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Page 1: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP
Page 2: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP
Page 3: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP
Page 4: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP
Page 5: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP

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Page 6: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP

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Proline

Page 7: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP

Pavlov M Y et al. PNAS 2009;106:50-54

Phenylalanine

N-Me-Phenylalanine

Page 8: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP

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Page 9: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP
Page 10: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP
Page 11: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP

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Page 12: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP

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Page 13: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP

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Page 14: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP

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Page 15: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP

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Page 16: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP
Page 17: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP

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Page 18: s3-us-west-2.amazonaws.com · GTP hydrolysis Initial binding EF-Tu conf. change Codon recognition Accommodation GTPase activation Peptidyl transfer Dissociation of EF-Tu.GDP

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