Sampling Equipment

Traditional Sampling Issues

• Inefficient sampling procedures can incur unnecessary costs• Product wastage (more sample media taken out than

needed)• Purchase of special equipment and clothing for

operator safety• Inefficient sampling procedures can present

health and safety hazards• Environmentally unfriendly• Risk of operator exposure

Representative Sampling

• Main objectives• Obtain true representation of product• Collect sample with no contamination to sample or process

• Benefits • Reduction/Prevention of uncontrolled spillages and pollution

from the sampling process (due to controlled sample volume)• Protection of operator from hot, corrosive, or toxic chemicals

without the need for PPE (personal protective equipment)• Sample media cost savings from ability to sample specific

volume of product (especially in the case of high value pharmaceuticals, fine metals, etc.)

DDPS Sampling

• Range of solutions available based on level of containment required• From simple, manual units to remote, automated

systems• Analysis systems

• Options available for toxic, flammable and corrosive media• Systems with all wetted parts• Various corrosion-resistant materials of construction

(PFA, Hastelloy, etc.)

DDPS Sampling

• Range of solutions available based on level of containment required• From simple, manual units to remote, automated

systems• Analysis systems

• Options available for toxic, flammable and corrosive media• Systems with all wetted parts• Various corrosion-resistant materials of construction

(PFA, Hastelloy, etc.)

Some industries who utilize sampling for quality control:• Pharmaceutical• Chemical• Biotechnology• Food and

Beverage• Petrochemical

Inline Samplers

Enables representative sampling direct from process pipeline– Good option when obtaining a

sample from a vessel is too difficult.– Ideal for taking a sample between

process steps.– Alternatively, can be used to monitor

quality of incoming chemicals or manufactured product.

Surface Mounted Samplers

Representative samples can be taken from large pipelines or from the sidewall of vessels.

Samples can be collected when the vessel is under complete vacuum or when the product is too viscous to use normal dip tube sampling operations.

Vessel Mounted Samplers

– Single - Sample is drawn from vessel up dip pipe using site vacuum.

– Recirculating - Diaphragm pump creates vacuum to draw sample up dip pipe and then recirculates it through the system.

– Compact Recirculating – engineered for plant areas with minimal space.

Three main types of vessel mounted samplers:

Recirculation Sampling System

Vessel mounted recirculating sampler features the following options– Permanent or mobile mounting– PFA/PTFE or Hastelloy C wetted

surfaces– Dosing– pH– Temperature

Recirculation Sampling Sequence

Draw sample into enclosed container

Start with Clean System

Start pump to circulate process fluid

Recirculation Sampling Sequence (cont’d)

Wash/Flush inlet loop

Wash/Flush outlet loop

N2 blowdown/ Dry outlet loop

N2 blowdown/ Dry inlet loop

Sampling System Options

Alternative MOCs Safety cabinet High temperature designs Sample treatment (heating or

cooling) Various connection types Automation

Sampling System Options Sample dispensing standard options

include:– Hand held bottle - Simple solution for non-

toxic products

– Threaded bottle connector - Most common option, features integral vent

– Septum-capped bottle assembly - Cap seals bottle from atmosphere and needle assembly punctures holes in septum for filling and venting

– Syringe - No bottle is used; instead the sample is drawn directly from the process and contained within a borosilicate glass tube within the syringe assembly.

Additional Resources– Sampling Equipment Webpage– Sampling System Questionnaire– Contact Us– Call 908.317.2585 to speak with a DDPS

representative

Thank you