stem cells in extraembryonic lineages and human development stem cells derived from amniotic fluid...
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Stem Cells in Extraembryonic Lineages and Human Development
Stem Cells Derived from Amniotic Fluid and Placenta (Carlson Ch. 17)Stem Cells in Early Development (Lanza 13)
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Early Implantation
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Stem Cells in Early Development
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Early Human Development
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Initiating Gastrulation in the Mouse
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Differentiation to Germ Layers in Vivo
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Extraembryonic Nodal Required for Anterior and Posterior mesoderm formation
Houng et al 2011 Development
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Nodal Pathway in Early Development
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Early in vitro differentiation of embryonic stem cell cultures
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Embryos without maternal ndr1 have normal mesoderm markers and head/neck
development
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Zebrafish Embryos Lacking Maternal and Yolk Sace Ndr2 show defective
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Primordial Germ Cells Are Responsible for Sperm and Egg in Adult Tissues
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Umbilical Cord Blood is a potent source of multipotent stem cells
Multipotent cells can be isolatedImmediately and cultured
11 x 10^6 cells/gram40g/tissue
Extensive in vitro renewal (55psg)
Multipotent markers expressedNo differentiation data?
2009 Schugar et al
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Amniocentesis A routine Genetic Screening procedure
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Developmental Fates of Embryonic and Adult Stem Cells
Diecke and Wu Molecular Therapy 2012
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Stem Cells from Amniotic Fluid used to treat myocardial damage
Yeh et al Biomaterials 2010
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Sheet shows more hAFSCs in heart tissue 4 weeks post injection