spondylodistitis.ppt
DESCRIPTION
mriTRANSCRIPT
By : Nurul Sakinah binti Rosli
Noor Tilawatu binti Kamaruddin
Nurul Hidayati binti Zainal Abidin
Nurhamidah binti Jamaludin
Clinical History Identification Data
Mr. M, 47 years old, Malay gentlemanEx-IVDU and heroin chaser past 10 year(5 months)Chronic smoker for past 30 years
Clinical PresentationPresented with alleged MVA 2 weeks prior to
admission. However, post trauma, he did not sustain any injuries except abrasion wound over right forearm.
But since then, he experiencing on and off numbness over lower limb, associated with pain over lower back and progressive weakness of lower limb.
2 days prior to admission, he started having difficulty in ambulation due to weakness-need aid of walking frame.
The numbness and weakness was associated with fecal incontinence, difficulty in urination and sensation of incomplete voiding.
Also claimed, having on and off numbness since 2 years ago but resolves spontaneously-frequently associated with blurry vision.
On admission, he complaint of lower back pain and weakness of lower limb and inability to ambulate.
Physical Finding
Patient was alert and concious, GCS:15/15
Tenderness over lower cervical and lumbar spine
NeurologyUpper Limb Right Left
Tone Normal Normal
Power (C5-T1)
5/5 5/5
Reflexes ++ ++
Sensation Reduced from T10 downwards bilaterally
Lower Limb
Right Left
Tone Normal Normal
Power: L2 3/5 3/5
Power: L3-S1
5/5 5/5
Reflexes ++ ++
What is spondylodiscitis?
Spondylodiscitis is an inflammation of the base and upper plates of the vertebra as well as the adjoining intervertebral disc and is frequently accompanied by spondylitis (inflammation of the vertebral body). Infectious spondylodiscitis is caused by bacteria, viruses, fungi or parasites and can result in deformed vertebral segments and neurological complications.
BASE PLATEINTERVERTEBRAL
DISCUPPER PLATEVERTEBRAL
BODYSPINALNERVE
SPINALCORD
SPINAL NERVE
FIBROUS RINGGELATINOUS
CORE
INTERVERTEBRAL DISC
Classification of Spondylodiscitis?
Bacterial caused Non Bacterial caused
Specific Non Specific
•Mycobacterium tuberculosis•Mycobacterium leprae•Brucella bacteria•Salmonella typhosa
•S.aureus•S.epidermidis•S.viridans•E.coli•P.aeruginosa•Pneumococci•Clostridium perfringens•Proteus mirabilis
Immunocompromised patients, •viruses•fungi
•Candida albicans• Aspergillus
•parasitic infection •tapeworms
(Echinococcus)
Diagnosis
Diagnostic Procedures
•recent bacterial infection
•recent surgery /therapeutic
procedures o• tuberculosis
or salmonellosis
• any autoimmune diseases or
diabetes mellitus
• location of pain• Any radicular or pseudo-radicular neurological symptoms
•BSR • CRP• WBC
(leukocytes)•PMN
elastase•Lymphocyte
•Tine test positive (tB diagnosis)
•histological (cellular) or
microbiological detection of the pathogen.•fine needle aspiration or
punch biopsies
•Conventional x-rays (AP and lateral
views)•Skeletal
scintigraphy•CT Scan
•MRI
Differential Diagnosis1. Trauma
2. Hip Pathology Hip dysplasia,Transient synovitis
3. Spinal pathology Spondylolysis,Spondylolisthesis,Disk herniation
4.Infections Urinary, Gastro intestinal, respiratory,Arthritis, Osteomyelitis, tuberculous spondylodiscitis
5.Tumoral Pathology
• Last unfused vertebra is taken as L5• There is loss of normal signal seen at the vertebral
bodies and bilateral pedicles of T9 and T10 vertebra which are hypointense on T1W images and mixed hyperintense-hypointense on T2W/STIR images. Post contrast, there is enhancement seen.
• The end plates of T9/T10 disc space ( inferior end plate of T9 vertebral body and superior end-plate of T10 vertebral body) are irregular. This finding is best appreciated on sagittal T1W images ( pre and post contrast). There is hyperintense signal seen at the T9/T10 disc space on STIR.
• There is a large peripherally enhancing epidural lesion seen extending from upper border of T9 vertebral body to lower border of T10 vertebral body , likely to be epidural collection/abscess. This epidural collection occupies the anterior and lateral aspects ( left>right) of the spinal canal. The spinal cord is compressed and is displaced posteriorly and to the right, with the narrowest diameter seen at T9/T10 level measuring about 0.7cm (AP) x 0.7cm (W). There is hyperintense signal (on T2W and STIR) seen at the spinal cord at this level but no obvious enhancement seen post contrast
• The epidural collection is also seen extending through bilateral exit neural foramina of T9/T10 level (left>right) and left exit neural foramen of T10/T11 level. The exiting nerve roots (mainly left exiting T9 nerve root) appear compressed. There is small paravertebral collection seen at T9/T10 level (noted on coronal T2W images),larger on the right measuring about 1.0cm (AP) x 0.8cm (W) x 1.9cm(CC).
At the lumbosacral spine, there is loss of normal intervertebral disc signal noted at L3/L4 level. The L3/L4 disc space is slightly narrowed. There are small posterior disc bulges noted at L2/L3, L3/L4 and L4/L5 levels.
At L2/L3 level, small posterior disc bulge is abutting theca sac with anteroposterior diameter of spinal canal measures 1.3 cm. No significant exit neural foramina narrowing. No evidence of exiting nerve roots compression seen.
At L3/L4 level, diffuse posterior sac bulge is abutting theca sac with anteroposterior diameter of spinal canal measures 1.2 cm. Bilateral exit neural foramina appeared narrowed. No evidence of exiting nerve roots compression seen.
At L4/L5 level,the posterior disc bulge is abutting theca sec with anteroposterior diameter of spinal canal measures 1.2 cm. Bilateral exit neural formina appeared narrowed. No evidence of exiting nerve roots compression seen.
At cervical spine, there is loss of normal signal of the intervertebral discs. The C3/C4 disc space appears narrowed.
Posterior disc-osteophyte complexes noted, moat prominently seen at C3/C4 and C6/C7 levels.
At C3/C4 level, posterior disc-osteophyte complex is compressing theca sac with anteroposterior diameter of spinal canal measures 1.0cm. bilateral exit neural foramina are narrowed (left>right) with possible impingement on bilateral exiting C4 nerve roots.
At C6/C7 level, posterior disc-osteophyte complex is compressing theca sac with anteroposterior diameter of spinal canal measures 0.9cm. Bilateral exit neural foramina are narrowed with possible impingement on bilateral exiting C7 nerve roots.
Spinal cord ends at L1/L2 level. Normal cervico-medullary junction. No Chiari malformation.
No other focal lesion seen at visualized spinal cord.
The vertebral body heights are preserved
No other focal lesion seen at visualized vertebral bodies
IMPRESSION
1. The MRI findings at T9-T10 levels are suggestive of spondylodiscitis ( due to TB? Pyogenic) with large epidural abscess collection compressing on the spinal cord. The hyperintense signal seen at the spinal cord at this level could be due to oedema. Small paravertebral collection is also noted.
2. Degenerative disc disease noted at lumbosacral spine at L2/L3, L3/L4 and L4/L5 level. There is no spinal canal stenosis and no evidence of exiting nerve compression seen at these levels.
3. Cervical spondylosis, most prominently at C3/C4 and C6/C7 levels with possible impingement on bilateral exiting C4 and C7 nerve roots.