sickle cell anemia: understanding the molecular biology (peptide.ncsa.uiuc/tutorials)

University of Illinois at Urbana- Champaign Sickle Cell Anemia: Understanding the Molecular Biology (http://peptide.ncsa.uiuc.edu/tutorials) • Sickle Cell Anemia (SCA) is an inherited blood disorder. It affects about 72,000 Americans (see the National Center for Biotechnology Information website for detail facts). • The SCA tutorial, developed in collaboration with teachers, looks at the mutation in hemoglobin that causes this disease. The tutorial utilizes the Biology Workbench as well as the Protein Explorer ( http://www.proteinexplorer.org ), a tool to make visual exploration of protein structure more accessible to students and teachers. The purpose of the tutorial is two- fold: – Provide students with opportunities to learn how to search databases for DNA and protein sequences and then how to align and manipulate these sequences. – Gain a deeper understanding about the molecular biology of SCA, an extremely common and painful disease.

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Sickle Cell Anemia: Understanding the Molecular Biology (http://peptide.ncsa.uiuc.edu/tutorials). Sickle Cell Anemia (SCA) is an inherited blood disorder. It affects about 72,000 Americans (see the National Center for Biotechnology Information website for detail facts). - PowerPoint PPT Presentation

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Page 1: Sickle Cell Anemia: Understanding the Molecular Biology (peptide.ncsa.uiuc/tutorials)

University of Illinois at Urbana-Champaign

Sickle Cell Anemia: Understanding the Molecular Biology(http://peptide.ncsa.uiuc.edu/tutorials)

• Sickle Cell Anemia (SCA) is an inherited blood disorder. It affects about 72,000 Americans (see the National Center for Biotechnology Information website for detail facts).

• The SCA tutorial, developed in collaboration with teachers, looks at the mutation in hemoglobin that causes this disease. The tutorial utilizes the Biology Workbench as well as the Protein Explorer (http://www.proteinexplorer.org), a tool to make visual exploration of protein structure more accessible to students and teachers. The purpose of the tutorial is two-fold:– Provide students with opportunities to learn how to search

databases for DNA and protein sequences and then how to align and manipulate these sequences.

– Gain a deeper understanding about the molecular biology of SCA, an extremely common and painful disease.