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Starting Up and Running Health Enterprise East Ltd

A Case Study of a Limited Company A Case Study of a Limited Company Operating inside the National Health Operating inside the National Health Service – and a Historical PerspectiveService – and a Historical Perspective

Masterclass March 12Masterclass March 12thth 2010 2010Professor Alan BarrellProfessor Alan Barrell

Chairman – Health Enterprise East LtdChairman – Health Enterprise East Ltd

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A Preview The Nations Health and the NHS- Dilemmas and The Nations Health and the NHS- Dilemmas and

ChallengesChallenges Health Services in the East of England Health Services in the East of England A bit of history – healthcare Innovation is NOT easy !A bit of history – healthcare Innovation is NOT easy ! Creativity and InnovationCreativity and Innovation Enterprise, Entrepreneurship and Enterprise HubsEnterprise, Entrepreneurship and Enterprise Hubs Health Enterprise East Ltd – Start Up, Progress and Health Enterprise East Ltd – Start Up, Progress and

plansplans Discussion and DebateDiscussion and Debate

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Chairman of Health Enterprise Chairman of Health Enterprise East, also wearing other hatsEast, also wearing other hats

Chairman – NHS Chairman – NHS Regional Regional

Innovation CouncilInnovation Council

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Does our “Eye on the World” see much change?.... change?.... Our context….Our context….

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Dilemma – Dilemma – Population Population and Ageingand Ageing

More More Healthcare Healthcare – Reduced – Reduced BudgetsBudgets

Innovation is Essential

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Crisis ?.......or Crisis ?.......or Opportunity?Opportunity?

危机

Creativity and Innovation beat Despair Creativity and Innovation beat Despair any day! Call to action for any day! Call to action for

EntrepreneursEntrepreneurs

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We will deliver year on year improvements in patient experience

We will extend access guarantees to more of our services

We will ensure that GP practices improve access and become more responsive to the needs of all patients

We will ensure that NHS primary dental services are available locally to all who need them

A better patient experience Improving people’s health

We will ensure fewer people suffer from, or die prematurely from, heart disease, stroke and cancer

We will make our health service the safest in England

We will improve the lives of those with long term conditions

Reducing unfairness in health

Working with our partners, we will reduce the differences in life expectancy between the poorest 20% of our communities and average in each PCT

We will ensure healthcare is as available to marginalised groups and looked after children as it is to the rest of us

We will cut the number of smokers by 140,000

We will halt the rise in obesity in children and then seek to reduce it

What we have PLEDGED in Healthcare for the What we have PLEDGED in Healthcare for the East of England - MISSIONEast of England - MISSION

The Ten Programme Boards • Staying Healthy

• Mental Health

• Maternity and Newborn

• Children's’ health

• Planned Care

• Acute Care

• Long Term Conditions

• Palliative and end of life care

• Patient safety

• Patient and carer experience

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A new focus on our vision

QualityQuality

PreventionPrevention

InnovationInnovation

ProductivityProductivity

EngagementEngagement

AnalysisAnalysis

IdeasIdeas

Leadership and Leadership and Talent Talent

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Regional Innovation Fund £1.94M in Regional Innovation Fund £1.94M in 2009/102009/10

Long term conditions - priority for our QIPP agenda

2009/10 RIF focused on Long Term Conditions innovations

Emerging priority areas: Patient engagement and co-productionPersonal health plansSupported self careCommissioning integrated pathways

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Compact with industry Two way communicationsTwo way communications

Set out vision and needs of NHSSet out vision and needs of NHSLearn about range of products and devicesLearn about range of products and devices

Translating NHS Long Term Conditions needs to Translating NHS Long Term Conditions needs to industryindustry

‘‘Founder member’ of Cambridge Network Founder member’ of Cambridge Network healthcare special interest grouphealthcare special interest group

Sponsored ‘ Partnership with NHS’ award from Sponsored ‘ Partnership with NHS’ award from Eastern Region Biotech InitiativeEastern Region Biotech Initiative

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From a great man – Polymath – 600 years ago…. Starting our sense of

History….

Our Our challenges challenges in contextin context

Is all this Is all this anything anything newnew ? ?

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He gave us He gave us beauty as beauty as

well as well as sciencescience

A Giant A Giant amongst amongst men….men….

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Leonardo….

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Leornado Da Vinci….

But the History of But the History of Medicine and Medicine and Great Discoveries Great Discoveries goes back much goes back much further….further….

Chinese and Chinese and Egyptian Egyptian Discoveries and Discoveries and Practices have Practices have survived until survived until todaytoday

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Great Innovations can meet even greater opposition

Ignatz Philip Ignatz Philip

SemmelweisSemmelweis

Wash handsWash hands

Classical workClassical work

18471847

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AdoptionAdoption of the Semmelweiss Innovation – still not there TODAY ! of the Semmelweiss Innovation – still not there TODAY !

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Streptococcus pyogenes

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“Chance favours only the prepared mind”

BacteriaBacteria Louis Louis PasteurPasteur

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Joseph Lister and Antisepsis

Transformational work….Revolutionised Transformational work….Revolutionised potential for Surgery and Medicine potential for Surgery and Medicine generallygenerally 1.1. Anaesthetics – Horace WellsAnaesthetics – Horace Wells

2.2. Antibiotics – Antibiotics – Alexander FlemingAlexander Fleming

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What Alexander Fleming might have seen in 1928….and what What Alexander Fleming might have seen in 1928….and what doctors and technicians still see today….doctors and technicians still see today….

Remember Louis Remember Louis Pasteur’s Pasteur’s assertion – assertion – ““Chance favours Chance favours only the prepared only the prepared mind….”mind….”

A “failed” A “failed” experiment – led to experiment – led to the discovery and the discovery and development of development of Penicillin – and Penicillin – and many more many more antibiotics….antibiotics….

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Innovators and Innovators and Entrepreneurs Entrepreneurs

have often been have often been great improvisersgreat improvisers

From old From old washing washing

machines and machines and car parts to….car parts to….

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Willem Kolff’s first Drum Kidney Machine - 1942Willem Kolff’s first Drum Kidney Machine - 1942

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Innovation is a Innovation is a journey – journey – notnot a a destination….destination….

From drum From drum to coil….and to coil….and it goes on..it goes on..

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Sir Frederick Banting – Nobel Laureate – From Canada

Diabetes – Diabetes – major killermajor killer

INSULIN ! He INSULIN ! He was 21 when he was 21 when he

made the made the discovery !discovery !

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Three Converging RevolutionsThree Pervasive Technology Platforms – looking at Diverse

Science and Innovation and how Science can become Products and Practice

BioTechPharmaceuticals

DiagnosticsResearch/Info

ToolsIndustrial

GenomicsBioinformatics

Proteomics

INFO TECHHardwareSoftware

Communications

NANO TECHElectricalStructural

BiomedicalEnergy & Environment

BiosensorsBiochipsBioelectronics

MicrofluidicsNanobiotechnology

Drug Delivery

NanodevicesNanosensors

Nanoelectronics

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Closeness of Learning, Research and Practical Application

“The Innovation Campus” – Cambridge is one BIG Innovation Campus !

R&D Education

Applications

Where open innovation, symbiosis, synergy and new companies can thrive

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Converging Technologies in MedTech

I.C.T.

BioTech

Advanced

Manufacturing

Engineering

Medical

Technology

Electronics

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Role Models

Infrastructure

Charactersitics of RegionsCharactersitics of Regions planning to be Leaders in planning to be Leaders in Sustainable Technological Development – including in Sustainable Technological Development – including in

Medical SciencesMedical Sciences

Knowledge Centers Entrepreneurs & Role Models Money Capital Markets Infrastructure Cluster Policy Presence of International

Companies Networks Government Quality of Life

MindsMinds without Borders – Global Global MindsetMindset

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From Idea to Reality – A New Enterprise - Free From Idea to Reality – A New Enterprise - Free Standing – or in a Corporate Structure….Standing – or in a Corporate Structure….

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MedTech – from Idea, to Innovation to Reality – needs

Patient CapitalPatient Capital ….

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Some Destinations on the JourneyPut your own timescale in….and - imagine

costs….££££

Ideas Plans

Designs Regulations

Multi-skilled teams More Plans and Approvals Prototyping and Validation

Manufacturing and Final Testing Clinical Acceptance and Validation Marketing and into use….REALITY!

Revenues, Profits, Returns, Patient Benefits

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Incubation and Implementation –MedTech – a world

of….complexitycomplexity

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But the Commercial Markets are BIG………and But the Commercial Markets are BIG………and growing….growing….

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Medical Companies, like all others, that fall behind and don’t compete may not survive….Competition encourages Investment in Innovation

40Innovation happens mostly with USERS not SUPPLIERS Innovation happens mostly with USERS not SUPPLIERS

The Internet has REVOLUTIONISED Product Development and The Internet has REVOLUTIONISED Product Development and Innovation in many areas – including HealthcareInnovation in many areas – including Healthcare

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And then….we And then….we have the Wireless have the Wireless Connection Connection RevolutionRevolution

Will you have Will you have “Your GP in “Your GP in your Handset in your Handset in the future ?”the future ?”

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Integrated Technical Skill Base

LIFE SCIENCES

CHEMISTRY & MATERIALS

MICROFABRICATION

OPTICS, ACOUSTICS & PHOTONICS

ELECTRONICS & COMMUNICATIONS

ENGINEERING

Visions of the future A Multidisciplinary CompanyVisions of the future A Multidisciplinary Company

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An example already there today - Philips is present across the entire care cycle

- extending healthcare from the hospital to the home-and moved its R & D to Cambridge in 2008

Diagnostics

Treatment

Follow Up

Operating roomMonitoring

Imaging

Intensive Care unitMonitoring

PersonalHealthcare

Remote monitoringDiagnostics

Imaging

Pre-Hospital/AmbulanceMonitoring

EmergencyResponseServices

Treatment

Diagnosis

Prevention

Rehabilitation

Management

Consumer HealthcareSolutions

Diagnostics

““The array of health services and care settings that address health promotion, disease prevention, and the diagnosis, treatment, The array of health services and care settings that address health promotion, disease prevention, and the diagnosis, treatment, management, and rehabilitation of a disease, injury, and/or disability.”management, and rehabilitation of a disease, injury, and/or disability.”Center for Disease Control and Prevention (CDC), US Government`Center for Disease Control and Prevention (CDC), US Government`

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How about some IMAGINATION ? – It IMAGINATION ? – It seems necessary….seems necessary….

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Einstein on IMAGINATION….

“Imagination is more important than knowledge. Knowledge is limited. Imagination encircles the world”

Albert Einstein 1879 - 1955

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“You look at things and ask -

why? but I dream of

things that never were and ask -

George Bernard ShawGeorge Bernard Shaw

why not?”

Opportunities for Entrepreneurs -Healthcare

needs them !

A matter of MINDSETA matter of MINDSET

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Against this history and background ….Health Enterprise East Ltd – facing the Challenges of Implementing Innovation – Implementing Innovation – looking for more looking for more

innovators and heroesinnovators and heroes

An NHS Innovation Hub part of An NHS Innovation Hub part of the national NHS Innovations the national NHS Innovations NetworkNetwork

A not for profit company A not for profit company limited by guaranteelimited by guarantee

Five years old and going Five years old and going strongstrong

51A TOP TEAM – Ready and Willing to help YOU realise OpportunitiesA TOP TEAM – Ready and Willing to help YOU realise Opportunities

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Health Enterprise East – Founded 2005

We provide advice, support and We provide advice, support and resources to turn the ideas of NHS resources to turn the ideas of NHS

staff into new products and staff into new products and servicesservices

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Health Enterprise EastHelps NHS staff to identify and evaluate

innovative new ideasProvides funding for filing of patents,

designs rights & other registerable IPDevelopment funding available to

progress new ideas Negotiates commercial deals on behalf

of staff and their Trusts

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Annual Innovation Competition

Open to all NHS staff in the Region

5 categories:- Medical Technology Software, IT and Computers Infection controlPrevention & wellbeingPublication & training aids

Celebratory Awards Dinner£20k prize moneySponsored by companies

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Medtech Services – Helping Company Access and Getting Innovative Systems

Evaluated – “Opening Doors”

Help companies access NHS Help companies access NHS expertiseexpertise

Source of revenue for NHS Source of revenue for NHS staffstaff

Expose NHS staff to the latest Expose NHS staff to the latest technological innovationstechnological innovations

Industry Experts and IT and Industry Experts and IT and Software Executives in TeamSoftware Executives in Team Dr Juan Roman, HEE Dr Juan Roman, HEE

Medtech Services ManagerMedtech Services Manager

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Working together to PUT Innovative Products and Services to work –

Some Issues for us allBalancing Process and Safety with InnovationBalancing Process and Safety with InnovationFinding and Exploiting Innovation – BarriersFinding and Exploiting Innovation – BarriersAdoption and DiffusionAdoption and DiffusionThe “Top Down” – “Bottom Up” DilemmasThe “Top Down” – “Bottom Up” DilemmasThe Minefield of Regulatory Standards and The Minefield of Regulatory Standards and

Harmonisation in the EC.Harmonisation in the EC.Leadership and Creating an Innovative MindsetLeadership and Creating an Innovative MindsetCare “Everywhere” – Home, Community, Care “Everywhere” – Home, Community,

Hospital, Work – and Hospital, Work – and need for connectivityneed for connectivity

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In In Pursuit of of Excellence ! Excellence !

““Excellence can be achieved, if we:Excellence can be achieved, if we:Care more than others think is wise,Care more than others think is wise,Risk more than others think is safe,Risk more than others think is safe,

Dream more than others think is practical,Dream more than others think is practical,Expect more than others think is possibleExpect more than others think is possible.”.”

Deborah Johnson-RossDeborah Johnson-Ross

Excellence in Medicine and Medical Technology is everyone’s dream and in the West our expectation