888 San Clemente Drive Newport Beach CA 92660 800 678-9147 www.roth.com Member SIPC / FINRA• • • •

HEALTHCARE TRACK

By invitation only.

Please email or contact your ROTH representative at 800.933.6830.registration@roth.com

Please join ROTH for its annual three day conference, held March 13-16, 2016; one of the largest of its kind. The ROTH conference brings together executives from hundreds of growth companies and is designed to provide investors with a unique opportunity to gain insight into small and mid-cap growth companies across a variety of

sectors, including: Business Services, Cleantech & Industrial Growth, Consumer, Healthcare, Oil & Gas, Resources, Semiconductors & IT Hardware, Solar, Software and Technology.

We combine company presentations, Q&A sessions, expert panels and management one-on-one meetings to provide our institutional clients with extensive interaction with senior management.

ROTH is pleased to announce a special keynote presentation with J. Craig Venter, Ph.D. held Sunday, March 13 . Dr. Venter is regarded as one of the leading scientists of the 21st century for his invaluable contributions to genomic research. He led the private company effort during the historic quest to sequence the first draft human genome. He and the government project announced their version of the first genome at the White House in 2000.

Keynote: Date: Sunday, March 13, 2016Time: 3:15pm - 4:15pmWhere: Pacific Promenade Ballroom, Ritz-Carlton, Laguna Niguel

ROTH Healthcare Analysts Scott Henry, CFA, Joe Pantginis, Ph.D., Michael Higgins, Elemer Piros, Ph.D, and

Chris Lewis are pleased to feature presentation tracks, during the conference, dedicated to:

These tracks will include presentations from over 150 private & public companies in key sub-sectors: including

BioPharmaceuticals, Biotechnology, Medical Technology and Speciality Pharmaceuticals.

“Exploring the Human Genome with J. Craig Venter, Ph.D.”

HEALTHCARE

TRACK SPONSORS

KEYNOTE SPONSOR

PRESENTING COMPANIES

HEALTHCARE TRACK

22nd Century Group, Inc. (XXII) Curis, Inc. (CRIS) Ohr Pharmaceutical, Inc. (OHRP)Abeona Therapeutics, Inc. (ABEO) Cutera, Inc. (CUTR) Onciomed, Inc. (PRIVATE)AcelRx Pharmaceuticals, Inc. (ACRX) CymaBay Pharmaceuticals (CBAY) OncoSec Medical Incorporated (ONCS)Actinium Pharmaceuticals, Inc. (ATNM) CytoKinetics, Inc. (CYTK) Orthocell Ltd. (OCC)Acura Pharmaceuticals (ACUR) Cytori Therapeutics, Inc. (CYTX) Otic Pharma, Inc. (PRIVATE)Aduro Biotech, Inc. (ADRO) Del Mar Pharmaceuticals Inc. (OTCQX:DMPI) Paion AG (FWB:PA8)Advantagene, Inc. (PRIVATE) Delcath Systems, Inc. (DCTH) Palatin Technologies, Inc. (PTN)Advaxis Inc. (ADXS) Depomed, Inc. (DEPO) Peregrine Pharmaceuticals, Inc. (PPHM)Aethlon Medical, Inc. (AEMD) Derma Sciences, Inc. (DSCI) Pharming Group NV (AEX:PHARM)Agile Therapeutics, Inc. (AGRX) Digirad (DRAD) Pieris Pharmaceuticals, Inc. (PIRS)AirXpanders (AXP) Dimension Therapeutics, Inc. (DMTX) Pixium Vision (PIX)Alcobra Pharma Ltd. (ADHD) Endra Life Sciences, Inc. (PRIVATE) Poxel Pharma (POXEL)Align Technology, Inc. (ALGN) EnteroMedics, Inc. (ETRM) Progenics Pharmaceuticals, Inc. (PGNX)Altimmune, Inc. (PRIVATE) EpiEP (PRIVATE) Protagonist (PRIVATE)American Caresource Holdings, Inc. (GNOW) ESSA Pharma Inc. (EPIX) Recro Pharma, Inc. (REPH)AmpliPhi Biosciences Corporation (APHB) Evotec AG (FWB:EVTG) RedHill Biopharma Ltd (RDHL)ANI Pharmaceuticals, Inc. (ANIP) Exact Sciences Corporation (EXAS) Relmada Therapeutics, Inc. (OTCQB:RLMD)Applied Genetic Technologies Corp. (AGTC) Fate Therapeutics, Inc. (FATE) Rennova Health, Inc. (RNVA)Apricus Biosciences, Inc. (APRI) Fibrocell Science, Inc. (FCSC) RespireRx Pharmaceuticals Inc. (OTCQB:RSPI)Aptose Biosciences Inc. (APTO) Flamel Technologies SA (FLML) Resverlogix Corp. (TSX:RVX)Arbutus Biopharma (ABUS) Foamix Pharmaceuticals Ltd. (FOMX) Ritter Pharmaceuticals (RTTR)Arch Therapeutics, Inc. (OTCQB:ARTH) Foundation Health Care (OTCQB:FDNH) ROTH Capital PartnersArgos Therapeutics, Inc. (ARGS) Galectin Therapeutics (GALT) Second Sight Medical Products, Inc. (EYES)Ativa Medical (PRIVATE) Galena Biopharma, Inc. (GALE) Senestech (PRIVATE)Authentidate Holding Corp. (OTCQB:ADAT) Galmed Pharmaceuticals Ltd. (GLMD) Skylit Medical (PRIVATE)Avelas Biosciences, Inc. (PRIVATE) Glaukos Corp. (GKOS) Soft Health Technologies LLC (PRIVATE)Aveo Oncology (AVEO) Great Basin Scientific (GBSN) Sophiris Bio, Inc. (SPHS)AxoGen, Inc. (AXGN) Heart Test Labs (PRIVATE) Sorrento Therapeutics, Inc. (SRNE)Bio-Path Holdings Inc. (BPTH) Helocyte (PRIVATE) Spark Therapeutics, Inc. (ONCE)BioAmber, Inc. (BIOA) iCad, Inc. (ICAD) Stellar Biotechnologies, Inc. (SBOT)BioBlast Pharma Ltd. (ORPN) ICU Medical, Inc. (ICUI) Stemline Therapeutics, Inc. (STML)Biocept, Inc. (BIOC) Idera Pharmaceuticals, Inc. (IDRA) Strongbridge Biopharma PLC (SBBP)BioDelivery Sciences International, Inc. (BDSI) Immune Pharmaceuticals, Inc. (IMNP) Sucampo Pharmaceuticals, Inc. (SCMP)BioLife Solutions, Inc. (BLFS) ImmunoCellular Therapeutics, Ltd. (IMUC) Synergy Pharmaceuticals, Inc. (SGYP)BioLineRx Ltd. (BLRX) Implanet (EPA:IMPL) Synthetic Biologics Inc. (SYN)Biomerica Inc. (OTCQB:BMRA) Imprimis Pharmaceuticals, Inc. (IMMY) TapImmune, Inc. (OTCQX:TPIV)BiondVax Pharmaceuticals, Ltd. (BVXV) Ionis Pharmaceuticals (IONS) TearLab Corporation (TEAR)Bionik Laboratories Corp. (OTCQB:BNKL) IRadimed Corporation (IRMD) Teligent, Inc. (TLGT)Bionomics Ltd. (ASX:BNO) Juniper Pharmaceuticals (JNP) Tetraphase Pharmaceuticals, Inc. (TTPH)BioSig Technologies (OTCQB:BSGM) Kardium (PRIVATE) TG Therapeutics, Inc. (TGTX)BioSpecifics Technologies Corp. (BSTC) Lannett Company, Inc. (LCI) Titan Pharmaceuticals, Inc. (TTNP)Biota Pharmaceuticals, Inc. (BOTA) LeMaitre Vascular, Inc. (LMAT) Tobira Therapeutics, Inc. (TBRA)BioTelemetry, Inc. (BEAT) Ligand Pharmaceuticals, Inc. (LGND) Tracon Pharmaceuticals, Inc. (TCON)bluebird bio, Inc. (BLUE) Lipocine, Inc. (LPCN) Trevena Inc. (TRVN)Cancer Genetics, Inc. (CGIX) MabVax Therapeutics Holdings, Inc. (OTCQB:MBVX) Trinity Biotech plc (TRIB)CareDx, Inc (CDNA) Masimo Corporation (MASI) TSO3 (TSX:TOS)CAS Medical Systems, Inc. (CASM) Mast Therapeutics (MSTX) UroGen Pharma (PRIVATE)Catalyst Pharmaceuticals, Inc. (CPRX) Matinas BioPharma Holdings, Inc. (OTCQB:MTNB) Vaccinex (PRIVATE)Cellectar Biosciences, Inc. (CLRB) Medigus, Ltd (MDGS) Vascular Biogenics Ltd. (VBLT)Cerenis Therapeutics Holdings SA (CEREN) Mico Innovations (PRIVATE) VBI Vaccines, Inc. (VBIV)Cerulean Pharma, Inc. (CERU) Mustang Bio Inc. (PRIVATE) Verastem, Inc. (VSTM)Champions Oncology, Inc. (CSBR) Naia Rare Diseases, Inc. (PRIVATE) Vericel Corporation (VCEL)Check Cap Ltd (CHEK) Nanobiotix (NANO) Vical, Inc. (VICL)Checkpoint Therapeutics, Inc. (PRIVATE) Natus Medical, Inc. (BABY) ViewRay (OTCQB:VRAY)Cipher Pharmaceuticals, Inc. (CPHR) Nektar Therapeutics (NKTR) Viveve Medical, Inc. (OTCQB:VIVMF)Cocrystal Pharma, Inc. (OTCQB:COCP) Nemus Bioscience, Inc. (OTCQB:NMUS) vTv Therapeutics, Inc. (VTVT)Cogentix Medical, Inc. (CGNT) NeoGenomics Laboratories, Inc. (NEO) ZELTIQ Aesthetics Inc (ZLTQ)CombiMatrix Corporation (CBMX) Neuralstem, Inc. (CUR) Zosano Pharma Corporation (ZSAN)Conatus Pharmaceuticals, Inc. (CNAT) Neuroderm Ltd (NDRM) Zynerba Pharmaceuticals, Inc. (ZYNE)Concert Pharmaceuticals, Inc. (CNCE) Nivalis Therapeutics, Inc. (NVLS)ContraFect Corporation (CFRX) NovaBay Pharmaceuticals, Inc. (NBY) Additional companies to be confirmedCorMedix, Inc. (CRMD) Oculus Innovative Science (OCLS) Subject to change | as of 3/11/16

888 San Clemente Drive Newport Beach CA 92660 800 678-9147 www.roth.com Member SIPC / FINRA• • • •

This is not an offer or solicitation of the securities herein.