Car t cells

Bexalta --- mfr

The CAR technologies currently in development for hematologic cancers are a form

of adoptive cell therapy in which the patient’s T cells are cultured and then primed to

specifically recognize CD19, a protein expressed on normal and malignant cells of B-

cell lineage. Thus, CD19 presents a suitable tumor-associated antigen against which

to target anticancer agents (Figure).

The experimental technology has been successfully used to combat acute

lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), and non-Hodgkin

lymphoma, bringing many patients who participated in clinical trials into complete

remission (Table). The success of these therapies has caused much excitement, and

hopes are high that the CAR approach could one day become a frontline treatment

for many types of cancer, including solid tumors such as breast, ovarian, and

prostate cancers. - See more at: http://www.onclive.com/publications/oncology-

live/2014/november-2014/bringing-cars-to-market-novel-t-cell-therapies-make-

rapid-progress-despite-challenges/1#sthash.n2eRHgDl.dpuf

Cfg 166 deafness

Cardio metabolic--- opththa

Be non myopic --- tradeoffs on curative treatment..

Plst 1.84

--- clbs

Caladrius Biosciences is an American biopharmaceutical company active in the field of stem cell therapy

and regenerative medicine, particularly of cardiovascular disease. Wikipedia

Investigational New Drug (IND) Application

2:45pm – 3:00pm AGTCAGTC is developing cures for rare

lung and eye diseases, offering hope to patients with unmet medical needs

3:00pm – 3:15pm Oxford BioMedica

3:15pm – 3:30pm

ReNeuron

Cell Therapy Ltd.

34 20 min

35

BALLROOM 2

BioLife Solutions

4:15pm – 4:30pmMaxCyte Terumo

MaxCyte

BCT

4:30pm – 4:45pm

MaxCyte

4:45pm – 5:00pm TaiwanBio

5:00pm – 5:15pm

BrainStorm Cell Therapeutics

5:15pm – 5:30pm GenVec

5:30pm – 5:45pm REGENXBIO

5:45pm – 6:00pm Avita Medical

DAY 2

Data & Safety Monitoring Boards (DSMBs)

http://www.fda.gov/AboutFDA/CentersOffices/OfficeofMedicalProductsandTobacco/CBER/

Uniqure is ffunded -----