in the Chemicals in the

EnvironmentEnvironment _ Articles are appearing in the Articles are appearing in the

scientific journals that show ill scientific journals that show ill effects on fish from estrogens effects on fish from estrogens and estrogen mimicking and estrogen mimicking chemicals. Estradiol can affect chemicals. Estradiol can affect fish at the 1 part per trillion fish at the 1 part per trillion level.level. See for example G.Vines, “Unmanned by a See for example G.Vines, “Unmanned by a sea of Oestrogen (estrogen)”, sea of Oestrogen (estrogen)”, New ScientistNew Scientist, 138 , 138 1993 p.5 and L.C.Folmar et.al., 1993 p.5 and L.C.Folmar et.al., Environmental Environmental Health Perspectives, 104:10 Health Perspectives, 104:10 Oct ‘96, p. 1096 Oct ‘96, p. 1096

Environmental Environmental EstrogensEstrogens

_ One of the new contraceptive rings One of the new contraceptive rings can contaminate 24 million liters can contaminate 24 million liters of water in concentrations of of water in concentrations of steroids high enough to affect fish.steroids high enough to affect fish.

_ This puts this device in the same This puts this device in the same category as the contraceptive category as the contraceptive patch. * patch. *

_ *Sci News, 163, p62, Jan. 25, 2003*Sci News, 163, p62, Jan. 25, 2003

PILL /Article in PILL /Article in “Health”“Health”

_ The pill The pill doesdoes cause breast cancer cause breast cancer according to researchers at the according to researchers at the Mayo Clinic. A study of women Mayo Clinic. A study of women who used the “pill” up to 1975 who used the “pill” up to 1975 showed a showed a three times greater three times greater incidence of breast cancer over incidence of breast cancer over non-usersnon-users. The reduced estrogen . The reduced estrogen pill used post’75 theoretically was pill used post’75 theoretically was expected to be less dangerous.* expected to be less dangerous.* Care to participate as a voluntary lab subject? Take the Care to participate as a voluntary lab subject? Take the pill. You can trust them.pill. You can trust them.*Zandonella, C., *Zandonella, C., Health,Health,jan/feb, 2000, p.144jan/feb, 2000, p.144

PILL/ Evidence for PILL/ Evidence for Danger in Danger in

Second&Third Second&Third GenerationGeneration_ The evidence is reported in a The evidence is reported in a

Medlineplus article derived from a Medlineplus article derived from a report by Martha Kerr for Reuters/ report by Martha Kerr for Reuters/ 8 Feb ‘02. The risk of stroke from 8 Feb ‘02. The risk of stroke from third generation pills is twice that third generation pills is twice that for the second generation pill. for the second generation pill. Both second and third generation Both second and third generation pills are worse than the original pills are worse than the original formulations for the pill. formulations for the pill.

Recent News/HormonesRecent News/Hormones

_ Designer estrogen mimics: New Designer estrogen mimics: New developments based on tamoxifen developments based on tamoxifen and raloxifene seem to suggest that and raloxifene seem to suggest that by careful chemical design it may by careful chemical design it may be possible to reduce or eliminate be possible to reduce or eliminate side effects while retaining benefits side effects while retaining benefits of hormone replacement therapy. of hormone replacement therapy. Christensen, D., “Science News”, Christensen, D., “Science News”, 16 Oct ‘99, p252. 16 Oct ‘99, p252.

RECENT NEWS / RECENT NEWS / HormonesHormones

_ On 24 July ‘01 the Oneonta Daily On 24 July ‘01 the Oneonta Daily Star reported that the American Star reported that the American Heart Association no longer Heart Association no longer recommends that estrogen be given recommends that estrogen be given to women to help prevent heart and to women to help prevent heart and other cardio-vascular problems. It other cardio-vascular problems. It does not work although it was does not work although it was previously thought to help keep the previously thought to help keep the cardiovascular system healthy. cardiovascular system healthy.

RECENT NEWS/ RECENT NEWS/ Hormones/ZnHormones/Zn

_ Recent data indicate that Americans Recent data indicate that Americans do not get enough zinc*. Zn is do not get enough zinc*. Zn is essential for proper immune system essential for proper immune system function, wound healing, taste, function, wound healing, taste, protein pro-duction, maintaining protein pro-duction, maintaining insulin, disposal of COinsulin, disposal of CO22, sperm , sperm production, fetal development, bone production, fetal development, bone density and hun-dreds of enzymes. density and hun-dreds of enzymes. Estrogen use depletes Zn. Best Estrogen use depletes Zn. Best source is red meat.*source is red meat.*Feder, D., Better Homes & Gardens. P.122, Feder, D., Better Homes & Gardens. P.122,

Oct. 1997.Oct. 1997.

RECENT NEWS/ RECENT NEWS/ Hormones/ZnHormones/Zn

_ Adults need 12-15 mg (milligrams Adults need 12-15 mg (milligrams or .001 gram) per day. or .001 gram) per day.

_ Sources in mg/ounce: fortified Sources in mg/ounce: fortified cereal, 15^; oysters, steamed, 9; cereal, 15^; oysters, steamed, 9; beef, cooked, 2; pork, cooked, .9; beef, cooked, 2; pork, cooked, .9; nuts&peanuts^, .9; oatmeal, (not nuts&peanuts^, .9; oatmeal, (not fortified), cooked, .9; chicken, dark fortified), cooked, .9; chicken, dark meat, .75; chicken, white meat, .35. meat, .75; chicken, white meat, .35. Fish, eggs, milk, .25. ^Veg-etable Fish, eggs, milk, .25. ^Veg-etable Zn is less easily absorbed. Zn is less easily absorbed.

RU486/Prostaglandins- RU486/Prostaglandins- AbortifacientsAbortifacients

_ RU 486 acts by interfering with RU 486 acts by interfering with progesterone. It is a synthetic progesterone. It is a synthetic steroid hormone. Once again all the steroid hormone. Once again all the long term problems associated with long term problems associated with steroid use are potentially present. It steroid use are potentially present. It acts by making the lining of the acts by making the lining of the uterus inhospitable to the new uterus inhospitable to the new human being. Deprivation of human being. Deprivation of nutrients starves the baby and it nutrients starves the baby and it dies. dies.

Use of Misoprostol Use of Misoprostol (Cytotek), a Synthetic (Cytotek), a Synthetic

Prostaglandin Prostaglandin _ Once the RU486 does its job and the baby is dead, the Once the RU486 does its job and the baby is dead, the

remains must be flushed from the uterus. Typical usage remains must be flushed from the uterus. Typical usage of RU486 requires the woman (day 1) with a verified 3-9 of RU486 requires the woman (day 1) with a verified 3-9 week pregnancy to ingest RU486. After 48 hours, she week pregnancy to ingest RU486. After 48 hours, she returns to the doctor (~3% of women will have miscarried returns to the doctor (~3% of women will have miscarried the baby at this time). Women who have not yet the baby at this time). Women who have not yet miscarried then receive misoprostol to induce labor. She miscarried then receive misoprostol to induce labor. She must remain in the doctor’s care for at least 4 hours to must remain in the doctor’s care for at least 4 hours to be monitored for side effects. Another 54% of be monitored for side effects. Another 54% of miscarriages will occur at the doctors office during this 4 miscarriages will occur at the doctors office during this 4 hours. If no miscarriage occurs, the woman is released . hours. If no miscarriage occurs, the woman is released . A miscarriage may occur anywhere now. In 43% of the A miscarriage may occur anywhere now. In 43% of the cases the woman leaves the office to go into labor on her cases the woman leaves the office to go into labor on her own. Bleeding can occur and last up to 14 days. own. Bleeding can occur and last up to 14 days. (continued on the next slide) (continued on the next slide)

Cont’d from Previous Cont’d from Previous slide- Ru486/Cytotek slide- Ru486/Cytotek

abortions abortions _ The patient returns to the doctor after 14 days for a The patient returns to the doctor after 14 days for a checkup. She will then undergo a dilation & curettage checkup. She will then undergo a dilation & curettage (D&C) to remove any remains that may cause an (D&C) to remove any remains that may cause an infection. Some women (5-10%) will not have the abortion infection. Some women (5-10%) will not have the abortion and will require a surgical abortion. (NOTE: the and will require a surgical abortion. (NOTE: the percentages used will not necessarily add up to 100 due percentages used will not necessarily add up to 100 due to an uncertainty of up to 5% in many percentages given.)to an uncertainty of up to 5% in many percentages given.)

_ G.D. Searle has issued a warning to doctors about G.D. Searle has issued a warning to doctors about CytotekCytotek.. On 23 Aug. 2000, Michael Cullen, MD wrote to the On 23 Aug. 2000, Michael Cullen, MD wrote to the nation’s obstetricians about serious side effects when nation’s obstetricians about serious side effects when used off-label. The company has incomplete risk research used off-label. The company has incomplete risk research for use with RU486 or similar chemicals. The chemical is for use with RU486 or similar chemicals. The chemical is not approved by GD Searle for induction of labor or not approved by GD Searle for induction of labor or abortion. It is approved for use in preventing the bleeding abortion. It is approved for use in preventing the bleeding that occurs from NSAIDS such as aspirin and ibuprofen. that occurs from NSAIDS such as aspirin and ibuprofen. cont’d on next slidecont’d on next slide

Ru486, ContinuedRu486, Continued_ There are some uses for RU486 that are not There are some uses for RU486 that are not

connected with abortion. Among these are possible connected with abortion. Among these are possible use for breast cancer. As with all scientific use for breast cancer. As with all scientific discoveries there are wise and unwise uses. As for discoveries there are wise and unwise uses. As for Citotek, prevention of bleeding from aspirin and Citotek, prevention of bleeding from aspirin and other NSAIDS is a boon for arthritis patients and other NSAIDS is a boon for arthritis patients and others who depend on NSAIDS for pain and others who depend on NSAIDS for pain and inflammation relief. A contact with representative inflammation relief. A contact with representative Sherwood Boehlert, Represen-tative to the House led Sherwood Boehlert, Represen-tative to the House led to some information justifying the FDA’s approval of to some information justifying the FDA’s approval of Citotek. The information in the Searle letter is Citotek. The information in the Searle letter is disputed by the American College of Gynecologists disputed by the American College of Gynecologists and Obstetricians who see Cytotek as a useful drug in and Obstetricians who see Cytotek as a useful drug in their practice. their practice.

_ See an edited version of the RU-486 news in Health See an edited version of the RU-486 news in Health Magazine, jan/feb 2001, p. 147Magazine, jan/feb 2001, p. 147

RU486 ContinuedRU486 Continued

_ They see the risks listed in the Searle letter as They see the risks listed in the Searle letter as overblown and they assert that at the overblown and they assert that at the concentrations they use the risks are minimal. concentrations they use the risks are minimal. (Perhaps because it is not administered to them.) (Perhaps because it is not administered to them.) Please note that it is very unusual for a drug Please note that it is very unusual for a drug company to not maximize use of their product as company to not maximize use of their product as Searle has done .Searle has done .

_ The letter from Rep Boehlert and the information The letter from Rep Boehlert and the information sent me on cytotek is available from the instructor sent me on cytotek is available from the instructor

Natural Family Natural Family Planning (NFP)- Further Planning (NFP)- Further

InformationInformation_ Call ELIZABETH COLLINS AT Call ELIZABETH COLLINS AT

607 432 9264 OR607 432 9264 OR_ MARY KAY KENNEDY AT 607 MARY KAY KENNEDY AT 607

746 3049746 3049_ HOME STUDY: 1 800 745 8252HOME STUDY: 1 800 745 8252_ Email: ccli@ccli.orgEmail: ccli@ccli.org

ABORTION & ESTROGENABORTION & ESTROGEN

_ Dr. Joel BrindDr. Joel Brindof Baruch College of Baruch College SUNY has published some SUNY has published some research that indicates an research that indicates an increased risk of cancer after an increased risk of cancer after an induced abortion. Once again induced abortion. Once again abnormal estrogen production abnormal estrogen production or response may be at the or response may be at the bottom of this observation.bottom of this observation.

Additional Additional News/Steroid Related News/Steroid Related

_ Full term pregnancies spur Full term pregnancies spur tumor suppressor chemical tumor suppressor chemical (Sci. News, vol 160, 20 Oct ‘01, (Sci. News, vol 160, 20 Oct ‘01, p.247). Breast cancer reduced p.247). Breast cancer reduced when naturally occurring when naturally occurring steroids produced during steroids produced during pregnancy induce a cancer pregnancy induce a cancer protecting protein named p53. protecting protein named p53.

CHEM100/newer CHEM100/newer materialmaterial

_ Evidence for the embryo as an inde-Evidence for the embryo as an inde-pendent individual comes from the pendent individual comes from the discovery that the mother’s body discovery that the mother’s body rejects it as a foreign invader.rejects it as a foreign invader.

_ The reason the new embryo is not The reason the new embryo is not ex-pelled is that a hormone called ex-pelled is that a hormone called cotropin releasing hormone is cotropin releasing hormone is excreted by the embryo. (con’t on excreted by the embryo. (con’t on next slide)next slide)

CHEM 100/ Newer itemsCHEM 100/ Newer items_ Pregnancy spurs a tumor Pregnancy spurs a tumor

suppressor. suppressor. _ Women who undergo a full term Women who undergo a full term

preg-nancy at an early age are less preg-nancy at an early age are less likely to develop breast cancer than likely to develop breast cancer than those who do not become pregnant.those who do not become pregnant.

_ Reason: During pregnancy a Reason: During pregnancy a protein called P53 is secreted that protein called P53 is secreted that protects against carcinogens and protects against carcinogens and radiation. Con’t on next slide.radiation. Con’t on next slide.

CHEM 100/ New CHEM 100/ New materialmaterial

_ This hormone stimulates a This hormone stimulates a protein that suppresses the protein that suppresses the mother’s immune system to mother’s immune system to protect the embryo.protect the embryo.

_ Information from B.Narder, Information from B.Narder, “Sci. News” , vol 160 (20 Oct “Sci. News” , vol 160 (20 Oct ‘01) p. 247‘01) p. 247

CHEM100/An CHEM100/An Alternative New Alternative New

Material/latex condom?Material/latex condom?_ What about condoms as an What about condoms as an alternative to steroid based birth alternative to steroid based birth controls.controls.

_ It is well known that the pill and It is well known that the pill and other hormone based birth control other hormone based birth control does not prevent sexually does not prevent sexually transmitted disease STD.transmitted disease STD.

_ Condoms are touted as a method to Condoms are touted as a method to prevent transmission of STDs. (Next prevent transmission of STDs. (Next Slide)Slide)

CHEM 100/An CHEM 100/An Alternative? Alternative?

New Material/latex New Material/latex condomscondoms_ The U.S.Government Agency National The U.S.Government Agency National

Institutes of Health(NIH) has Institutes of Health(NIH) has recently released a report that shows recently released a report that shows the effectiveness of condoms is weak the effectiveness of condoms is weak or inconclusive. or inconclusive.

_ There is evidence that condoms can There is evidence that condoms can reduce incidence of AIDS and reduce incidence of AIDS and gonorrhea, but not herpes, syphilis, gonorrhea, but not herpes, syphilis, and human papillomavirus(next slideand human papillomavirus(next slide))

CHEM 100/ An CHEM 100/ An Alternative? New Alternative? New

Material/Latex CondomMaterial/Latex Condom_ The centers for disease control The centers for disease control

(CDC) and Food and Drug (CDC) and Food and Drug Administration (FDA) has Administration (FDA) has pamphlets saying that con-doms pamphlets saying that con-doms are effective in all STDs. are effective in all STDs.

_ There is little or no evidence for There is little or no evidence for this claim according to this this claim according to this recent report from the( NIH). recent report from the( NIH). (Next Slide)(Next Slide)

CHEM 100/ New CHEM 100/ New Material/Latex Material/Latex

CondomsCondoms_ Although some in congress are Although some in congress are

saying that this is just another saying that this is just another government cover-up, we (Chem government cover-up, we (Chem 100) can see it as related to the 100) can see it as related to the tentative nature of science. (next tentative nature of science. (next slide)slide)

_ REF: Kinkaid, C. “Unsafe Sex” REF: Kinkaid, C. “Unsafe Sex” American Legion Magazine, Dec. American Legion Magazine, Dec. 2001, p. 46.2001, p. 46.

CHEM 100/LatexCHEM 100/Latex

_ The formation of latex polymer The formation of latex polymer results when the monomeric units results when the monomeric units form a polymer.form a polymer.

_ These units will not polymerize These units will not polymerize while in a basic medium.while in a basic medium.

_ As demonstrated in class, adding As demonstrated in class, adding some acid allows the latex some acid allows the latex monomers to polymerize to a monomers to polymerize to a rubber ball.rubber ball.