statins and polyketides

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Functional frameworks of important drugs in the cholesterol synthesis pathway

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Statins: Cholesterol-Lowering DrugsHMG-CoA Reductase Inhibitors

Lipitor (Atorvastatin)marketed by Pfizer

Crestor (Rosuvastatin)marketed by Astra Zeneca

Compactin (Mevastatin)Lovastatin (Mevacor)[Isolated from the fungus [Isolated from the fungusPenicillium citrinium]Aspergillus terreus]

Zocor (Simvastatin)MK-733marketed by Merck

Polyketide Natural ProductsRapamycinFK 506 AzithromycinErythromycin

TetracyclineEpothilones

Taxol (Paclitaxel)Discodermolide

AmphotericinRadicicol

Oligomycin

Polyketide Biosynthesis

Association between statins and clinical outcomes … between statins and clinical outcomes among men ... (RP) are the key ... control) studies examining

Statins and New-Onset Diabetes Mellitus and Diabetic Complications

Kinetic Statins Copia

Utilization of statins and LDL-cholesterol target

Statins and Myoglobin

Statins and the autonomic nervous system

Statins Dont Work

Functional Gene-Guided Discovery of Type II Polyketides ...€¦ · Functional Gene-Guided Discovery of Type II Polyketides from Culturable Actinomycetes Associated with Soft Coral

Statins and Congenital Malformations

GBIHC180MR Statins Market to 2018 sample - … Market to 2018 - Executive Summary Statins Market to 2018 - Executive Summary Statins (HMG-CoA reductase inhibitors), the first line

Bioactive Marine Polyketides as Potential and Promising Drugs€¦ · Polyketides are constructed as highly oxygenated stereo chemically-enriched scaffolds, sometimes with the characteristic

Supplementary Material Associations between statins and

Engineered polyketides: Synergy between protein and host ... · Polyketides encompass one of the largest classes of chemically diverse natural products. With thousands of known polyketides,

polyketides and terpenes › Chem564pdfs › polyketides and terpenes.pdf · polyketides and terpenes.ppt Author: Thomas Minehan Created Date: 8/24/2017 10:12:34 PM

Pharmacological Effects of Statins

Statins and Diabetes

The Current Status of Statins in Stroke Prevention - …medcraveonline.com/JNSK/JNSK-01-00014.pdf · The Current Status of Statins in Stroke Prevention ... benefits of statins in

polyketides and terpenes - tminehan.comtminehan.com/Chem564pdfs/polyketides and terpenes.pdf · Thioesters utilized for Claisen Condensations Sulfur is a better leaving group than

are statins nephroprotective?

Biotechnology of polyketides: New breath of life for the ... · Biotechnology of polyketides: New breath of life for the novel antibiotic genetic pathways discovery through metagenomics

WHEN AND HOW TO PRESCRIBE STATINS

226 statins are overrated

Statins Talk 2009

Production of Polyketides by Saccharomyces cerevisiae THESIS with front page.pdf · Since many useful polyketides either originate from sources that are difficult or even impossible

Polyketides, Toxins and Pigments in Penicillium marneffei€¦ · Polyketides are synthesized via a complex enzymatic system consisting of various kinds of polyketide synthases (PKSs)

Statins for Primary Prevention

1. Introduction to Natural Products Chemistry · RA Macahig FM Dayrit . 5. Polyketides (Dayrit) 2 ... Polyketides (Dayrit) 4 • The polyketides have great diversity of structures

MYTHS- CHOLESTEROL ,HEART ATTACK and STATINS

The Relationship between ACE Inhibitors, Statins and Pneumonia

Cholesterol and Statins · Cholesterol and Statins Author: Center for Drug Evaluation and Research Subject: Cholesterol and Statins Keywords: statins; cholesterol; infographic; reduce;

Formicamycins, antibacterial polyketides produced by

statins and protein p - CSIC

Pleiotropic Eff of Statins

Sampling Terrestrial Environments for Bacterial Polyketides€¦ · Abstract: Bacterial polyketides are highly biologically active molecules that are frequently used as drugs, particularly

STATINS ANTI-CHOLESTEROL AGENTS