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  • 7/27/2019 Shigellosis Treatment

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    10/15/13 Shigellosis Treatment & Management

    emedicine.medscape.com/article/182767-treatment 1/3

    Shigellosis Treatment & Management

    Author: Joyann A Kroser, MD, FACP, FACG, AGAF; Chief Editor: Julian Katz, MD more...

    Updated: May 23, 2013

    Medical Care

    General supportive care of patients with shigellosis includes the following:[6]

    High fever in children should be treated.

    Narcotic-related antidiarrheals should be avoided.

    Antibiotic treatment is indicated in most patients.[7]

    Antimotility agents should be avoided. They have the potential to worsen symptoms and may predispose to

    toxic dilation of the colon.

    For fluid and electrolyte supplementation, oral rehydration solutions are preferable.

    Consultations

    Consult a gastroenterologist or an infectious diseases expert if the Shigella infection is prolonged or if the patient

    experiences a severe course of shigellosis that is unresponsive to antibiotics.

    [8]

    Diet

    Clear liquids followed by a low residue, lactose-free diet are recommended until symptoms of shigellosis resolve.

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    Contributor Information and DisclosuresAuthor

    Joyann A Kroser, MD, FACP, FACG, AGAF Adjunct Clinical Associate Professor of Medicine,

    Gastroenterology, and Hepatology, Drexel University College of Medicine

    Joyann A Kroser, MD, FACP, FACG, AGAF is a member of the following medical societies:Alpha OmegaAlpha,American College of Gastroenterology,American College of Physicians,American Gastroenterological

    Association,American Medical Association,American Society for Gastrointestinal Endoscopy, Crohns and

    Colitis Foundation of America, Pennsylvania Medical Society, Phi Beta Kappa, and Philadelphia County

    Medical Society

    Disclosure: Nothing to disclose.

    Specialty Editor Board

    Ronnie Fass, MD, FACP, FACG Chief of Gastroenterology, Head of Neuroenteric Clinical Research Group,

    Southern Arizona Veterans Affairs Health Care System; Professor of Medicine, Division of Gastroenterology,

    University of Arizona School of Medicine

    Ronnie Fass, MD, FACP, FACG is a member of the following medical societies:American College of

    Gastroenterology ,American College of Physicians-American Society of Internal Medicine,American

    Gastroenterological Association,American Motility Society ,American Society for Gastrointest inal Endoscopy,

    and Israel Medical Association

    http://www.ccfa.org/http://www.gastro.org/http://www.ima.org.il/imaj/http://www.gastro.org/https://profreg.medscape.com/px/registration.dohttps://login.medscape.com/login/sso/getlogin?ac=401http://reference.medscape.com/http://www.medscape.com/http://www.ima.org.il/imaj/http://www.asge.org/http://www.motilitysociety.org/http://www.gastro.org/http://www.acponline.org/http://www.acg.gi.org/http://www.philamedsoc.org/http://www.pbk.org/http://www.pamedsoc.org/http://www.ccfa.org/http://www.asge.org/http://www.ama-assn.org/http://www.gastro.org/http://www.acponline.org/http://www.acg.gi.org/http://www.alphaomegaalpha.org/https://profreg.medscape.com/px/registration.dohttps://login.medscape.com/login/sso/getlogin?ac=401http://www.medscape.org/http://reference.medscape.com/http://www.medscape.com/multispecialtyhttp://www.medscape.com/
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    Disclosure: Takeda Pharmaceuticals Grant/research funds Conducting research; Takeda Pharmaceuticals

    Consulting fee Consulting; Takeda Pharmaceuticals Honoraria Speaking and teaching; Vecta Consulting fee

    Consulting; XenoPort Consulting fee Consulting; Eisai Honoraria Speaking and teaching; Wyeth

    Pharmaceuticals Conducting research; AstraZeneca Grant/research funds Conducting research; Eisai

    Consulting fee Consulting

    Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center

    College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

    Disclosure: Medscape Salary Employment

    Aaron Glatt, MD Chief Administrative Officer, Executive Vice President, Mercy Medical Center, Catholic

    Health Services of Long Island

    Aaron Glatt, MD is a member of the following medical societies:American College of Chest Physicians,

    American College of Physician Executives,American College of Physicians,American College of Physicians-

    American Society of Internal Medicine,American Medical Association,American Society for Microbiology,

    American Thoracic Society, American Venereal Disease Association, Infectious Diseases Society of America,

    International AIDS Society, and Society for Healthcare Epidemiology of America

    Disclosure: Nothing to disclose.

    Alex J Mechaber, MD, FACP Senior Associate Dean for Undergraduate Medical Education, Associate

    Professor of Medicine, University of Miami Miller School of Medicine

    Alex J Mechaber, MD, FACP is a member of the following medical societies: Alpha Omega Alpha,American

    College of Physicians-American Society of Internal Medicine, and Society of General Internal Medicine

    Disclosure: Nothing to disclose.

    Chief Editor

    Julian Katz, MD Clinical Professor of Medicine, Drexel University College of Medicine

    Julian Katz, MD is a member of the following medical societies: American College of Gastroenterology,

    American College of Physicians,American Gastroenterological Association,American Geriatrics Society ,

    American Medical Association,American Society for Gastrointest inal Endoscopy,American Society of Law,

    Medicine & Ethics,American Trauma Society ,Association of American Medical Colleges, and Physicians for

    Social Responsibility

    Disclosure: Nothing to disclose.

    References

    1. Dupont HL, Edelman R, Kimmey M. Infectious diarrhea: from E coli to Vibrio. Patient Care. 1990;30:18-43.

    2. Al-Abri SS, Beeching NJ, Nye FJ. Traveller's diarrhoea. Lancet Infect Dis. Jun 2005;5(6):349-60.

    [Medline].

    3. Moralez EI, Lofland D. Shigellosis with resultant septic shock and renal failure. Clin Lab Sci. Summer

    2011;24(3):147-52. [Medline].

    4. Khan WA, Griffiths JK, Bennish ML. Gastrointest inal and extra-intestinal manifestations of childhood

    shigellosis in a region where all four species of Shigella are endemic. PLoS One. 2013;8(5):e64097.

    [Medline].

    5. Kroser JA, Metz DC. Evaluation of the adult patient with diarrhea. Prim Care. Sep 1996;23(3):629-47.[Medline].

    6. Banerjee S, LaMont JT. Treatment of gastrointestinal infections. Gastroenterology. Feb 2000;118(2 Suppl

    1):S48-67. [Medline].

    http://reference.medscape.com/medline/abstract/10868898http://reference.medscape.com/medline/abstract/8888349http://reference.medscape.com/medline/abstract/23691156http://reference.medscape.com/medline/abstract/21905580http://reference.medscape.com/medline/abstract/15919621http://www.psr.org/http://www.aamc.org/http://www.amtrauma.org/http://www.aslme.org/http://www.asge.org/http://www.ama-assn.org/http://www.americangeriatrics.org/http://www.gastro.org/http://www.acponline.org/http://www.acg.gi.org/http://www.sgim.org/http://www.acponline.org/http://www.alphaomegaalpha.org/http://www.shea-online.org/http://www.iasociety.org/index.asphttp://www.idsociety.org/http://www.thoracic.org/http://www.asm.org/http://www.ama-assn.org/http://www.acponline.org/http://www.acponline.org/http://www.acpe.org/http://www.chestnet.org/
  • 7/27/2019 Shigellosis Treatment

    3/3

    10/15/13 Shigellosis Treatment & Management

    emedicine.medscape.com/article/182767-treatment 3/3

    Medscape Reference 2011 WebMD, LLC

    7. Murphy GS, Bodhidatta L, Echeverria P, et al. Ciprofloxacin and loperamide in the treatment of bacillary

    dysentery.Ann Intern Med. Apr 15 1993;118(8):582-6. [Medline].

    8. Wolf DC, Gianella RA. Invasive pathogens. Consultations in Gastroenterology. 1996;381-384.

    9. Sivapalasingam S, Nelson JM, Joyce K, et al. High prevalence of antimicrobial resistance among Shigella

    isolates in the United States tested by the National Antimicrobial Resistance Monitoring System from

    1999 to 2002.Antimicrob Agents Chemother. Jan 2006;50(1):49-54. [Medline].

    10. Vinh H, Anh VT, Anh ND, Campbell JI, Hoang NV, Nga TV, et al. A multi-center randomized trial to

    assess the efficacy of gatifloxacin versus ciprofloxacin for the treatment of shigellosis in Vietnamese

    children. PLoS Negl Trop Dis. Aug 2011;5(8):e1264. [Medline]. [Full Text].

    11. Policar M. Shigellosis . In: Ferri's Clinical Advisor: Instant Diagnosis and Treatment. 2005:752-754.

    12. Gu B, Ke X, Pan S, Cao Y, Zhuang L, Yu R, et al. Prevalence and trends of aminoglycoside resistance in

    Shigella worldwide, 1999-2010. J Biomed Res. Mar 2013;27(2):103-15. [Medline]. [Full Text].

    13. Taneja N. Changing epidemiology of shigellosis and emergence of ciprofloxacin-resistant Shigellae in

    India. J Clin Microbiol. Feb 2007;45(2):678-9. [Medline].

    http://reference.medscape.com/medline/abstract/17122011http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602868/http://reference.medscape.com/medline/abstract/23554801http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3149021/http://reference.medscape.com/medline/abstract/21829747http://reference.medscape.com/medline/abstract/16377666http://reference.medscape.com/medline/abstract/8452323