smallpox vaccine adverse events public health guidance for clinicians a teaching set reviewing key...
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Smallpox Vaccine Adverse EventsPublic Health Guidance for Clinicians
A Teaching Set Reviewing Key Points in the MMWR Report
Expected Vaccination Site Reaction
Normal ReactionDay 7
Normal ReactionDay 12
Major ReactionFirst time vaccinee, Day 6
Major ReactionFirst time vaccinee, Day 10
Major ReactionFirst time vaccinee, Day 15
Major ReactionRevaccinee, Day 4
Major ReactionRevaccinee, Day 8
Major ReactionRevaccinee, Day 10
Major ReactionRevaccinee, Day 15
Fatigue Headache Myalgia Lymphadenopathy Lymphangitis Pruritis Edema at the vaccination site Satellite Lesions
Expected Range of Vaccine Reactions
Rates of Expected Reactions
21% complications required physician consult Most Common Symptoms
Fatigue (50%) Headache (40%) Muscle aches and Chills (20%) Nausea (20%) Fever 37.7 ºC or 100 ºF (10%)
Satellite LesionsNaïve Patient, Day 7
Satellite Lesions
Large Vaccination Reactions and Robust TakesRobust take with lymphangitis
Large Vaccination Reactions and Robust TakesRobust take with lymphangitis
Large Vaccination Reactions and Robust TakesLarge Local Reaction