Speak up about xerostomia and deliver comprehensive care to your patients.

• Maintainingthemouth’spHlevel

• Remineralizingteeth

• Protectingenamelanddentintoothsurfaces

Most xerostomia products fall short. Managingpatientswithxerostomiawillcontinuetobeachallengefordentistsaspeoplelivelongerandtakemoremedications.Patientsmaybeafraidtospeakupormayalreadybedisappointedwithover-the-counterproductsthatdon’tdeliverpromisedrelief.Patientsarelookingforfast,effectiveandconvenientrelief.Yet,theytypicallyfindthemselveshavingtomixpacketsofpowderinwatertorinsetheirmouthsrepeatedlyorneedingtoreapplyproductsfrequentlythroughouttheday.

Butyoucanhelprestorepatients’oralhealthandtheirconfidencetofindtheirvoiceandlivetheirlivestothefullest.

Why is saliva so important?Salivaisoneofthosethingsinlifethatyoudon’ttrulyappreciateuntilit’sgone.Saliva’sbasicfunction istokeepteeth,gumsandtissuesinsidethemouthmoist.Ithasanumberofbenefits,suchas:

• Aidingineatingandspeaking

• Protectingtissuesfrombacteriaandviruses

• Keepingthemouthclean

Xerostomia increases the risk of tooth decay and affects overall health.Letpatientsknowtheoralhealthrisksinclude:

• Dentalcaries

• Plaqueaccumulation

• Gingivitisorperiodontitis

• Candidiasisandotherinfections

• Angularcheilitisormucositis

• Traumaticorallesions

Advocate for your patients’ oral health.Yourpatientsmaycallitdrymouth,butxerostomiaisamoreseriousmedicalconditionthanitsnicknamewouldsuggest.Withmostcases,patients’dailylivesandoralhealthcanbesignificantlycompromisediftheirxerostomiaisnotdiscoveredearlyandmanagedeffectively.

Xerostomia is common — and commonly undetected. Thecausesofxerostomia,whichisassociatedwithadecreaseinthequantityandqualityofsaliva,arenumerous.Xerostomiacanbecausedorexacerbatedbymorethan700medications,bothover-the-counterandprescription.1Patientswithcertainhealthconditionsormedicaltreatments,suchasSjögren’ssyndrome,headandneckcancertherapy,anddiabetes,oftenexperiencexerostomia.Despitebeingacommonmedicalcondition,thesignsandsymptomsmaygounnoticedinaroutinedentalexam.It’sbeenreportedthattheincidenceofxerostomiainthegeneralpopulationisashighas65percent.2

Medications commonly associated with xerostomia:3

• Antiacneagents

• Antianxietyagents

• Anticonvulsants

• Antidepressants

• Antidiarrhealagents

• Antidysrhythmics

• Antihistamines

• Antinauseaagents

• Antipsychotics

• Anorexiants

• Antacids

• Bronchodilators

• Decongestants

• Diuretics

• Highbloodpressuremedications

• Musclerelaxants

• Narcoticanalgesics

• Nonsteroidal anti-inflammatory drugs(NSAIDs)

• Opioidanalgesics

• Parkinson’sdiseasemedications

• Sedatives

• Smoking-cessation agents

• Urinaryincontinence agents

The incidence of xerostomia in the general population is as high as

65%2

1Lamoreux,D.(2014,March11).Findingcomfortwithadrymouth.www.rdhmag.com/articles/print/volume-34/issue-3/features/finding-comfort-with-a-dry-mouth.html.2ADAScienceInstitute,C.(2017).OralHealthTopics:Xerostomia(DryMouth).JADA.www.ada.org/en/member-center/oral-health-topics/xerostomia.3 Sankar,V.,&Rhodus,N.(2015,October15).Xerostomia.www.aaom.com/index.php?option=com_content&view=article&id=107:xerostomia&catid=22:patient-condition-information&Itemid=120.

3M™ Xerostomia Management Solutions provide comprehensive care.Drymouthtreatmentdoesn’thavetostopatrelievingsymptoms.Youcanhelp protectyourpatients’oralhealthbyrecommendingaprogramincludingin-office fluoridetreatments,prescription-strengthtoothpasteandsalivastimulants.

4Mouly,S.,Orler,J.B.,Tillet,Y.,Coudert,A.C.,Oberli,F.,Preshaw,P.,&Bergmann,J.F.Efficacyofaneworallubricantsolutioninthemanagementofpsychotropicdrug-inducedxerostomia,JournalofClinicalPsychopharmacology2007;Volume27,No5.

Learn more: 3M.com/xerostomia

3M™ Vanish™ 5% Sodium Fluoride White VarnishProvideadditionalprotection foryourpatients withthiseasy-to-apply, extended-release-formula varnish.Itcontainsadded calciumandphosphateandmigratestoareasthatare difficulttoreach.

3M™ Clinpro™ 5000 1.1% Sodium Fluoride Anti-Cavity ToothpasteSendyour patientshomewith prescription-strengthfluorideprotectiontheycanusedaily tohelppreventcaries.BrushingwithClinpro5000toothpasteonceadaycreateshigh-qualitymineral,preventsminerallossandhelpsprotectagainstlesionprogression. Clinpro5000containsfluoride,calciumandphosphate—componentsfoundinsaliva thatarenecessaryforbuildingstrongteeth.Seebackcoverforprescribinginformation.

3M™ TheraMints™ 100% Xylitol Sweetened MintsThesegreat-tastingmintsstimulatesalivaflowtofighttheharmfuleffectsofdrymouth.Theyaresweetenedwithxylitol,anaturalsugarsubstitute,anddonotpromotetoothdecay.Xylitolalsohasantimicrobialandantibacterialeffects.

3M™ Xerostomia Relief SprayRapid,effective,prescription-strengthreliefofsymptoms inaconvenient,discreetspray.Inaclinicalstudy,92percent ofpatientssawanimprovementintheirdrymouthsymptoms.4

• Relievessymptomsofdrymouthforuptofourhours

• Lipid-basedspraymoistensandlubricatesthemucosa

• Providesrapidrelief

• Improvespatients’abilitytochew,taste,swallowandspeak

• Easyandconvenientapplication

• Availableonlybyprescriptionthroughadentalprofessional

Speak up when your patients can’t.Patientsmaynotrealizetheyhavexerostomiaorevenknowwhatitis.Theymaythinkthereisnothingtheycandoaboutit,orthatdrymouthisjustsomethingtheyhavetoacceptwithage. Andtheymaynotunderstandhowdamagingxerostomiacanbe.Forthesereasonsandothers,yourpatientsmaybesufferinginsilence.Butastheiroralhealthadvocate,youhavethepower tospeakup,helppatientsunderstandtheirxerostomiaandprovidewaystofightback.

Start by asking your patients about their symptoms.Ifapatientsaysyestooneofthesestatements,it’sworthwhiletofollowupwithadetailedmedicalhistoryandoralexam.Catchingdrymouthearlyisessentialtopreventingsignificanttoothdecay.

• Iamfrequentlythirsty,andmyphysicianhasruledoutdiabetes

• Idrinkbeveragesallday/nighttoquenchmythirstbutgetonlytemporaryrelief

• Ifrequentlyfeelasticky,tackysensationinmymouth

• I’venoticedaraworsoreandburningsensationinmymouthandonmytongue

• I’mhavingdifficultyswallowing,anditismorenoticeableatnight

• Ihavetroublespeakingandchewingmyfood

• Ihaveredsorespots/cracksatthecornersofmymouth

• MysignificantotherhastoldmethatIhavebadbreath

3M Oral Care2510ConwayAvenueSt.Paul,MN55144-1000USA

Phone1-800-634-2249Web3M.com/dental

3M,ESPE,Clinpro,VanishandTheraMintsaretrademarksof3Mor3MDeutschlandGmbH.PrintedinUSA.©3M2019.Allrightsreserved. 70-2013-7043-7(Rev5/2019)

Ordering Information

3M™ Vanish™ 5% Sodium Fluoride White VarnishItem # Product Information

12149C12149L12149M

3M™ Vanish™ 5% Sodium Fluoride White Varnish — 50 PackEach 50 Pack includes: 50 unit-dose packets (0.5ml each) of one flavor and applicator brushes in individual foil pouchesCherry FlavorMelon FlavorMint Flavor

12150C12150L12150M

3M™ Vanish™ 5% Sodium Fluoride White Varnish — 100 PackEach 100 Pack includes: 100 unit-dose packets (0.5ml each) of one flavor; 100 applicator brushesCherry FlavorMelon FlavorMint Flavor

12151C12151L12151M

3M™ Vanish™ 5% Sodium Fluoride White Varnish — Bulk PackEach Bulk Pack includes: 10 boxes of one flavor. Each box includes: 100 unit-dose packets (0.5ml each); 100 applicator brushesCherry FlavorMelon FlavorMint Flavor

Item # Product Information

12151CL 3M™ Vanish™ 5% Sodium Fluoride White Varnish Bulk Pack — Cherry & Melon FlavorsIncludes: 10 boxes (5 Cherry, 5 Melon). Each box includes: 100 unit-dose packets (0.5ml each); 100 applicator brushes

12151X 3M™ Vanish™ 5% Sodium Fluoride White Varnish Bulk Pack — Assorted FlavorsIncludes: 10 boxes (4 Cherry, 4 Melon, 2 Mint). Each box includes: 100 unit-dose packets (0.5ml each); 100 applicator brushes

3M™ TheraMints™ 100% Xylitol Sweetened MintsItem # Product Information

12119M 3M™ TheraMints™ 100% Xylitol Sweetened Mints — Mint Flavor Includes: 520-mint bottle with travel tin

3M™ Clinpro™ 5000 1.1% Sodium Fluoride Anti-Cavity Toothpaste – Prescription OnlyItem # Product Information

1211512115BG12115SM

Clinpro™ 5000 1.1% Sodium Fluoride Anti-Cavity Toothpaste — 4oz tubeVanilla Mint FlavorBubble Gum FlavorSpearmint Flavor

IMPORTANT INFORMATION ABOUT Clinpro™ 5000 1.1% Sodium Fluoride Anti-Cavity Toothpaste Brief Summary (For full Prescribing Information, refer to package insert.)

WHAT IS CLINPRO 5000? Clinpro 5000 1.1% Sodium Fluoride Anti-Cavity Toothpaste is a prescription strength toothpaste indicated for use in adults and children 6 years of age and older, as part of a professional program for the prevention and control of dental caries.

HOW SHOULD I TAKE CLINPRO 5000? Use once daily in place of conventional toothpaste unless instructed otherwise by a doctor or dentist. Apply a thin ribbon or pea-sized amount of Clinpro 5000 using a soft-bristled toothbrush and brush teeth for at least two minutes. After brushing adults should expectorate. Children 6 to 16 years of age should expectorate and rinse mouth thoroughly with water. Do not swallow.

WHAT ARE THE MOST COMMON SIDE EFFECTS OF CLINPRO 5000?

• Allergic reactions and other idiosyncrasies have been rarely reported.

• Repeated ingestion of high levels of fluoride may cause dental fluorosis.

• You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

WHERE SHOULD I GO FOR MORE INFORMATION ABOUT CLINPRO 5000? Ask your doctor or dentist if Clinpro 5000 is right for you. Go to www.3M.com/dental or call 1-800-634-2249.

3M™ Xerostomia Relief Spray — Prescription Only Item # Product Information

12137 3M™ Xerostomia Relief Spray – Two 10 mL vials

Order a supply from a 3M-authorized distributor and dispense prescription treatments directly from your office, or prescribe to your patients for mail-order through Transition Pharmacy (TPS). To download the TPS prescription form, visit 3M.com/RxFormTPS