Sonja Hintz RN BSNTrue Health Medical Center

Naperville Illinois

This presentation will review current labs ordered and how they can offer treatment options which will improve your childrsquos wellbeing

ICD 9 Code VS DSM4R VS IFPIEP

Autismrsquos presentation of external behaviors are the result of internal physiology

Our presentation will focus on how the behaviors correlate with physical issues

Attempt to see all behaviors your child has as a means of communication of hisher physical self

Refrigerator Mothers poor parenting Purely a genetic disorder Hardwired malfunction of the brain Life long condition with no cure Diagnosis based on symptoms Treatment - one size fits all Medical treatment involves psychotropic drugs

with potential serious side effects

ldquoTreating autism with psychotropic meds is like treating a brain tumor with Motrinrdquo

Latest US statistics 1 in 150 children Genetic Epidemic What is causing the Rise in Autism Is Autism really that difficult to diagnose Where are all the autistic adults Why are so many kids sick What is happening to our environment that is

triggering this epidemic What does the future hold for our patients families

communities What will happen if we do not acknowledge this

epidemic What is the impact of every child that doesnrsquot

recover

WE NEED SOLUTIONS NOWWE NEED TO ACT NOW

httpwwwnindsnihgovdisordersautismdetail_autismhtm133913082

How is autism treated There is no cure for autism Therapies and behavioral interventions are

designed to remedy specific symptoms and can bring about substantial improvement The ideal treatment plan coordinates therapies and interventions that target the core symptoms of autism impaired social interaction problems with verbal and nonverbal communication and obsessive or repetitive routines and interests Most professionals agree that the earlier the intervention the better

Educationalbehavioral interventions Therapists use highly structured and intensive skill-oriented training sessions to help children develop social and language skills Family counseling for the parents and siblings of children with autism often helps families cope with the particular challenges of living with an autistic child

Medications Doctors often prescribe an antidepressant medication to handle symptoms of anxiety depression or obsessive-compulsive disorder Anti-psychotic medications are used to treat severe behavioral problems Seizures can be treated with one or more of the anticonvulsant drugs Stimulant drugs such as those used for children with attention deficit disorder (ADD) are sometimes used effectively to help decrease impulsivity and hyperactivity

Other therapies There are a number of controversial therapies or interventions available for autistic children but few if any are supported by scientific studies Parents should use caution before adopting any of these treatments

This presentation will review current labs ordered and how they can offer treatment options which will improve your childrsquos wellbeing

ICD 9 Code VS DSM4R VS IFPIEP

Autismrsquos presentation of external behaviors are the result of internal physiology

Our presentation will focus on how the behaviors correlate with physical issues

Attempt to see all behaviors your child has as a means of communication of hisher physical self

Refrigerator Mothers poor parenting Purely a genetic disorder Hardwired malfunction of the brain Life long condition with no cure Diagnosis based on symptoms Treatment - one size fits all Medical treatment involves psychotropic drugs

with potential serious side effects

ldquoTreating autism with psychotropic meds is like treating a brain tumor with Motrinrdquo

Latest US statistics 1 in 150 children Genetic Epidemic What is causing the Rise in Autism Is Autism really that difficult to diagnose Where are all the autistic adults Why are so many kids sick What is happening to our environment that is

triggering this epidemic What does the future hold for our patients families

communities What will happen if we do not acknowledge this

epidemic What is the impact of every child that doesnrsquot

recover

WE NEED SOLUTIONS NOWWE NEED TO ACT NOW

httpwwwnindsnihgovdisordersautismdetail_autismhtm133913082

How is autism treated There is no cure for autism Therapies and behavioral interventions are

designed to remedy specific symptoms and can bring about substantial improvement The ideal treatment plan coordinates therapies and interventions that target the core symptoms of autism impaired social interaction problems with verbal and nonverbal communication and obsessive or repetitive routines and interests Most professionals agree that the earlier the intervention the better

Educationalbehavioral interventions Therapists use highly structured and intensive skill-oriented training sessions to help children develop social and language skills Family counseling for the parents and siblings of children with autism often helps families cope with the particular challenges of living with an autistic child

Medications Doctors often prescribe an antidepressant medication to handle symptoms of anxiety depression or obsessive-compulsive disorder Anti-psychotic medications are used to treat severe behavioral problems Seizures can be treated with one or more of the anticonvulsant drugs Stimulant drugs such as those used for children with attention deficit disorder (ADD) are sometimes used effectively to help decrease impulsivity and hyperactivity

Other therapies There are a number of controversial therapies or interventions available for autistic children but few if any are supported by scientific studies Parents should use caution before adopting any of these treatments

ICD 9 Code VS DSM4R VS IFPIEP

Autismrsquos presentation of external behaviors are the result of internal physiology

Our presentation will focus on how the behaviors correlate with physical issues

Attempt to see all behaviors your child has as a means of communication of hisher physical self

Refrigerator Mothers poor parenting Purely a genetic disorder Hardwired malfunction of the brain Life long condition with no cure Diagnosis based on symptoms Treatment - one size fits all Medical treatment involves psychotropic drugs

with potential serious side effects

ldquoTreating autism with psychotropic meds is like treating a brain tumor with Motrinrdquo

Latest US statistics 1 in 150 children Genetic Epidemic What is causing the Rise in Autism Is Autism really that difficult to diagnose Where are all the autistic adults Why are so many kids sick What is happening to our environment that is

triggering this epidemic What does the future hold for our patients families

communities What will happen if we do not acknowledge this

epidemic What is the impact of every child that doesnrsquot

recover

WE NEED SOLUTIONS NOWWE NEED TO ACT NOW

httpwwwnindsnihgovdisordersautismdetail_autismhtm133913082

How is autism treated There is no cure for autism Therapies and behavioral interventions are

designed to remedy specific symptoms and can bring about substantial improvement The ideal treatment plan coordinates therapies and interventions that target the core symptoms of autism impaired social interaction problems with verbal and nonverbal communication and obsessive or repetitive routines and interests Most professionals agree that the earlier the intervention the better

Educationalbehavioral interventions Therapists use highly structured and intensive skill-oriented training sessions to help children develop social and language skills Family counseling for the parents and siblings of children with autism often helps families cope with the particular challenges of living with an autistic child

Medications Doctors often prescribe an antidepressant medication to handle symptoms of anxiety depression or obsessive-compulsive disorder Anti-psychotic medications are used to treat severe behavioral problems Seizures can be treated with one or more of the anticonvulsant drugs Stimulant drugs such as those used for children with attention deficit disorder (ADD) are sometimes used effectively to help decrease impulsivity and hyperactivity

Other therapies There are a number of controversial therapies or interventions available for autistic children but few if any are supported by scientific studies Parents should use caution before adopting any of these treatments

Refrigerator Mothers poor parenting Purely a genetic disorder Hardwired malfunction of the brain Life long condition with no cure Diagnosis based on symptoms Treatment - one size fits all Medical treatment involves psychotropic drugs

with potential serious side effects

ldquoTreating autism with psychotropic meds is like treating a brain tumor with Motrinrdquo

Latest US statistics 1 in 150 children Genetic Epidemic What is causing the Rise in Autism Is Autism really that difficult to diagnose Where are all the autistic adults Why are so many kids sick What is happening to our environment that is

triggering this epidemic What does the future hold for our patients families

communities What will happen if we do not acknowledge this

epidemic What is the impact of every child that doesnrsquot

recover

WE NEED SOLUTIONS NOWWE NEED TO ACT NOW

httpwwwnindsnihgovdisordersautismdetail_autismhtm133913082

How is autism treated There is no cure for autism Therapies and behavioral interventions are

designed to remedy specific symptoms and can bring about substantial improvement The ideal treatment plan coordinates therapies and interventions that target the core symptoms of autism impaired social interaction problems with verbal and nonverbal communication and obsessive or repetitive routines and interests Most professionals agree that the earlier the intervention the better

Educationalbehavioral interventions Therapists use highly structured and intensive skill-oriented training sessions to help children develop social and language skills Family counseling for the parents and siblings of children with autism often helps families cope with the particular challenges of living with an autistic child

Medications Doctors often prescribe an antidepressant medication to handle symptoms of anxiety depression or obsessive-compulsive disorder Anti-psychotic medications are used to treat severe behavioral problems Seizures can be treated with one or more of the anticonvulsant drugs Stimulant drugs such as those used for children with attention deficit disorder (ADD) are sometimes used effectively to help decrease impulsivity and hyperactivity

Other therapies There are a number of controversial therapies or interventions available for autistic children but few if any are supported by scientific studies Parents should use caution before adopting any of these treatments

Latest US statistics 1 in 150 children Genetic Epidemic What is causing the Rise in Autism Is Autism really that difficult to diagnose Where are all the autistic adults Why are so many kids sick What is happening to our environment that is

triggering this epidemic What does the future hold for our patients families

communities What will happen if we do not acknowledge this

epidemic What is the impact of every child that doesnrsquot

recover

WE NEED SOLUTIONS NOWWE NEED TO ACT NOW

httpwwwnindsnihgovdisordersautismdetail_autismhtm133913082

How is autism treated There is no cure for autism Therapies and behavioral interventions are

designed to remedy specific symptoms and can bring about substantial improvement The ideal treatment plan coordinates therapies and interventions that target the core symptoms of autism impaired social interaction problems with verbal and nonverbal communication and obsessive or repetitive routines and interests Most professionals agree that the earlier the intervention the better

Educationalbehavioral interventions Therapists use highly structured and intensive skill-oriented training sessions to help children develop social and language skills Family counseling for the parents and siblings of children with autism often helps families cope with the particular challenges of living with an autistic child

Medications Doctors often prescribe an antidepressant medication to handle symptoms of anxiety depression or obsessive-compulsive disorder Anti-psychotic medications are used to treat severe behavioral problems Seizures can be treated with one or more of the anticonvulsant drugs Stimulant drugs such as those used for children with attention deficit disorder (ADD) are sometimes used effectively to help decrease impulsivity and hyperactivity

Other therapies There are a number of controversial therapies or interventions available for autistic children but few if any are supported by scientific studies Parents should use caution before adopting any of these treatments

httpwwwnindsnihgovdisordersautismdetail_autismhtm133913082

How is autism treated There is no cure for autism Therapies and behavioral interventions are

designed to remedy specific symptoms and can bring about substantial improvement The ideal treatment plan coordinates therapies and interventions that target the core symptoms of autism impaired social interaction problems with verbal and nonverbal communication and obsessive or repetitive routines and interests Most professionals agree that the earlier the intervention the better

Educationalbehavioral interventions Therapists use highly structured and intensive skill-oriented training sessions to help children develop social and language skills Family counseling for the parents and siblings of children with autism often helps families cope with the particular challenges of living with an autistic child

Medications Doctors often prescribe an antidepressant medication to handle symptoms of anxiety depression or obsessive-compulsive disorder Anti-psychotic medications are used to treat severe behavioral problems Seizures can be treated with one or more of the anticonvulsant drugs Stimulant drugs such as those used for children with attention deficit disorder (ADD) are sometimes used effectively to help decrease impulsivity and hyperactivity

Other therapies There are a number of controversial therapies or interventions available for autistic children but few if any are supported by scientific studies Parents should use caution before adopting any of these treatments

Traditional Approach DiagnosisDisease

Based Subjective DSM IV-R criteria Lack of objective

findings Lack of unifying

framework Current research

focuses on improving diagnosis and classification

Research impaired Classification provides

management strategies

Mental Disorder Genetic Not covered by

medical insurance ICD 9 2990

Biomedical ModelIndividualPatient Based

Symptoms and Objective physical and chemical findings

Biochemical Metabolic Immunologic and Gastrointestinal Abnormalities

Unifying framework Research based on

treatment options Treatment is individualized

Medical Illness Genetics and

Environment define disorder (epigenetics)

Not covered by medical insurance

Numerous Diagnositic Codes

1 of 150 kids have autism Children that have recovered actually

had a diagnosis of Autism It is unethical to withhold medical

treatment for a medical condition Keeping autism solely as a behavioral

disorder allows medical treatment to be denied and overlooked

29900 = Current ICD9 diagnosis code for Autism(not reimbursable by insurance as a medical code because autism is a behavioral disorder and is not a medical condition)

httpwwwtalkaboutcuringautismorghealth-insurancehealth_ins_reimbursement_tipshtmLook at your child as having physical issues

that impact their behavior relay this to others

ie Make a list of these physical conditions

1 of 150 kids have autism Children that have recovered actually

had a diagnosis of Autism It is unethical to withhold medical

treatment for a medical condition Keeping autism solely as a behavioral

disorder allows medical treatment to be denied and overlooked

29900 = Current ICD9 diagnosis code for Autism(not reimbursable by insurance as a medical code because autism is a behavioral disorder and is not a medical condition)

httpwwwtalkaboutcuringautismorghealth-insurancehealth_ins_reimbursement_tipshtmLook at your child as having physical issues

that impact their behavior relay this to others

ie Make a list of these physical conditions

29900 = Current ICD9 diagnosis code for Autism(not reimbursable by insurance as a medical code because autism is a behavioral disorder and is not a medical condition)

httpwwwtalkaboutcuringautismorghealth-insurancehealth_ins_reimbursement_tipshtmLook at your child as having physical issues

that impact their behavior relay this to others

ie Make a list of these physical conditions

Lost weight Slow growth as seen on his growth chartDeclining well beingThinning hairLoss of speechSweaty headConstipatedHand posturingPale complexionPoor sleepSour breathFrequent night waking Picky eatingPoor fine motor controlPoor muscle coordination

Above list of symptoms Diagnosis= Autism

I disagree my son is not Autistic he is SICK

bull Founder bull Autism Research Institute (ASI)bull Autism Society of America (ASA)bull Scientific Basis of the Biomedical Approachbull Studies of High Dosage Vitamin B6 and Magnesium in

Autistic Children and Adults 1965 - 2005bull wwwautismwebsitecomARItreatmentb6studieshtm

bull Twenty-one of twenty-two studies yielded positive results including 13 double-blind placebo-controlled trials even minor adverse effects rarely were seen

bullDr Bernie Rimland

bull Founder bull Autism Research Institute (ASI)bull Autism Society of America (ASA)bull Scientific Basis of the Biomedical Approachbull Studies of High Dosage Vitamin B6 and Magnesium in

Autistic Children and Adults 1965 - 2005bull wwwautismwebsitecomARItreatmentb6studieshtm

bull Twenty-one of twenty-two studies yielded positive results including 13 double-blind placebo-controlled trials even minor adverse effects rarely were seen

bullDr Bernie Rimland

bull Founders of DAN- Dr Baker and Dr Pangbornbull Combined effort of Parents Physicians and Researchersbull Autism Effective Biomedical Treatments bull Jon Pangborn PhD and Sidney M Baker MD

bull Oct 2005 this manual revolutionized the biomedical approach in the treatment of autism PDD and related disorders

bull Defeat Autism Now Consensus Reportbull Defeat Autism Now Think Tankbull Defeat Autism Now Conferencebull Recovered Kids ndash thousands of cases documented

bull Compilation of Studies Supporting the Biomedical Approach wwwautismwebsitecomARIdanscientificfoundationshtm

bullThe DAN (Defeat Autism Now) Approach

This is one picture with two animals represented at the same time Autism is both physical and behavioral

You are the Coach assemble your team players

Sometimes the team players need to be traded

Educate the professional team players about your childrsquos physical condition writing down specifics

Write down a concernobservation Ask yourself specific questions

When does this behavior happen What occurs before I see this behavior What did heshe eat today Are there any signs of pain What happens after you intervene

Our practice currently treats over 1500 children world wide

Our patients have physical issues that impact their physical well being

Assessment and treatment of their physical well being brings around a positive change in that childs life

bullEnvironmental ToxicitybullAnd Heavy Metal Burden

bullGenetics

bullBiologic and bullImmunological bullTriggers

bullAutism

bullTiming

bullCausation Theories andbull the Web of Interactions

bullHeavy Metal OverloadbullOxidative StressbullMitochondrial DysfunctionbullGut AbnormalitiesbullImmune DysregulationbullChronic Inflammation

History and Physical Examination Laboratory Testing Clean Up

Environmental Controls Dietary Interventions Address Gastrointestinal Health

Foundational Nutrients Support underlying Immune Issues

and Inflammation Support MethylationGlutathione

Pathways Heavy Metal Detoxification Hyperbaric Oxygen Therapy

Educational and Behavioral TherapiesEducational and Behavioral Therapies

Environmental ControlsEnvironmental Controls

Dietary InterventionsDietary Interventions

Nutrient TherapiesNutrient Therapies

Gastrointestinal HealthGastrointestinal Health

Immune Issues and InflammationImmune Issues and Inflammation

Promotion of Natural Methylation and Glutathione ProductionPromotion of Natural Methylation and Glutathione Production

Pharmaceutical Chelation and other Drug therapyPharmaceutical Chelation and other Drug therapy

Hyperbaric Oxygen TherapyHyperbaric Oxygen Therapy

bullIntensity of Symptoms = Intensity of Treatment

Basic Labs CBC with

differential Comprehensive

Metabolic Panel Iron and Ferritin

Level Thyroid panel Blood Lead level Plasma Zinc Vitamin D 25 OH Blood Ammonia Serum Copper

Reasons to run labs Weight loss Frequent infections Pica Poor attention Hyperactivity Picky eater Maldigestion Malabsorption Poor Growth

CBC Comprehensive Metabolic Panel Serum Copper Plasma Zinc Hair Analysis Thyroid profile Blood Lead Ammonia

Intracellular Minerals and Metals Urine Essential Minerals Essential Fatty Acids Plasma or Urine Amino Acids Plasma cysteine sulfate rGSH

Urine Organic Acids Stool Microbiology Stool Mycology Stool Parasitology Celiac Panel IgG IgE Allergy Panels

Immune Markers Immunoglobulin Levels (IgG IgA

IgM) T lymphocyte Panel (CD4 CD8) Natural Killer Cell Activity PANDArsquos Profile Anti MBP Ab Anti NAFP Ab IgG Food Ab Panel Vaccine Titers Viral Titers

Urinary Peptides Hormone Studies Neurotransmitter Levels Genomics ndash SNPs

Urine Fecal Toxic Metals Urinary Porphryins Urinary Neopterin Urinary 8-OH Guanosine Isoprostane Organophosphate Levels Mitochondrial Markers

Ammonia Pyruvate Lactic Acid Carnitine Panel

bull21

Th1 and Th2 skewing Abnormal cell-mediated immunity (Molloy 2006) Abnormal T-cell subsets decreased NK cells abnormal

cytokines Th2 skewing (Zimmerman 1998 Gupta 1996) Decreased secretory IgA Pro-inflammatory cytokinesTNF alpha IL-6 (Jyonuchi 2001

Maes 2001) Mercury Lead and Aluminum cause Th1Th2 skewed immune

system

Pro-inflammatory Cytokines in the Brain MCP-1 TGF beta-1 (Vargas Pardo Laurence 2005) Abnormal EEG Seizure activity Microglial Activation (Vargas Pardo 2005)

Increased Autoimmunity Autoantibodies to neural antigens (Connolly 1999) Mylein basic protein and Neuronal Axonal Filament Protein

Antibodies (Gupta 1996 Singh 1997)

Children absorb Pb more readily than adults Fluoride increases Pb absorption Lead burden can cause learning disability

ADD hyperactivity deliquency Synergy with Mercury increases toxicity

exponentially Safe threshold changed from 60ugdl to

10ugdl Children with blood levels of 10 mcgdl the

upper limit of the ldquosafe rangerdquo have IQs 75 points below those of kids whose blood Pb levels are 0-1mcgdl

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

You are the Coach assemble your team players

Sometimes the team players need to be traded

Educate the professional team players about your childrsquos physical condition writing down specifics

Write down a concernobservation Ask yourself specific questions

When does this behavior happen What occurs before I see this behavior What did heshe eat today Are there any signs of pain What happens after you intervene

Our practice currently treats over 1500 children world wide

Our patients have physical issues that impact their physical well being

Assessment and treatment of their physical well being brings around a positive change in that childs life

bullEnvironmental ToxicitybullAnd Heavy Metal Burden

bullGenetics

bullBiologic and bullImmunological bullTriggers

bullAutism

bullTiming

bullCausation Theories andbull the Web of Interactions

bullHeavy Metal OverloadbullOxidative StressbullMitochondrial DysfunctionbullGut AbnormalitiesbullImmune DysregulationbullChronic Inflammation

History and Physical Examination Laboratory Testing Clean Up

Environmental Controls Dietary Interventions Address Gastrointestinal Health

Foundational Nutrients Support underlying Immune Issues

and Inflammation Support MethylationGlutathione

Pathways Heavy Metal Detoxification Hyperbaric Oxygen Therapy

Educational and Behavioral TherapiesEducational and Behavioral Therapies

Environmental ControlsEnvironmental Controls

Dietary InterventionsDietary Interventions

Nutrient TherapiesNutrient Therapies

Gastrointestinal HealthGastrointestinal Health

Immune Issues and InflammationImmune Issues and Inflammation

Promotion of Natural Methylation and Glutathione ProductionPromotion of Natural Methylation and Glutathione Production

Pharmaceutical Chelation and other Drug therapyPharmaceutical Chelation and other Drug therapy

Hyperbaric Oxygen TherapyHyperbaric Oxygen Therapy

bullIntensity of Symptoms = Intensity of Treatment

Basic Labs CBC with

differential Comprehensive

Metabolic Panel Iron and Ferritin

Level Thyroid panel Blood Lead level Plasma Zinc Vitamin D 25 OH Blood Ammonia Serum Copper

Reasons to run labs Weight loss Frequent infections Pica Poor attention Hyperactivity Picky eater Maldigestion Malabsorption Poor Growth

CBC Comprehensive Metabolic Panel Serum Copper Plasma Zinc Hair Analysis Thyroid profile Blood Lead Ammonia

Intracellular Minerals and Metals Urine Essential Minerals Essential Fatty Acids Plasma or Urine Amino Acids Plasma cysteine sulfate rGSH

Urine Organic Acids Stool Microbiology Stool Mycology Stool Parasitology Celiac Panel IgG IgE Allergy Panels

Immune Markers Immunoglobulin Levels (IgG IgA

IgM) T lymphocyte Panel (CD4 CD8) Natural Killer Cell Activity PANDArsquos Profile Anti MBP Ab Anti NAFP Ab IgG Food Ab Panel Vaccine Titers Viral Titers

Urinary Peptides Hormone Studies Neurotransmitter Levels Genomics ndash SNPs

Urine Fecal Toxic Metals Urinary Porphryins Urinary Neopterin Urinary 8-OH Guanosine Isoprostane Organophosphate Levels Mitochondrial Markers

Ammonia Pyruvate Lactic Acid Carnitine Panel

bull21

Th1 and Th2 skewing Abnormal cell-mediated immunity (Molloy 2006) Abnormal T-cell subsets decreased NK cells abnormal

cytokines Th2 skewing (Zimmerman 1998 Gupta 1996) Decreased secretory IgA Pro-inflammatory cytokinesTNF alpha IL-6 (Jyonuchi 2001

Maes 2001) Mercury Lead and Aluminum cause Th1Th2 skewed immune

system

Pro-inflammatory Cytokines in the Brain MCP-1 TGF beta-1 (Vargas Pardo Laurence 2005) Abnormal EEG Seizure activity Microglial Activation (Vargas Pardo 2005)

Increased Autoimmunity Autoantibodies to neural antigens (Connolly 1999) Mylein basic protein and Neuronal Axonal Filament Protein

Antibodies (Gupta 1996 Singh 1997)

Children absorb Pb more readily than adults Fluoride increases Pb absorption Lead burden can cause learning disability

ADD hyperactivity deliquency Synergy with Mercury increases toxicity

exponentially Safe threshold changed from 60ugdl to

10ugdl Children with blood levels of 10 mcgdl the

upper limit of the ldquosafe rangerdquo have IQs 75 points below those of kids whose blood Pb levels are 0-1mcgdl

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Write down a concernobservation Ask yourself specific questions

When does this behavior happen What occurs before I see this behavior What did heshe eat today Are there any signs of pain What happens after you intervene

Our practice currently treats over 1500 children world wide

Our patients have physical issues that impact their physical well being

Assessment and treatment of their physical well being brings around a positive change in that childs life

bullEnvironmental ToxicitybullAnd Heavy Metal Burden

bullGenetics

bullBiologic and bullImmunological bullTriggers

bullAutism

bullTiming

bullCausation Theories andbull the Web of Interactions

bullHeavy Metal OverloadbullOxidative StressbullMitochondrial DysfunctionbullGut AbnormalitiesbullImmune DysregulationbullChronic Inflammation

History and Physical Examination Laboratory Testing Clean Up

Environmental Controls Dietary Interventions Address Gastrointestinal Health

Foundational Nutrients Support underlying Immune Issues

and Inflammation Support MethylationGlutathione

Pathways Heavy Metal Detoxification Hyperbaric Oxygen Therapy

Educational and Behavioral TherapiesEducational and Behavioral Therapies

Environmental ControlsEnvironmental Controls

Dietary InterventionsDietary Interventions

Nutrient TherapiesNutrient Therapies

Gastrointestinal HealthGastrointestinal Health

Immune Issues and InflammationImmune Issues and Inflammation

Promotion of Natural Methylation and Glutathione ProductionPromotion of Natural Methylation and Glutathione Production

Pharmaceutical Chelation and other Drug therapyPharmaceutical Chelation and other Drug therapy

Hyperbaric Oxygen TherapyHyperbaric Oxygen Therapy

bullIntensity of Symptoms = Intensity of Treatment

Basic Labs CBC with

differential Comprehensive

Metabolic Panel Iron and Ferritin

Level Thyroid panel Blood Lead level Plasma Zinc Vitamin D 25 OH Blood Ammonia Serum Copper

Reasons to run labs Weight loss Frequent infections Pica Poor attention Hyperactivity Picky eater Maldigestion Malabsorption Poor Growth

CBC Comprehensive Metabolic Panel Serum Copper Plasma Zinc Hair Analysis Thyroid profile Blood Lead Ammonia

Intracellular Minerals and Metals Urine Essential Minerals Essential Fatty Acids Plasma or Urine Amino Acids Plasma cysteine sulfate rGSH

Urine Organic Acids Stool Microbiology Stool Mycology Stool Parasitology Celiac Panel IgG IgE Allergy Panels

Immune Markers Immunoglobulin Levels (IgG IgA

IgM) T lymphocyte Panel (CD4 CD8) Natural Killer Cell Activity PANDArsquos Profile Anti MBP Ab Anti NAFP Ab IgG Food Ab Panel Vaccine Titers Viral Titers

Urinary Peptides Hormone Studies Neurotransmitter Levels Genomics ndash SNPs

Urine Fecal Toxic Metals Urinary Porphryins Urinary Neopterin Urinary 8-OH Guanosine Isoprostane Organophosphate Levels Mitochondrial Markers

Ammonia Pyruvate Lactic Acid Carnitine Panel

bull21

Th1 and Th2 skewing Abnormal cell-mediated immunity (Molloy 2006) Abnormal T-cell subsets decreased NK cells abnormal

cytokines Th2 skewing (Zimmerman 1998 Gupta 1996) Decreased secretory IgA Pro-inflammatory cytokinesTNF alpha IL-6 (Jyonuchi 2001

Maes 2001) Mercury Lead and Aluminum cause Th1Th2 skewed immune

system

Pro-inflammatory Cytokines in the Brain MCP-1 TGF beta-1 (Vargas Pardo Laurence 2005) Abnormal EEG Seizure activity Microglial Activation (Vargas Pardo 2005)

Increased Autoimmunity Autoantibodies to neural antigens (Connolly 1999) Mylein basic protein and Neuronal Axonal Filament Protein

Antibodies (Gupta 1996 Singh 1997)

Children absorb Pb more readily than adults Fluoride increases Pb absorption Lead burden can cause learning disability

ADD hyperactivity deliquency Synergy with Mercury increases toxicity

exponentially Safe threshold changed from 60ugdl to

10ugdl Children with blood levels of 10 mcgdl the

upper limit of the ldquosafe rangerdquo have IQs 75 points below those of kids whose blood Pb levels are 0-1mcgdl

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Our practice currently treats over 1500 children world wide

Our patients have physical issues that impact their physical well being

Assessment and treatment of their physical well being brings around a positive change in that childs life

bullEnvironmental ToxicitybullAnd Heavy Metal Burden

bullGenetics

bullBiologic and bullImmunological bullTriggers

bullAutism

bullTiming

bullCausation Theories andbull the Web of Interactions

bullHeavy Metal OverloadbullOxidative StressbullMitochondrial DysfunctionbullGut AbnormalitiesbullImmune DysregulationbullChronic Inflammation

History and Physical Examination Laboratory Testing Clean Up

Environmental Controls Dietary Interventions Address Gastrointestinal Health

Foundational Nutrients Support underlying Immune Issues

and Inflammation Support MethylationGlutathione

Pathways Heavy Metal Detoxification Hyperbaric Oxygen Therapy

Educational and Behavioral TherapiesEducational and Behavioral Therapies

Environmental ControlsEnvironmental Controls

Dietary InterventionsDietary Interventions

Nutrient TherapiesNutrient Therapies

Gastrointestinal HealthGastrointestinal Health

Immune Issues and InflammationImmune Issues and Inflammation

Promotion of Natural Methylation and Glutathione ProductionPromotion of Natural Methylation and Glutathione Production

Pharmaceutical Chelation and other Drug therapyPharmaceutical Chelation and other Drug therapy

Hyperbaric Oxygen TherapyHyperbaric Oxygen Therapy

bullIntensity of Symptoms = Intensity of Treatment

Basic Labs CBC with

differential Comprehensive

Metabolic Panel Iron and Ferritin

Level Thyroid panel Blood Lead level Plasma Zinc Vitamin D 25 OH Blood Ammonia Serum Copper

Reasons to run labs Weight loss Frequent infections Pica Poor attention Hyperactivity Picky eater Maldigestion Malabsorption Poor Growth

CBC Comprehensive Metabolic Panel Serum Copper Plasma Zinc Hair Analysis Thyroid profile Blood Lead Ammonia

Intracellular Minerals and Metals Urine Essential Minerals Essential Fatty Acids Plasma or Urine Amino Acids Plasma cysteine sulfate rGSH

Urine Organic Acids Stool Microbiology Stool Mycology Stool Parasitology Celiac Panel IgG IgE Allergy Panels

Immune Markers Immunoglobulin Levels (IgG IgA

IgM) T lymphocyte Panel (CD4 CD8) Natural Killer Cell Activity PANDArsquos Profile Anti MBP Ab Anti NAFP Ab IgG Food Ab Panel Vaccine Titers Viral Titers

Urinary Peptides Hormone Studies Neurotransmitter Levels Genomics ndash SNPs

Urine Fecal Toxic Metals Urinary Porphryins Urinary Neopterin Urinary 8-OH Guanosine Isoprostane Organophosphate Levels Mitochondrial Markers

Ammonia Pyruvate Lactic Acid Carnitine Panel

bull21

Th1 and Th2 skewing Abnormal cell-mediated immunity (Molloy 2006) Abnormal T-cell subsets decreased NK cells abnormal

cytokines Th2 skewing (Zimmerman 1998 Gupta 1996) Decreased secretory IgA Pro-inflammatory cytokinesTNF alpha IL-6 (Jyonuchi 2001

Maes 2001) Mercury Lead and Aluminum cause Th1Th2 skewed immune

system

Pro-inflammatory Cytokines in the Brain MCP-1 TGF beta-1 (Vargas Pardo Laurence 2005) Abnormal EEG Seizure activity Microglial Activation (Vargas Pardo 2005)

Increased Autoimmunity Autoantibodies to neural antigens (Connolly 1999) Mylein basic protein and Neuronal Axonal Filament Protein

Antibodies (Gupta 1996 Singh 1997)

Children absorb Pb more readily than adults Fluoride increases Pb absorption Lead burden can cause learning disability

ADD hyperactivity deliquency Synergy with Mercury increases toxicity

exponentially Safe threshold changed from 60ugdl to

10ugdl Children with blood levels of 10 mcgdl the

upper limit of the ldquosafe rangerdquo have IQs 75 points below those of kids whose blood Pb levels are 0-1mcgdl

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

bullEnvironmental ToxicitybullAnd Heavy Metal Burden

bullGenetics

bullBiologic and bullImmunological bullTriggers

bullAutism

bullTiming

bullCausation Theories andbull the Web of Interactions

bullHeavy Metal OverloadbullOxidative StressbullMitochondrial DysfunctionbullGut AbnormalitiesbullImmune DysregulationbullChronic Inflammation

History and Physical Examination Laboratory Testing Clean Up

Environmental Controls Dietary Interventions Address Gastrointestinal Health

Foundational Nutrients Support underlying Immune Issues

and Inflammation Support MethylationGlutathione

Pathways Heavy Metal Detoxification Hyperbaric Oxygen Therapy

Educational and Behavioral TherapiesEducational and Behavioral Therapies

Environmental ControlsEnvironmental Controls

Dietary InterventionsDietary Interventions

Nutrient TherapiesNutrient Therapies

Gastrointestinal HealthGastrointestinal Health

Immune Issues and InflammationImmune Issues and Inflammation

Promotion of Natural Methylation and Glutathione ProductionPromotion of Natural Methylation and Glutathione Production

Pharmaceutical Chelation and other Drug therapyPharmaceutical Chelation and other Drug therapy

Hyperbaric Oxygen TherapyHyperbaric Oxygen Therapy

bullIntensity of Symptoms = Intensity of Treatment

Basic Labs CBC with

differential Comprehensive

Metabolic Panel Iron and Ferritin

Level Thyroid panel Blood Lead level Plasma Zinc Vitamin D 25 OH Blood Ammonia Serum Copper

Reasons to run labs Weight loss Frequent infections Pica Poor attention Hyperactivity Picky eater Maldigestion Malabsorption Poor Growth

CBC Comprehensive Metabolic Panel Serum Copper Plasma Zinc Hair Analysis Thyroid profile Blood Lead Ammonia

Intracellular Minerals and Metals Urine Essential Minerals Essential Fatty Acids Plasma or Urine Amino Acids Plasma cysteine sulfate rGSH

Urine Organic Acids Stool Microbiology Stool Mycology Stool Parasitology Celiac Panel IgG IgE Allergy Panels

Immune Markers Immunoglobulin Levels (IgG IgA

IgM) T lymphocyte Panel (CD4 CD8) Natural Killer Cell Activity PANDArsquos Profile Anti MBP Ab Anti NAFP Ab IgG Food Ab Panel Vaccine Titers Viral Titers

Urinary Peptides Hormone Studies Neurotransmitter Levels Genomics ndash SNPs

Urine Fecal Toxic Metals Urinary Porphryins Urinary Neopterin Urinary 8-OH Guanosine Isoprostane Organophosphate Levels Mitochondrial Markers

Ammonia Pyruvate Lactic Acid Carnitine Panel

bull21

Th1 and Th2 skewing Abnormal cell-mediated immunity (Molloy 2006) Abnormal T-cell subsets decreased NK cells abnormal

cytokines Th2 skewing (Zimmerman 1998 Gupta 1996) Decreased secretory IgA Pro-inflammatory cytokinesTNF alpha IL-6 (Jyonuchi 2001

Maes 2001) Mercury Lead and Aluminum cause Th1Th2 skewed immune

system

Pro-inflammatory Cytokines in the Brain MCP-1 TGF beta-1 (Vargas Pardo Laurence 2005) Abnormal EEG Seizure activity Microglial Activation (Vargas Pardo 2005)

Increased Autoimmunity Autoantibodies to neural antigens (Connolly 1999) Mylein basic protein and Neuronal Axonal Filament Protein

Antibodies (Gupta 1996 Singh 1997)

Children absorb Pb more readily than adults Fluoride increases Pb absorption Lead burden can cause learning disability

ADD hyperactivity deliquency Synergy with Mercury increases toxicity

exponentially Safe threshold changed from 60ugdl to

10ugdl Children with blood levels of 10 mcgdl the

upper limit of the ldquosafe rangerdquo have IQs 75 points below those of kids whose blood Pb levels are 0-1mcgdl

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

History and Physical Examination Laboratory Testing Clean Up

Environmental Controls Dietary Interventions Address Gastrointestinal Health

Foundational Nutrients Support underlying Immune Issues

and Inflammation Support MethylationGlutathione

Pathways Heavy Metal Detoxification Hyperbaric Oxygen Therapy

Educational and Behavioral TherapiesEducational and Behavioral Therapies

Environmental ControlsEnvironmental Controls

Dietary InterventionsDietary Interventions

Nutrient TherapiesNutrient Therapies

Gastrointestinal HealthGastrointestinal Health

Immune Issues and InflammationImmune Issues and Inflammation

Promotion of Natural Methylation and Glutathione ProductionPromotion of Natural Methylation and Glutathione Production

Pharmaceutical Chelation and other Drug therapyPharmaceutical Chelation and other Drug therapy

Hyperbaric Oxygen TherapyHyperbaric Oxygen Therapy

bullIntensity of Symptoms = Intensity of Treatment

Basic Labs CBC with

differential Comprehensive

Metabolic Panel Iron and Ferritin

Level Thyroid panel Blood Lead level Plasma Zinc Vitamin D 25 OH Blood Ammonia Serum Copper

Reasons to run labs Weight loss Frequent infections Pica Poor attention Hyperactivity Picky eater Maldigestion Malabsorption Poor Growth

CBC Comprehensive Metabolic Panel Serum Copper Plasma Zinc Hair Analysis Thyroid profile Blood Lead Ammonia

Intracellular Minerals and Metals Urine Essential Minerals Essential Fatty Acids Plasma or Urine Amino Acids Plasma cysteine sulfate rGSH

Urine Organic Acids Stool Microbiology Stool Mycology Stool Parasitology Celiac Panel IgG IgE Allergy Panels

Immune Markers Immunoglobulin Levels (IgG IgA

IgM) T lymphocyte Panel (CD4 CD8) Natural Killer Cell Activity PANDArsquos Profile Anti MBP Ab Anti NAFP Ab IgG Food Ab Panel Vaccine Titers Viral Titers

Urinary Peptides Hormone Studies Neurotransmitter Levels Genomics ndash SNPs

Urine Fecal Toxic Metals Urinary Porphryins Urinary Neopterin Urinary 8-OH Guanosine Isoprostane Organophosphate Levels Mitochondrial Markers

Ammonia Pyruvate Lactic Acid Carnitine Panel

bull21

Th1 and Th2 skewing Abnormal cell-mediated immunity (Molloy 2006) Abnormal T-cell subsets decreased NK cells abnormal

cytokines Th2 skewing (Zimmerman 1998 Gupta 1996) Decreased secretory IgA Pro-inflammatory cytokinesTNF alpha IL-6 (Jyonuchi 2001

Maes 2001) Mercury Lead and Aluminum cause Th1Th2 skewed immune

system

Pro-inflammatory Cytokines in the Brain MCP-1 TGF beta-1 (Vargas Pardo Laurence 2005) Abnormal EEG Seizure activity Microglial Activation (Vargas Pardo 2005)

Increased Autoimmunity Autoantibodies to neural antigens (Connolly 1999) Mylein basic protein and Neuronal Axonal Filament Protein

Antibodies (Gupta 1996 Singh 1997)

Children absorb Pb more readily than adults Fluoride increases Pb absorption Lead burden can cause learning disability

ADD hyperactivity deliquency Synergy with Mercury increases toxicity

exponentially Safe threshold changed from 60ugdl to

10ugdl Children with blood levels of 10 mcgdl the

upper limit of the ldquosafe rangerdquo have IQs 75 points below those of kids whose blood Pb levels are 0-1mcgdl

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Educational and Behavioral TherapiesEducational and Behavioral Therapies

Environmental ControlsEnvironmental Controls

Dietary InterventionsDietary Interventions

Nutrient TherapiesNutrient Therapies

Gastrointestinal HealthGastrointestinal Health

Immune Issues and InflammationImmune Issues and Inflammation

Promotion of Natural Methylation and Glutathione ProductionPromotion of Natural Methylation and Glutathione Production

Pharmaceutical Chelation and other Drug therapyPharmaceutical Chelation and other Drug therapy

Hyperbaric Oxygen TherapyHyperbaric Oxygen Therapy

bullIntensity of Symptoms = Intensity of Treatment

Basic Labs CBC with

differential Comprehensive

Metabolic Panel Iron and Ferritin

Level Thyroid panel Blood Lead level Plasma Zinc Vitamin D 25 OH Blood Ammonia Serum Copper

Reasons to run labs Weight loss Frequent infections Pica Poor attention Hyperactivity Picky eater Maldigestion Malabsorption Poor Growth

CBC Comprehensive Metabolic Panel Serum Copper Plasma Zinc Hair Analysis Thyroid profile Blood Lead Ammonia

Intracellular Minerals and Metals Urine Essential Minerals Essential Fatty Acids Plasma or Urine Amino Acids Plasma cysteine sulfate rGSH

Urine Organic Acids Stool Microbiology Stool Mycology Stool Parasitology Celiac Panel IgG IgE Allergy Panels

Immune Markers Immunoglobulin Levels (IgG IgA

IgM) T lymphocyte Panel (CD4 CD8) Natural Killer Cell Activity PANDArsquos Profile Anti MBP Ab Anti NAFP Ab IgG Food Ab Panel Vaccine Titers Viral Titers

Urinary Peptides Hormone Studies Neurotransmitter Levels Genomics ndash SNPs

Urine Fecal Toxic Metals Urinary Porphryins Urinary Neopterin Urinary 8-OH Guanosine Isoprostane Organophosphate Levels Mitochondrial Markers

Ammonia Pyruvate Lactic Acid Carnitine Panel

bull21

Th1 and Th2 skewing Abnormal cell-mediated immunity (Molloy 2006) Abnormal T-cell subsets decreased NK cells abnormal

cytokines Th2 skewing (Zimmerman 1998 Gupta 1996) Decreased secretory IgA Pro-inflammatory cytokinesTNF alpha IL-6 (Jyonuchi 2001

Maes 2001) Mercury Lead and Aluminum cause Th1Th2 skewed immune

system

Pro-inflammatory Cytokines in the Brain MCP-1 TGF beta-1 (Vargas Pardo Laurence 2005) Abnormal EEG Seizure activity Microglial Activation (Vargas Pardo 2005)

Increased Autoimmunity Autoantibodies to neural antigens (Connolly 1999) Mylein basic protein and Neuronal Axonal Filament Protein

Antibodies (Gupta 1996 Singh 1997)

Children absorb Pb more readily than adults Fluoride increases Pb absorption Lead burden can cause learning disability

ADD hyperactivity deliquency Synergy with Mercury increases toxicity

exponentially Safe threshold changed from 60ugdl to

10ugdl Children with blood levels of 10 mcgdl the

upper limit of the ldquosafe rangerdquo have IQs 75 points below those of kids whose blood Pb levels are 0-1mcgdl

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Basic Labs CBC with

differential Comprehensive

Metabolic Panel Iron and Ferritin

Level Thyroid panel Blood Lead level Plasma Zinc Vitamin D 25 OH Blood Ammonia Serum Copper

Reasons to run labs Weight loss Frequent infections Pica Poor attention Hyperactivity Picky eater Maldigestion Malabsorption Poor Growth

CBC Comprehensive Metabolic Panel Serum Copper Plasma Zinc Hair Analysis Thyroid profile Blood Lead Ammonia

Intracellular Minerals and Metals Urine Essential Minerals Essential Fatty Acids Plasma or Urine Amino Acids Plasma cysteine sulfate rGSH

Urine Organic Acids Stool Microbiology Stool Mycology Stool Parasitology Celiac Panel IgG IgE Allergy Panels

Immune Markers Immunoglobulin Levels (IgG IgA

IgM) T lymphocyte Panel (CD4 CD8) Natural Killer Cell Activity PANDArsquos Profile Anti MBP Ab Anti NAFP Ab IgG Food Ab Panel Vaccine Titers Viral Titers

Urinary Peptides Hormone Studies Neurotransmitter Levels Genomics ndash SNPs

Urine Fecal Toxic Metals Urinary Porphryins Urinary Neopterin Urinary 8-OH Guanosine Isoprostane Organophosphate Levels Mitochondrial Markers

Ammonia Pyruvate Lactic Acid Carnitine Panel

bull21

Th1 and Th2 skewing Abnormal cell-mediated immunity (Molloy 2006) Abnormal T-cell subsets decreased NK cells abnormal

cytokines Th2 skewing (Zimmerman 1998 Gupta 1996) Decreased secretory IgA Pro-inflammatory cytokinesTNF alpha IL-6 (Jyonuchi 2001

Maes 2001) Mercury Lead and Aluminum cause Th1Th2 skewed immune

system

Pro-inflammatory Cytokines in the Brain MCP-1 TGF beta-1 (Vargas Pardo Laurence 2005) Abnormal EEG Seizure activity Microglial Activation (Vargas Pardo 2005)

Increased Autoimmunity Autoantibodies to neural antigens (Connolly 1999) Mylein basic protein and Neuronal Axonal Filament Protein

Antibodies (Gupta 1996 Singh 1997)

Children absorb Pb more readily than adults Fluoride increases Pb absorption Lead burden can cause learning disability

ADD hyperactivity deliquency Synergy with Mercury increases toxicity

exponentially Safe threshold changed from 60ugdl to

10ugdl Children with blood levels of 10 mcgdl the

upper limit of the ldquosafe rangerdquo have IQs 75 points below those of kids whose blood Pb levels are 0-1mcgdl

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

CBC Comprehensive Metabolic Panel Serum Copper Plasma Zinc Hair Analysis Thyroid profile Blood Lead Ammonia

Intracellular Minerals and Metals Urine Essential Minerals Essential Fatty Acids Plasma or Urine Amino Acids Plasma cysteine sulfate rGSH

Urine Organic Acids Stool Microbiology Stool Mycology Stool Parasitology Celiac Panel IgG IgE Allergy Panels

Immune Markers Immunoglobulin Levels (IgG IgA

IgM) T lymphocyte Panel (CD4 CD8) Natural Killer Cell Activity PANDArsquos Profile Anti MBP Ab Anti NAFP Ab IgG Food Ab Panel Vaccine Titers Viral Titers

Urinary Peptides Hormone Studies Neurotransmitter Levels Genomics ndash SNPs

Urine Fecal Toxic Metals Urinary Porphryins Urinary Neopterin Urinary 8-OH Guanosine Isoprostane Organophosphate Levels Mitochondrial Markers

Ammonia Pyruvate Lactic Acid Carnitine Panel

bull21

Th1 and Th2 skewing Abnormal cell-mediated immunity (Molloy 2006) Abnormal T-cell subsets decreased NK cells abnormal

cytokines Th2 skewing (Zimmerman 1998 Gupta 1996) Decreased secretory IgA Pro-inflammatory cytokinesTNF alpha IL-6 (Jyonuchi 2001

Maes 2001) Mercury Lead and Aluminum cause Th1Th2 skewed immune

system

Pro-inflammatory Cytokines in the Brain MCP-1 TGF beta-1 (Vargas Pardo Laurence 2005) Abnormal EEG Seizure activity Microglial Activation (Vargas Pardo 2005)

Increased Autoimmunity Autoantibodies to neural antigens (Connolly 1999) Mylein basic protein and Neuronal Axonal Filament Protein

Antibodies (Gupta 1996 Singh 1997)

Children absorb Pb more readily than adults Fluoride increases Pb absorption Lead burden can cause learning disability

ADD hyperactivity deliquency Synergy with Mercury increases toxicity

exponentially Safe threshold changed from 60ugdl to

10ugdl Children with blood levels of 10 mcgdl the

upper limit of the ldquosafe rangerdquo have IQs 75 points below those of kids whose blood Pb levels are 0-1mcgdl

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Th1 and Th2 skewing Abnormal cell-mediated immunity (Molloy 2006) Abnormal T-cell subsets decreased NK cells abnormal

cytokines Th2 skewing (Zimmerman 1998 Gupta 1996) Decreased secretory IgA Pro-inflammatory cytokinesTNF alpha IL-6 (Jyonuchi 2001

Maes 2001) Mercury Lead and Aluminum cause Th1Th2 skewed immune

system

Pro-inflammatory Cytokines in the Brain MCP-1 TGF beta-1 (Vargas Pardo Laurence 2005) Abnormal EEG Seizure activity Microglial Activation (Vargas Pardo 2005)

Increased Autoimmunity Autoantibodies to neural antigens (Connolly 1999) Mylein basic protein and Neuronal Axonal Filament Protein

Antibodies (Gupta 1996 Singh 1997)

Children absorb Pb more readily than adults Fluoride increases Pb absorption Lead burden can cause learning disability

ADD hyperactivity deliquency Synergy with Mercury increases toxicity

exponentially Safe threshold changed from 60ugdl to

10ugdl Children with blood levels of 10 mcgdl the

upper limit of the ldquosafe rangerdquo have IQs 75 points below those of kids whose blood Pb levels are 0-1mcgdl

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Children absorb Pb more readily than adults Fluoride increases Pb absorption Lead burden can cause learning disability

ADD hyperactivity deliquency Synergy with Mercury increases toxicity

exponentially Safe threshold changed from 60ugdl to

10ugdl Children with blood levels of 10 mcgdl the

upper limit of the ldquosafe rangerdquo have IQs 75 points below those of kids whose blood Pb levels are 0-1mcgdl

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Provocative Testing is often unconvincing in ASD due to impaired detoxification

Urine Toxics Fecal Toxics and Hair Analysis show excretion of toxic metals We have no way to determine total body burden

RBC Blood testing is a poor measure of chronic heavy metal burden However blood may show acute exposure

There are no standards for diagnosing chronic toxicity

There are no tests to determine body burden of metals

Lead is a bone seeker and can only be measured in blood 12 hrs after exposure therefore blood Pb is not an adequate indicator of low level chronic toxicity

Mercury has an affinity for fatty tissue and a developing brain and is very rarely seen in blood

Urinary porphyrin testing

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Stimmy behavior Verbal Perseverative Scripting Rewinding Videos

Obsesses on placement of objects

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Physical Presentation Poor eating Clearing the throat Swollen lymph glands Obsessive

thoughtsbehavior Seizures Motor tics Someone else in the

family has strep Verbal stimming

Treatments Biofilm treatment esp if

strep is found in the stool

Antibiotics Zithromax and others

Probiotics and Prebiotics Immune supportive

agents IVIG Enzymes for biofilm Berberine Golden Seal Oregon grape root

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Mitochondria Dysfunction is a common finding in Autism

Mitochondria are the energy power house of our body

Physical Presentation in Autism Headaches

Headbanging Low muscle

tonehypotonia Poor coordination Fatigue with activity Failure to gain weight Intolerance to fasting Seizures GERD

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Developmental regression and mitochondrial dysfunction in a child with autismJ Child Neurol 2006 Feb21(2)170-2 Poling JS

Aspartate aminotransferase was elevated in 38 of patients with autism compared with 15 of controls (P lt0001) The serum creatine kinase level also was abnormally elevated in 22 (47) of 47 patients with autism These data suggest that further metabolic evaluation is indicated in autistic patients and that defects of oxidative phosphorylation might be prevalent

Mitochondrial dysfunction in autism spectrum disorders a population-based studyDev Med Child Neurol 2005 Mar47(3)185-9Oliveira G

Plasma lactate levels were measured in 69 patients and in 14 we found hyperlactacidemia Five of 11 patients studied were classified with definite mitochondrial respiratory chain disorder suggesting that this might be one of the most common disorders associated with autism (5 of 69 72) and warranting further investigation

Relative carnitine deficiency in autismJ Autism Dev Disord

2004 Dec34(6)615-23Filipek PA Values of free and total carnitine (p lt 0001) and pyruvate (p = 0006) were

significantly reduced while ammonia and alanine levels were considerably elevated (p lt 0001) in our autistic subjects The relative carnitine deficiency in these patients accompanied by slight elevations in lactate and significant elevations in alanine and ammonia levels is suggestive of mild mitochondrial dysfunction

Screening from the pediatrician Ammonia plasma

level Lactic Acid (blood) Carnitine level

(blood) Pyruvic Acid

(blood) Urinary

Methylmalonic Acid

Our Practice Organic acid test Metabolic Analysis

Profile These test look

at the Kreb cycle metabolites

The various enzyme assemblies require vitamins B1 B2 B3 (NADH) B5 biotin and alpha-lipoic acid as coenzymes

Magnesium is also required by most of the glycolytic and Krebs cycle enzymes as a mineral co-factor

The electron transport chain especially relies on NADH and CO Q10 to generate the bulk of the cells ATP

Idebenone is a synthetic variant of Co Q10 that may work better than CoQ10 especially in low oxygen conditions to keep ATP production going in the electron transport chain

Acetyl l-carnitine may regenerate aging mitochondria that are suffering from a lifetime of accumulated free radical damage

Potential Krebs Cycle Support Malic Acid Fumaric Acid Succinic Acid Alpha KetoGlutarate (careful)

Traditional medical practice is one size fits all

Titer Levels can be checked to assess for immunity after a vaccination is given

When checking immunity IgG QUANTITATIVE titer needs to be done this gives you a level of immunity with a

number ie Measles IgG quantitative titer

Stomach Problems can present with Food refusals Arching of the back Toe walking Bloated stomach Daily BMs yet stools are large or scanty Laying over objects to put pressure on the

stomach Head Banging Sour Breath Frequent night waking History of colic Excessive chewing or biting of the arm

GI doctors need to be team players Present a detailed account of the observed

behaviors and how you see this relates to his physical well being andor pain When my child has a BM he cries he refuses to

use the toilet When my child eats I see him arch his back and

he burps a lot My child is able to defecate a stool the size of

the Sears (Willis) Tower and I keep a plunger on hand at all times

Because he has a hard time going he is using his finger to empty the stool out himself

Daily bowel movements are a goal Add digestive enzymes with meals Start high potency probiotics (acidophilus

and bifidus) Start treatment for dysbiosis depending

on symptoms and lab findings If persistent symptoms

Eliminate disaccharides from diet for 3-6 months Specific Carbohydrate Diet

Consider referral to knowledgeable GI specialist

Consider trial of IV Secretin Add natural anti-inflammatory agents

Keep close eye on gut during any detox regimen bull35

CaseinGluten Free DietCaseinGluten Free Diet

Persistent Gut IssuesPersistent Gut Issues HyperactivityStimmingHyperactivityStimming

SpecificSpecificCarbohydrateCarbohydrate

DietDiet

Body Ecology Body Ecology DietDiet

Low Oxalate Low Oxalate Diet Diet

Avoid ExcitotoxinsAvoid Excitotoxins

Low PhenolicFeingoldLow PhenolicFeingoldDiet Diet

Low Copper DietLow Copper Diet

EliminationRotationEliminationRotationDietDiet

EliminationRotationEliminationRotationDietDiet

bull36

bullDietary OptionsDietary Options

Stool Test Upper

Endoscopy Lower

Endoscopy Contact

other parents to find MD in your area

Behaviors you might see Picking or scratching

at the rectum Frequent night

waking Smelly stools Refusal to be toilet

trained due to pain with stooling

A picture is worth a thousand words Take a picture of

your childrsquos stool if you find it to be abnormal

Video tape a concerning behavior that shows your childrsquos distress

Keep a chart of the types of stool using the Bristol Stool Chart

Bacteria are a major component of colonic material Hundreds of speciesstrains exist in the intestines Metabolic activity affects the host

Digestion Energy Production Metabolism Modulation of the immune system Destruction of toxins and mutagens Repression of pathogenic microbial growth Preventing allergy Preventing inflammatory bowel disease and inflammation

The Colon has an obligate need for bacterial fermentation products (SCFA short chain fatty acids)

ldquothe species composition and biochemical activities of the microbial flora are determined primarily by diet and are strongly influenced by carbohydrate availabilityrdquo

ldquoComposition and Metabolic Activities of Bacterial Biofilms Colonizing Food Residues in the Human Gutrdquo (Macfarlane Sept 2006)

Maldigestion Decreased activity of digestive enzymes (Horvath1999 Buie 2004) High levels of opioid peptides found in urine of autistics (Reichelt 1997) IgG Food Sensitivities

Malabsorption Fat Soluble Vitamin Deficiencies Essential Fatty Acid Deficiencies Omega 3 Deficiencies Essential Amino Acid Deficiencies

Dysbiosis Dysbiosis or altered bowel flora (Rossenau 2004) Clostridial overgrowth (Sandler 2002 McFabe 2007) Persistent measles virus (Wakefield Krigsman)

Gut Inflammation Autistic Enterocolitis Lymphoid Hyperplasia (Wakefield1998) Increased intestinal permeability leading to food sensitivities and

autoimmunity (Vodjani 2002)

Increased pro-inflammatory cytokines ndash LP TNF alpha IFN gamma (Ashwood 2004 Jyonuchi 2005) Proinflammatory response to dietary proteins (Jyonuchi 2004) Proinflammation similar to Autistics found in immunized Monkeys (Hewitson

2008)

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
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• Slide 53
• Slide 54
• Slide 55
• Slide 56

The various enzyme assemblies require vitamins B1 B2 B3 (NADH) B5 biotin and alpha-lipoic acid as coenzymes

Magnesium is also required by most of the glycolytic and Krebs cycle enzymes as a mineral co-factor

The electron transport chain especially relies on NADH and CO Q10 to generate the bulk of the cells ATP

Idebenone is a synthetic variant of Co Q10 that may work better than CoQ10 especially in low oxygen conditions to keep ATP production going in the electron transport chain

Acetyl l-carnitine may regenerate aging mitochondria that are suffering from a lifetime of accumulated free radical damage

Potential Krebs Cycle Support Malic Acid Fumaric Acid Succinic Acid Alpha KetoGlutarate (careful)

Traditional medical practice is one size fits all

Titer Levels can be checked to assess for immunity after a vaccination is given

When checking immunity IgG QUANTITATIVE titer needs to be done this gives you a level of immunity with a

number ie Measles IgG quantitative titer

Stomach Problems can present with Food refusals Arching of the back Toe walking Bloated stomach Daily BMs yet stools are large or scanty Laying over objects to put pressure on the

stomach Head Banging Sour Breath Frequent night waking History of colic Excessive chewing or biting of the arm

GI doctors need to be team players Present a detailed account of the observed

behaviors and how you see this relates to his physical well being andor pain When my child has a BM he cries he refuses to

use the toilet When my child eats I see him arch his back and

he burps a lot My child is able to defecate a stool the size of

the Sears (Willis) Tower and I keep a plunger on hand at all times

Because he has a hard time going he is using his finger to empty the stool out himself

Daily bowel movements are a goal Add digestive enzymes with meals Start high potency probiotics (acidophilus

and bifidus) Start treatment for dysbiosis depending

on symptoms and lab findings If persistent symptoms

Eliminate disaccharides from diet for 3-6 months Specific Carbohydrate Diet

Consider referral to knowledgeable GI specialist

Consider trial of IV Secretin Add natural anti-inflammatory agents

Keep close eye on gut during any detox regimen bull35

CaseinGluten Free DietCaseinGluten Free Diet

Persistent Gut IssuesPersistent Gut Issues HyperactivityStimmingHyperactivityStimming

SpecificSpecificCarbohydrateCarbohydrate

DietDiet

Body Ecology Body Ecology DietDiet

Low Oxalate Low Oxalate Diet Diet

Avoid ExcitotoxinsAvoid Excitotoxins

Low PhenolicFeingoldLow PhenolicFeingoldDiet Diet

Low Copper DietLow Copper Diet

EliminationRotationEliminationRotationDietDiet

EliminationRotationEliminationRotationDietDiet

bull36

bullDietary OptionsDietary Options

Stool Test Upper

Endoscopy Lower

Endoscopy Contact

other parents to find MD in your area

Behaviors you might see Picking or scratching

at the rectum Frequent night

waking Smelly stools Refusal to be toilet

trained due to pain with stooling

A picture is worth a thousand words Take a picture of

your childrsquos stool if you find it to be abnormal

Video tape a concerning behavior that shows your childrsquos distress

Keep a chart of the types of stool using the Bristol Stool Chart

Bacteria are a major component of colonic material Hundreds of speciesstrains exist in the intestines Metabolic activity affects the host

Digestion Energy Production Metabolism Modulation of the immune system Destruction of toxins and mutagens Repression of pathogenic microbial growth Preventing allergy Preventing inflammatory bowel disease and inflammation

The Colon has an obligate need for bacterial fermentation products (SCFA short chain fatty acids)

ldquothe species composition and biochemical activities of the microbial flora are determined primarily by diet and are strongly influenced by carbohydrate availabilityrdquo

ldquoComposition and Metabolic Activities of Bacterial Biofilms Colonizing Food Residues in the Human Gutrdquo (Macfarlane Sept 2006)

Maldigestion Decreased activity of digestive enzymes (Horvath1999 Buie 2004) High levels of opioid peptides found in urine of autistics (Reichelt 1997) IgG Food Sensitivities

Malabsorption Fat Soluble Vitamin Deficiencies Essential Fatty Acid Deficiencies Omega 3 Deficiencies Essential Amino Acid Deficiencies

Dysbiosis Dysbiosis or altered bowel flora (Rossenau 2004) Clostridial overgrowth (Sandler 2002 McFabe 2007) Persistent measles virus (Wakefield Krigsman)

Gut Inflammation Autistic Enterocolitis Lymphoid Hyperplasia (Wakefield1998) Increased intestinal permeability leading to food sensitivities and

autoimmunity (Vodjani 2002)

Increased pro-inflammatory cytokines ndash LP TNF alpha IFN gamma (Ashwood 2004 Jyonuchi 2005) Proinflammatory response to dietary proteins (Jyonuchi 2004) Proinflammation similar to Autistics found in immunized Monkeys (Hewitson

2008)

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
• Slide 8
• Slide 9
• Slide 10
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• Slide 46
• Slide 47
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• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Traditional medical practice is one size fits all

Titer Levels can be checked to assess for immunity after a vaccination is given

When checking immunity IgG QUANTITATIVE titer needs to be done this gives you a level of immunity with a

number ie Measles IgG quantitative titer

Stomach Problems can present with Food refusals Arching of the back Toe walking Bloated stomach Daily BMs yet stools are large or scanty Laying over objects to put pressure on the

stomach Head Banging Sour Breath Frequent night waking History of colic Excessive chewing or biting of the arm

GI doctors need to be team players Present a detailed account of the observed

behaviors and how you see this relates to his physical well being andor pain When my child has a BM he cries he refuses to

use the toilet When my child eats I see him arch his back and

he burps a lot My child is able to defecate a stool the size of

the Sears (Willis) Tower and I keep a plunger on hand at all times

Because he has a hard time going he is using his finger to empty the stool out himself

Daily bowel movements are a goal Add digestive enzymes with meals Start high potency probiotics (acidophilus

and bifidus) Start treatment for dysbiosis depending

on symptoms and lab findings If persistent symptoms

Eliminate disaccharides from diet for 3-6 months Specific Carbohydrate Diet

Consider referral to knowledgeable GI specialist

Consider trial of IV Secretin Add natural anti-inflammatory agents

Keep close eye on gut during any detox regimen bull35

CaseinGluten Free DietCaseinGluten Free Diet

Persistent Gut IssuesPersistent Gut Issues HyperactivityStimmingHyperactivityStimming

SpecificSpecificCarbohydrateCarbohydrate

DietDiet

Body Ecology Body Ecology DietDiet

Low Oxalate Low Oxalate Diet Diet

Avoid ExcitotoxinsAvoid Excitotoxins

Low PhenolicFeingoldLow PhenolicFeingoldDiet Diet

Low Copper DietLow Copper Diet

EliminationRotationEliminationRotationDietDiet

EliminationRotationEliminationRotationDietDiet

bull36

bullDietary OptionsDietary Options

Stool Test Upper

Endoscopy Lower

Endoscopy Contact

other parents to find MD in your area

Behaviors you might see Picking or scratching

at the rectum Frequent night

waking Smelly stools Refusal to be toilet

trained due to pain with stooling

A picture is worth a thousand words Take a picture of

your childrsquos stool if you find it to be abnormal

Video tape a concerning behavior that shows your childrsquos distress

Keep a chart of the types of stool using the Bristol Stool Chart

Bacteria are a major component of colonic material Hundreds of speciesstrains exist in the intestines Metabolic activity affects the host

Digestion Energy Production Metabolism Modulation of the immune system Destruction of toxins and mutagens Repression of pathogenic microbial growth Preventing allergy Preventing inflammatory bowel disease and inflammation

The Colon has an obligate need for bacterial fermentation products (SCFA short chain fatty acids)

ldquothe species composition and biochemical activities of the microbial flora are determined primarily by diet and are strongly influenced by carbohydrate availabilityrdquo

ldquoComposition and Metabolic Activities of Bacterial Biofilms Colonizing Food Residues in the Human Gutrdquo (Macfarlane Sept 2006)

Maldigestion Decreased activity of digestive enzymes (Horvath1999 Buie 2004) High levels of opioid peptides found in urine of autistics (Reichelt 1997) IgG Food Sensitivities

Malabsorption Fat Soluble Vitamin Deficiencies Essential Fatty Acid Deficiencies Omega 3 Deficiencies Essential Amino Acid Deficiencies

Dysbiosis Dysbiosis or altered bowel flora (Rossenau 2004) Clostridial overgrowth (Sandler 2002 McFabe 2007) Persistent measles virus (Wakefield Krigsman)

Gut Inflammation Autistic Enterocolitis Lymphoid Hyperplasia (Wakefield1998) Increased intestinal permeability leading to food sensitivities and

autoimmunity (Vodjani 2002)

Increased pro-inflammatory cytokines ndash LP TNF alpha IFN gamma (Ashwood 2004 Jyonuchi 2005) Proinflammatory response to dietary proteins (Jyonuchi 2004) Proinflammation similar to Autistics found in immunized Monkeys (Hewitson

2008)

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
• Slide 8
• Slide 9
• Slide 10
• Slide 11
• Slide 12
• Slide 13
• Slide 14
• Slide 15
• Slide 16
• Slide 17
• Slide 18
• Slide 19
• Slide 20
• Slide 21
• Slide 22
• Slide 23
• Slide 24
• Slide 25
• Slide 26
• Slide 27
• Slide 28
• Slide 29
• Slide 30
• Slide 31
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• Slide 33
• Slide 34
• Slide 35
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• Slide 37
• Slide 38
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• Slide 40
• Slide 41
• Slide 42
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• Slide 44
• Slide 45
• Slide 46
• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Stomach Problems can present with Food refusals Arching of the back Toe walking Bloated stomach Daily BMs yet stools are large or scanty Laying over objects to put pressure on the

stomach Head Banging Sour Breath Frequent night waking History of colic Excessive chewing or biting of the arm

GI doctors need to be team players Present a detailed account of the observed

behaviors and how you see this relates to his physical well being andor pain When my child has a BM he cries he refuses to

use the toilet When my child eats I see him arch his back and

he burps a lot My child is able to defecate a stool the size of

the Sears (Willis) Tower and I keep a plunger on hand at all times

Because he has a hard time going he is using his finger to empty the stool out himself

Daily bowel movements are a goal Add digestive enzymes with meals Start high potency probiotics (acidophilus

and bifidus) Start treatment for dysbiosis depending

on symptoms and lab findings If persistent symptoms

Eliminate disaccharides from diet for 3-6 months Specific Carbohydrate Diet

Consider referral to knowledgeable GI specialist

Consider trial of IV Secretin Add natural anti-inflammatory agents

Keep close eye on gut during any detox regimen bull35

CaseinGluten Free DietCaseinGluten Free Diet

Persistent Gut IssuesPersistent Gut Issues HyperactivityStimmingHyperactivityStimming

SpecificSpecificCarbohydrateCarbohydrate

DietDiet

Body Ecology Body Ecology DietDiet

Low Oxalate Low Oxalate Diet Diet

Avoid ExcitotoxinsAvoid Excitotoxins

Low PhenolicFeingoldLow PhenolicFeingoldDiet Diet

Low Copper DietLow Copper Diet

EliminationRotationEliminationRotationDietDiet

EliminationRotationEliminationRotationDietDiet

bull36

bullDietary OptionsDietary Options

Stool Test Upper

Endoscopy Lower

Endoscopy Contact

other parents to find MD in your area

Behaviors you might see Picking or scratching

at the rectum Frequent night

waking Smelly stools Refusal to be toilet

trained due to pain with stooling

A picture is worth a thousand words Take a picture of

your childrsquos stool if you find it to be abnormal

Video tape a concerning behavior that shows your childrsquos distress

Keep a chart of the types of stool using the Bristol Stool Chart

Bacteria are a major component of colonic material Hundreds of speciesstrains exist in the intestines Metabolic activity affects the host

Digestion Energy Production Metabolism Modulation of the immune system Destruction of toxins and mutagens Repression of pathogenic microbial growth Preventing allergy Preventing inflammatory bowel disease and inflammation

The Colon has an obligate need for bacterial fermentation products (SCFA short chain fatty acids)

ldquothe species composition and biochemical activities of the microbial flora are determined primarily by diet and are strongly influenced by carbohydrate availabilityrdquo

ldquoComposition and Metabolic Activities of Bacterial Biofilms Colonizing Food Residues in the Human Gutrdquo (Macfarlane Sept 2006)

Maldigestion Decreased activity of digestive enzymes (Horvath1999 Buie 2004) High levels of opioid peptides found in urine of autistics (Reichelt 1997) IgG Food Sensitivities

Malabsorption Fat Soluble Vitamin Deficiencies Essential Fatty Acid Deficiencies Omega 3 Deficiencies Essential Amino Acid Deficiencies

Dysbiosis Dysbiosis or altered bowel flora (Rossenau 2004) Clostridial overgrowth (Sandler 2002 McFabe 2007) Persistent measles virus (Wakefield Krigsman)

Gut Inflammation Autistic Enterocolitis Lymphoid Hyperplasia (Wakefield1998) Increased intestinal permeability leading to food sensitivities and

autoimmunity (Vodjani 2002)

Increased pro-inflammatory cytokines ndash LP TNF alpha IFN gamma (Ashwood 2004 Jyonuchi 2005) Proinflammatory response to dietary proteins (Jyonuchi 2004) Proinflammation similar to Autistics found in immunized Monkeys (Hewitson

2008)

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
• Slide 8
• Slide 9
• Slide 10
• Slide 11
• Slide 12
• Slide 13
• Slide 14
• Slide 15
• Slide 16
• Slide 17
• Slide 18
• Slide 19
• Slide 20
• Slide 21
• Slide 22
• Slide 23
• Slide 24
• Slide 25
• Slide 26
• Slide 27
• Slide 28
• Slide 29
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• Slide 31
• Slide 32
• Slide 33
• Slide 34
• Slide 35
• Slide 36
• Slide 37
• Slide 38
• Slide 39
• Slide 40
• Slide 41
• Slide 42
• Slide 43
• Slide 44
• Slide 45
• Slide 46
• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

GI doctors need to be team players Present a detailed account of the observed

behaviors and how you see this relates to his physical well being andor pain When my child has a BM he cries he refuses to

use the toilet When my child eats I see him arch his back and

he burps a lot My child is able to defecate a stool the size of

the Sears (Willis) Tower and I keep a plunger on hand at all times

Because he has a hard time going he is using his finger to empty the stool out himself

Daily bowel movements are a goal Add digestive enzymes with meals Start high potency probiotics (acidophilus

and bifidus) Start treatment for dysbiosis depending

on symptoms and lab findings If persistent symptoms

Eliminate disaccharides from diet for 3-6 months Specific Carbohydrate Diet

Consider referral to knowledgeable GI specialist

Consider trial of IV Secretin Add natural anti-inflammatory agents

Keep close eye on gut during any detox regimen bull35

CaseinGluten Free DietCaseinGluten Free Diet

Persistent Gut IssuesPersistent Gut Issues HyperactivityStimmingHyperactivityStimming

SpecificSpecificCarbohydrateCarbohydrate

DietDiet

Body Ecology Body Ecology DietDiet

Low Oxalate Low Oxalate Diet Diet

Avoid ExcitotoxinsAvoid Excitotoxins

Low PhenolicFeingoldLow PhenolicFeingoldDiet Diet

Low Copper DietLow Copper Diet

EliminationRotationEliminationRotationDietDiet

EliminationRotationEliminationRotationDietDiet

bull36

bullDietary OptionsDietary Options

Stool Test Upper

Endoscopy Lower

Endoscopy Contact

other parents to find MD in your area

Behaviors you might see Picking or scratching

at the rectum Frequent night

waking Smelly stools Refusal to be toilet

trained due to pain with stooling

A picture is worth a thousand words Take a picture of

your childrsquos stool if you find it to be abnormal

Video tape a concerning behavior that shows your childrsquos distress

Keep a chart of the types of stool using the Bristol Stool Chart

Bacteria are a major component of colonic material Hundreds of speciesstrains exist in the intestines Metabolic activity affects the host

Digestion Energy Production Metabolism Modulation of the immune system Destruction of toxins and mutagens Repression of pathogenic microbial growth Preventing allergy Preventing inflammatory bowel disease and inflammation

The Colon has an obligate need for bacterial fermentation products (SCFA short chain fatty acids)

ldquothe species composition and biochemical activities of the microbial flora are determined primarily by diet and are strongly influenced by carbohydrate availabilityrdquo

ldquoComposition and Metabolic Activities of Bacterial Biofilms Colonizing Food Residues in the Human Gutrdquo (Macfarlane Sept 2006)

Maldigestion Decreased activity of digestive enzymes (Horvath1999 Buie 2004) High levels of opioid peptides found in urine of autistics (Reichelt 1997) IgG Food Sensitivities

Malabsorption Fat Soluble Vitamin Deficiencies Essential Fatty Acid Deficiencies Omega 3 Deficiencies Essential Amino Acid Deficiencies

Dysbiosis Dysbiosis or altered bowel flora (Rossenau 2004) Clostridial overgrowth (Sandler 2002 McFabe 2007) Persistent measles virus (Wakefield Krigsman)

Gut Inflammation Autistic Enterocolitis Lymphoid Hyperplasia (Wakefield1998) Increased intestinal permeability leading to food sensitivities and

autoimmunity (Vodjani 2002)

Increased pro-inflammatory cytokines ndash LP TNF alpha IFN gamma (Ashwood 2004 Jyonuchi 2005) Proinflammatory response to dietary proteins (Jyonuchi 2004) Proinflammation similar to Autistics found in immunized Monkeys (Hewitson

2008)

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
• Slide 8
• Slide 9
• Slide 10
• Slide 11
• Slide 12
• Slide 13
• Slide 14
• Slide 15
• Slide 16
• Slide 17
• Slide 18
• Slide 19
• Slide 20
• Slide 21
• Slide 22
• Slide 23
• Slide 24
• Slide 25
• Slide 26
• Slide 27
• Slide 28
• Slide 29
• Slide 30
• Slide 31
• Slide 32
• Slide 33
• Slide 34
• Slide 35
• Slide 36
• Slide 37
• Slide 38
• Slide 39
• Slide 40
• Slide 41
• Slide 42
• Slide 43
• Slide 44
• Slide 45
• Slide 46
• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Daily bowel movements are a goal Add digestive enzymes with meals Start high potency probiotics (acidophilus

and bifidus) Start treatment for dysbiosis depending

on symptoms and lab findings If persistent symptoms

Eliminate disaccharides from diet for 3-6 months Specific Carbohydrate Diet

Consider referral to knowledgeable GI specialist

Consider trial of IV Secretin Add natural anti-inflammatory agents

Keep close eye on gut during any detox regimen bull35

CaseinGluten Free DietCaseinGluten Free Diet

Persistent Gut IssuesPersistent Gut Issues HyperactivityStimmingHyperactivityStimming

SpecificSpecificCarbohydrateCarbohydrate

DietDiet

Body Ecology Body Ecology DietDiet

Low Oxalate Low Oxalate Diet Diet

Avoid ExcitotoxinsAvoid Excitotoxins

Low PhenolicFeingoldLow PhenolicFeingoldDiet Diet

Low Copper DietLow Copper Diet

EliminationRotationEliminationRotationDietDiet

EliminationRotationEliminationRotationDietDiet

bull36

bullDietary OptionsDietary Options

Stool Test Upper

Endoscopy Lower

Endoscopy Contact

other parents to find MD in your area

Behaviors you might see Picking or scratching

at the rectum Frequent night

waking Smelly stools Refusal to be toilet

trained due to pain with stooling

A picture is worth a thousand words Take a picture of

your childrsquos stool if you find it to be abnormal

Video tape a concerning behavior that shows your childrsquos distress

Keep a chart of the types of stool using the Bristol Stool Chart

Bacteria are a major component of colonic material Hundreds of speciesstrains exist in the intestines Metabolic activity affects the host

Digestion Energy Production Metabolism Modulation of the immune system Destruction of toxins and mutagens Repression of pathogenic microbial growth Preventing allergy Preventing inflammatory bowel disease and inflammation

The Colon has an obligate need for bacterial fermentation products (SCFA short chain fatty acids)

ldquothe species composition and biochemical activities of the microbial flora are determined primarily by diet and are strongly influenced by carbohydrate availabilityrdquo

ldquoComposition and Metabolic Activities of Bacterial Biofilms Colonizing Food Residues in the Human Gutrdquo (Macfarlane Sept 2006)

Maldigestion Decreased activity of digestive enzymes (Horvath1999 Buie 2004) High levels of opioid peptides found in urine of autistics (Reichelt 1997) IgG Food Sensitivities

Malabsorption Fat Soluble Vitamin Deficiencies Essential Fatty Acid Deficiencies Omega 3 Deficiencies Essential Amino Acid Deficiencies

Dysbiosis Dysbiosis or altered bowel flora (Rossenau 2004) Clostridial overgrowth (Sandler 2002 McFabe 2007) Persistent measles virus (Wakefield Krigsman)

Gut Inflammation Autistic Enterocolitis Lymphoid Hyperplasia (Wakefield1998) Increased intestinal permeability leading to food sensitivities and

autoimmunity (Vodjani 2002)

Increased pro-inflammatory cytokines ndash LP TNF alpha IFN gamma (Ashwood 2004 Jyonuchi 2005) Proinflammatory response to dietary proteins (Jyonuchi 2004) Proinflammation similar to Autistics found in immunized Monkeys (Hewitson

2008)

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
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• Slide 3
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CaseinGluten Free DietCaseinGluten Free Diet

Persistent Gut IssuesPersistent Gut Issues HyperactivityStimmingHyperactivityStimming

SpecificSpecificCarbohydrateCarbohydrate

DietDiet

Body Ecology Body Ecology DietDiet

Low Oxalate Low Oxalate Diet Diet

Avoid ExcitotoxinsAvoid Excitotoxins

Low PhenolicFeingoldLow PhenolicFeingoldDiet Diet

Low Copper DietLow Copper Diet

EliminationRotationEliminationRotationDietDiet

EliminationRotationEliminationRotationDietDiet

bull36

bullDietary OptionsDietary Options

Stool Test Upper

Endoscopy Lower

Endoscopy Contact

other parents to find MD in your area

Behaviors you might see Picking or scratching

at the rectum Frequent night

waking Smelly stools Refusal to be toilet

trained due to pain with stooling

A picture is worth a thousand words Take a picture of

your childrsquos stool if you find it to be abnormal

Video tape a concerning behavior that shows your childrsquos distress

Keep a chart of the types of stool using the Bristol Stool Chart

Bacteria are a major component of colonic material Hundreds of speciesstrains exist in the intestines Metabolic activity affects the host

Digestion Energy Production Metabolism Modulation of the immune system Destruction of toxins and mutagens Repression of pathogenic microbial growth Preventing allergy Preventing inflammatory bowel disease and inflammation

The Colon has an obligate need for bacterial fermentation products (SCFA short chain fatty acids)

ldquothe species composition and biochemical activities of the microbial flora are determined primarily by diet and are strongly influenced by carbohydrate availabilityrdquo

ldquoComposition and Metabolic Activities of Bacterial Biofilms Colonizing Food Residues in the Human Gutrdquo (Macfarlane Sept 2006)

Maldigestion Decreased activity of digestive enzymes (Horvath1999 Buie 2004) High levels of opioid peptides found in urine of autistics (Reichelt 1997) IgG Food Sensitivities

Malabsorption Fat Soluble Vitamin Deficiencies Essential Fatty Acid Deficiencies Omega 3 Deficiencies Essential Amino Acid Deficiencies

Dysbiosis Dysbiosis or altered bowel flora (Rossenau 2004) Clostridial overgrowth (Sandler 2002 McFabe 2007) Persistent measles virus (Wakefield Krigsman)

Gut Inflammation Autistic Enterocolitis Lymphoid Hyperplasia (Wakefield1998) Increased intestinal permeability leading to food sensitivities and

autoimmunity (Vodjani 2002)

Increased pro-inflammatory cytokines ndash LP TNF alpha IFN gamma (Ashwood 2004 Jyonuchi 2005) Proinflammatory response to dietary proteins (Jyonuchi 2004) Proinflammation similar to Autistics found in immunized Monkeys (Hewitson

2008)

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
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• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Stool Test Upper

Endoscopy Lower

Endoscopy Contact

other parents to find MD in your area

Behaviors you might see Picking or scratching

at the rectum Frequent night

waking Smelly stools Refusal to be toilet

trained due to pain with stooling

A picture is worth a thousand words Take a picture of

your childrsquos stool if you find it to be abnormal

Video tape a concerning behavior that shows your childrsquos distress

Keep a chart of the types of stool using the Bristol Stool Chart

Bacteria are a major component of colonic material Hundreds of speciesstrains exist in the intestines Metabolic activity affects the host

Digestion Energy Production Metabolism Modulation of the immune system Destruction of toxins and mutagens Repression of pathogenic microbial growth Preventing allergy Preventing inflammatory bowel disease and inflammation

The Colon has an obligate need for bacterial fermentation products (SCFA short chain fatty acids)

ldquothe species composition and biochemical activities of the microbial flora are determined primarily by diet and are strongly influenced by carbohydrate availabilityrdquo

ldquoComposition and Metabolic Activities of Bacterial Biofilms Colonizing Food Residues in the Human Gutrdquo (Macfarlane Sept 2006)

Maldigestion Decreased activity of digestive enzymes (Horvath1999 Buie 2004) High levels of opioid peptides found in urine of autistics (Reichelt 1997) IgG Food Sensitivities

Malabsorption Fat Soluble Vitamin Deficiencies Essential Fatty Acid Deficiencies Omega 3 Deficiencies Essential Amino Acid Deficiencies

Dysbiosis Dysbiosis or altered bowel flora (Rossenau 2004) Clostridial overgrowth (Sandler 2002 McFabe 2007) Persistent measles virus (Wakefield Krigsman)

Gut Inflammation Autistic Enterocolitis Lymphoid Hyperplasia (Wakefield1998) Increased intestinal permeability leading to food sensitivities and

autoimmunity (Vodjani 2002)

Increased pro-inflammatory cytokines ndash LP TNF alpha IFN gamma (Ashwood 2004 Jyonuchi 2005) Proinflammatory response to dietary proteins (Jyonuchi 2004) Proinflammation similar to Autistics found in immunized Monkeys (Hewitson

2008)

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
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• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

A picture is worth a thousand words Take a picture of

your childrsquos stool if you find it to be abnormal

Video tape a concerning behavior that shows your childrsquos distress

Keep a chart of the types of stool using the Bristol Stool Chart

Bacteria are a major component of colonic material Hundreds of speciesstrains exist in the intestines Metabolic activity affects the host

Digestion Energy Production Metabolism Modulation of the immune system Destruction of toxins and mutagens Repression of pathogenic microbial growth Preventing allergy Preventing inflammatory bowel disease and inflammation

The Colon has an obligate need for bacterial fermentation products (SCFA short chain fatty acids)

ldquothe species composition and biochemical activities of the microbial flora are determined primarily by diet and are strongly influenced by carbohydrate availabilityrdquo

ldquoComposition and Metabolic Activities of Bacterial Biofilms Colonizing Food Residues in the Human Gutrdquo (Macfarlane Sept 2006)

Maldigestion Decreased activity of digestive enzymes (Horvath1999 Buie 2004) High levels of opioid peptides found in urine of autistics (Reichelt 1997) IgG Food Sensitivities

Malabsorption Fat Soluble Vitamin Deficiencies Essential Fatty Acid Deficiencies Omega 3 Deficiencies Essential Amino Acid Deficiencies

Dysbiosis Dysbiosis or altered bowel flora (Rossenau 2004) Clostridial overgrowth (Sandler 2002 McFabe 2007) Persistent measles virus (Wakefield Krigsman)

Gut Inflammation Autistic Enterocolitis Lymphoid Hyperplasia (Wakefield1998) Increased intestinal permeability leading to food sensitivities and

autoimmunity (Vodjani 2002)

Increased pro-inflammatory cytokines ndash LP TNF alpha IFN gamma (Ashwood 2004 Jyonuchi 2005) Proinflammatory response to dietary proteins (Jyonuchi 2004) Proinflammation similar to Autistics found in immunized Monkeys (Hewitson

2008)

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
• Slide 8
• Slide 9
• Slide 10
• Slide 11
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• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Bacteria are a major component of colonic material Hundreds of speciesstrains exist in the intestines Metabolic activity affects the host

Digestion Energy Production Metabolism Modulation of the immune system Destruction of toxins and mutagens Repression of pathogenic microbial growth Preventing allergy Preventing inflammatory bowel disease and inflammation

The Colon has an obligate need for bacterial fermentation products (SCFA short chain fatty acids)

ldquothe species composition and biochemical activities of the microbial flora are determined primarily by diet and are strongly influenced by carbohydrate availabilityrdquo

ldquoComposition and Metabolic Activities of Bacterial Biofilms Colonizing Food Residues in the Human Gutrdquo (Macfarlane Sept 2006)

Maldigestion Decreased activity of digestive enzymes (Horvath1999 Buie 2004) High levels of opioid peptides found in urine of autistics (Reichelt 1997) IgG Food Sensitivities

Malabsorption Fat Soluble Vitamin Deficiencies Essential Fatty Acid Deficiencies Omega 3 Deficiencies Essential Amino Acid Deficiencies

Dysbiosis Dysbiosis or altered bowel flora (Rossenau 2004) Clostridial overgrowth (Sandler 2002 McFabe 2007) Persistent measles virus (Wakefield Krigsman)

Gut Inflammation Autistic Enterocolitis Lymphoid Hyperplasia (Wakefield1998) Increased intestinal permeability leading to food sensitivities and

autoimmunity (Vodjani 2002)

Increased pro-inflammatory cytokines ndash LP TNF alpha IFN gamma (Ashwood 2004 Jyonuchi 2005) Proinflammatory response to dietary proteins (Jyonuchi 2004) Proinflammation similar to Autistics found in immunized Monkeys (Hewitson

2008)

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
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Maldigestion Decreased activity of digestive enzymes (Horvath1999 Buie 2004) High levels of opioid peptides found in urine of autistics (Reichelt 1997) IgG Food Sensitivities

Malabsorption Fat Soluble Vitamin Deficiencies Essential Fatty Acid Deficiencies Omega 3 Deficiencies Essential Amino Acid Deficiencies

Dysbiosis Dysbiosis or altered bowel flora (Rossenau 2004) Clostridial overgrowth (Sandler 2002 McFabe 2007) Persistent measles virus (Wakefield Krigsman)

Gut Inflammation Autistic Enterocolitis Lymphoid Hyperplasia (Wakefield1998) Increased intestinal permeability leading to food sensitivities and

autoimmunity (Vodjani 2002)

Increased pro-inflammatory cytokines ndash LP TNF alpha IFN gamma (Ashwood 2004 Jyonuchi 2005) Proinflammatory response to dietary proteins (Jyonuchi 2004) Proinflammation similar to Autistics found in immunized Monkeys (Hewitson

2008)

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
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• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Stool testing CDSA CPP x3 Microbiology

Urine organic acid test (OAT) Great Plains lab- OAT Metabolic Analysis Profile (MAP) Genova

diagnostics

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
• Slide 8
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• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Giggly inappropriate laughing Foggy spacey Change in bowel movements (foulyeasty

smelling stools) gas and bloated belly Yeasty rashdiaper rash white coating on

tongue red ring around the anus ringworm cradle cap

Bedwetting or accidents Sleep disturbance or Night waking Hyperactivity hand flapping toe walking Sugar craving

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
• Slide 8
• Slide 9
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• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Antifungals Drugs

Nystatin Ampho B Fluconazole Itraconazole Ketoconazole

Herbals Berberine Grapefruit Seed Extract Oil of Oregano Pau drsquoArco Garlic Samento

Homeopathy

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
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• Slide 49
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• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

What may keep you and your child up at night

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
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• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Discomfort and bloating of stomach Itchy buttocks night waking fecal smearing Diarrhea and constipation Teeth grinding Mal absorption of nutrients pica insatiable

appetite Allergies Behavior changes andor aggression worse at

full moon Picking Biting Restlessness

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
• Slide 8
• Slide 9
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• Slide 45
• Slide 46
• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Probiotics Herbs

Wormwood Black walnut Pumpkin seeds Clove Coconut oil

Homeopathy Antiparasitic medications

Metronidazole Paromomycin

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
• Slide 6
• Slide 7
• Slide 8
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• Slide 54
• Slide 55
• Slide 56

They donrsquot go down without a fight

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
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• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Symptoms Irritability aggression behavioral issues Increased stimming hyperactivity sleeplessness Skin rash diaper rash fever

Possible Causes Side effect of supplement or allergy to drug Yeast or Bacterial Flare-up (Balancing act) Detox Reaction = Too rapid of an effect leading to

vitamin or mineral deficiency oxidative stress liver or kidney stress

Die off = Rapid death of gut bugs leading to excess release of toxins and subsequent liver or kidney stress

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
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• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Rate severity if severe stop supplement notify physician

Treat with Activated charcoalBentonite clay andor Alka Seltzer Gold homeopathic remedy if helpful probably die off

Rule out dysbiosis treat accordingly Check ammonia level Add Liver Support

Milk thistle artichoke extract dandelion root Give at bedtime

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
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• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

IMPORTANT to continue to monitor symptoms

Labs can only help point us in the right direction

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
• Slide 4
• Slide 5
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• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Find the puzzle pieces

Identify the color and shape of your puzzle piece

Assemble professionals that can help build your puzzle

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
• Slide 2
• Slide 3
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• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

httpwwwautismcom - Autism Research Institute

Pub Medline is an online medical journal web site httpwwwncbinlmnihgovsitesentrez

Book Dorlandrsquos Illustrated Medical Dictionary

Book Prescription for Nutritional Health and Healing by Balch and Balch

Keep all your reports in a binder Join parent support groups in your area Join yahoo groups Attend conferences

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
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• Slide 47
• Slide 48
• Slide 49
• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

Autism Effective Biomedical Treatments Pangborn and Baker

ldquoAutism A Novel Form of Mercury Poisoningrdquo Bernard et al 2000 (wwwsafemindsorg and autismorg)

Changing the Face of Autism Bryan Jepson MD Jane Johnson

Healing the New Childhood Epidemics Ken Bock MD

Children with Starving Brains Jaquelyn McCandless MD

Special Diets for Special Kids Lisa Lewis Evidence of Harm David Kirby

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
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• Slide 50
• Slide 51
• Slide 52
• Slide 53
• Slide 54
• Slide 55
• Slide 56

More research into biomedical interventions Safer vaccines ( to ldquogreen our vaccinesrdquo ) Access for patients to obtain treatment options Insurances companies to recognize that autism

is a medical not psychiatric condition More doctors to become educated To develop new standard of care strategies

David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
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David London Alex Charles Michael Terry Michael Ty Tyler JosephMichael Ethan Nathaniel Dylan RachelAravind Meddha Jeremy Mason AugustAlec Brian Sebastian Eric CameronHendrew Alexis Spencer Ethan TomRyan Zach Alex Henry MichaelJack Nicholas Zach Rachel KirbyAxel Michael Bailey Anna MaxJohn Kaden Zane Luke IanZach Alex Matthew Alex EveJoey Aidan Richard Trevor EricNicholas Murad Alex Joseph AndrewParker Hanna Ben Daniel Clay

• Slide 1
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