Vol. 1, No. 7 June 2020 naturalproductsinsider.com US$20.75

Product Development Guide

PAID CONTENT

Solutions for stress and

cognitive healthNutritional strategies for

cognitive health and stress management formulations

2 Immune health trends and solutions May 2020

Solutions for stress and cognitive healthNutritional strategies for cognitive health and stress management formulations

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4 Immune health trends and solutions May 2020

Solutions for stress and cognitive health

Americans were already among the most stressed-out people in the world, according to Gallup polls—then a global pandemic hit.

Now that millions have lost their livelihoods, families and friends have been separated and so many aspects of life remain in �ux because of the COVID-19 crisis, our stress levels have shot up even more. �e most recent Gallup poll, conducted in late March and early April, found that 60% of U.S. adults experienced signi�cant stress the day before they were surveyed, a whopping 14% increase from January 2018.

As consumers aim to tackle their anxiety, they are increasingly turning to dietary supplements. Nutrition Business Journal predicts that stress and mood support products, already a booming category pre-pandemic, will grow 14.6% in 2020 to capture $967 million in sales.

But this isn’t the only brain-related supplement sector that’ll get a boost from the pandemic and prolonged economic slump expected to follow. �e Great Recession of 2008 proved that dietary supplements are recession resilient, but perhaps more importantly, COVID-19 has prompted consumers to focus more closely on their overall well-being. Knowing that healthy lifestyle habits are instrumental in bolstering their brain, heart, gut and immune system—and that these seemingly disparate aspects of health are actually interconnected—shoppers are seeking out all kinds of condition-speci�c supplements. So, along with stress and mood support, they’re also purchasing products that promote cognitive function, focus and memory.

Further spiking demand for cognitive health supplements, more Americans than ever are working from home because of the pandemic, in front of computer screens, o�en while overseeing child care, elder care or homeschooling. Locking into work mentally and juggling multiple tasks requires focus, stamina, working memory and rapid visual information processing, all of which can be aided by targeted natural products.

Solutions for stress and cognitive healthNutritional strategies for cognitive health and stress management formulations

Knowing that healthy lifestyle habits are instrumental in bolstering their brain, heart, gut and immune system—and that these seemingly disparate aspects of health are actually interconnected—shoppers are seeking out all kinds of condition-specific supplements.

5 Immune health trends and solutions May 2020

Similarly, with �tness centers closed or limiting capacity, sports leagues suspended and races postponed, more consumers are now exercising at home, whether li�ing weights, Zooming boot camps or riding stationary bikes in the basement. �is shi�, too, necessitates greater mental focus and energy and may heighten demand for cognitive support via supplementation, especially in the form of sports nutrition products formulated with nootropic ingredients.

Additionally, the popularity of gaming and eSports has skyrocketed in recent years, opening up a captive new audience for brain health supplements that skews younger than the category’s traditional demographic. Pandemic-spawned stay-at-home orders and widespread cancelations of events and activities have only increased the number of consumers who are gaming and the time they spend doing it. On March 17, Verizon reported a 75% uptick in gaming during peak hours compared to the week prior.

Finally, pandemic and recession aside, the U.S. population is aging rapidly, with the number of people age 65 and older set to climb from 55 million in 2019 to 88 million in 2050, according to the Alzheimer’s Association. Correspondingly, dementia and speci�cally Alzheimer’s disease will become even more prevalent in the coming years. Fearful of losing their cognitive abilities one day, consumers are increasingly taking brain health supplements as a proactive measure to help their brains function at their best and protect against age-related cognitive decline.

Solutions for stress and cognition When searching for supplements to assist in stress

management and cognitive functioning, consumers don’t want to waste their time or money on ine�ective products. �ey desire clean-label formulations made with ingredients that have been sourced responsibly and proven safe and e�cacious by legitimate scienti�c research. Some prefer old standbys such as St. John’s wort, magnesium or SAMe for calm and omega-3s or ginkgo biloba for brain health. Others are on the hunt for more innovative solutions, such as brain-supporting botanical blends and branded nootropic ingredients.

To design cognitive and mental health products that meet consumers’ speci�c needs and demands, dietary supplement formulators and brand holders should investigate the broad spectrum of science-backed natural ingredients available

Solutions for stress and cognitive health

6 Immune health trends and solutions May 2020

Solutions for stress and cognitive health

today. Many are botanical in nature, with long histories of use in Ayurvedic, traditional Chinese or other ancient medicines. �ese include balance-promoting adaptogenic herbs such as bacopa and eleuthero, as well as other botanicals with proven positive e�ects on cognition, clarity, memory or focus. Other herbal extracts engender calm either directly or indirectly by aiding sleep, which in turn eases stress.

Aside from plant-derived ingredients, there is a wealth of high-quality branded solutions that deliver key nutrients and other compounds to boost cognitive functions or help manage stress. Although the body makes certain compounds such as phosphatidylserine or gamma-amino butyric acid on its own, supplementing with these ingredients can assist in speci�c cellular processes instrumental for various brain functions. And while other brain-essential ingredients—magnesium, for example—could be attained through diet, consumers o�en don’t get enough of them from food; thus, bolstering blood levels via supplements can be highly bene�cial.

Whether creating a supplement that boosts brainpower, sharpens focus, prolongs mental stamina, alleviates anxiety or brings balance and calm to the entire body, formulators and brand holders have a solid arsenal of options that can yield safe, e�ective and di�erentiated products.

PAID CONTENT

1 What speci�c ingredients do you offer that support cognitive health, and if applicable, speci�cally

stress management?

MoodEliteTM is our scienti�cally backed, plant-based branded ingredient that is speci�cally formulated with cognitive health in mind by utilizing three TCM herbal extracts: St. John’s Wort (Hypericum perforatum), Eleuthero (Eleutherococcus senticosus) and Mu-Dan-Pi (Paeonia su�ruticosa).

Hypericin, the active ingredient in St. John’s Wort, has been previously found to boost cognitive health by balancing mood in cases of mild depression and occasional anxiety. Eleuthero has also been used to enhance mental function in addition to increasing energy and longevity, all while promoting relaxation and enhancing sleep quality. Lastly, Mu-Dan-Pi has been found to promote blood circulation in addition to other pharmacological e�ects, such as anti-in�ammatory and immunomodulatory properties.

Utilizing these ingredients, MoodEliteTM can e�ectively alleviate occasional anxiety and mild depression, support cognitive health, reduce stress, and promote sleep and relaxation to lighten up your day.

2 What advancements and innovations do you offer?

At Chenland Nutritionals, our R&D team consists of more than 50 members featuring experts from Cornell University, the University of Chicago and other advanced research institutions specializing in product development and formulation. We specialize in TCM-based branded ingredients scienti�cally backed through in vitro and in vivo testing, alongside rigorous preclinical and clinical trials. 

3 Can you provide speci�c studies that support label claims?

Chenland Nutritionals’ R&D team has previously observed parallel studies utilizing the three herbal, TCM ingredients in MoodEliteTM to provide scienti�c validity in enhancing cognitive health. In one study, taking MoodEliteTM increased cognitive activities by increasing positive mental decisions in subjects with mild depression.1 Further studies found that MoodElite could also increase excitability and provide occasional anxiety relief.2 Additionally, MoodEliteTM was found to reduce sleep latency and increase sleep duration by up to 1.4X.3

We are also in the process of conducting human clinical trials with a CRO to further study the e�ect of MoodEliteTM on cognitive health.

4 Do you have a supply chain story, and do you offer speci�c certi�cations (USDA Organic,

non-GMO, etc.)?

MoodEliteTM is manufactured in our own plant with strict quality control. It is in stock currently in our Los Angeles warehouse, and readily available to supply. It is clean label, non-GMO, GMP-certi�ed, gluten free and eco-friendly.

Formulator’s Resource

Q&ACompany Name: Chenland Nutritionals, Inc. Contact Name: Gale AcabalTitle: Product Manager

References: 1) 2 Butterweck V, Hegger M, Winterho� H. Flavonoids of St. John’s Wort reduce HPA axis function in the rat[J]. Planta medica, 2004, 70(10): 1008-1011.2) Gaster B, Holroyd J. St John's wort for depression: a systematic review[J]. Archives of Internal Medicine, 2000, 160(2): 152-156.3) Li W X, Zhou Y P, Lin L, et al. E�ect of extract of Acanthopanax senticosus saponins on sleep performance of mice[J].China Food Addit, 2010, 11: 75-7.

�RELAX

STRESS FREE

Effective Plant-Based

Herbal Formulation

www.chenland.com

Balance Mental Stress

Alleviates Nervousness

Enhances Sleep Quality

Promotes Relaxation and Calmness

LIGHT UP YOUR DAY

MoodElite™ is a specially formulated botanical blend with three traditional Chinese herbs: Hypericum perforatum,Eleutherococcus senticosus, and Paeonia

suffruticosa. Its development was based on 2,000 years Traditional Chinese Medicine history. We make sure to hand-select our ingredients from our Authentic

Medicinal Cultivation Areas with full traceability from harvest to Extract.