staar review central dogma
DESCRIPTION
Central Dogma for STAAR reviewTRANSCRIPT
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DNA RNA PROTEINTHE CENTRAL DOGMA
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BELL RINGERWhich cellular process takes place in the ribosomes that are bound to the endoplasmic reticulum?
A. The breakdown of waste material
B. The conversion of radiant energy to glucose
C. The synthesis of new proteins
D. The replication of nucleic acids
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Objective
http://www.pbs.org/wgbh/nova/body/rnai.html
(first 3:10)
We will identify the components of DNA and RNA and explain the process of protein synthesis.
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DNA Structure:DNA resembles a twisted ladder.
Sides of ladder (Backbone) = Deoxyribose Sugars and Phosphates
Rungs of ladder (middle) = Nitrogen Bases
Hydrogen bonds= weak
bonds holding the nitrogen bases together
Watson & Crick
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DNA Nucleotides:Subunits that make up DNA
3 Parts:
1. Phosphate group
2. 5 Carbon Sugar (Deoxyribose)
3. Nitrogen-Base
PBS!!!
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Base PairingNitrogen Bases are held together by weak hydrogen bonds.
Nitrogen Bases:
Adenine, Thymine, Guanine, Cytosine
A with T (Apple in the Tree)
C with G (Car in the Garage)
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YOUR TURN!
WHAT ARE THE COMPLIMENTARY NITROGEN BASES TO THE FOLLOWING DNA SEGMENTS?
1. TTACGGCTA
2. ACTGGCTAT
3. GACTGGACT
4. CGCTACCGA
5. GGTCACAAT
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DNA: Blueprints of Life Worksheet
You have 5 minutes to answer the 9 questions on your half worksheet.
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DNA and RNA
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TranscriptionmRNA is synthesized from the DNA code
Occurs in the nucleus
http://www.stolaf.edu/people/giannini/flashanimat/molgenetics/transcription.swf
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Translation
Converting RNA to proteins
Occurs in the cytoplasm
http://vcell.ndsu.nodak.edu/animations/translation/movie-flash.htm
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Let’s Practice:Using a codon chart:
Which of these changes to the DNA triplet 3’ GCT 5’ will affect the protein produced?
A. GTT C. TCC
B. TCT D. GCA
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Now you practice by completing the following chart:
DNA mRNA tRNA Amino Acid
TCA
GGA
TAA
Methionine
UAA
TTT
AAA
Lysine
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YOU ARE ALMOST FINISHED!!!!!!!
YOUR EXIT TICKET FOR THE LESSON IS TO SYNTHESIZE YOUR OWN PROTEIN!:
1.Create 3 DNA codons
2. Show the complementary mRNA strand
3. Show the complementary tRNA strand
4. Write the corresponding amino acid for each codon.
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Cluster Exit Ticket
Complete the following on the note card you were given at the beginning of cluster.
Did this lesson have a coherent beginning, middle and end?
Was the pacing appropriate with opportunities for students who progress at different rates?