south african medical research council building a healthy nation through research medical research...
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SOUTH AFRICANMEDICAL RESEARCH COUNCIL
Building a Healthy Nation Through Research
Medical Research Council Budget and Strategic Plan 2007/2008
Presentation to the Parliamentary Portfolio Committee on Health
Prof A D MBewuPresident, MRC
15 May 2007
Agenda
1. Mandate of the MRC2. Vision, Mission and Values3. Strategic Objectives4. Corporate Governance5. Research, Development and Technology Transfer6. Strategic Research Initiatives7. Key Strategic Initiatives8. Implementation of Shared Values9. MRC Budget10. Health Research Priorities11. Strategic Health Research Priorities12. MRC Personnel and Productivity13. Research Translation 14. Transformation 15. Conclusion
Mandate of the MRC
The mandate of the South African Medical Research Council is legislated in terms of Act 58, 1991 :
‘the objects of the MRC are, through research, development and technology transfer, to promote the improvement of the health and quality of life of the population of the Republic, and to perform such functions as may be assigned to the MRC by or under this Act’.
Vision and Mission
The vision of the is MRC :
‘Building a healthy nation through research’
The mission of the MRC is :
‘to improve the nation’s health and quality of life through promoting and conducting relevant and responsive health research’
MRC Shared Values
‘Cared’
• Communication : transparency, and freedom to challenge
• Accountability : responsibility, teamwork, leadership and participation
• Respect : dignity, honesty, fairness and integrity
• Excellence and innovation
• Development : reward and recognition
MRC Strategic Objectives The MRC mission is implemented through the following 9 Strategic Objectives : Promoting and conducting researchPromoting and conducting research is the core business and primary strategic objective of the MRC as aKnowledge producing organisation. Without research, the vision of the MRC of ‘building a healthynation through research’ cannot be achieved :
1. Research Strategy and Business Plan
Professional support for researchResearch cannot take place, and staff cannot develop, unless supported by corporate professional services :
2. Financial Model Strategy and Plan 3. Opportunity and Risk Management
4. Capacity Development5. Transformation and Development Plan
Research TranslationResearch makes no difference to health and quality of life unless it is translated into interventions such aspolicy, practice, products, and health promotion which can have an impact on the health and quality of lifeof the nation :
6. Innovation Management and Technology Transfer7. Informatics and Knowledge Management8. Research Translation9. Stakeholder Management
Corporate Governance
BOARD
President
Board and Office Manager
Exec. Secretary
Committee Secretary
Legal Services
Exec Man. Corp. Affairs
Vice President Research
Exec Dir Innovation & Technology
Exec Dir Finance Exec Dir Operations
ManagerOperations
ManagerInformationTechnolo
gy
Strategic Research Committee
Exec ManHuman Capital
Developmt
Exec ManResearch Admin &
Management
Exec ManStrategic Research Initiatives
Exec ManInformatics &
Knowledge Management
18 Intramural Unit Directors
25 Division Managers
1. National Collaborative Research Programme
2. Collaborative Research Group
3. Research Unit
4. Research Project
- Self-Initiated
- Developmental
- Rapid Response
5. Research and Technology Entities
- Research and Technology Platforms
- Biotechnology Programmes
6. Commercialisation Entities
Research, Development and Technology Transfer
National Collaborative Research Programmes
• Cardiovascular Disease and Diabetes
• CARISA
• IKS and African Traditional Medicines
• Tuberculosis
• Malaria
• Cross University Brain and Behaviour Research Initiative
• HIV and AIDS – NAPRA
Strategic Research Initiatives
• Italian HIV Vaccine Project - Phase II clinical trial - Health systems - HIV vaccine manufacture
• NIH Clinical Trial Unit – MTN, HIV vaccine, HPTN, ACTG, PACTG
• Nanotechnology – Mintek, WRC
• Gold-based pharmaceuticals – Mintek, Prof Chibale
• FIND Diagnostics – demonstration project of new diagnostic for MDR TB
• Telemedicine initiative in KZN – Dr Molefi, Prof Mars
• Proteomics – Prof Jonathan Blackburn
Research and Technology Entities - Research and Technology Platforms
* Primate unit* Traditional medicines manufacturing plant * Bioinformatics* High performance computing centre (Meraka)
- Biotechnology Programmes * SAAVI
Commercialisation Entities - Spinout companies and licensing agreements
* Gene Care : DNA-based cardiac diagnostic test* Stereotactic Neurosurgical Device
* Carotino * Diabetes : ZADEC * Telemedicine
* Genetic Ancestry * Traditional Medicines
Key Strategic Initiatives
Six Key Strategic Initiatives for 2007 were identified in Feb 2007:
• Corporate culture and implementation of shared values
• Improve performance management system • Improvement of quality of support directorates
• Grow funding of MRC • Review all policies of the MRC • Implement online management information system
Implementation of Shared Values
• Project office - electronic management system • Fraud prevention plan
• Whistle blowing
• Sexual harassment policy
• Communications
• Salary adjustments and promotions
• Organisational culture
MRC Budget
Source of income
2004/05
Rands thousands
2005/06 2006/07 2007/08
Baseline 154 388 157 284 180 000 190 710
Contract and Grant
162 853 176 000 236 000 244 000
Total
Year by year Increment
317 241
11%
333 284
5%
416 000
25%
434 710
5%
Changes in Budget Allocation
Divert more funds from the support services to research Operational funding for support reduced by 10% (R 3 124 000) in 2007 by 4% in 2006 to 2006 Operational funds and equipment for research increased by 16% (R 7 075 895) extramural – R4 970 000 intramural - R2 105 895
75% of research operating, capital, and capacity development funds are now apportioned to the extramural environment (R 39 212 070) and 25% to the intramural (R13 206 681).
* R1 050 000 extra for self-initiated research* R1.9 million for capital equipment in the 45 Units* R750 000 in seed funding for 3 new NCRPs* R3 455 895 extra for operating budgets of Units* R670 000 extra for capacity development
Health Research Priorities
Cause of Death
Research Units Mortality %
(Stats SA 2004)
Baseline Expenditure
Rands millions
Global Expenditure
Rands millions
(% of total)
HIV and AIDS
HIV Prevention Research
SAAVI
30? 6.2 94.8 (29)
Tuberculosis Clin and Biomedical
Epidemiol & Intervention
Cell Mol Biology
Mol Mycobacteriology
14 6.5 44 (14)
Heart and Stroke and Diabetes
Chronic Diseases
Cape Heart Group Exercise and Sports Diabetes Research
26 3.3 5.4 (2)
Health Research Priorities
Causes of Death
Research Units Mortality %
(Stats SA 2004)
Baseline Expenditure
Rands millions
Global Expenditure
Rands millions
(% of total)
Violence and Injury
Crime, Violence and Injury 9 2.7 2.7 (1)
Brain and Behaviour
Medical Imaging
Anxiety and Stress
1 2 2 (0.6)
Pneumonia and other infections
Respiratory and Meningeal Diarrhoeal Pathogens
Inflammation and Immunity Immunology of Infectious Disease
Genital Ulcer Disease
18 3 10 (10)
Cancer PROMEC
Oesophageal Cancer
Cancer Epidemiology
6 6.5 6.5 (2)
Health Research Priorities
Cause of Death
Research Units Mortality %
(Stats SA 2004)
Baseline Expenditure
Global Expenditure
(% of total)
Public Health
Research Burden of Disease Health Systems
Biostatistics
Cochrane Centre
Health Policy
Rural Health Transition Telemedicine
- 14.2 14.8 (4.5)
Nutrition Women, Maternal and
Child Health
Nutrition
Maternal and Infant Mineral and Metabolism Gender and Health
2
3
1
2.2
7.3 (2)
2.2 (1)
Environment and Health
Environment and Health 1 4.2 4.2 (2)
Health Research Priorities
Cause of Death
Research Units Mortality %
(Stats SA 2004)
Baseline Expenditure
Rands millions
Global Expenditure
(% of total)
Health Promotion
Health Promotion Alcohol and Drug Abuse
- 4.2 6.9 (2)
Malaria
African Traditional Medicines
Malaria Indigenous Knowledge SA Traditional Medicines
1
-
8
1.1
95 (29)
9.1 (2.8)
Genomics and Proteomics
Human Genetics
Human Genomic Diversity Bone Research
Bioinformatics Cap Dev Receptor Biology
Liver Centre
2 20 20 (6)
Strategic Health Research Priorities
Strategic Health Research Priorities
Scenario One : Address all Health Research Priorities
Rands millions
Scenario Two : Seize all Health Research Opportunities
Rands millions
Capacity Development 26 52
Cardiovascular Disease 25 50
Capital Expenditure 20 40
National Collaborative Research Programmes
60 100
Strategic Health Research Priorities
Strategic Health Research Priorities
Scenario One : Address all Health Research Priorities
Rands millions
Scenario Two : Seize all Health Research Opportunities
Refurbishment 40 60
Human Resource Development
40 60
Innovation and Technology Transfer
20 60
TOTAL R 231 million R 422 million
MRC Personnel
The MRC is a ‘Knowledge creating company’ and people are therefore its most important resource :
PERSONNEL
854 intramural personnel
458 Research Scientists in 45 units150 Scientists in self initiated research projects216 PhD students150 Master’s students223 SAAVI personnel
In total ~ 2000 employed by or associated with MRC
Productivity
1993 2002 2004 2005 2006 2007
Peer reviewed 425 572 580 568 618 664publications
Staff 453 642 750 800 840 854
Productivity
MRC total : 45 Units, 618 publications : - from 302 senior scientists; ratio 2.2
Intramural : 18 Units, 198 publications : - from 126 senior scientists; ratio 1.60
Extramural : 27 Units, 420 publications : - from 175 senior scientists; ratio 2.40
Self initiated : 120 projects, …..publications, - from 120 senior scientists
ProductivityINPUTS
R204 Million Government (20% of government health research expenditure) R240 Million External incomeR444 Million
OUTPUTS
4 NRF ‘A’ Rated scientists2 Orders of Mapungubwe668 Peer reviewed publications (40% of South Africa’s health research output) 20 Patents – current and pending 20 Technical reports 49 PhD graduates per annum 50 M graduates per annum
Research Translation
MRC vision : ‘building a healthy nation through research’
Research makes no difference to health unless it is translated
GRIPPPP : Getting research results into : PolicyPracticePromotion andProduct
Impact 664 publications (Research Report) produce over 1 000 units of knowledgewith implications for policy and practice in all top 10 causes of death and diseaseIn addition to the Annual Report and Research Report; there is the opportunity to provide a Research Translation Report that would list the items of new knowledge generated by MRC researchers every year, and their implications for policy, practice, product development and health promotion
Transformation
Occupational Level BlackMar 2007
FemaleMar 2007
ExecutiveManagement
80 % 20 %
Senior Management 65 % 57 %
Middle Management 51 % 63 %
Skilled 85 % 72 %
Semi-Skilled 96 % 67 %
Unskilled 95 % 52 %
Total 82 % 67 %
838 personnel : Black African 410 (49%) Coloured 155 (18%) White 153 (18%) SA Indian 120 (14%)
Employment Equity : Percentages of Black Staff at every Level in 1997 and in 2007
14%15%
42%
55%
95%
98%
80%
65%
51%
85%
96%
95%
0%
10%
20%
30%
40%
50%
60%
70%
80%
90%
100%
1997 March 2007
Unskilled
Semi-Skilled
Skilled
Middle Management
Snr Management
ExecutiveManagement
ConclusionThe MRC Strategic Plan and Budget for 2007 will ensure that :
• The MRC continues to grow and develop its portfolio of research, development and technology transfer activities • There has been a consistent year on year increase in the quantity (7%) and quality of MRC
research publications, accounting for 40% of South Africa’s health research output
• The growth in the external income of the organisation continues at a more reasonable pace (5%); whilst the baseline grant keeps track with inflation (6%)
• Within the MRC there are increasing numbers of black and female scientists at doctoral and postdoctoral level
• Translation of research results into policy, practice, products and health promotion continues
• The MRC moves into the future confident that it can deliver on its mandate of using research, development and technology transfer to provide new health solutions for improving the health and quality of life of all South Africans
Conclusion
However : there is a need for additional funds to :
1. More adequately fund existing research efforts2. Train more scientists – especially black african scientists; and provide career
paths for researchers in general 3. Refurbish the ageing capital equipment in MRC research units4. Exploit new opportunities in research such as stem cell research, genomics and
proteomics, computational bioinformatics, behavioural science, and health economics
5. Provide more inputs for South Africa’s biotechnology and pharmaceutical industry
6. Exploit the biodiversity of South Africa in order to develop natural medicines and novel pharmaceuticals
7. Respond to health crises as they arise in terms of rapidly developing research and evidence-based solutions
8. Reduce the tendency to become ‘donor-driven’ in the MRC’s research portfolio 9. Improve the process of translation of research results into policy, practice,
product and health promotion
Building a healthy nation through research
http://www.mrc.ac.za