SALT KILLS

The Mission

Coronary Artery Disease In Indians in USA ( CADI)

PUBLIC ENEMY # ONE

High blood pressureStrokeHeart diseaseObesityOsteoporosisAsthmaStomach cancerAnd of course, dementia 56 million Americans Affected

Salt and hypertension In 1952, Brookhaven's Lewis Dahl began his pioneering work connecting salt and hypertension. During 25 years of tests, he discovered that high salt intake was more dangerous in youth, and recommended that no salt should be added to baby foods. He also showed that a person's genetic background greatly affects their susceptibility to hypertension from salt.

Lewis K. Dahl

Salt Intake

B P

INTERSALT

AGE

BP

90/60

Yanomami Indians Range of BP and impact of age on BP

Jeremiah Stamler Father of Preventive Cardiology

“The INTERSALT study results, which agree with the findings from other

diverse studies, including data from clinical observations, therapeutic interventions, randomized controlled trial, animal experimentation, physiologic investigations, evolutionary biology research, anthropology research, and epidemiologic studies,

support the judgment that habitual high salt intake is one of the quantitatively important, preventable mass exposures causing the unfavorable population wide blood pressure pattern that is a major risk factor for epidemic cardiovascular disease.“……

…………….Stamler

“Ignoring the overwhelming scientific consensus on this issue…[is] supportive of positions adapted by special interests and comes at the expense of public health”.

Limit salt intake to 1500 mg a day

Institute of Medicine

STUDIES SUPPORT POPULATION BASED EFFORTS TO LOWER EXCESSIVE DIETARY SODIUM INTAKE

EVIDENCE SUPPORTS A POSITIVE RELATIONSHIP BETWEEN HIGHER LEVELS OF SODIUM INTAKE AND RISK OF HEART DISEASE, IS CONSISTENT WIH PREVIOUS RESEARCH BASED ON SODIUM EFFECTS ON BLOOD PRESSURE

MAY 14, 2013

1 MILLION people studied

Systolic Blood Pressure andRelative Cardiovascular Mortality Risk

Cardiovascular mortality doubles for each 20 mmHg increase in blood pressure

Systolic Blood Pressure115 135 155 175

Relative risk of cardiovascular mortality at prehypertension (systolic blood pressure of 140 mmHg)

• One billion People with High blood pressure…..WHO• Nine out Ten People do not Follow salt reduction…CDC• Salt Content of Processed food unchanged…Multiple Sources

Cardiac Hypertrophy From Fighting Hypertension

Mitral Regurg From Hypertensive Cardiomyopathy

High blood pressure Cholesterol

build up in the arteries

Heart muscle overgrowth

Heart attacks Loss of

heart muscle

Diastolic dysfunction

Systolic dysfunction

Heart Failure

Both

SALT

Diastolic DysfunctionLessons From ADHERE

(Acute Decompensated Heart Failure Registry)

• Over 5 Million Americans living with Heart Failure

• 250,000 Deaths per year• 500,000 new cases per year• 33% die within the first diagnosis• Systolic function preserved in nearly half the

patients• Number One Reason for Hospitalization

OSTEOPOROSIS FRACTURE

Greater than combined risk of Breast and Ovarian Cancers

Prostate cancer(1 in 3 women and 1in 5 men)

STROKE

Mechanisms of Dementia

High blood pressure Increases the risk of memory loss by

600%

Auto-Immune Disease

If you incrementally increase salt, you get generation after generation

of these TH17 cells….Vijay Kucheroo

The Real Public Enemy #1

WWW.SALTKILLS.COM

SALT KILLS

The Mission