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ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
1
SCIENTIFIC PROGRAM - PRELIMINARY
Thursday, 27th of september 2018
Conference sessions
08.00 – 18.00
Check-in desk
Registration
09.00 – 12.00
Sala Forum
Oxidative stress evaluation – from basic mechanisms to assessment
of the biocompatibility and efficacy of some modern therapies
Coordinators: Simona Clichici, Adriana Filip, Şoimiţa Suciu
Oxidative stress and antioxydants
Şoimiţa Suciu In vitro methods of testing biocompatibility of new drugs, or
medical devices containing natural compounds.
Ioana Bâldea The relationship of oxidative stress with inflammatory
mediators.
Adriana Filip The oxidative stress in extreme conditions.
Daniela Mitrea Perspectives on Oxidative Stress in Relation to Carbon
Nanotubes.
Teodora Mocan Effects of the naturals and synthesis antioxidants in diabetic
neuropathy.
Irina Chiş Oxidative stress and air pollutants.
Cristina Bidian Interactions between antioxydants and cytostatic drugs.
Diana Olteanu
12.00 – 15.30
Check-in desk
12.00-14.00
12.00-17.00
Registration
At the Physiology Discipline, Clinicilor street no. 1-3
Workshop (hands-on): Stem cells in regenerative medicine Trainers: Ioana Bâldea, Remus Moldovan
At the Physiology Discipline, Clinicilor street no. 1-3
Workshop (hands-on) : Modern Trends in Testing of
Digestive Transit of Natural and Synthetic Materials
Trainers: Teodora Mocan, Simona Clichici
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
2
12.00-14.00
At the Center of Practical Skills and Simulation in Medicine,
Marinescu street, no. 23.
Workshop (hands-on) : Ultrasonophysiology – using
ultrasonography as a technique for the study of the
Physiology
Trainers: Oana Hoteiuc, Claudiu Bădulescu, Irina Chiş
15.30 – 17.40
Forum Room
Workshop: Modern trends in experimental research - ethical and
legal issues
Chairmen: Coman Cristin, Marcus Ioan, Sevastre Bogdan,
Sevastre-Berghian Alexandra, Maria Aluaş
Legislation on animal experimentation in romania
Coman Cristin
Reporting of severity in animal experimentation projects –a
practical approach
Bogdan Sevastre
Stem cells research and therapy – ethical and legal issues
Maria Aluaş
17.40 – 18.00
Foaier
Coffee break
18.00 – 19.15
Forum Room
OPENING CEREMONY
Prof. Dr. Simona Clichici - President of the Conference
Prof. Dr. Anca Buzoianu - Dean of the Faculty of Medicine, Cluj-Napoca
Prof. Dr. Carmen Panaitescu - President of the Romanian Society of
Physiology
Prof. Dr. Adriana Mureșan – Honorary President of the Conference
Prof. Dr. Dragan Djuric - President, Assembly, Serbian Physiological Society
Prof. Dr. Nina Belova – on behalf of the Bulgarian Society of Physiology
Prof. Dr. Janos Almassy - on behalf of the Hungarian Society of Physiology
New perspectives on mechanisms of communication in
biological systems
Leon Zăgrean
19.30 – 21.00
Atrium Room
Welcome reception
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
3
FRIDAY, 28th of september 2018
08.30 – 09.00
Forum Room
General Assembly of The Romanian Society of Physiology (SRF)
09.00 – 10.30
Forum Room
SESSION 1: Basic mechanisms with clinical impact
Chairmen: Dragan Djuric, Simona Clichici, Carmen Panaitescu
Acute And Subchronic Methionine Overload Induce Different
Cardiovascular Effects In Rats: Non-Homocysteine Dependent
Mechanisms
Dragan Djuric
The Role Of Stem Cells In Regenerative Medicine
Virgil Păunescu
Arterial Stiffness And Haemodynamics
Nina Belova
The Role Of Exercise In Cardiovascular Homeostasis: From
Basic Science To Applied Clinical Investigations
Vladimir Jakovljevic
How does dantrolene inhibit the ryanodine receptor?
Janos Almassy
Effects Of Polyphenolic Compound And Statin Therapy In
Experimental Metabolic Syndrome
Olga Pechanova
10.30 – 11.00
Foaier
Pause/Coffee break
11.00 – 12.00
Forum Room
SESSION 2: Back to Physiology: Reverting the Allergic Response
Chairmen: Virgil Păunescu, Carmen Panaitescu
Ragweed pollen allergy – patterns of sensitization
Carmen Panaitescu
Recombinant allergens for improving Ambrosia allergy
diagnosis and therapy
Kuan Wei Chen
Recombinant Amb a 8, a candidate for the improvement of
ragweed allergy diagnosis and therapy
Maria Roxana Buzan
12.00 – 13.00
Forum Room
Early life stress and health: a physiological perspective
Andrei Miu
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
4
11.00 – 13.00
Ambasador Room
SESSION 3: Advances in cardiac and vascular physiology – from
mechanism to clinical application
Chairmen: Danina Muntean, Alina Scridon, Ionela Serban
Monoamine oxidases are sources of vascular oxidative stress in
the setting of inflammation in patients undergoing elective
abdominal surgery
Adrian Sturza
Interrelations between pulse wave speed and ECG – A possible
cuffless measurement method for systolic blood pressure?
Marcel Perian
An experimental model for Angiotensin II-induced arterial
hypertension
Minela Maranduca
The impact of chronic ivabradine administration on
transesophageal pacing-induced atrial fibrillation
Balan Alkora
Effects of chronic ivabradine administration on ventricular
arrhythmogenesis in in vivo rats
Maria Flavia Radulescu
Chronic ivabradine administration prevents exaggerated heart
rate lowering during acute in vivo parasympathetic stimulation
Vasile Bogdan Halațiu
Bisphenol A – effects on hemodynamic and autonomic
parameters and on cardiac arrhythmogenesis in healthy female
rats
Saleh Samer
Isoproterenol induced myocardial infarction in rats: dose
identification
Paul Boarescu
13.00 – 14.00
Atrium Room
Pause/Lunch
14-15
Forum Room
SESSION 4: From intracellular signalling pathways to clinical
relevance
Chairmen: Şoimiţa Suciu, Remus Orăsan
New insights in receptors`signalling
Anca Buzoianu
Crosstalk between monoamine oxidase and vitamin D: new
roles for old friends
Danina Munteanu
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
5
Is Psoriasis Vulgaris a Skin Disease or a Multisystem
Generalized Disease?
Remus Orasan
14.00-15.00
Ambasador Room
AstraZeneca Symposium: Regandirea managementului astmului - de la
endotip la tratament
Endotipurile de astm –fundamentul terapiei personalizate in
astm
Ioana Agache
Regandirea strategiei terapeutice in astmul usor: combinatia de
corticosteroid inhalator si β2-agonist cu durata lunga de actiune
si efect rapid, alternativa noua la terapia conventionale
Carmen Panaitescu
Alegerea corecta a produsului terapeutic biologic in astm
Laura Marusciac
15.00-15.30 Poster Session (Posters 1 – 10)
Chairmen: Adrian Bălșeanu, Carmen Tatu, Ioana Bâldea
15.30 – 17.00
Forum Room
SESSION 5: Neurocognitive and behaviour functions – physiological
mechanisms and pathological impact
Chairmen: Zvezdana Kojic, Veronica Sfredel, Adriana Filip
Functional neuroimaging a review of the preclinical and
clinical state of the art
Sinisa Ristic
Optical properties of blood in a group of subjects with ischemic
stroke
Veronica Sfredel
Old roads with new connections: landmarks in diagnosis and
pathophysiological mechanisms in rare diseases, focus on
treatable neuro-metabolic disorders
Romana Vulturar
Aquaporin 4 and the central nervous system glia scaring
Cătălin Bogdan
Chloride transportation modulation impacts on neuronal
viability in mature hippocampal cultures exposed to oxygen-
glucose deprivation and reoxygenation
Diana Maria Chitimus
Maternal high-fat diet influences the immature rat
hippocampus exposed to perinatal asphyxia
Ieșanu Mara
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
6
Characterization and biological effects of hypericum extracts
on anxiety-like behavior, oxidative stress and inflammation in
rats
Alexandra Berghian
Neuroprotective treatments in experimental hypoxic-ischemic
encephalopathy
Alina Toader
15.30 – 17.00
Sala Ambasador
Session 5: New insights in physiological and pathological
mechanisms: from experimental to clinical approach
Chairmen: Janos Almassy, Anca Bojan, Ionela Șerban
The role of melanin concentrating hormone (mch) in the
pathomechanism of childhood obesity and diabetes mellitus
Rita Kiss
Principles of immunotherapy in hematologic malignancies
Anca Bojan
The sphingolipids signalling pathway - new diagnosis tool of
hepatocellular carcinoma
Iuliana Nenu
Influence of sound on the reproductibility – experimental
results on animals
Coman Cristin
Antiproliferative and antioxidant effects of pomace extracts
from fetească neagră and pinot noir cultivars
Pârvu Alina
MPMoIII as criteria for interhospital transportation of
polytrauma patients. Pilot study
Arnaut Oleg
Functional changes of the retina in diabetic patients
Cornelia Tănasie
Thrombophilia screening in pregnancy - is useful or not?
Liliana Hurjui
17.00 – 17.30
Foaier
Pause/Coffee
17.30 – 19.00
Forum Room
Session 5: Advances in oral cavity physiology: materials, mechanisms
and their clinical impact
Chairmen: Zvezdana Kojic, Anca Bădărau, Adriana Filip
Newly-designed alpha tricalcium phosphate cement:
biocompatibility study
Zvezdana Kojic
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
7
Tooth physiology – terra incognita
Vasile Zagnat
The organic growth factors role in the oral cavity level
Raluca Jipu
Researches concerning the impact of the salivary secretion
dysfunctions in the oro-maxilo-facial area
Irina Grădinaru
Influence of cardiovascular diseases on salivary parameters
Carina Balcoș
Chemopreventive effects of two antioxidants, the grape seed
extract burgund mare and curcumin, on oral carcinogenesis
Ioana Scrobotă
Signaling pathways involved in chemoprevention with
biomaterials based on silver nanoparticles in oral dysplastic
keratinocytes
Adriana Filip
17.30 – 18.30
Ambasador Room
Worwag Symposium
Simona Clichici, Petru A. Mircea
18.30-19.15 Poster Session 2 (Posters 11 – 25)
Chairmen: Raluca Papacocea, Cătălin Bogdan, Marcel Perian
20.00 Gala Dinner
Bricks Restaurant
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
8
SÂMBĂTĂ, 29 SEPTEMBRIE 2018
Conference session
09.00 – 10.30
Sala Forum
Session 6: Young physiologists symposium
Chairmen: Carmen Tatu, Daniela Mitrea, Cătălin Bogdan
Study of PDT antiangiogenic effect in melanoma-endothelial
cells co-cultures
Teacoe Ioana
Curing Ambrosia allergy one step at a time. An insight into
Amb a 6 allergen expression
Robert Gal
Effects of acute and subacute hypobaric hypoxia on oxidative
stress biomarkers: a study on the Alps
Luca di Natale
Nanotechnology for Improvement of Human Dental Follicle
derived Stem Cells Differentiation into Retinal Progenitors
Adrian Soritau
Thymus plant extract improves glucose levels and reduces
oxidative stress in experimental diabetes mellitus
Mitre Andrei
Antioxidative and Antidiabetic Effects of Thiazolidinediones in
Streptozotocin-Induced Diabetes type 1
Bolunduț Dinu
Intervention of Spironolactone in the oxidative and
inflammatory processes in the periovarian adipose tissue of the
PCOS-induced rats
Danusia Pușcaș
The detrimental effects of silver nanoparticles functionalizes
with Cornus Mas L. Extract on the rat testicle
Răzvan Opriș
A new approach in the treatment of experimental cholestasis
using silymarin cated nanoparticles
Roxana Cimponeriu
09.00 – 10.30
Ambasador Room
SESSION 7: Biocompatible natural and synthetic compounds with
biomedical applications
Chairmen: Luminiţa David, Annamaria Pallag, Olga Soritau
Anti-inflammatory activity of some novel phytosynthesized
flavonoid bioconjugated noble metal nanoparticles
Luminita David
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
9
Co-transplantation of immunostimulatory macrophages and
mesenchymal stem cells for the regeneration of the optic nerve
in an animal model of glaucoma
Olga Soritau
Effects of equisetum arvense l. extract on endothelial vascular
cells exposed to hyperosmotic stress
Annamaria Pallag
Biodistribution and effects of a capsular hybrid formulation
natural-synthetic
Teodora Mocan
Evaluation of biocompatibility in vivo of two antifungal agents
derived from ketoconazole
Ioana Baldea
Effects of thiazolidinediones on nerve functions in experimental
diabetic peripheral neuropathy
Irina Chis
The dual role of Metformin as an adjuvant in photodynamic
therapy against melanoma
Diana Tudor
10.30 – 11.10
Poster Session 3 (26 – 35)
Chairmen : Cătălina Ciornei, Irina Chiș, Daniela Matei
11.00 - 11.30
Foaier
Pause/Coffee break
11.30 – 13.30
Sala Forum
SESSION 8: New approches in teaching and research
Chairmen: Carmen Tatu, Ileana Ion, Simona Clichici
Integrative practical session –From Physiology. Biophysics,
Physiopathology to Cardiology
Carmen Tatu
Integrity – the integral dimension of excellence in research
Maria Aluaș
An attempt to re-define traditional teaching methods in
physiology
Cezar Login
First inter-medical school physiology quiz
Nicu Andronic
13.30 – 14.00
Sala Forum
CONCLUDING REMARKS, AWARDS and
TAKE HOME MESSAGES
Chairmen: Simona Clichici, Carmen Panaitescu
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
10
POSTER SESSION
FRIDAY, 15.00-15.30
1. Propolis - The Natural Bioregulator In Diabetes And In Improving The Of The
Gonadotropic Hormones
Bacalov Iurie
2. Modifications Of Corticosteron In The Experimental Diabetes On The
Background Of The Propolis Tincture Administration
Bacalov Iurie
3. Cardiovascular Response In Sleep Deprived Subjects
Papacocea Ioana Raluca
4. Oxidative Stress Is A Key Factor In Patients With Traumatic Brain Injury
Papacocea Ioana Raluca
5. Study Of Circadian Changes Of Hemostase At Birth
Ioana Anca Bădărău
6. Chronic Administration Of [Acei] And [Arbs] May Improve Scopolamine-Induced
Memory Impairment In Mice
Daniela-Carmen Ababei
7. Osteoporosis, inflammation and periodontal disease
Dan Piperea-Sianu
8. Lipid Fractions That Correlate With Insulin Resistance In Newly Diagnosed Type
2 Diabetes Patients
Cosmin Vesa
9. Ecg Changes In Acute Co Poisoning
Mariana Catalina Ciornei
10. The Influence Of Body Mass Index On Retinal Vascular Caliber In Patients With
Arterial Hypertension
Alina Gabriela Dumitrescu
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
11
FRIDAY, 18.30-19.15
11. Therapeutical Potential Of Intravenous Curcumin Administration In
Experimantal Migraine
Alexandra Bulboaca
12. Is p-gp a cause of the interaction between amiodarone and furosemide?
Maria Adriana Neag
13. The Importance Of Q-T Interval Changes In Patients With Atrial Fibrillation
Irina-Anca Eremia
14. Cortical Oscillations In An Animal Model Of Dystonia Caused By Cerebellar
Dysfunction
Ioana Antoaneta Georgescu
15. The Pathophysiology Of Smooth Utero-Tubular Muscles
Roxana Mihaela Barbu
16. Renal Denervation Impact Upon The Baroreflex Control Of The Heart Rate In
The Model Of Reduced Renal Mass, Salt Sensitive Volume-Overload
Hypertension
Şerban Dragomir-Nicolae
17. Cytokines In Bronchoobstructive Airways Diseases
Ioana Corina Bocsan
18. Evaluation Of Serum Transaminases In Hypoxia
Mihai Livia Gratiela
19. Motor Behavior In Mice During Dystonia Induced By Cerebellar Kainic Acid
Application
Razvan-Alexandru Steopoaie
20. Effect Of Implanted Nanoparticles Of Polylactic Acid (Npllla) Enriched Bone
Cement On A Femoral Experimental Defect In Rats – Preliminary Results
Alexandra Iulia Blidaru
21. Possible Benefits Of Selenium Supplementation In Autoimmune Thyroiditis
Ionela-Lăcrămioara Şerban
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
12
22. Topical Application Reinforced By Low-Level Laser Therapy On An Animal
Model Of Hair Regrowth - New Zealand Rabbits
Meda Sandra Orasan
23. Success of cardiac resynchronization in a patient with ischemic cardiomyopathy.
A case report
Irina Mușa
24. Interventional therapy in mitral regurgitation as an alternative to surgical
treatment? A case report.
Andrei Meșină
25. Early Markers For Cardiovascular Damage In Patients With Pulmonary Silicosis
Before The Occurrence Of Chronic Pulmonary Heart
Georgică Târtea
Saturday, 10.30 – 11.10
26. The Effect Of Three Different Doses Of Rhodiola Rosea, On Intense Physical-
Stress
Ramona-Niculina Jurcău
27. Effect Of Schisandra Chinensis On Heart Rate, Glycemia And Malondialdehyde,
In Exercise-Stress
Ramona-Niculina Jurcău
28. Influence Of Astragalus Versus Placebo, On Anxiety And Glycemia In
Psychological-Mental Stress
Ramona-Niculina Jurcău
29. Exploration Scintigraphy In Parathyroid Pathology
Carmen Angela Sfrangeu
30. When Nature Does Not Help Physiology – The Use Of Recombinant Allergens
For The Study Of The Allergic Immune Response
Laura Marusciac
31. Experimental Orthodontic Bracket Bonding Material Testing
Anca Mesaros
32. In Silico Insight Into Epigenetic And Transcription Chemopreventive Signaling
Mechanism In Oral Cancer
Ramona Suharoschi
ROMANIAN SOCIETY OF PHYSIOLOGY
The 30th Conference of physiology:
”Integrative physiology – From fundamental mechanisms to biomedical application”
27th to 29th of September 2018
Cluj-Napoca, Grand Hotel Napoca
13
33. Clinical And Hematological Evaluation Of The Nutraceutical Effects Of 3 Types
Of Eco-Zonar (Lactoserum Zonar With Extract Of Zingiber Officinale And
Honey) On Healthy Wistar Rats
Marcus Ioan
34. Treatment Of Ligature-Induced Periodontitis In Rats With Natural Revealers And
Photodynamic Therapy
Laura Monica Rusu
35. Biocompatibility Evaluation Of The Experimental Dental Composites
Codruta Sarosi
36. Biochemical modifications during pregnancy of patients with miscarriages
Antoaneta Punga
37. Fetal cystic hygromas in first trimester
Antoaneta Punga
38. Management of tubal ectopic pregnancy
Antoaneta Punga