sen - nastava iz predmeta · mef fiziologija i kat a practicum p7 - problem solving izv. prof. dr....

UNIVERSITY OF ZAGREB SCHOOL OF MEDICINE

Plan of the course

Physiology

Academic year 2019/2020

izv. prof. dr. sc. Vladiana Crljen

I. COURSE AIMS

The overall aim of the Physiology course is to increase understanding the fundamental mechanisms of how cells and organsystems function, how they are regulated under normal physiological conditions and also how their function is changed inpathological conditions, since some diseases could arise directly from abnormalities in their regulation.

Lecture hours: 33

Seminar hours: 102

Practical hours: 50

Total hours: 185

ECTS 21.0

II. COURSE STRUCTURE

Course hours:

Lectures: 33

Seminar: 102

Practicum: 50

Total hours: 185

Physiology curriculum is organized into learning units based on major body systems and functions as:

Cell, muscle physiology, cardiovascular physiology, respiratory physiology, physiology of flying and diving, renalphysiology, gastrointestinal physiology, metabolism and thermoregulation, physiology of the endocrine system, physiologyof the pregnancy and lactation, fetal and newborn physiology, physiology of the sport.

III. PLAN OF THE COURSE AND COURSE SCHEDULE

BLOCKS OF THE COURSE

Number of blocks: 1Blocknumber Start End

1. 20.1.2020 7.4.2020

BLOCKS OF THE COURSE SHEME

Block 1

Date Time Group Coursehours type Theme Teaching staff

Monday20.1.2020.

08:00-08:45;MEF FiziologijaPredavaonica

ALL Exam L1 - INTRODUCING THE PHYSIOLOGYCOURSE

izv. prof. dr. sc.Vladiana Crljen


ALL Exam L2 - INTRODUCTION AND MEMBRANETRANSPORT

izv. prof. dr. sc.Mirza Žižak


ALL Lectures L3 - ELECTRICAL PROPERTIES OF THEMEMBRANE

prof. dr. sc. HrvojeBanfić


A Seminar S1 - CELL izv. prof. dr. sc.Mirza Žižak


B Seminar S1 - CELL izv. prof. dr. sc.Mirza Žižak

Tuesday21.1.2020.


ALL Lectures L4 - SMOOTH MUSCLE prof. dr. sc. HrvojeBanfić

09:45-12:00;MEFKompjutorskaučionica

A Practicum P1 - MEMBRANE POTENTIAL part 1

dr. sc. Alan Šućur,dr. sc. Nikola Habek,izv. prof. dr. sc.Tomislav Kelava


B Practicum P1 - MEMBRANE POTENTIAL part 1

dr. sc. Hrvoje Lalić,dr. sc. Darja Flegar,izv. prof. dr. sc.Mirza Žižak


A Seminar S2 - MUSCLE prof. dr. sc. HrvojeBanfić


B Seminar S2 - MUSCLE prof. dr. sc. HrvojeBanfić

Wednesday22.1.2020. 10:00-12:15;

MEFKompjutorskaučionica

B Practicum P1 - MEMBRANE POTENTIAL part 2

izv. prof. dr. sc.Mirza Žižak, dr. sc.Alan Šućur, izv.prof. dr. sc.Tomislav Kelava


B Seminar S3 - HEART I izv. prof. dr. sc.Mirza Žižak


A Practicum P1 - MEMBRANE POTENTIAL part 2dr. sc. Hrvoje Lalić,dr. sc. Alan Šućur,dr. sc. Nikola Habek


A Seminar S3 - HEART I izv. prof. dr. sc.Mirza Žižak

Thursday23.1.2020.


A Seminar S5 - ECG izv. prof. dr. sc.Mirza Žižak


ALL Lectures L5 - INTORDUCING CARDIOVASCULARSYSTEM



B Seminar S5 - ECG izv. prof. dr. sc.Mirza Žižak

Friday24.1.2020.


A Seminar S4 - HEART II dr. sc. Hrvoje Lalić

10:30-13:30;MEF Fiziologija Ikat A Practicum P2 - ECG, RR

izv. prof. dr. sc.AleksandraDugandžić, dr. sc.Nikola Habek, dr. sc.Alan Šućur


B Seminar S4 - HEART IIizv. prof. dr. sc.Vesna LukinovićŠkudar


13:30-16:30;MEF Fiziologija Ikat B Practicum P2 - ECG, RR

izv. prof. dr. sc.AleksandraDugandžić, dr. sc.Nikola Habek, dr. sc.Vilma Dembitz

Monday27.1.2020.


A Seminar S6 - INTEGRATION I (Cell, Electricalproperties of the membrane, Heart) dr. sc. Darja Flegar


B Seminar S6 - INTEGRATION I (Cell, Electricalproperties of the membrane, Heart) dr. sc. Darja Flegar

Tuesday28.1.2020.

08:00-08:45;MEF Biološka ALL Seminar S6 - INTEGRATION I (Cell, El. prop. of the

membrane, Heart)/TESTizv. prof. dr. sc.Tomislav Kelava

08:00-08:45;MEF Novavijećnica

ALL Seminar S6 - INTEGRATION I (Cell,El. prop. of themembrane, Heart)/ TEST dr. sc. Darja Flegar


ALL Lectures L6 - INTRODUCING CIRCULATION;LAPLACE LAW



A Seminar S7 - C IRCULATION I- Arterial pressureand circulation

izv. prof. dr. sc.Tomislav Kelava


B Seminar S7 - C IRCULATION I- Arterial pressureand circulation

izv. prof. dr. sc.Tomislav Kelava

Wednesday29.1.2020.


B Seminar S8 - MICROCIRCULATIONizv. prof. dr. sc.AleksandraDugandžić


A Seminar S8 - MICROCIRCULATIONizv. prof. dr. sc.AleksandraDugandžić

15:30-18:30;MEF FiziologijaVježbaonica A Practicum P5 - PLETISMOGRAPHY, POLYGRAPHY

dr. sc. Hrvoje Lalić,izv. prof. dr. sc.Tomislav Kelava, dr.sc. Nikola Habek

Thursday30.1.2020.


B Seminar S9 - C IRCULATION III-CO & venousreturn, spec.org. circulation



ALL Lectures L7 - AUTONOMIC NERVOUS SYSTEM doc. dr. sc. MarijaRenić


A Seminar S9 - C IRCULATION III - CO & venousreturn, spec.org. circulation


Friday31.1.2020.


A Seminar S10 - C IRCULATION II Regulation ofarterial pressure



B Seminar S10 - C IRCULATION II Regulation ofarterial pressure


14:30-17:30;MEF FiziologijaVježbaonica B Practicum P5 - PLETISMOGRAPHY, POLYGRAPHY

dr. sc. Alan Šućur,dr. sc. Darja Flegar,dr. sc. VilmaDembitz

Monday3.2.2020.

11:15-12:45;MEFWickerhauser

ALL Lectures L8 - BLOOD CLOTTING izv. prof. dr. sc.Mirza Žižak

13:00-15:15;MEF Fiziologija Ikat A Practicum P4 - BLOOD CLOTTING

dr. sc. VilmaDembitz, dr. sc. AlanŠućur, dr. sc. DarjaFlegar


16:30-18:45;MEF Fiziologija Ikat B Practicum P4 - BLOOD CLOTTING

izv. prof. dr. sc.Vesna LukinovićŠkudar, dr. sc.Vilma Dembitz, dr.sc. Nikola Habek

Tuesday4.2.2020.


ALL Lectures L9 - ERYTHROCYTE, ANEMIA ANDPOLYCYTHEMIA

izv. prof. dr. sc.Vesna LukinovićŠkudar

09:00-12:45;MEF FiziologijaVježbaonica A Practicum P3 - ERYTHROCYTE COUNT, Ht, Hb

izv. prof. dr. sc.Vesna LukinovićŠkudar, dr. sc.Nikola Habek, dr. sc.Vilma Dembitz

13:00-16:45;MEF FiziologijaVježbaonica B Practicum P3 - ERYTHROCYTE COUNT, Ht, Hb

izv. prof. dr. sc.Vesna LukinovićŠkudar, dr. sc.Darja Flegar, DinoŠisl, dr. med.

Wednesday5.2.2020.


A Seminar S11 - INTEGRATION II(C IRCULATION) izv. prof. dr. sc.Mirza Žižak


B Seminar S11 - INTEGRATION II (C IRCULATION) izv. prof. dr. sc.Mirza Žižak

Friday7.2.2020.

15:30-16:15;MEF Čačković ALL Seminar S11 - INTEGRATION II (CVS)/TEST izv. prof. dr. sc.

Mirza Žižak15:30-16:15;MEF FiziologijaVježbaonica

ALL Seminar S11 - INTEGRATION II (CVS)/TEST dr. sc. Nikola Habek

Tuesday11.2.2020. 08:30-10:00;

MEF Čačković ALL Exam COLLOQUIUM P1izv. prof. dr. sc.Vesna LukinovićŠkudar


ALL Exam COLLOQUIUM P1 izv. prof. dr. sc.Tomislav Kelava


ALL Lectures L10 - INTRODUCING RESPIRATORYSYSTEM

prof. dr. sc. DoraVišnjić

Wednesday12.2.2020.

08:30-10:45;MEF Mašek A Seminar S12 - RESPIRATION I - Pulmonary

ventilation and circulationprof. dr. sc. DoraVišnjić


B Seminar S12 - RESPIRATION I - Pulmonaryventilation and circulation


14:00-17:00;MEF FiziologijaVježbaonica B Practicum P6 - SPIROMETRY

izv. prof. dr. sc.Vesna LukinovićŠkudar, dr. sc.Hrvoje Lalić, dr. sc.Darja Flegar

Thursday13.2.2020.


B Seminar S13 - RESPIRATION II - Principles of gasexchange; CO2 & O2 transport



A Seminar S13 - RESPIRATION II - Principles of gasexchange; CO2 & O2 transport


14:30-17:30;MEF FiziologijaVježbaonica A Practicum P6 - SPIROMETRY

izv. prof. dr. sc.Vesna LukinovićŠkudar, dr. sc.Nikola Habek, DinoŠisl, dr. med.

Friday14.2.2020.


A Seminar S14 - RESPIRATION III - Regulation ofrespiration



ALL Lectures L11 - FLYING AND DIVINGizv. prof. dr. sc.AleksandraDugandžić



B Seminar S14 - RESPIRATION III - Regulation ofrespiration


Monday17.2.2020.


A Seminar S15 - INTEGRATION III prof. dr. sc. DoraVišnjić


B Seminar S15 - INTEGRATION III prof. dr. sc. DoraVišnjić

Tuesday18.2.2020.

08:15-09:00;MEF Čačković ALL Seminar S15 - INTEGRATION III (Respiratory

system)/TESTprof. dr. sc. DoraVišnjić

08:15-09:00;MEF FiziologijaVježbaonica

ALL Seminar S15 - INTEGRATION III (Respiratorysystem)/TEST



ALL Lectures L12 - INTRODUCING RENAL SYSTEM prof. dr. sc. HrvojeBanfić

Wednesday19.2.2020.


A Seminar S16 - BODY FLUIDSizv. prof. dr. sc.Vesna LukinovićŠkudar


B Seminar S16 - BODY FLUIDSizv. prof. dr. sc.Vesna LukinovićŠkudar

Thursday20.2.2020.

08:00-10:15;MEF Mašek A Seminar S17 - KIDNEY I - Structure, GFR,

C learanceizv. prof. dr. sc.Mirza Žižak

10:30-12:45;MEF Mašek B Seminar S17 - KIDNEY I - Structure, GFR,

C learanceizv. prof. dr. sc.Mirza Žižak

Friday21.2.2020.

08:00-10:15;MEF Mašek A Seminar S18 - KIDNEY II-Tub trans.&proc.,Reg.of

K,Ca,HPO4&Mgizv. prof. dr. sc.Vladiana Crljen

10:30-11:15;MEF Fiziologija Ikat B Practicum P7 - PROBLEM SOLVING

izv. prof. dr. sc.Vladiana Crljen, dr.sc. Alan Šućur, dr.sc. Vilma Dembitz


B Practicum P7 - PROBLEM SOLVING


12:45-13:30;MEF Fiziologija Ikat B Practicum P7 - PROBLEM SOLVING



B Seminar S18 - KIDNEY II-Tub trans.&proc.,Reg.ofK,Ca,HPO4&Mg


Monday24.2.2020. 08:00-08:45;

MEF Fiziologija Ikat

A Practicum P7 - PROBLEM SOLVING



A Practicum P7 - PROBLEM SOLVING


10:15-11:00;MEF Fiziologija Ikat A Practicum P7 - PROBLEM SOLVING



A Seminar S19 - KIDNEYIII-Regulation of ECV &osmolarity, Urine concetration




B Seminar S19 - KIDNEYIII-Regulation of ECV &osmolarity, Urine concentration

dr. sc. VilmaDembitz

Tuesday25.2.2020.


ALL Lectures L13 - ACID BASE BALANCEizv. prof. dr. sc.AleksandraDugandžić


A Seminar S20 - ACID BASE BALANCE prof. dr. sc. HrvojeBanfić


B Seminar S20 - ACID BASE BALANCE prof. dr. sc. HrvojeBanfić

Wednesday26.2.2020.


A Seminar S21 - INTEGRATION IV (Renal system) izv. prof. dr. sc.Vladiana Crljen

10:45-12:15;MEF Mašek B Seminar S21 - INTEGRATION IV (Renal sytem) izv. prof. dr. sc.

Vladiana CrljenThursday27.2.2020.

10:00-10:45;MEF Čačković ALL Seminar S21 - INTEGRATION IV (Renal

system)/TESTizv. prof. dr. sc.Vladiana Crljen


ALL Seminar S21 - INTEGRATION IV (Renalsystem)/TEST dr. sc. Alan Šućur

Tuesday3.3.2020.

09:00-10:30;MEF Čačković ALL Exam COLLOQUIUM P2 dr. sc. Darja Flegar


ALL Exam COLLOQUIUM P2 dr. sc. Alan Šućur


ALL Lectures L14 - INTRODUCING GASTROINTESTINALPHYSIOLOGY


Wednesday4.3.2020.


A Seminar S22 - GI I - Principles of GI function,motility, nervous control, circulation



B Seminar S22 - GI I Principles of GI function,motility, nervous control, circulation


Thursday5.3.2020.


A Seminar S23 - GI II - Secretory functions,digestion and absorption



B Seminar S23 - GI II - Secretory functions,digestion and absorption


Friday6.3.2020.


A Seminar S24 - GI III - Metab. of carbohydrates,lipids and proteins



B Seminar S24 - GI III - Metab. of carbohydrates,lipids and proteins


Monday9.3.2020.


A Seminar S25 - TERMOREGUALTION, METABOLISM izv. prof. dr. sc.Vladiana Crljen


B Seminar S25 - TERMOREGUALTION, METABOLISM izv. prof. dr. sc.Vladiana Crljen

Tuesday10.3.2020.


A Seminar S26 - INTEGRATION V (Gastrointestinalsystem)



B Seminar S26 - INTEGRATION V (Gastrointestinalsystem)



11:00-14:00;MEF Fiziologija Ikat A Practicum P8 - BASAL METABOLISM

izv. prof. dr. sc.Vladiana Crljen, dr.sc. Hrvoje Lalić, dr.sc. Alan Šućur

14:30-17:30;MEF Fiziologija Ikat B Practicum P8 - BASAL METABOLISM

izv. prof. dr. sc.Vladiana Crljen, dr.sc. Hrvoje Lalić, dr.sc. Alan Šućur

Wednesday11.3.2020. 08:15-09:00;

MEF Čačković ALL Seminar S26 - INTEGRATION V (GI SYSTEM)/TESTizv. prof. dr. sc.Vesna LukinovićŠkudar

08:15-09:00;MEF Biološka ALL Seminar S26 - INTEGRATION V (GI SYSTEM)/TEST dr. sc. Nikola Habek

09:30-11:00;MEF Čačković ALL Lectures L15 - INTRODUCING ENDOCRINE SYSTEM prof. dr. sc. Dora

VišnjićThursday12.3.2020.

08:00-10:15;MEF Biološka A Seminar S27 - PITUITARY GLAND dr. sc. Nikola Habek

10:30-12:45;MEF Biološka B Seminar S27 - PITUITARY GLAND dr. sc. Nikola Habek

Friday13.3.2020.


A Seminar S28 - THYROID GLANDizv. prof. dr. sc.Vesna LukinovićŠkudar


B Seminar S28 - THYROID GLANDizv. prof. dr. sc.Vesna LukinovićŠkudar

11:00-14:00;MEF Fiziologija Ikat A Practicum P9 - THYROID HORMONE & O2

CONSUMPTION IN RATS

dr. sc. Darja Flegar,dr. sc. Hrvoje Lalić,dr. sc. VilmaDembitz

14:30-17:30;MEF Fiziologija Ikat B Practicum P9 - THYROID HORMONE & O2

CONSUMPTION IN RATS

dr. sc. Hrvoje Lalić,Barbara Tomić, dr.med., izv. prof. dr.sc. Vladiana Crljen

Monday16.3.2020.


A Seminar S29 - CALCIUM, PHOSPHATE BALANCE prof. dr. sc. DoraVišnjić


B Seminar S29 - CALCIUM, PHOSPHATE BALANCE prof. dr. sc. DoraVišnjić

12:00-15:00;MEF Fiziologija Ikat A Practicum P10 - THORN

dr. sc. VilmaDembitz, dr. sc. AlanŠućur, dr. sc. HrvojeLalić

Tuesday17.3.2020.


B Seminar S30 - ADRENAL GLAND dr. sc. Nikola Habek


A Seminar S30 - ADRENAL GLAND dr. sc. Nikola Habek

10:30-13:30;MEF Fiziologija Ikat B Practicum P10 - THORN

izv. prof. dr. sc.Vladiana Crljen, dr.sc. Alan Šućur, dr.sc. Hrvoje Lalić

Wednesday18.3.2020.


B Seminar S31 - REPRODUCTIVE PHYSIOLOGY ANDMALE HORMONES

izv. prof. dr. sc.AleksandraDugandžić


A Seminar S31 - REPRODUCTIVE PHYSIOLOGY ANDMALE HORMONES


Thursday19.3.2020.


B Seminar S32 - REPRODUCTIVE PHYSIOLOGY ANDFEMALE HORMONES




A Seminar S32 - REPRODUCTIVE PHYSIOLOGY ANDFEMALE HORMONES


Monday23.3.2020.


A Seminar S33 - BLOOD GLUCOSE, INSULIN,GLUCAGON


10:30-13:30;MEF Fiziologija Ikat A Practicum P11 - OGTT

dr. sc. Hrvoje Lalić,Barbara Tomić, dr.med., dr. sc. AlanŠućur

Tuesday24.3.2020.


B Seminar S33 - BLOOD GLUCOSE, INSULIN,GLUCAGON


10:30-13:30;MEF Fiziologija Ikat B Practicum P11 - OGTT

dr. sc. Hrvoje Lalić,dr. sc. VilmaDembitz, dr. sc. AlanŠućur

Wednesday25.3.2020.


ALL Lectures L16 - PREGNANCY AND LACTATIONizv. prof. dr. sc.Vesna LukinovićŠkudar


ALL Lectures L17 - FETAL AND NEWBORN PHYSIOLOGYizv. prof. dr. sc.AleksandraDugandžić

12:00-15:00;MEF FiziologijaVježbaonica A Practicum P12 - ÅSTRAND

dr. sc. VilmaDembitz, dr. sc.Hrvoje Lalić, DinoŠisl, dr. med.

15:15-18:15;MEF FiziologijaVježbaonica B Practicum P12 - ÅSTRAND

dr. sc. Darja Flegar,dr. sc. VilmaDembitz, BarbaraTomić, dr. med.

Thursday26.3.2020. 08:00-09:30;

MEFWickerhauser

A Seminar

S34 - INTEGRATION VI (Endocrinesystem; Pregnancy and lactation, Fetaland newborn physiology; Sportsphysiology)

dr. sc. Nikola Habek


ALL Lectures L18 - SPORTS PHYSIOLOGY prof. dr. sc. HrvojeBanfić

11:30-13:00;MEFWickerhauser B Seminar

S34 - INTEGRATION VI (Endocrinesystem; Pregnancy and lactation, Fetaland newborn physiology; Sportsphysiology)

dr. sc. Nikola Habek

Friday27.3.2020.

10:00-10:45;MEF Čačković ALL Seminar S34 - INTEGR VI (End.S.;Preg.Lac.;

Fet.New; Spor.) /TESTizv. prof. dr. sc.Vladiana Crljen


ALL Seminar S34 - INTEGR VI (End.S.;Preg.Lac.;Fet.New; Spor.) /TEST


Tuesday31.3.2020.

10:00-11:30;MEF Biološka ALL Exam COLLOQUIUM P3 izv. prof. dr. sc.

Mirza Žižak10:00-11:30;MEF Novavijećnica

ALL Exam COLLOQUIUM P3 dr. sc. Nikola Habek

Friday3.4.2020.

13:00-16:45;MEF Čačković ALL Exam COLLOQUIUM P1 OR P2 prof. dr. sc. Hrvoje

BanfićThursday2.7.2020.


ALL Exam Examizv. prof. dr. sc.Tomislav Kelava, dr.sc. Alan Šućur

Tuesday14.7.2020.


ALL Exam Examizv. prof. dr. sc.Tomislav Kelava, dr.sc. Alan Šućur

Tuesday1.9.2020.


ALL Exam Examdr. sc. Darja Flegar,izv. prof. dr. sc.Vladiana Crljen


Tuesday15.9.2020.


ALL Exam Examdr. sc. Darja Flegar,izv. prof. dr. sc.Vladiana Crljen


LIST OF LECTURERS AND TEACHING STAFF

Prof. Hrvoje Banfić , Head of the Departement

Prof. Dora Višnjić

Assoc. Prof. Mirza Žižak

Assoc. Prof. Aleksandra Sinđić

Assoc. Prof. Vladiana Crljen

Assoc. Prof. Vesna Lukinović Škudar

Assoc. Prof. Tomislav Kelava

Assist Prof Marija Renić

Senior Instructor Hrvoje Lalić, MD, PhD

Senior Instructor Alan Šućur, MD, PhD

Senior Instructor Vilma Dembitz, MD, PhD

Instructor Darja Flegar, MD, MD, PhD

Instructor Nikola Habek, MD, PhD

Instructor Dino Šisl, MD

Instructor Barbara Tomić, MD

LIST OF EXAMINERS

Prof. Hrvoje Banfić

Prof. Dora Višnjić

Assoc. Prof. Mirza Žižak

Assoc. Prof. Aleksandra Dugandžić

Assoc. Prof. Vladiana Crljen

Assoc. Prof. Vesna Lukinović Škudar

Assoc. Prof. Tomislav Kelava

CONSULTATIONS

Prof. Hrvoje Banfić

Consultations: TUESDAY 16,00 - 18,00e-mail: [email protected].

Assoc. Prof. Vladiana CrljenConsultaions: WEDNESDAY 13,00-15,00e-mail: [email protected]

Prof. Dora VišnjićConsultations: MONDAY 14,00 - 16,00e-mail: [email protected]

Assoc. Prof. Mirza ŽižakConsultations: to be agreed

e-mail: [email protected]

Assoc. Prof. Aleksandra DugandžićConsultations: MONDAY 15,00-17,00 e-mail: [email protected]

Assoc. Prof. Vesna Lukinović-ŠkudarConsultations: FRIDAY 12,00 - 14,00e-mail: [email protected]

Assis. Prof. Marija Renić

Consultations: MONDAY 14,00-16,00


Assoc. Prof. Tomislav KelavaConsultations: THURSDAY 12,00 - 14,00


Senior Instructor Hrvoje Lalić, MD, PhD

Consultations: TUESDAY 14,00-16,00


Senior Instructor Alan Šućur, MD, PhDConsultations: THURSDAY 13,00-15,00


Senior Instructor Vilma Dembitz, MD, PhD

Consultations: WEDNESDAY 14,00-16,00


Instructor Darja Flegar, MD, PhDConsultations: WEDNESDAY 14,00-16,00


Instructor Nikola Habek, MD, PhD

Consultations: THURSDAY 12,00-14,00


Instructor Dino Šisl, MD

Consultations: TUESDAY 14,00-16,00


Instructor Barbara Tomić, MD

Consulatations: THURSDAY 14,00-16,00


Lectures:

1. Introducing Physiology course (1)

2. Introducing membrane transport (2)

3. Electrical properties of the membrane (2)

4. Smooth muscle (2)

5. Introducing cardiovascular system (2)

6. Introducing circulation; Laplace law (2)

7. Autonomic nervous system (1)

8. Blood clotting (2)

9. Erythrocytes, anemia and polycythemia (1)

10. Introducing respiratory system (2)

11. Flying and diving (2)

12. Introducing renal system (2)

13. Acid-base balance (2)

14. Introducing gastrointestinal physiology (2)

15. Introducing endocrine system (2)

16. Pregnancy and lactation (2)

17. Fetal and Newborn Physiology (2)

18. Sports Physiology (2)

Seminar topics:

S SEMINAR TITLE Theme Chapter

1 CELL (3) Cell & membrane potential 4, 5

2 MUSCLE (3)

Structure of skeletal, smooth muscle, mechanism of contraction,control of skeletal muscle contraction excitation – contractioncoupling, neuromuscular transmission, mechanics and energetic ofskeletal muscle contraction, smooth muscle

6,7,8

3 HEART I (3)Cardiac muscle characteristic;

Electrophysiology of heart

9 (p 106-109),

10

4 HEART II (3) Cardiac function, cardiac cycle, cardiac defects (heart sounds) 9, 23 (p 283-285)

5

6

ECG, VECTOR ANALYSIS(3)

INTEGRATION I (3)

Electrocardiogram (ECG);

Vector analysis

Cell, Electrical properties of the membrane, Heart

TEST

11, 12

4-12,

23 (p 283-285)

7

CIRCULATION I (3) Arterial pressure and circulation 14, 15

8 MICROCIRCULATION (3)Fluid dynamics, the microcirculation and lymphatic;

Local control of blood flow 16, 17

9 CIRCULATION III (3)

Cardiac output and venous return;

Coronary circulation, skeletal muscle circulation

20,

21 (p259-264)

10 CIRCULATION II (3) Regulation of arterial pressure 18, 19

11 INTEGRATION II (3)

Case: Hypovolemic shock* Case: Acute myocardial infarction*

TEST

14-20,

21 (p 259-264)

12 RESPIRATION I (3)Pulmonary ventilation;

Pulmonary circulation 38, 39

13 RESPIRATION II (3)Principles of gas exchange;

Oxygen and carbon dioxide transport 40, 41

14 RESPIRATION III (3) Regulation of respiration 42

15 INTEGRATION III (3)Case: Obstructive lung disease*

TEST

31, 38-42; 43 (p 549-551)

16 BODY FLUIDS ANDELECTROLYTES (3) Edema, hyperhidration, dehydration 25

17 KIDNEY I (3) Structure of kidney and nephrons, glomerular filtration rate; Renalhemodynamics; Renal clearance

26, 27 28 (p365-368)

18 KIDNEY II (3) Transport and processing properties of tubular segments;Regulation of potassium, calcium, phosphate and magnesium

28 (p 347-365), 30 (p 389-399)

19 KIDNEY III (3) Regulation of extracellular fluid volume and osmolarity; Urineconcentration and dilution; Micturation; Dialysis

29, 30 (p 401--408), 32 (p 427-429, p 440-441)

20 ACID–BASE BALANCE(3) Acid-Base Balance 31

21 INTEGRATION IV (3)

Case: Acute glomerulonephritis*

Case: Secondary arterial hypertension*

TEST

25-31 (32)

22 GASTROINTESTINALSYSTEM I (3)

Principles of gastrointestinal function: motility, nervous control,blood circulation;

Reflexes, Propulsion and mixing of food

63, 64

23 GASTROINTESTINALSYSTEM II (3)

Secretory functions;

Digestion and absorption 65, 66

24 GASTROINTESTINALSYSTEM III (3)

Metabolism of carbohydrates, lipids, and proteins;Bilirubin, bile secretion, carbohydrate, nitrogen, lipid and proteinmetabolism, conjugation and detoxification; Liver

68, 69, 70, 71

25 THERMOREGULATIONAND METABOLISM (3)

Dietary balances, regulation of feeding; Metabolic rate;

Regulation of body temperature 72, 73, 74

26 INTEGRATION V (3)Case: Gastrointestinal system*

TEST 63-74

27 PITUITARY GLANDHORMONES (3) Pituitary hormones 76

28 THYROID GLANDHORMONES (3) Thyroid metabolic hormones 77

29CALCIUM ANDPHOSPHATE BALANCE (3)

Calcium and phosphate metabolism, vitamin D;

PTH and Calcitonin

80

30ADRENOCORTICAL

HORMONES (3)

Mineralocorticoids;

Glucocorticoids 78

31

32

REPRODUCTIVE

PHYSIOLOGY I (3)

REPRODUCTIVE

PHYSIOLOGY II (3)

Male hormones

Female hormones

81, 82

33REGULATION OFBLOOD GLUCOSECONCENTRATION (3)

Insulin, glucagon, liver, skeletal muscle, cortisol, catecholamine,growth hormone 79

34 INTEGRATION VI (3)

Endocrine system, Insulin sensitivity and glucoseuptake, Pregnancy and lactation, Fetal and newborn physiology

TEST 76-82

PRACTICAL WORK:

Students will be introduced through practical work to diagnostic tests that are routinely used in medicine. Due toethical reasons some of the exercises will be performed on animals (laboratory rats). In that way we will also show ourstudents how to work with laboratory animals, what can be helpful in their future scientific work. In line with that, somepracticals are designed as scientific experiments. When it is possible, the animal experiments are replaced with computersimulation.

Practical work topics:

1. MEMBRANE POTENTIAL - PART 1 and 2 (6) - LMS, Gu. 4, 5

2. ECG. MEASURING ARTERIAL BLOOD PRESSURE. (4) - LMS, Gu 11, 12,

14 (p 172-175),

15 (180-184)

3. ERYTROCYTE COUNT. HAEMOGLOBIN. HEMATOCRIT. SEDIMENTATION RATE. (5) -

LMS, Gu 33

4. BLOOD CLOTTING TESTS (3) - LMS, Gu 37

5. PLETISMOGRAPHY, POLIGRAPHY (4) - LMS

6. SPIROMETRY (4) - LMS, Gu 38 (p 501-503); 43 (p 549-551)

7. PROBLEM SOLVING (model KIDNEY); ERYTROCYTE - MEMBRANE RESISTANCY (4)

- LMS,

Gu 26, 27,

28, 29

8. MEASURING THE RATE OF BASAL METABOLISM IN HUMAN. (4) - LMS, Gu 73

(p 905-909)

9. EFFECT OF THYROID HORMONE ON OXYGEN CONSUMPTION IN RAT (4) - LMS, Gu 77

(p 954-958)

10. THORN TEST. INDUCING THE HYPOCALCIEMIC TETANY IN RAT. (4) - LMS, Gu 80

(p 1001-1003)

11. GLUCOSE TOLERANS TEST. INSULIN INDUCED HYPOGLYCEMIA IN RAT (4) - LMS,

Gu 79

(p 993-999)

12. CHANGES IN CARDIOVASCULAR SYSTEM INDUCED BY MUSCLE WORK. ASTRAND. EMG (4)-

LMS

Students should come prepared to practicals. Description of each practical is given on the LMS. Also,students should read textbook (Guyton) to get ready for practical. Next to each practical listed above isgiven chapter(s) from textbook that should be studied in advance.

Šalata 3– Departement of Physiology

Lecture room (PL) and practical rooms (PP, PP2)

Lectures will take place in hall: Physiology lecture room (PL) or available lecture room (L) in main building

according to schedule

Seminars will take place in hall: Physiology lecture room (PL) or available lecture room (L) in main building

according to schedule

IV. EXAMINATIONS

IV.a. EXAM POLICY:

Exam questions will include material presented in lecture, assigned chapter readings and case studies distributed duringclass or posted on the course web site. Questions are multiple choice with only one correct answer. Each question accountsfor one point and there are no negative points.

Major colloquium quizzes

Three major colloquium quizzes will be held during the course. These quizzes are named P-1, P-2 and P-3 colloquium. Eachquiz is made up of 60 multiple choice questions equally distributed through textbook obligatory chapters.

Ph1 colloquium - includes general physiology, muscle physiology and the cardiovascularsystem (topics covered in lectures 1-9, seminars 1-11 andpractical work 1-5),Ph2 colloquium - includes physiology of kidney and respiratorysystem (topics covered inlectures 10-13, seminars 12-21 and practical work 6-7),Ph3 colloquium - includes physiology of digestive system, metabolism andendocrinology (topics covered inlectures 14-18,seminars 22-34 and practical work 8-12)

Students are given 90 minutes to complete each colloquium quiz. The score of each colloquium (P1-P3) contributes 33.3% tothe final grade at the end of the course.

IMPORTANT!

The Physiology department strongly encourages students to take and pass the major colloquium quizzes since it gives thestudents a great opportunity to “carry” the passing grades, achieved on each of three colloquium quizzes, from one toanother final exam.

(e.g. if student passed the Ph1 colloquium quiz he/she does not need to retake the Ph1 part of the final exam again duringcurrent academic year 2019./20.)

Bonus points (points earned on the small integration quizzes)

During the course students have obligation to take integration tests. There are six integration tests (after each physiologyfunctional unit there is integration test). Passing these tests gives our students opportunity to earn bonus points. Thebonus points earned during the course will be added to the total score of each of the corresponding colloquium quizzes (P1-P3). The bonus points will be added only if student earned 55% or more of the total score on the corresponding colloquiumquizzes

Final exam

The Final Exam is composed from two parts: written test and oral exam. To qualify for the oral exam student must pass thewritten exam.

Written test is composed of three parts: P1 + P2 + P3. Students are given 90 minutes to complete each test part with30 min break between each part.

Written part of exam has the elimination threshold. Student need to have average score 55% or more on each part of thewritten exam for passing level.

Oral exam is obligatory for the students who earned ≥55% and ≤85% of the total score on the written exam. Studentswho earned 85% and more of the total score on the written exam are exempt from taking oral exam. Oral exam willtake place the day after wrriten part of exam.

The final grade will depend on a grade given at the end of oral exam.

IV.b. GRADING CRITERIA

For passing the colloquiums and exams it is necessary to achieve a positive assessment of written part.

Grades will be determined on the basis of an objective standard of absolute difficulty of the test (called MPR) at:

≥85% of the total score on the test for excellence ,

75% of the total score on the test for very good,

65% of the total score on the test for good,

55% of the total score on the test for satisfactory.

IV.c. EXAM RESULTS:

Exam results will be posted on the Department of Physiology LMS page.

IV.d. ACADEMIC HONESTY

All students are expected to help to maintain an environment of academic honesty. The following behaviors are strictlyforbidden during the administration of the exam: talking, cell phone use, and passing of papers or notes. All backpacks,coats, cell phones, etc. are to be placed in the front of the room.

All students are required to hand-in the packet of exam questions with their name clearly indicated on first page of the exam.It is the responsibility of the student to make sure that the answers he/she wants graded are clearly marked on the scantronsheet with a #2 lead pencil.

B. Types of examination and examination dates

Mandatory written small colloquiums: Integration I 28.01.2020. ; Integration II 07.02.2020.; Integration III 18.02.2020.;integration IV 27.02.2020.; Integration V 11.03.2020.; Integration VI 27.03.2020.

Mandatory written big colloquiums: Colloquium P1 11.02.2020.; Colloquium P2 03.03.2020.; Colloquium P3 31.03.2020.

Eligibility Criteria

The criteria for application to take the final exam are as follows:

For the final exam can apply:

students who attended classes (seminars and practical) regularly,students who passed colloquium (for seminars and practical that were unattended)students who have signature in index for Physiology course

Colloquium for seminars and practical that were not attended is held by teachers who lead the seminar or practical thatstudent did not attend.

The policy for colloquium:

to be able to take colloquium student need to have the colloquium application sheet (student can get it in the roombeside the practicum room)the teacher’s signature in the colloquium application sheet is necessary to confirm that student successfully passedthe colloquium.

To get index signed student must regularly attend classes and pass all colloquiums for classes not attended.

Examination dates

Regular terms Date

Winter

07.04.2020.

16.12.2019.(Final exam for ac. year 2018./19.generation)

Summer

02.07.2020.

14.07.2020.

Autumn

01.09.2020.

15.09.2020.

V./I. LIST OF LECTURERS AND TEACHING STAFF

1. prof. dr. sc. Hrvoje Banfić

2. prof. dr. sc. Dora Višnjić

3. izv. prof. dr. sc. Mirza Žižak

4. izv. prof. dr. sc. Aleksandra Dugandžić

5. izv. prof. dr. sc. Vladiana Crljen

6. izv. prof. dr. sc. Vesna Lukinović Škudar

7. izv. prof. dr. sc. Tomislav Kelava

8. dr. sc. Hrvoje Lalić

9. dr. sc. Alan Šućur

10. dr. sc. Vilma Dembitz

11. dr. sc. Darja Flegar

12. dr. sc. Nikola Habek

13. doc. dr. sc. Marija Renić

14. Barbara Tomić, dr. med.

15. Dino Šisl, dr. med.

V./III UNTENURED LECTURERS:

V./II EXTERNAL ASSOCIATES:

VI. LITERATURE

A. Obligatory

Guyton AC, Hall JE: Textbook Of Medical Physiology, 13th Edition, 2016.

B. Additional

(in alphabetical order):

W. Boron and E. Boulpaep. Medical Physiology 3rd Edition, ISBN: 9781455743773

R.M. Berne and M.N. Levy. Physiology 7th Edition, ISBN:9780323393942

D.R. Bell. Core Concepts in Physiology. Lippincott-Raven, ISBN: 0-316-08868-4

Linda S. Costanzo. Physiology 6th Edition, ISBN: 9780323478816

Chapters from Guyton Textbook for exam:

Ph-1 includes chapters 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17, 18, 19, 20, 21, 23 (pages 283-285 untill "Valvular Leasions"), 33,34, 37, 61

Ph-2 includes chapters; 25, 26, 27, 28, 29, 30, 31, 38, 39, 40, 41, 42, 43 (pages 549-551 untill "Pathophysiology of SpecificPulmonary Abnormalities"), 44, 45

Ph-3 includes chapters: 63, 64, 65, 66, 68,69, 70, 71,72, 73, 74,75, 76, 77, 78, 79, 80, 81, 82, 83, 84, 85

Reading Assignments:

Students are expected to read the assigned chapters prior to coming to class. The exams will draw heavily upon materialdiscussed during lectures; however, students are still expected to master the material in the assigned chapters

NOTE:

MEF-Learning management System (MEF-LMS)

MEF-LMS is a platform designed to support teaching and learning at School of Medicine University of Zagreb.

MEF-LMS is used for the administration and delivery of the course materials, communication between students andteachers, students’ self assessments

Physiology course materials will be available on the Physiology LMS page

Intellectual Property

We ask you to respect the intellectual property of the authors of the course content. Course materials posted on thephysiology LMS page is copyrighted, by virtue of its publication on the internet, under the Millennium Act.

As such, students are reminded that it is illegal to copy or distribute any of these materials unless it is for personal use, oryou have obtained the consent of the authors of the copyrighted materials.

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