stephen holt md-nutraceuticals 2010
TRANSCRIPT
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A REVOLUTION IN MEDICINE
Questioning allopathic medicine
Increased self-reliance of patients
Portability of healthcare The pharmaceutical revolution
DSHE Act, 1994
Identifying the first line option
Prevention vs. treatment
Edutherapy
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DIETARY SUPPLEMENTS
Evidence-based
Borrowed science Bioequivalence
Pharmaceutical sciences Who owns the intervention?
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PUBLIC HEALTH INITIATIVES
The obesity pandemic
Obesity-related disease
The Metabolic Syndrome X Menopause management
Osteoporosis
Sleeplessness
Digestive disorders
Cancer prevention
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THE OBESITY PANDEMIC
Global
Low carb diet craze
Diabesity
Obesity-related disease
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DIABESITY
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A LITANY OF DIETS
ATKINS DIET
ZONE DIET
CARBOHYDRATE ADDICTS
DIET
SOUTH BEACH DIET SUGARBUSTERS DIET
BEYOND ATKINS
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ENHANCING LOW CARB DIETS
Lifestyle change
Exercise
Behavior modification Rough calorie counting
Dietary supplements that combat insulin
resistance and components ofSyndrome X
New diet revolution has health
initiative
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THE UNKNOWN EPIDEMIC
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SYNDROME X PREVALENCE US
ADULTS
ATP 111, JAMA, Jan 16, 2002
8814 Participants
Data 1988-1994 with 2000 census data 47 million US residents with Syndrome
X
Forbes Magazine, August 6, 2001 70 million Americans with Syndrome X
Children 2% prevalence ?
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THE PUBLIC HEALTH RISK
Syndrome X increases risk for :
Maturity Onset DiabetesMellitus
Cardiovascular Disease
Cardiovascular Deaths
Deaths from ALL CAUSESAm.J.Epidemiol, 148, 958, 1998.
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INTEGRATED MEDICINE FOR
SYNDROME X
While proper management of the
individual abnormalities of this
syndrome can reduce morbidityand mortality, it seems unlikely that
management of the individual
abnormalities of this syndromeprovides better outcomes than a
more integrated strategy, - CDC,
Atlanta, Ga.
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THE X FACTORS
Insulin
resistance
Obesity High blood LDL
Low blood HDL
Slow clearance
of fats from
blood
Cholesterol
synthesis in the
liver Blood clotting
Adverse lifestyle
Serum uric acid
Homocysteine
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GLUCOSE TOLERANCE WITH SOLUBLE FIBER
THE PHYSIOLOGICAL BASIS OF THE GLYCEMIC
INDEX
Holt S, et al
Effect of Gel
Fiber
Lancet,
March 24th, 1979.
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GLUCOSE TOLERANCE WITH SOLUBLE FIBER
SLOW SUGAR ABSORBTION BY STOPPING
STOMA
CH EMPTYING
Holt S, et al
Effect of Gel
Fiber
Lancet,
March 24th, 1979.
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SUPER-SIZING AMERICA
Americans exude
complacency about
their overweight status
Obesity is part of ametabolic syndrome
Syndrome X is under
diagnosed and often
mistreated by
conventional medicine
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SYNDROME X NUTRITIONAL FACTORS
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SYNDROME X NUTRITIONAL FACTORS
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MENOPAUSE MANAGEMENT
47 million confused mature
females
Benefits of HRT outweighed byrisks
Menopause does not fit disease
model
Nave notion of estrogen
deficiency
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HRT
Cardiovascular risk
Cancer promotion
Cognitive decline
Quality of life
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EVIDENCE-BASED,
COMBINATION SUPPLEMENT
Black cohosh
Soy isoflavones
L-theanine Evening primrose oil
Dong quai
Chasteberry Gingko biloba
Synergy: CombinationsReference:Annals of Internal Medicine,
Vol. 137 No. 10, 2002
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OSTEOPOROSIS
Lifestyle
Calcium is not enough
Complex formulations for nutritionalsupport:
calcium, soy isoflavones, ipriflavone,
D3, zinc, copper, manganese, boron,
antioxidants
B6, B12, folic acid
Action today for health tomorrow
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SLEEP THE NATURAL WAY
Lifestyle
Hypnotic drugs are dangerous and
addictive Nutritional support: Complex formulations
Valerian, chamomile, passion flower, lemon
balm, skullcap, hops, ashwagandha
5 HTP, magnesium, melatonin, niacin, B6,
folate
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GI SUPPLEMENTS
Pooping for health
Enzymes
Probiotics
Prebiotics
Detox
Acid-related disorders
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REAL ADVANCES IN GI
Combining prebiosis,
probiosis, detox with enzymes
Biphasic neutralization or
inhibition of acid secretion:
natural acid neutralization,natural proton-pump inhibition
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ZANASEC
Patented, natural neutralization
with fava bean flour, calcium,
magnesium Proton-pump inhibition: Murakami
S, et al Inhibition of gastric H+, K +
- ATPase Planta Med, 57(1991)
A
nti-H. pylori
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CANCER PREVENTION
Antioxidants
Lipo-hydro access
Redox balance
Independent power
Green tea
Ellagic acid
Resveratrol
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CONCLUSION
Lifestyle change, good nutrition and well-
planned dietary supplements or functional
foods are first line options for prevention
and, at least, complementary management
of disease
Advances in nutraceutical medicine may
have more to offer than the next me-toodrug