Smart Solutionsfor Clinical Trials

We are experts inbespoke AI solutions

Automating AnalysisEF, GLS, LV Volumes

MachineLearning

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ultromics.comcatalyst@ultromics.com© 2020 Ultromics Limited.

Zero Variability Machine learning tools reduce user error and provide accurate results

Reduced Trial TimePProvides highly

reproducible analysis across all vendor

machines, widening patient pool for recruitment, as well as reducing trial size

Full AutomationInterrogates and

enhances retrospective datasets to improve statistical analysis

AI Ready PipelineAbility to build

classifier for disease specific algorithms with retrospective datasets tailored to your study

We are experts inbespoke AI solutions

Automating AnalysisEF, GLS, LV Volumes

Reducing the time and cost of the R&D process, and of clinical trials in particular, is of paramount importance. Our bespoke solution, Catalyst, can leverage machine learning to automate the assessment of echocardiogram images, eliminating variabilities between operators, centralizing analysis for any mumulti-center clinical trial, and allowing a single analysis program to be used on all ultrasound machines.

We use machine learning algorithms which are trained from past clinical examples, through extracting thousands of hidden and complex imaging features not noticeable in traditional visual inspection. As a result, Catalyst can provide highly accurate calculations to power the statistical outcomes of the trial.

OuOur technology is the only so ware that can process both stress and resting echo with or without contrast, providing the flexibility to any retrospective data analysis and widening the patient recruitment pool. We have developed multiple neural networks that can be leveraged to meet each trials unique needs.

Automating Prognosis Reports

Performance Testing and Validation

Case Study Example:

Automating EF, GLS, LV Volumes

Catalyst has been validated and developed through our partnership in the EVAREST trial with the NHS in the UK, one of the largest ultrasound programmes in the world. The EVAREST validation trial continues to run in over 30 NHS hospitals and has recruited over 6000 patients to date

Quality checks are performed on all data being sent and returned to site, including image quality and

protocols

Uncover insights on performance and data, with reports delivered to your inbox every month

24/7 customer support line and dedicated account manager

Streamlined workflow

Quality assurance

Intelligent analytics

24/7 support

The Catalyst Service

Accuracy and precision was assessed against EF, GLS and LV volumes produced by other commercially available software that required manual contouring. Images

were processed by five trained professionally accredited operators*

ItIt was shown to provide accurate and robust measurements of EF, GLS and LV volumes. Inter-operator* variability

demonstrated zero variability when using automated program

*BSE accredited echocardiographers and board certified physicians

The Catalyst program is delivered through the cloud to any existing infrastructure to create a streamlined pathway to accelerate clinical trials. Echocardiogram images are automatically sent to Ultromics for analysis and artificial intelligence assists in automating analysis, sending a report back within minutes

Smart and secure system protects data and users, through

class-leading security standards

Analysis is automated

through the cloud infrastructure within minutes

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ultromics.comcatalyst@ultromics.com© 2020 Ultromics Limited.

Secure-by-design infrastructure re