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Nigeria Centre for Disease Control Protecting the health of Nigerians Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe Ihekweazu Director General Lassa fever: The Nigerian Experience

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Page 1: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

Nigeria Centre for Disease ControlProtecting the health of Nigerians

Role of NPHIs in Re-Emerging Infectious Diseases

Dr. Chikwe Ihekweazu

Director General

Lassa fever: The Nigerian Experience

Page 2: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL2

Mandatory disclosure slide

No conflict of interest

Page 3: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL3 3

Population ~ 186 million

Annual population growth rate of 2.6%

Recent outbreaks - Lassa fever, Ebola, Monkeypox, Yellow fever, Meningitis

Low expenditure on health as a percentage of GDP

Multiple competing priorities for Government

Nigeria’s health and economy

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NIGERIA CENTRE FOR DISEASE CONTROL4

Major outbreaks in Nigeria

Page 5: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL5

Lassa fever in Nigeria

Large outbreak in 2018

638 confirmed cases

171 deaths

23/36 states affected

Case fatality: 26%

Cases concentrated in three hotspot

states

Ongoing outbreak in 2019

420 confirmed cases

93 deaths

21/36 states affected

Case fatality: 22%

Cases being detected in new states

Page 6: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL6

Trends of Lassa fever in Nigeria(2016-2019)

Page 7: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL7

Page 8: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL8

Improved digital surveillance

State/Regional Health Department

Nigeria Centre for Disease Control

District / Local Government Area Health Dpt.

Local Health Care Facilities

WHO, ECOWAS, R-CDC

CDC

Aggregated weekly

(by Monday)

Aggregated weekly

(by Tuesday)

Aggregated monthly

Aggregated weekly

(by Wednesday)

Page 9: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL9

Improved digital surveillance

Field

investigator

Field

investigator

Laboratory

State/Regional Health Department

Nigeria Centre for Disease Control

District / Local Government Area Health Dpt.

Local Health Care Facilities

weekly

WHO, ECOWAS, R-CDC

IDSR

001A

manual

data entry

CDC

Field

investigator

Aggregated weekly

(by Monday)

Aggregated weekly

(by Tuesday)

Aggregated monthly

Aggregated weekly

(by Wednesday)

Page 10: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL10

Cases in ‘new states’20192018

LEGEND

≥1 Suspected Cases

1- 50 Confirmed Cases

>50 Confirmed Cases

1 dot = 1 Confirmed Case

Page 11: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL11

Improved diagnostics- Four new molecular laboratories

Page 12: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL12

Improved logistics system

Page 13: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL13

Increasing use of EOCs

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NIGERIA CENTRE FOR DISEASE CONTROL14

National sample transport system

Page 15: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL15

Improved almost real-time sequencing in Nigeria

Page 16: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL16

Research activities

• National Lassa fever research plan

developed

• Research as core pillar of EOC

• National Lassa Fever Research

Consortium

• Lassa fever- critical areas for WHO R&D,

CEPI vaccines

Page 17: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL17

Improved collaborationPANDORA-ID NET SUPPORT

Page 18: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL18

2019 Lassa fever preparedness

• Training of 1,000 health workers in Nigeria on Lassa fever management,

diagnosis and surveillance

• Prepositioning of treatment and diagnostic supplies to the 21 states that

recorded cases in 2018

• Publication of Lassa fever messages in newspapers, weekly radio shows,

and intensive community engagement

• High level advocacy visits to State Governments

• Review of case management guidelines, initiated a Lassa fever Research

Consortium and hosted International Conference on Lassa Fever

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NIGERIA CENTRE FOR DISEASE CONTROL19

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NIGERIA CENTRE FOR DISEASE CONTROL20

Mandate

Prevent, detect, and control spread of communicable diseases

Coordinate surveillance systems to collect, analyse and interpret data on communicable diseases to guide action

Support States in responding to small outbreaks, and lead response to large disease outbreaks

Develop and maintain a network of public health laboratories

Conduct, collate, synthesise and disseminate public health research to inform policy

Coordinate the compliance with international health regulations

Nigeria Centre for Disease Control

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NIGERIA CENTRE FOR DISEASE CONTROL21

NCDC’s role in infectious diseases(Lassa fever)

• Coordination of public health surveillance,

laboratory and response functions

• Coordination of partners’ support

• Building trust among Nigerians through

regular communication

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NIGERIA CENTRE FOR DISEASE CONTROL22

Why we need strong NPHIs

1. A public health event can go from local to global very rapidly

2. Global health security can only be assured by local health protection

3. A strong surveillance & response system, managed by a skilled public

health workforce, organised in a national public health institute is needed in

every country

4. Partnerships matter more than ever before, NPHIs coordinate these

5. Vulnerability for one is vulnerability for all

Page 23: Role of NPHIs in Re-Emerging Infectious Diseasesregist2.virology-education.com/presentations/2019/2ICREID/09_Ihek… · Role of NPHIs in Re-Emerging Infectious Diseases Dr. Chikwe

NIGERIA CENTRE FOR DISEASE CONTROL23

Our posters at ICREID 2019

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NIGERIA CENTRE FOR DISEASE CONTROL24

THANK YOUEmail: [email protected]