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Roe Bio-Medical Products www.roebiomed.com (631) 236-9155 Fax (631) 289-4126 125 Wilbur Pl. Bohemia, NY 11716 A) ROE VACUUM BEDDING SYSTEMS - VBS INTRODUCTION – pg 2 THEORY of OPERATION- SEPARATING VALVE - pg 3 TECHNOLOGICAL ENHANCEMENTS - pg 4 B) VACUUM BEDDING REMOVAL SYSTEMS VACUUM BEDDING REMOVAL SYSTEM- VBRS 9400 - pgs 5-9 DUMP STATIONS- SCD 6800 - pgs 10-12 AUTOMATED DUMP STATIONS – ADS 6900 - pg 13 AUTOMATED BAGGING SYSTEMS- VBRB 7000 - pg 14 MULTI-PORT SYSTEMS MPVBRS - pgs 15-16 FAQ’s - pg 17 HELPFUL PLANNING HINTS - pg 18 C) VACUUM BEDDING DELIVERY SYSTEMS AUTOMATED BEDDING DISPENSER – VBDS 4900 – pgs 19-20 VACUUM BEDDING SUPPLY SYSTEMS- VBSS 1000, BBDS – pgs 21-23 VACUUM BEDDING TRANSFER SYSTEMS – VBTS 9000 – pgs 24-26 CLEAN BEDDING PACKAGING SYSTEMS – VBPS 7000 pg 27 BEDDING DISPENSERS VBDS 3000 pg 28 CAGE INVERTERS CIS 6000 – pg 29 D) RESOURCE SECTION pg 30 CONTINUOUS IMPROVEMENT PROGRAM – pg 31 OHS ALLERGIES IN THE LABORATORY ANIMAL FACILITY – pgs 32-33 New or Novel Products that Reduce Labor, Cost, and Injury - pgs 34-39 LAB ANIMAL, January 1999, 28(1): 48 HOW IT WORKS – pg 40 SPARE PARTS LIST – pg 41 L.A.R. FACTORS – pg 42 QUICK METHOD FOR CALCULATING PROCESS TIMES & COSTS – pg 43 TIME MOTION STUDIES (EXAMPLE) – pg 44 VBS UTILITY REQUIREMENTS – pg 45 VOLUME & WEIGHT CONVERSIONS – pg 46 CUSTOMER LIST – pg 47-48 1 5/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

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Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

A) ROE VACUUM BEDDING SYSTEMS - VBS

INTRODUCTION – pg 2

THEORY of OPERATION- SEPARATING VALVE - pg 3

TECHNOLOGICAL ENHANCEMENTS - pg 4

B) VACUUM BEDDING REMOVAL SYSTEMS

VACUUM BEDDING REMOVAL SYSTEM- VBRS 9400 - pgs 5-9

DUMP STATIONS- SCD 6800 - pgs 10-12

AUTOMATED DUMP STATIONS – ADS 6900 - pg 13

AUTOMATED BAGGING SYSTEMS- VBRB 7000 - pg 14

MULTI-PORT SYSTEMS – MPVBRS - pgs 15-16

FAQ’s - pg 17

HELPFUL PLANNING HINTS - pg 18

C) VACUUM BEDDING DELIVERY SYSTEMS

AUTOMATED BEDDING DISPENSER – VBDS 4900 – pgs 19-20

VACUUM BEDDING SUPPLY SYSTEMS- VBSS 1000, BBDS – pgs 21-23

VACUUM BEDDING TRANSFER SYSTEMS – VBTS 9000 – pgs 24-26

CLEAN BEDDING PACKAGING SYSTEMS – VBPS 7000 – pg 27

BEDDING DISPENSERS VBDS 3000 – pg 28

CAGE INVERTERS CIS 6000 – pg 29

D) RESOURCE SECTION – pg 30

CONTINUOUS IMPROVEMENT PROGRAM – pg 31

OHS ALLERGIES IN THE LABORATORY ANIMAL FACILITY – pgs 32-33

New or Novel Products that Reduce Labor, Cost, and Injury - pgs 34-39 LAB ANIMAL, January 1999, 28(1): 48

HOW IT WORKS – pg 40 SPARE PARTS LIST – pg 41

L.A.R. FACTORS – pg 42

QUICK METHOD FOR CALCULATING PROCESS TIMES & COSTS – pg 43

TIME MOTION STUDIES (EXAMPLE) – pg 44

VBS UTILITY REQUIREMENTS – pg 45

VOLUME & WEIGHT CONVERSIONS – pg 46

CUSTOMER LIST – pg 47-48

15/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

Please take a moment to review the enclosed material on handling laboratory animal bedding. The VBDS 4900 Vacuum Bedding Delivery System combines an automated Bag slitter with silo, or bulk bag system with a dispenser head and cage inverter. The VBDS 4900 is compatible with standard bedding bags or bails from 15-100 lbs. Paper/Wood pulp, chip or shavings, cob etc. The bedding only needs to be handled by the operator one single time. The VBRS Vacuum Bedding Removal System has been specifically developed and extensively field-tested to handle dry, wet or slurry animal bedding materials quickly and ergonomically. 1,2, 3 This system automatically transports materials to compactors, dumpsters, incinerators, or tilt carts, over extended distances. 6, 7 The VBRS Vacuum Bedding Removal System eliminates dust, aerosols, allergens, and hazardous materials. As a stand alone system (wand only) or connected to a dump station, the VBRS is an efficient and effective means to remove soiled bedding. Cost effective and priced to pay for itself. Proven to pay for itself through labor savings, improved productivity and reduced material handling. 4, 5 High-load performance exceeds the throughput capacity of all popular conveyor wash equipment. 6, 7 Compact size. Easy to install and maintain. Does not require sealed dumpsters, water, drains, utility areas or other special facility design considerations or alterations. For additional Information, time motion studies or to arrange for a site visit, call (877)243-0674 or email us at [email protected]. Sincerely, Philippe Roe President __________________ 1) R. Thurston E. Georgelos, J. Fusco. 1997. Developing A Self-Directed Ergonomic Team. Workshop W-5. AALAS 48th National

Meeting 2) E. Georgelos, M. Broggi, R. Thurston, T. Corsi, R. Belenchia, M. Generess, T. Garrison, C. Matherne. 1997. Task Evaluation

and Solution Development for Ergonomic-Related Injuries at a Research Animal Facility. Contemp. Top. Lab. An. Sci., 36(4):68 3) E. Georgelos. 1998. Ergonomics, What Is It and How Can I Get Some? SNEAALAS Meeting, Feb. 10, 1998. 4) Roe Bio-Medical Products, Inc. 1994. Time/Motion Study. On file. 5) Roe Bio-Medical Products, Inc. 1997. Time/Motion Study. On file. 6) Giannotti Associates. 1994. Design Performance & Feasibility Study. On file. 7) Giannotti Associates, Roe Bio-Medical Products, Inc. 1997. Client Application Feasibility Study. On file.

25/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

HIGH EFFICIENCY SEPARATING VALVE

The high efficiency Separating Valve is the basis of the vacuum conveying systems in the Vacuum Bedding Removal Systems VBRS, Vacuum Bedding Delivery Systems VBDS, and Vacuum Bedding Transfer System VBTS. BRIEF DESCRIPTION: The patented high efficiency Separating Valve has been designed and sized specifically for the variety of materials and conditions found in laboratory animal facilities. The Separating Valve represents a departure from traditional vacuum conveying systems that were designed for handling relatively uniform, free flowing materials and eliminates the necessity for large blowers, large cyclone separators, large dust collectors, special sealed dumpsters and costly utility rooms.

The Discharge Unit, containing the Separating Valve, shares the footprint of the receptacle (compactor, dumpster, bin or hopper) with no addition space requirements. A high performance regenerative vacuum/blower is housed in the Discharge Unit.

THEORY OF OPERATION: Animal bedding (sterile, soiled or wet material, including feed) is vacuumed out of the cages, Automatic Dump stations, Bulk Bag Discharges, or hoppers. The material is transported via the Transport tube (1) to the Separating Valve and collected in chambers (3) of the Separating Valve. Each chamber, in the Separating Valve, contains a coarse filtration screen (4), which separates the vacuum air (2) from the material being collected. The chambers (3) in the Separating Valve, alternate between vacuum-intake (6) portion of the Separating Valve and the ambient pressure-discharge (5) portion of the Separating Valve. As the chambers rotate to the discharge portion of the assembly, the material leaves the chambers, descending into the receptacle (compactor, dumpster, bin or hopper) via the Discharge Tube. After the coarse filtration screen, the vacuum air (2) passes through a Cyclone Separator to remove the dust and fines. The air is then filtered by first passing through a Filtration Collection Bag and then through a HEPA filter. The filtered air is then pulled through the Regenerative Vacuum/Blower and exhausted through the Discharge.

35/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

Touch Panel Interface Programmable Logic Controls PLC

Roe Bio-Medical Products systems, feature Graphic Touch Panel Interface, at each end point (Bedding Dispensers and Bedding Bin Discharges; and Vacuum Waste System work stations and automated bag filler/sealer) with PLC’s having built in communication and data management capabilities. The readily comprehensive Graphic Touch Panel Interface depicts the status and operation of the system throughout the facility. The self-diagnostic feature monitors the parameters under normal operating conditions and signal operator alerts (such as: change filters, low bedding supply, bin full, etc.). When system interruptions occur, the graphic touch panel guides the operator where and how to resolve the issues. As a management tool, the system provides a means to track activities, throughputs, cage counts, etc. Data is imported onto spreadsheets or may be incorporated into other facility data acquisition systems. Multiple/interactive applications are transferred throughout the facility, using an off-the-shelf LAN/WAN operating system. Connection to remote nodes via modem lines for factory support, system adjustments, operation analysis and management control. The remote communication capability permits management to retrieve operating data or for the factory to assess operation conditions.

Rugged design for NEMA 4X applications such as: wash down areas, and 0 - 50C environments.

Features: Designed and manufactured for reliability. 24 years experience in major pharmaceutical plants. Feature-rich with Interact Panel Tools, Graphics, Alarming & Networking Modules. Self-Diagnostic graphics for condition analysis, which allows the operator a quick view

of the systems status. 6” graphic touch screen displays. Multiple control device connectivity. Quick and easy clip mounting in a NEMA 4X enclosure. Electrical Requirements: 120V at the Touch Panel site.

GRAPHIC TOUCH PANNEL Easy-to-use and understand graphics

Operator friendly Monitoring graphics create an intuitive

Human Machine Interface for operators, maintenance and support personnel.

45/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

55/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

FREES SPACE – SHARES THE FOOT PRINT OF ANY NON-DEDICATED / GENERAL PURPOSE COMPACTOR NO MECHANICAL / UTILITIES ROOM REQUIREMENTS SIMPLER DESIGN – SYSTEM MANUFACTURED AS A SINGLE UNIT

IDEAL FOR NEW CONSTRUCTION OR RETROFIT

65/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

VACUUM BEDDING REMOVAL SYSTEM – VBRS 9400 FOR REMOVING LABORATORY ANIMAL BEDDING

DESCRIPTION:

The VBRS 9400, Vacuum Bedding Removal System, transports laboratory animal waste bedding from a central cage wash area or changing station to any remote non-dedicated receptacle, compactor, dumpster or bagging equipment. The VBRS 9400 can handle the materials for well over 2000 cages per hour from soiled cages and for distances exceeding 700 feet, with 2” stainless steel transport lines.

The VBRS 9400 system is housed in an acoustical and environmentally controlled cabinet and is factory preassembled and tested on a stainless steel skid-pack. For typical installations, the VBRS 9400 skid-pack is elevated on stainless steel up-rights over and shares the foot print with a waste receptacle, such as a shared non-dedicated compactor. A graphic touch screen is located in the cage wash area and interfaces either a vacuum wand or a self-contained dump station with the VBRS 9400 skid pack.

FEATURES:

ERGONOMICALLY PROACTIVE - Reduces the risk of Musculoskeletal Disorders (MSD’s) and other injuries caused by lifting, resulting in less time off and greater productivity.

REMOVES DUST & ALLERGENS – Fully contained, vacuum air carries away the dust and allergens. The vacuum air is cleaned by multiple filtration steps, including membrane pocket filter and optional HEPA filter, leaving the work area and exhaust air uncontaminated.

POLY DENSE PHASE MATERIAL FLOW – The patented separating valve enables an uninterrupted flow of bedding to the waste receptacle, increasing the conveying efficiency. Can handle fluids and wet and dry materials.

VBRS 9400

COMPATIBILITY – The VBRS 9400 is compatible with all standard laboratory bedding materials including: paper pulp and chip, wood chip, shavings, cob and disposable enrichment materials.

ENERGY EFFICIENT – The ISO 9000 manufactured separating valve permits Poly Dense Phase conveying, requiring 1/10th the energy compared to dilute phase to move equivalent amounts of material. Fully documented by empirical tests and published data.

GRAPHIC TOUCH PANEL MICROCOMPUTER CONTROLS – Windows based program is easy to use with self-diagnostic graphics, condition analysis, alerts and cage count functions. Has optional built in communication and data management capabilities.

FLEXIBILITY IN LOCATION & NOMINAL SPACE REQUIREMENT - The Vacuum System and Transport Tubing enable the bedding to be conveyed up to 700’ and 8 floors apart without extra utility room.

EASY MAINTENANCE - The entire system can be cleaned and sterilized in place with liquid sterilants, without the need for dismantling or disruption of service. Serviceable non-proprietary parts are readily available of the shelf.

UTILITY REQUIREMENTS

208-230/480v -3 phase, 60 Hz, 20/10 AMP, 120v, 1/60/ 20 AMP Consult factory for 50 Hz and special purpose applications Compressed Air – 80 to 90 psi, 8 CFM capisity, 4 CFM comsumption

OPTIONS: o Ozone Generator eliminates dumpster odors. o Self-contained Dump Station SCD 6800 o Automated Dump station ADS 6900

Refer to specification sheets for specific details

75/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

Vacuum Bedding Removal System VBRS 9400

PRODUCT COMPARISON TABLE

Other Vacuum Bedding Disposal System Discharges into a dedicated waste container. A separate additional container must be used for general refuse. Rotary valve subject to binding with wet material, not compatible with liquids. Facility is subject to retro-contamination from out-side sources when system is not operating. Cannot be sterilized. Interfaces with waste container using a Harting type or similar connector, requiring manual connections with threaded fittings for container instrumentation.

Waste hauler driver must disconnect and reconnect container as a separate operation.

Subject to damage if not disconnected when removing waste container.

Subject to corrosion and freezing in winter. Operators are unaware of status of system function unless or until operation is disrupted. Controls are limited to operation of system. Utility space, complete with noise reducing hoods, dust collectors and ventilation is required. (144 sq.ft. minimum) >70 db @ 3’ with noise reducing hood. No odor control.

Roe Biomedical Products Vacuum Bedding Removal System Discharges waste into a Non-Dedicated compactor, tilt cart or any other multiple user waste container. Patented Separating valve handles wet, dry or liquid waste animal bedding. Patented Separating Valve is self-closing to maintain the integrity of the facility. Entire system can be sterilized in place (SIP). Interfaces with the waste container by utilizing a gravity plate for waste discharge.

Self contained sensors for container level and container in-place.

Waste hauler does not change routine. System detects the presence and status of

the waste container. Gravity plate slides automatically into

position when waste container is returned. Graphic Touch Panel Interface with embedded graphics and self-diagnostics. Makes it easy for operators to understand the status of the entire system, including when remote waste container is full or not present and when dump station is at capacity. PLC has built in communication modem and data acquisition capabilities for in-house and/or remote system management and control. The self-diagnostic feature monitors the operating parameters. A no-net utility space requirement as a result of the Discharge & Platform, with separating valve, blower, filters, etc., shares the footprint of the non-dedicated waste container. >70 db @ 2’. Odors associated with the waste are controlled with an ozone generator.

85/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

Some Considerations: Outlined below is a comparison of the steps between the Model VBRS 9400 Vacuum Bedding Removal System and macerator (under-sink) type systems to demonstrate the difference in the labor to accomplish the same task. The reduced risk of Musculoskeletal Disorders (MSDs) and other injury risk factors should also be evident.

MACERATOR WASTE DISPOSAL Pans are lifted off transport cart and moved to macerator (carefully without spilling). Pans are then tilted up and/or turned over to empty the majority of debris. Pans are then tilted back and/or turned back over and scraped. Pans are then tilted back again to remove remaining debris. Pans are moved to and loaded into wash-rack or conveyor. Maceration generates aerosols and odors and does not trap allergens.

MODEL VBRS 9400

Pans are vacuumed while on the transport cart. Debris is removed without scraping. Pans only need to be moved once to load into wash-rack or conveyor. Odors, allergens, and dust are minimized with the vacuum air.

SOME ADDITIONAL COMPARATIVE CONSIDERATIONS

MODEL VBRS 9400

Cages and pans are virtually free of debris without scrapping - wash equipment screens remain clean. Clean, dust and allergen free work environment - vacuuming does not allow aerosol particles or odors to escape. Environmentally responsible. Transports waste bedding directly to compactor, dumpster or incinerator with air.

MACERATING WASTE DISPOSERS Debris must be scraped from cages and pans – time consuming, high risk for MSDs and other injuries. Turning over cages and pans to empty them, allows dust and allergens to escape. Maceration generates aerosols and odors. Consumes 480 gallons of fresh water per hour. Waste water treatment required. Drain clogging potential. The macerator requires extensive plumbing (supply & sanitary waste lines, etc.) & permanently occupies valuable wash area space.

5/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE © 9

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

SELF CONTAINED BEDDING DUMP STATION

SCD 6800 FOR SAFELY REMOVING SOILED LABORATORY ANIMAL BEDDING

DESCRIPTION:

The SCD6800 is a compact Self-Contained Bedding Dump Station that is designed for applications with either a single dedicated vacuum bedding removal system or for multi-port vacuum bedding removal systems, having more that one pickup point on a single vacuum removal line. The SCD 6800 collects, processes (mills, mixes, and fluidizes), then meters the soiled bedding and feed into the vacuum transport line. In multi-port vacuum systems, the SCD 6800 synchroniously meters the soiled bedding mixture into vacuum transport lines for a seamless operation. FEATURES: REDUCES DUST AND ALLERGENS – The enclosed cage dump operation runs with interior negative air flow. Optional HEPA filtration hood out performs all down draft stations, for eliminating dust and particle exposure to operators.

UNINTERRUPTED MATERIAL FLOW – The feed and wet bedding clumps are milled for particle size uniformity, and mixed for consistent moisture content, allowing for higher trouble free through-puts.

MICROCOMPUTER CONTROLS – Windows based program is easy to use and understand with self-diagnostic graphics, and condition analysis.

VERSATILE - May be docked to the front of any conveyor or tunnel type wash machine.

SCD6800 OPTIONS:

HEPA filter up-draft with blower. HEPA filter hood with negative air flow also available. BSC Class II Type A and B1 (total of 72” overall assembly height with dump station). Vacuum wand and hose with switching valve assembly. Environmental Enrichment materials separator and / or shredder. Docking latch aligns and latches/de-latches dump station onto the conveyor wash (Casters required). UTILITY REQUIREMENTS: Electric - 1/60/120V, 20A GFI Compressed Air - ½ inch NPT @ 80 psi Cat 5e or Cat 6 communication cable

Refer to specification sheets for specific details

105/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

HEPA FILTERED BEDDING DUMP STATION CABINET Model BSC 6000

FOR SAFELY CAPTURING AND REMOVING DUST, ALLERGENS & SUSPENDED AGENTS FROM LABORATORY ANIMAL WORKSTATIONS

DESCRIPTION: The BSC 6000 is a Class 1 BSC, HEPA filtered up draft cabinet for BSL-1 applications. The BSC 6000 is intended to protect personnel handling soiled cages by effectively removing suspended dust, allergens and other airborne agents. The BSC 6000 can be fitted on the Self Contained Dumpstation, SCD 6800, or onto bench tops, carts or other dump stations.

Clear acrylic construction of the BSC 6000 supports dual HEPA filter units, each having 300 CFM (500 CFM free flow) blowers and polyester pre-filters. The large front sash opening of 52” wide by 22” high frame with 8” or 12” wide soft vinyl side panels accommodates cage handling comfortably while maintaining an effective average face velocity of 100 fpm. An 11” high rear sash opening is provided with a flexible vinyl panel for pass-through applications, such as those when dump stations are located in front of conveyor type cage washers.

FEATURES:

CAPTURES DUST AND ALLERGENS – The BSC 6000 enclosed cage dump operation runs with interior negative pressure air flow and HEPA filtration. Out performs all down draft stations, for eliminating dust and particle exposure to operators.

FLEXIBLE & COMFORTABLE – The front sash opening of the BSC 6000 is fitted with adjustable and flexible vinyl panels to provide average air velocity of 0.5 m/s or 100 fpm (range 80 to 120 fpm). The vinyl panels allow for optimal freedom of movement within the cabinet without compromising the face air velocity to capture the dust and allergens.

VERSATILE – The BSC 6000 is made for use with the SCD 6800 Dump-station, but may also be used as a table top hood or adopted for use with existing, non-Roe, dump-stations. Can be used as a Fume Hood when used with the appropriate optional filters.

BSC 6000 HEPA Filtered Hood Mounted on the SCD 6800 Self Contained Dumpstation

DIMENSIONS: 54" w x 26" d x 35.6" high A total of 75.6”, + 2” height adjustment, overall assembly height with SCD 6800 dump station. ELECTRICAL: 1/60/120V, 10A GFI Outlet NOISE LEVEL: 55 dBA COMPLIANCE & STANDARDS: NIOSH N100 rating, ETL, UL 3101-1/61010-1, ADA, SEFA 1-2002*, Federal Standard 209E certified class 100 table top clean room* (with appropriate optional filters).

OPTIONS: FILTERS – HEPA, Polyester Pre-filter, Carbon, Potassium Permanganate, Carbon/ Permanganate Combination. FLUORESCENT LAMPS – Surface mounted on cabinet top. UV LAMPS - 254 nm wave length, surface mounted on cabinet top. VARIABLE SPEED BLOWER SWITCH. GAUGE - Magnahelic®. CART BASES - Stainless Steel solid top, ADA compliant. TRASH BIN BASE - Stainless Steel top with 20 inch round chute. REFERENCES: Harrison, D.J., Controlling Exposure to Laboratory Animal Allergens, ILAR Journal, Volume 42, No.1, 2001 Barbeito, M.S. and Taylor, L.A. 1968. Containment of Microbial Aerosols in a Microbiological Safety Cabinet. Appl. Microbial. 16: 1255-29.

115/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

Self Contained Docking Bedding Dump Station –SCD 6800

PRODUCT COMPARISON TABLE

12

Vacuum Dump Station Only one waste port can be used at a time. Cannot be moved from installed fixed position ►Restricts access for cleaning other caging materials when placed in front conveyor wash equipment. ►Ergonomic stress from twisting and turning when placed to the side of conveyor wash equipment. ►Can only be used in cage wash area.

Controls – Switches only. Must be connected to main control system.

Operators are unaware of status of system function or status unless or until operation is disrupted.

Rotary valve and grinder models subject to binding with wet and caked material. Not compatible with liquids.

Grinders require manual separation of reusable environmental enrichment materials.

Facility is subject to retro-contamination from out-side sources if dump station is connected when system is not operating. Subject to retro and cross contamination from room-to-room or from outside if dump station is connected when system is not operating. Cannot be sterilized.

Roe Biomedical Products Self Contained Docking Bedding Dump Station Multiple Vacuum Ports may be used at the same time when used with the SCD 6800 operating synchronously with the alternate locations.

Moveable ►Moveable feature with the conveyor wash equipment facilitates the cleaning of various caging types and accessories. ►Ergonomically preferred placement is easily achieved by each individual operator. ►May be used as a portable dumpstation in any location, then reconnected to the vacuum bedding removal system at a later time.

Controls - Independent built-in PLC for mobility stand alone application and VBRS system interface. BAS capable with data acquisition and assembly.

Graphic Touch Panel Interface with embedded graphics and self-diagnostics. Make it easy for operators to understand the status of the entire system. Waste separating valve handles wet, dry or caked waste animal bedding. Will also accept liquids.

Environmental enrichment materials may be mechanically separated and / or shredded.

Patented Separating Valve is self-closing to maintain the integrity of the facility whether or not the system is operating. Each Local Port Valve closes when dump station or system is not in operation, preventing potential retro or cross contamination from room to room or from outside the facility. Entire system can be sterilized in place (SIP). Simple routine SOP’s for both CIP and SIP.

5/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

AUTOMATED DUMP STATION - ADS 6900

Automated Bedding Dump Station

Automatically removes soiled bedding from cages and advances cages into tunnel wash machines (conveyor or indexing wash machines). Saves labor.

Mounts to the front of conveyor wash machines-Detachable Docking & Roll-Away feature that enables multiple use for tunnel type wash machines.

Eliminates the impact trauma to cages.

Mechanically inverts and empties any size plastic cages-up to 20 inches long and 12 inches high.

Reduces Carpal Tunnel Syndrome liabilities, saves labor and increases productivity.

Eliminates dust and allergen exposure to workers-Enclosed cage dump operation with interior negative air, out performs all down draft stations and laminar hoods for eliminating dust and particle exposure to operators.

FEATURES

Load or working height shall match the belt height of the associated tunnel washer. Stainless Steel Type 304 with #3-4 finish construction. Adjustable legs support the unit with ¾” SS threads and thermoplastic feet. Both upper and lower screen/grid assemblies are included:

o The upper assembly shall consist of an open arrangement of ½” diameter rods which shall form the working area.

o The lower assembly shall be complete with an interlock switch such that operation of the machine is halted if the grid is not in place and opened.

An updraft exhaust hood shall be mounted over the unit, and will include a fan producing 600-800 scfm at ½” s.p. with HEPA or Rigid Filter option.

BRIEF SYNOPSIS OF ACTION

Cages are loaded by the operator into the Automated Dump Station, right side up. The operator then initiates the dump sequence when the inverter is loaded by depressing the “start” icon on the Graphic Touch Panel Interface. The cages are then electronically sized for length. When the conveyor of the wash machine has sufficient room for cages, the safety shield retracts, the enclosed inverter then clamps the cages and rotates (inverts) the cages 180, dumping their contents onto the grid inside the chute. If the Water Jet option is exercised, the inside the cages are flushed with air jets to remove any excess debris. The cages are released and then ejected into the conveyor wash.

Dimensions: </=52”W x 84”H (to top exhaust hood) x 32”D TYP. Component Requisite: Vacuum Waste Management Systems Options:

Vacuum wand and hose with switching valve assembly. Casters, locking stainless steel assemblies with 4” polypropylene wheel and Delrin bearings. Docking latch, aligns and latches / de-latches dump station onto the conveyor wash. Casters required. Inferred interface equipment monitor (P/N 69-500-00) Water Jet Flush (P/N 69-100-00) Air Compressor Package (P/N 00-690-02)

Utility Requirements:

Electrical – 1/60/120V, 20A

Compressed Air - ½” NPT @ 80 psi 2 SCFM Water (with optional Water Jet Flush) - 2 GPM max.

091404z

135/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

AUTOMATED VACUUM WASTE BAGGING SYSTEM VBRB 7000

FOR LABORATORY ANIMAL BEDDING REMOVAL DESCRIPTION:

The VBRB 7000 is an automated bagging system for soiled laboratory animal bedding and feed. The VBRB 7000 weighs, fills and seals the soiled bedding materials in standard pre-made bags. Sealed bags can be surface decontaminated, autoclaved, composted (ASTM 6400) or incinerated.

Configured with a Vacuum Bedding Removal System, soiled bedding is received from one or more work stations via a vacuum transport line. The VBRB 7000 then opens individual bags from the cartridge stack. Soiled bedding is automatically proportioned into the bag by weight or volume, and the bag is automatically thermo sealed. It is ideal for bio-containment and satellite facilities or for incineration operations. FEATURES:

ERGONOMICALLY PROACTIVE - Reduces the risk of Musculoskeletal Disorders (MSDs) and other injuries caused by lifting, resulting in less time off and greater productivity.

REMOVES DUST & ALLERGENS – Fully contained, vacuum air carries away the dust and allergens, generated by the bedding materials. The vacuum air is cleaned by filtering it through a pocket filter or optional HEPA filter, leaving the work area uncontaminated.

HIGH EFFICIENCY & CAPACITY – Automated weighing and filling operation eliminates intensive labor. Fills up to 20 bags per minute.

LOW NOISE - less than 70db @ 2’ (Cabinet).

FAST INSTALLATION - Compact size, allows flexibility in system location, including rooms with restrictive height limitations.

NEMA 4X - stainless steel construction permits use in wet locations including wash down areas.

BAGS:

AUTOCLAVE (to 121º C / 250º F). Colors: clear or red. BIO-HAZARD, (ASTM D1709-04,165g dart drop standard). Color: red. COMPOST (ASTM # 6400, #D6400-99 and EN 13432 standards). Color: off white.

VBRB 7000

OPTIONS:

Decontamination rinse for post filled & sealed bags. Rinse maybe liquid sterilant, aqueous solutions or water. Incline conveyor, moves sealed waste bags to tilt carts, or other take away containers.

Available in 40” and 48” working heights, with 1/3 hp, 120 volt drive motors. Equipment Wash-down Package, USDA / CFIA compliant.

UTILITY REQUIREMENTS:

Electrical - 120 v, 60 Hz, 1, 20 Amps for 3.5 hp, 13-12/6 Amps for 5 hp Compressed Air – 3.5 SCFM @ 90 PSI

Refer to specification sheets for specific details

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Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

MULTIPLE PORT VACUUM BEDDING REMOVAL SYSTEM MPVBRS FOR REMOVING LABORATORY ANIMAL BEDDING FROM MORE THAN ONE LOCATION

DESCRIPTION:

The MPVBRS combines multiple vacuum bedding removal Work Stations and a vacuum bedding removal system such as a VBRS 9400 or a Vacuum Bedding Bagging System. Multiple Work Stations can be located in any convenient area, such as: animal holding rooms, change stations or central cage wash areas. Work Stations may be Self Contained Dump Stations or a Vacuum Wand Station consisting of a graphic touch screen microcomputer with built in communication and data management capability options. Work stations are isolated from each other, on the main conveying line by a synchronous rapid acting valve to prevent cross contamination from location to location and waste receptacle.

Vacuum bedding removal systems, such as a VBRS 9400 or a Vacuum Bedding Bagging System, VBBS 7000, combine the separating valve, vacuum blower, filtration system, controls, drive motor and environmental controls into a single unit. The unit may be located either inside or outside the building. Soiled bedding is discharged into any Compactor, Dumpster, Incinerator, Continuous Feed Sterilizer, Digester, Tilt Cart or Bin, including non-dedicated compactors or bagging equipment.

FEATURES:

ERGONOMIC ENHANCEMENTS - Improved productivity and reduced exposure to MSD injuries and hazardous materials.

REMOVES DUST & ALLERGENS – Fully contained, vacuum air carries away the dust and allergens. The vacuum air is cleaned by multiple filtration steps, including membrane pocket filter and optional HEPA filter, leaving the work area and exhaust air uncontaminated.

ENERGY EFFICIENT – The ISO 9000 manufactured separating valve permits Poly Dense Phase conveying, requiring 1/10th the energy compared to dilute phase to move equivalent amounts of material. Fully documented by empirical tests and published data. MULTIPLE PORT VACUUM

BEDDING REMOVAL SYSTEM

VERSATILE WORK STATIONS – Multiple workstations may be located in isolator change stations, safety cabinets or on bench tops, up to 700 feet from the discharge.

QUIET – No noise at workstation, under 70db @ 2’ (Cabinet)

EASY MAINTENANCE - The entire system can be cleaned and sterilized in place with liquid sterilants, without the need for dismantling or disruption of service. Serviceable non-proprietary parts are readily available of the shelf.

EASY INSTALLATION AND MAINTENANCE - Compact size, convenient to locate and does not require sealed dumpsters, water, drains, or other special facility design considerations.

OPTIONS:

Model SCD 6800 - Self Contained Docking Bedding Dump Station. FOR STAND ALONE APPLICATIONS OR IN CONJUNCTION WITH CONVEYOR TYPE CAGE WASHERS

UTILITY REQUIREMENTS:

Discharge Cabinet: 208-230/460 v, 60 Hz, 3, 30/15 Amps;120V, 60Hz, 1, 20 Amps, Cat6 communication cable, compressed air 80-90psi, ½ NPT Work Station: 120V, 60Hz, 1, 10 Amps, for workstation touch screen, located within four feet. Cat 6 communication cable, compressed air 90 psi, 1/2 NPT with disconnect

Refer to specification sheets for specific details

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125 Wilbur Pl. Bohemia, NY 11716

Multiple Port Vacuum Bedding Removal System

PRODUCT COMPARISON TABLE

OTHER SYSTEMS Vacuum Bedding Disposal System Discharges into a dedicated waste container. A separate additional container must be used for general refuse. Rotary valve subject to binding with wet material, not compatible with liquids. Facility is subject to retro-contamination from out-side sources when system is not operating. Cannot be sterilized. Interfaces with waste container using a Harting type or similar connector, requiring manual connections with threaded fittings for container instrumentation.

Waste hauler driver must disconnect and reconnect container as a separate operation.

Subject to damage if not disconnected when removing waste container.

Subject to corrosion and freezing in winter.

Operators are unaware of status of system function unless or until operation is disrupted. Controls are limited to operation of system. 144 ft. sq. minimum utility space requirement, with noise reducing hoods, dust collectors and ventilation. Only one waste port can be used at a time. >70 db @ 3’ with noise reducing hood.

Roe Biomedical Products Multiple Port Vacuum Bedding Removal System Discharges waste into a Non-Dedicated compactor, tilt cart or any other multiple user waste container. Patented Separating valve handles wet, dry or liquid waste animal bedding. Patented Separating Valve is self closing to maintain the integrity of the facility. Entire system can be sterilized in place (SIP). Interfaces with the waste container by utilizing a gravity plate for waste discharge.

Self contained sensors for container level and container in-place.

Waste hauler does not change routine. System detects the presence and status of the

waste container. Gravity plate slides automatically into position

when waste container is returned. Graphic Touch Panel Interface with embedded graphics and self-diagnostics. Make it easy for operators to understand the status of the entire system, including when remote waste container is full or not present; when dump station is at capacity. PLC has built in communication modem and data acquisition capabilities for in-house and/or remote system management and control. The self-diagnostic feature monitors the operating parameters. A no-net utility space requirement as a result of the Discharge & Platform, with separating valve, blower, filters, etc., shares the foot-print of the non-dedicated waste container. Dual Vacuum Ports may be used at the same time when used with the SCD 6800 operating synchronously with the alternate locations. >70 db @ 2’.

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125 Wilbur Pl. Bohemia, NY 11716

FAQ’s Q. How fast will it work? Can it keep up with my conveyor wash-machine? A. Yes, MODEL VBRS exceeds the process capacity of conventional conveyor wash-machines in the number of cages and the amount of material it can handle. Q. What about wet bedding from leaky water bottles or water valves? A. Yes, MODEL VBRS effectively removes soiled animal bedding and feed even if it is wet or slurry. Q. Do I need a special dumpster or compactor? Does it need to be sealed for a vacuum? A. Any conventional container or receptacle can be used, since no air-seal is required. A dust cover is recommended to keep debris from escaping and pests out of the container. Q. How loud is the system? A. The operator is exposed to a whisper of air. The noise at the Central Cabinet with the vacuum blower and motor is less than 70db. Q. Do I need to have MODEL VBRS located in a utility room or area? A. No, the Central cabinet has a small footprint and can be located anywhere (washroom, hallway, loading dock or closet, for example). Q. Can I place the system in a cage washroom? A. Yes, NEMA 4X construction allows MODEL VBRS to be placed in wash-down areas or outside, if desired. Q. Can it handle rabbit, dog and primate pans? A. Yes, wet, dry, or slurry MODEL VBRS removes even water and bulky matter effectively. It reduces the number of steps needed to clean them and most of the risk factors in lifting the pans. Q. How do you clean MODEL VBRS? A. Water or sanitizing solutions are drawn (vacuumed) through the transport tubing and valve. Filters are changed periodically as needed. Q. My facility is located in the basement below ground level, can MODEL VBRS lift wet bedding high enough to reach my dumpster? A. Yes, the MODEL VBRS has been demonstrated to and is successfully used to convey wet bedding up over two stories. Q. My facility is several stories above ground level and I can’t have it acute to where the dumpster is located. How will MODEL VBRS help me? A MODEL VBRS improves productivity by reducing the number of steps emptying, scraping and bagging waste bedding.

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125 Wilbur Pl. Bohemia, NY 11716

Helpful planning hints for the Vacuum Bedding Removal System (VBRS 9400)

A few simple considerations to assure optimal results:

Non-dedicated compactors are recommended whenever possible. Though a dumpster, tilt cart or

any receptacle can be used, the volume of material being discharged and the characteristic steep material mounding limit the available container capacity and require frequent container changes. Compactors can also be interfaced so that the VBRS is temporarily halted when the compactor is being manually charged with other material.

Elevate the material up to the highest level immediately rather than in steps. The transport

(conveying) tube should be installed directly above the work area and should rise vertically to the highest point before proceeding horizontally to the discharge. Consult factory if this installation layout is not feasible.

Long radius bends (elbows) of 6 ½ inches are recommended. Shorter radii will cause a centrifugal

effect, leading to potential blockages and tube wear. The more direct path with the fewer bends to the discharge point the, the more efficient the system will be.

Locate the Filter Cabinet (the blower and filter unit) near the point of discharge. The HEPA filtered

exhaust air is used as a heat trace and to keep the separating screens clear. The NEMA 4X construction and ultra quiet operation (less than 70 db) permits it to be located anywhere, peopled hallway or loading dock, inside or out, even in wash down locations. A 24 volt Control and Monitor Panel Box is located in the work area (cage washroom) for remote operation of the system.

Protect the transport tubing from outside weather and elements with a chase enclosure to the

discharge point. The transport tube is treated with a special static dissipative material that should be protected. Keeping the transport tube from temperature extremes improves its service reliability and life. The chase will also serve as housing for the electrical utilities and the exhaust airline to the Discharge Module containing the separating valve.

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Roe Bio-Medical Products

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125 Wilbur Pl. Bohemia, NY 11716

VBDS 4900 VACUUM BEDDING DISPENSING and BEDDING TRANSPORT SYSTEM

DESCRIPTION: The VBDS 4900 is a true vacuum bedding delivery system. The VBDS 4900 is a bedding dispenser and a vacuum bedding transport system all in one. The VBDS 4900 dispenser also includes an integral automated cage flipper and a dust collection system. The VBDS 4900 is ideal for paper pulp, paper chip, cob, wood chip and for a defined habitat type laboratory animal bedding.

BRIEF SYNOPSIS OF ACTION: Bedding is automatically conveyed from a storage system via the integral vacuum transport system and stored in the system’s hopper. The bedding is fluidized to assure that it will continuously flow then measured/metered and channeled into the dispensing chambers. The portion controlled bedding is now ready to be dispensed into the centers of the cages.

The VBDS 4900 automatically determines cage size and allots the precise required amount of bedding to the dispensing chambers. The system aligns the cages as they leave the cage washer conveyor then clamps and gently inverts (flips) cages 180° to right side up. The precise required amount of bedding is then dispensed into the center of each cage.

FEATURES:

HIGH THROUGHPUT – Adjustable to over 1000 cages per hour.

ERGONOMICALLY PROACTIVE - Reduces the risk of Musculoskeletal Disorders (MSDs) and other injuries caused by lifting, resulting in greater productivity.

COMPATIBLE – Will interface will most conveyor type cage washers.

SELF CONTAINED - Uses less space than conventional curtain style dispensers. Ideal for locations with restrictive floor space. Does not require utility pump room nor any special facility design considerations.

REMOVES DUST - Fluid vacuum air carries away the dust contained in the bedding product. The vacuum air is filtered through a bag filter or optional HEPA filter, leaving the work area uncontaminated.

OPTIMAL OPERATION – Eliminates the need for manual handling and loading. Works with paper pulp, paper chip, wood shavings and corn cob beddings.

MICROCOMPUTER CONTROLS – Windows based, easy to use and understand with self-diagnostic graphics, condition analysis and cage count functions. Available with remote communication options.

LOW NOISE – Produces less than 70db @ 2’ (Cabinet)

19

FAST INSTALLATION – The VBDS 4900 houses all the components required for the system to work. After connecting it to the cage washer and plugging it in, it only takes a short time to synchronize the computer, then just push start.

VBDS 4900

REQUISITE COMPONENT: Remote Bedding Storage System - pre-existing or selected options (see OPTIONS)

OPTIONS: Discharge Conveyors: Gravity Roller, Power Roller or 90º Power Roller Remote Bedding Storage Systems: VBBS Automatic Bag Slitter with integrated storage silo, Bin or Bulk Bag Discharger. Custom Sorting Conveyors: Separate cages from non-caging materials exiting the conveyor washers or various cage types.

UTILITY REQUIREMENTS: 480V -3 phase, 60 Hz, 40/30 AMP. 120V, 1/60/ 30 AMP Consult factory for 50 Hz or for special purpose applications Compressed Air – 80 psi, 8 CFM capacity, 4 CFM comsumption

VBDS 4900

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COMPARISON TABLE

ROE BIO-MEDICAL’S VACUUM BEDDING DISPENSING SYSTEM VBDS4900

Vs. CURTAIN TYPE DISPENSERS

FEATURES CURTAIN STYLE VBDS4900 BENEFITS Dispense Method Re-circulated Blanket of

Bedding with Dust Generation

Proportioned/Measured Dispensed to Center of Cages Only

No wasted material, Reduced Maintenance

Cage Inversion None/Drop Type Automatic/Mechanical Extended Cage Life Cage Alignment None/manual Automated No Operator Required Residual H2O Elimination

None Automated Pre-Dispensed

Post Wash Separation System

None Automatic PWSS 90

Adds flexibility to Tunnel Washer. No Operator Required.

Integration to Trolley

None Automatic Reduced Labor

Vacuum Transfer (Loading)

Not Available Integrated Vacuum Conveying System

Reduced Labor and Allergen Exposure

Dust Collection Separate unit Requiring additional Floor space

Internal to System No additional floor space required

Microcomputer Control

None Graphic Touch Panel Self Diagnostic Time and Date Stamp Tracking of Product

Consumption Cage Counts

Bedding Types Cob Yes Yes Chip Yes Yes Paper Difficult Yes Care

Fresh/Tek Fresh

None Yes

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BULK BAG DISCHARGERS - BBDS FOR DELIVERY OF LABORATORY ANIMAL BEDDING

DESCRIPTION: The BBDS is a Free Standing Bedding Discharge System that stores laboratory animal bedding, eliminating the need for storage silos and wasteful material handling. When combined with the Vacuum Bedding Transfer System (VBTS 9000) it automatically discharges the clean bedding to the bedding dispenser. FEATURES: ERGONOMICALLY PROACTIVE - Reduces the risk of Musculoskeletal Disorders (MSDs) and other injuries caused by lifting, resulting in less time off and greater productivity. REMOVES DUST – The enclosed unit eliminates dust, and does not generate any additional contaminants in the air.

21

BULK BAG BEDDING DISCHARGER

PORTION CONTROL DISPENSING – The built in meter dispenses the correct amount of bedding and maintains the correct amount of bedding in thdispenser.

e

VERSATILE – The single discharger can supply one or more dispensers. A dual discharge unit will provide true seamless operation. SAFE OPERATION – The system was engineered with safety in mind. There are no augers or belts. OPTIONS: Automatic crossover manifold. UTILITY REQUIREMENTS: Electrical - 120 v, 20 Amp, single phase

DUAL BULK BAG STAINLESS STEEL CONSTRUCTION

Refer to specification sheets for specific details

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125 Wilbur Pl. Bohemia, NY 11716

AUTOMATED BEDDING STORAGE SYSTEM VBSS 1000

FOR STORING LABORATORY ANIMAL BEDDING DESCRIPTION:

The VBSS 1000 is an Automated Bedding Storage System equipped with a Bag Slitter/Opener, and Storage Silo. It was designed to use with standard bedding packaging (15 to 100 lbs., 36”W x 40”L x 14”H max.). The Storage Silo is located below the bag slitter and has a 1.5 cu yd capacity. The bedding is vacuum transported to one or more locations, and to any style bedding dispenser. The dust is removed from the transferred bedding through the vacuum process. The dispenser bin maintains optimal levels of bedding, so the bedding flows evenly and consistently through the dispenser, without creating additional dust. FEATURES:

ERGONOMICALLY PROACTIVE - Reduces the risk of Musculoskeletal Disorders (MSDs) and other injuries caused by lifting, resulting in less time off and greater productivity.

REMOVES DUST – Contains an integrated filtering system for dust collection, leaving the work area uncontaminated.

HIGH EFFICIENCY & CAPACITY 6-10 bags opened per min. 1.5 cu.yd. storage capacity

MICROCOMPUTER CONTROLS – Windows based program is easy to use and understand with self-diagnostic graphics, and condition analysis.

FAST INSTALLATION - Compact size, allows flexibility in system location, including rooms with restrictive height limitations. OPTIONS: UTILITY REQUIREMENTS:

Electrical - 208-230/460 v, 60 Hz, 3, 50/25 Amps, (to be located within four feet of the bag slitter) Electrical - 208-230/460 v, 60 Hz, 3, 5 Amps 120V, 60Hz, 1, 5 Amps, for discharge and touch screen, Compressed Air - 5 SCFM @ 60-80 psig

refer to specification sheets for specific details

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

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AUTOMATED BEDDING STORAGE SYSTEM-VBSS 1000

PRODUCT COMPARISON TABLE

Roe Biomedical Products: AUTOMATED BEDDING STORAGE SYSTEM VBSS 1000 Uses animal bedding materials in standard 15 to 100 lbs. (36”W x 40”L x 14”H max.) packaging. Single compact unit is designed for automated opening and storage of bedding product. Most laboratory animal bedding products can be used such as paper & wood pulp, chip or shavings, cob, etc. Any operator easily loads bedding packages onto waist level conveyor. System detects and stops loading when at capacity. 10 each 40# bags can be loaded in one minute. Emptied bags are quickly discarded. Sterilized bedding bags can be automatically surface sanitized or sterilized through an optional misting section. Sterility is maintained inside unit. Graphic Touch Panel Interface with embedded graphics and self-diagnostics. Makes it easy for operators to understand the status of the entire system, including when to recharge the system with bedding. PLC has built in communication modem and data acquisition capabilities for in-house and/or remote system management and control. The self-diagnostic feature monitors the operating parameters. System may be recharged with product at any time, even when partially full, without disruption of either delivery operation or bedding dispenser operation. Discharge with separating valve is floor mounted over bedding dispenser and discharges bedding into the dispenser hopper, for a no net floor space requirement. Filter cabinet with vacuum blower is 20” d x 32” w. >70 db @ 2’.

OTHER SYSTEMS: Bulk Bag

Vacuum Bedding Dispensing System Limited to products available bulk bag packaging. Requires lift hoists, trolleys, loading funnel, safety rails and other infrastructure considerations. Limited to flowable bedding products from a few vendors. Requires trained personnel for potentially hazardous overhead hoist lift, placement onto loading funnel and manual opening of bulk bags. Replacing each 400# bulk bag takes a minimum of 15 – 25 minutes. Handling of the emptied bulk bag can easily double this labor. Bulk bedding is easily compromised, if sterile, at loading funnel.

Operators are unaware of status of supply or system function unless or until operation is disrupted. Controls are limited to operation of system. System operation is halted during bulk bag change over and cannot be scheduled. Loading Cyclone is ceiling mounted with vacuum unit located in penthouse. Minimum utility space requirement of 144 ft. sq. with noise reducing hoods, dust collectors and ventilation. >70 db @ 3’ with noise reducing hood.

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VACUUM BEDDING TRANSFER SYSTEM 23

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VBTS 9000

FOR TRANSPORTING OF LABORATORY ANIMAL BEDDING DESCRIPTION:

The VBTS 9000 is a computer operated Vacuum Bedding Transfer System that automatically transports laboratory animal bedding from a remote bedding storage area to any bedding dispenser via a transport tube. Proven lift to 10 stories. The VBTS 9000 is ideal for paper pulp, paper chip, cob, wood chip and for a defined habitat type laboratory animal bedding.

The bedding is discharged from the system into the bedding dispenser at ambient (room) pressure. The bedding continues to be conveyed until the sensor set point is reached. When the set point is reached, the bulk discharger stops, but the vacuum conveyor continues (for a fixed period of time), purging the transport tube of any remaining bedding.

FEATURES:

ERGONOMICALLY PROACTIVE - Reduces the risk of Musculoskeletal Disorders (MSDs) and other injuries caused by lifting, resulting in less time off and greater productivity.

REMOVES DUST - Fluid vacuum air carries away the dust, generated by the bedding product, to the point of the separating valve. The vacuum air is cleaned by filtering it through a bag filter, leaving the work area uncontaminated.

CONTINUOUS MATERIAL FLOW – The patented separating valve enables an uninterrupted flow of bedding to the dispenser, increasing the conveying efficiency and speed.

VBTS 9000

OPTIMAL OPERATION – Maintains the maximum amounts of bedding in any type dispenser, eliminating the need for manual transportation.

HIGH EFFICIENCY & CAPACITY - Uses one tenth the power of comparable systems: Conveying capacity 1.5 cu meters/hr (2cu yd. /hr).

LOW NOISE – Produces less than 70db @ 2’ (Cabinet)

FAST INSTALLATION – The VBTS 9000 houses all the components required for the system to work, (separating valve, blower motor, filtration cabinet, microcomputer, and all associated wiring).Simply connect it to the dispenser and plug it in. Being self-contained it can be used in locations with restrictive room, such as over bedding dispenser hoppers. In addition, it does not require any special facility design considerations.

EASY MAINTENANCE – Changing filters, adding lubricant, and basic routine maintenance is all that is required.

UTILITY REQUIREMENTS:

480V -3 phase, 60 Hz, 40/30 AMP. 120V, 1/60/ 30 AMP Consult factory for 50 Hz or for special purpose applications Compressed Air – 80 psi, 8 CFM capacity, 4 CFM comsumption

refer to specification sheets for specific details

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125 Wilbur Pl. Bohemia, NY 11716

245/13/2009 ENGINEERING for LABORATORY ANIMAL SCIENCE MANAGEMENT & CARE ©

VACUUM BEDDING TRANSFER SYSTEM VBTS 9000

FOR DELIVERY OF LABORATORY ANIMAL BEDDING AND FEED Automatically transfers bedding and feed from bulk bags or storage silos to bedding dispensers. Maintains the optimum levels of product in dispensers for efficient, dust free operation. The elimination of manual material handling, typically by one FTE and the associated injuries. Frees space required for product storage and equipment. Ideal for locations with constricted space and reduced utilities. Low cost and maintenance. May be used with most any bedding or feed product.

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Model 9400 VDS

EMERGENCY

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http://www.roebiomed.com

Model 9400 VDS

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CONTROLS CENTRAL & INTERFACECABINET: FILTER & BLOWER

3DISCHARGE VALVE & ASSM.BEDDING DISPENSERREMOTE CONTROL & INDICATOR, 24VCONTROL CABLE WIRERETURN VACUUM AIR

OPERATION OF THE BULK BEDDING TRANSFER SYSTEM Bedding is proportionately emptied from the bulk discharger (2) and is vacuum conveyed to one of the bedding dispensers (5) via the transport tube (3). At the bedding dispenser (5) the bedding is separated from the vacuum air in the separator valve (4) in the Discharge Valve Assembly. The bedding is discharged from the valve into the bedding dispenser hopper at ambient (room) pressure. The bedding continues to be conveyed until the sensor set point in the hopper is reached, at which point the bulk discharger stops and the vacuum conveyor continues for a fixed period of time, purging the transport tube of bedding. Dust is removed from the bedding in the separator valve. The dust is collected first in the cyclone separator (9) followed by filtration in the cabinet (11).

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CLEAN BEDDING PACKAGING SYSTEMS VBPS 7000

FOR IN-HOUSE PACKAGING OF LABORATORY ANIMAL BEDDING, ENRICHMENT AND FOOD

DESCRIPTION:

The VBPS 7000 is an automated bagging system for in-house packaging laboratory animal bedding, enrichment and feed, into discrete packages and pouches. Pouch styles and sizes are selected for suitable use in isolator change stations, satellite facilities or field operations. Single use pouch styles may be flat or self standing, sealed or with a re-sealable zipper and are supplied with breathable bio-barrier reemay membrane filters. Sealed pouches can be surface decontaminated and autoclaved.

The VBPS 7000 automatically opens individual standard pre-made pouches from the loading cartridge stack. Bedding is then manually filled or automatically proportioned into the pouch by weight or volume. Enrichment materials or feed can be manually added or substituted for the bedding. The pouch is then automatically thermo sealed and the next pouch is readied for filling.

FEATURES:

ERGONOMICALLY PROACTIVE - Reduces the risk of Musculoskeletal Disorders (MSDs) and other injuries caused by lifting, resulting in less time off and greater productivity.

REMOVES DUST & ALLERGENS – Fully contained, vacuum air carries away the dust and allergens, generated by the bedding materials. The vacuum air is cleaned by filtering it through a pocket filter or optional HEPA filter, leaving the work area uncontaminated.

HIGH EFFICIENCY & CAPACITY – Automated weighing and filling operation eliminates intensive labor. Fills up to 20 bags per minute.

LOW NOISE - less than 70db @ 2’ (Cabinet).

FAST INSTALLATION - Compact size, allows flexibility in system location, including rooms with restrictive height limitations.

NEMA 4X - stainless steel construction permits use in wet locations including wash down areas. POUCHES:

AUTOCLAVABLE (to 121º C / 250º F). Colors: clear or red. POUCH STYLES: Flat or Self Standing, optional re-sealable zipper style

supplied with breathable bio-barrier reemay membrane filters SIZES: Flat pouch 4” to 20” wide X 20 long Self Standing pouch 4” to 12” wide x 12” to 20” high

OPTIONS:

Incline conveyor, moves sealed waste bags to tilt carts, or other take away containers. Available in 40” and 48” working heights, with 1/3 hp, 120 volt drive motors.

Equipment Wash-down Package, USDA / CFIA compliant. UTILITY REQUIREMENTS:

Electrical - 120 v, 60 Hz, 1, 20 Amps for 3.5 hp, 13-12/6 Amps for 5 hp Compressed Air – 3.5 SCFM @ 90 PSI

Refer to specification sheets for specific details

Roe Bio-Medical Products

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125 Wilbur Pl. Bohemia, NY 11716

FREE STANDING BEDDING DISPENSER

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VBDS 3000 FOR DISPENSING LABORATORY ANIMAL BEDDING

DESCRIPTION: The VBDS 3000 is a Free Standing Bedding Dispenser that houses a Bin, a Proportioner, and a Dispensing Head. The system manually dispenses bedding into cages, two at a time. The Dispensing Head can also be supported by a 3000 series Articulated Balancing Arm for ease of handling, and reduced risk of repetitive motion injury. In addition, the bins can be automatically filled using the VBTS 9000 Vacuum Bedding Transfer System from a VBSS Automatic Bag Slitter (opener) with integrated Storage Silo or a Bulk Bag Discharger, or by using an Auto Loading System series ALS 9000 from standard bedding packages.

FEATURES:

ERGONOMICALLY PROACTIVE - Reduces the risk of Musculoskeletal Disorders (MSDs) and other injuries caused by lifting, resulting in less time off and greater productivity.

REMOVES DUST – The enclosed unit eliminates dust, and does not generate any additional contaminants in the air.

PORTION CONTROL DISPENSING – The built in meter dispenses the correct amount of bedding according to cage size. SAFE OPERATION – The system was engineered with safety in mind. There are no augers or belts. OPTIONS:

Vacuum Transfer Systems series VBTS 9000 Automatic Bag Slitter with integrated silo VBSS

Component Requisite: Auto Loading System series ALS 9000 UTILITY REQUIREMENTS:

Electrical - 120 v, 20 Amp, single phase

VBDS3000

refer to specification sheets for specific details

Roe Bio-Medical Products

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125 Wilbur Pl. Bohemia, NY 11716

CAGE INVERTERS – CIS6000 FOR DISTRIBUTING LABORATORY ANIMAL BEDDING

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DESCRIPTION: MODELS 6200 & 6400 Cage Inverters can be mounted directly to the off-load conveyor of the wash machine and used in conjunction with the Series 4000 Automatic Bedding Dispensers or other dispensers. MODEL ADS 6900 Automatic Dump Station- incorporates the cage inverter to automatically remove soiled bedding from cages and advance them into tunnel wash machines. It can be used in conjunction with Model VBRS 9400. It mounts to the front of conveyor wash machines. FEATURES: MECHANICALLY INVERTS CAGES - Cages coming out of the conveyor wash machine are automatically separated, aligned and inverted, ready to be filled with clean bedding. It is designed for use with any plastic cage up to 20 inches long and 12 inches high. SAFE CONVEYOR OPERATION – The line shaft design permits conveyor roller rotation to be individually interrupted without injury. ELIMINATES IMPACT TRAUMA – Unlike drop type inverters, this unit gently inverts cages, reducing breakage. MICROCOMPUTER CONTROLS – Windows based program is easy to use and understand with self-diagnostic graphics, condition analysis, and cage count functions. ERGONOMICALLY PROACTIVE - Reduces Carpal Tunnel Syndrome liabilities and labor. DIMENSIONS: 85” l x 42” w x 78” h UTILITY REQUIREMENTS: Electrical - 120 v, 20 Amp, single phase. Compressed Air- - 2 SCFM

refer to specification sheets for specific details

Roe Bio-Medical Products

www.roebiomed.com(631) 236-9155 Fax (631) 289-4126

125 Wilbur Pl. Bohemia, NY 11716

RESOURCE SECTION 29

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Continuous Improvement Program OHS Allergies Lab Animal Magazine Article-Jan 1999

“Vacuum Disposal System” Lab Animal Magazine Article-Jan 2002 “Cage

Processing and Waste Management-A Cost Analysis and Decision-Making Exercise”

How It Works-Vacuum Conveying for Soiled Bedding Removal

Spare Parts Physical Activities, Conditions and

Ergonomic Risk Factors in Lab Animal Care Facilities

Process Time and Costs Calculation Time Motion Studies (Example) VBS Utility Requirements Volume & Weight Conversions Customer List

Roe Bio-Medical Products

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125 Wilbur Pl. Bohemia, NY 11716

CONTINUOUS IMPROVEMENT PROGRAM Through the implementation of accepted and proven disciplines, used in various manufacturing operations today, the Roe Bio-Medical continuous improvement program, initiated in 2007, is showing very encouraging results.

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Root Cause Analysis

Data gathered from field service, customer installed base, engineering, development, and manufacturing is logged into a pareto chart. The pareto chart identifies 20% of system problems that cause 80% of the failures. This allows us to focus on the top 3-5 issues and take the corrective action needed with a timely and methodical approach. These strategic actions are reviewed monthly to determine progress. Decisions are made on documented specifications and then incorporated into the test bed. A pre determined “burn-in” timeframe is adopted and the EC (engineering change) is evaluated at the conclusion. At this time the decision is made to either incorporate this change or take a different approach. All successful EC’s are then locked in as part of system design going forward. EC’s that are system fixes are turned over to field service to be installed at all customer locations, ec’s that are system enhancements are offered as upgrades for customers to evaluate and purchase if they choose to do so. Overall System Quality

Roe Bio-Medical Products is encouraging a “partnership” philosophy with our customer base. This partnership will be crucial for gathering data to enable Roe Bio-Medical to evaluate system performance and make the necessary changes to increase overall availability time. These communications may also indicate user operations that need to be evaluated and modified for system optimization. Data required for CIP

MTBF: Mean time between failure. Daily system availability log needs to be kept by the customer. This log simply identifies that the system is running or is down needing repair or maintenance. This log should run on a weekly basis and only cover the timeframe that a system can be used. For example if the lab runs 24/7 the benchmark would be 168 hours. We will tailor this to each individual location.

MTTR: Mean time to repair. When it is determined that a system is down due to failure we want

to track how long it takes to bring the system back on line. Using these two data points we can determine system availability time. This tracking method has not yet been implemented at our installed base but will be initiated by our field service group and with the approval of our customers it is our hope that we will start gathering this data in Q4 ’08. Conclusion

The continuous improvement program is a proven entity that Roe Bio-Medical has adopted to mature our tool set and enable us to offer LAS systems that will perform reliably. We have taken measures that have already sown significant results, however we need the working partnership with our customers, outlined above, to make the biggest leap forward for the mutual benefit.

Roe Bio-Medical Products

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OCCUPATIONAL HEALTH AND SAFETY

ALLERGIES

IN THE LABORATORY ANIMAL FACILITY Dec. 2006

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There is an extensive body of literature on laboratory animal allergies. Enclosed are relatively concise reference articles in pdf format as listed below. We offer them as a starting point for your program. The ILAR Journal (http://dels.nas.edu/ilar_n/ilarjournal/journal.shtml) is a particularly useful source for this information.

OCCUPATIONAL HEALTH & SAFETY

Cullinan, et al., 1994: Prospective study of new workers with no previous rat exposure:

• Range of 30-1369 days from time of employment to onset of symptoms.

• Mean duration of employment before symptom onset was:

214 days for nose and eye symptoms

335 days for skin symptoms

365 days for chest symptoms

• Assuming regular exposure, in general, most who develop allergies will do so within 3 years of employment

• One third are symptomatic in the first year, 70% within 3 years

• About 70% of those who eventually develop asthma will do so within 3 years of developing initial allergy symptoms

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The Occupational Health and Safety Tables are a useful visual showing allergy incidence rates with the original data found in the literature. Between 11 and 44% of the individuals working with laboratory animals report work-related allergic symptoms. Of those who become symptomatic, 4 to 22% may eventually develop occupational asthma that can persist even after exposure ceases1,2,3. Employee Medical Surveillance Programs, such as the NIH Animal Exposure Surveillance Program4 have been widely adopted to identify and assist departments and organizations in dealing with issues of employees exposed to animals in the work place. Overall, laboratory animal allergy incidence rates have not significantly changed since the issue was first identified. Administrative approaches and PPE’s have been shown to reduce the incidence rates with some success. Engineering controls are regarded as the most effective means to control allergen and aerosol exposure to employees5. Costs associated with laboratory animal allergy incidences have been markedly escalating in recent years. Successful claims ranging to over $200,000.00 are not unheard of (customer communication). Even when a claim is not made the costs have significant impact on an organization arising from lost time, retraining, reporting and associated administrative time. At present we are working on a paper for the industry directed at these costs and would like you to participate, if you are interested. While OSHA does not have a standard that specifically applies to occupational asthma, OSHA will be targeting sites that report 12 or more injuries or illnesses resulting in lost time from work, work restrictions, or a job transfer for every 100 full-time workers. The following standards can be used to address safety from OA causal agents (source: http://www.labsafety.com/refinfo/ezfacts/ezf214.htm)

OSHA Act of 1970, General Duty Clause 5(a)(1). Title 29 Code of Federal Regulations (CFR) 1904, OSHA’s Recording and Reporting

Occupational Injuries and Illnesses. Title 29 CFR 1910.134, OSHA’s Respiratory Protection Standard.

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OCCUPATIONAL HEALTH & SAFETYAoyama, et al., British Journal of Industrial Medicine, 1992

26% mice25% rats31% guinea pigs30% rabbits26% hamsters25% dogs30% cats24% monkeys

of workers exposed toof workers exposed to of workers exposed to of workers exposed to of workers exposed to of workers exposed to of workers exposed to of workers exposed to

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Probably the largest cross sectional study involving lab animal allergies:

REFERENCES: (1) Bush RK, Stave GM, Laboratory animal allergy: an update. ILAR Journal. 2003;44(1):28-51 (2) Wolfle, Thomas, Robert Bush, Science and Pervasiveness of Laboratory Animal Allergy, ILAR Journal, Volume 42, No.1, 2001 (3) Le, Richard, Janice Dodge, Report on Exposure to Animal Allergens in the Biomedical Research. Facility – March 21, 2003. Background. On March 6, 2003, Environmental Health and Safety, Florida State University, Tallahassee http://www.safety.fsu.edu/animalallergens-brf.pdf (4) NIH Animal Exposure Surveillance Program, medical support for workers with animal contact. Program covers employee health and safety information and documentation; immunization; clinical evaluation and treatment. (5) Harrison, D.J., Controlling Exposure to Laboratory Animal Allergens, ILAR Journal, Volume 42, No.1, 2001

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125 Wilbur Pl. Bohemia, NY 11716

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41

September 2008

Roe Bio-Medical Products

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125 Wilbur Pl. Bohemia, NY 11716

CONSUMABLE PARTS PART # DESCRIPTION PRICE

VACUUM HOSE SUPPLIES 00-082-16 (1) Lift hose 1½ “ x 8’ with quick coupling $ 172.80 00-082-17 Lift hose 1½ “ x 10’ with quick coupling $ 185.50 00-082-18 Lift hose 1½ “ x 12’ with quick coupling $ 197.00 00-082-15 Lift hose 2 “ x 8’ with quick coupling $ 189.50 00-082-19 Lift hose 2 “ x 10’ with quick coupling $ 202.60 00-082-14 Lift hose 2 “ x 12’ with quick coupling $ 212.80

00-082-05 Nozzle – 1½” standard slant tip $ 21.50 00-082-07 Nozzle – 1½” formed end $ 102.00 00-082-01 Nozzle – 2” standard slant tip $ 32.00 00-082-03 Nozzle – 2” formed end $ 142.00 00-082-28 (1) 2" SS Quick sanitary quick clamp $ 28.00 00-082-27 (1) Quick coupling gasket, 5/pack $ 43.30

FILTERS 94-003-21 (1) Filter, HEPA, 95-97% – Interchangeable $ 377.00 94-003-22 (1) Filter, Rigid, 90-95% – Interchangeable $ 92.00 94-003-10 (1) Filter Bag, Fiberglass pocket $ 38.10 94-003-12 Filter, Activated charcoal– Optional $ 39.00

OTHER PARTS 00-942-20 (1) Impeller, cyclone separator valve $ 107.70 00-020-15 Shaft Coupler L095 Body, 3/4" bore $ 19.22 00-020-16 Shaft Coupler Body L095, 7/8" bore $ 19.20 00-020-10 Coupling, Spider for L095 style coupler $ 28.60 00-020-15 Shaft Coupler L075 Body, 3/4" bore $ 18.10 00-020-12 Coupling, Spider for L075 style coupler $ 21.06 00-900-50 6" Discharge hose assembly with flange $ 84.88 00-900-51 6" quick clamp $ 21.26 00-083-10 End Cap, 2" Neoprene $ 8.73 00-081-08 Tool Balancer $ 72.35

NOTES: (1) Supplied with the original equipment.

Prices are subject to change without notice and exclude: taxes, surcharges, fees, tariffs and shipping, if any.

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42

LAB ANIMAL CARE TASKS

PHYSICAL ACTIVITIES AND CONDITIONS

ERGONOMIC RISK FACTORS

CAGE WASH LOAD & UNLOADING, WATER BOTTLE CAPPING

Doing same motion over and over again

Repetition Force Awkward postures

CONVEYOR WASH OPERATION, LAMINAR FLOW HOODS

(e.g. variations personnel height)

Working surfaces are too high or too low

Awkward postures Static postures Force Contact stress

LAMINAR FLOW HOODS, etc. Workstation edges or objects press hard into muscles or tendons

Contact stress

EMPTYING RODENT CAGES, FILLING CAGES WITH BEDDING

Using hands or body as clamp to hold object while performing tasks Using hand as hammer

Force Static postures Awkward postures Contact stress

CONVEYOR WASH OPERATION, CAGE CHANGES, WATER BOTTLES

Manual handling (lifting/lowering, pushing/pulling and carrying)

Force Repetition Awkward postures Static postures

MOVING/LIFTING: FEED, BEDDING, WATER BOTTLES,

SOILED BEDDING BAGS, LARGE CAGES

Objects moved are heavy Force Repetition Awkward postures Static postures Contact stress

RETRIEVING & CAGE CHANGING ON RACKS, WATER BOTTLE & PAN CHANGES, FEEDING, CAGE WASH RACK LOADING

Vertical reach is below knees or above the shoulders (Distance of hands above the ground when the object is grasped or released)

Force Repetition Awkward postures Static postures Contact stress

CONVEYOR WASH OPERATION Bending or twisting during manual handling

Force Repetition Awkward postures Static postures

PLASTIC CAGES, CAGE TOPS, WATER BOTTLES

Object is slippery or has no handles

Force Repetition Awkward postures Static postures

CAGE WASH ROOM ACTIVITY Floor surfaces are uneven, slippery or sloped

Force Repetition Awkward postures Static postures

PHYSICAL ACTIVITIES, CONDITIONS AND ERGONOMIC RISK FACTORS IN LAB ANIMAL CARE FACILITIES *

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A QUICK METHOD OF CALCULATING PROCESS TIMES AND COSTS: By examining the steps involved during cage preparation for cleaning, the handling of waste bedding is clearly the most time consuming. Typical steps are outlined in “Time Motion Study Example.” A quick method to determine the potential cost savings for your facility is provided below. The example used below is derived from actual studies where conveyor wash machines had 30” wide conveyor belts with drive speeds between 60” per minute and 75” per minute. The cages were standard shoeboxes.

. Find the Potential Direct Labor Savings in your facility by first supplying the following: Total hours to wash (process) cages with the conveyor wash in your facility________ Total number of cages processed per day with the conveyor wash in your facility______ Conveyor Belt Speed (count the number of one inch links per minute) ________ 1. Find the Optimal Conveyor Output (cages/minute) = conveyor belt speed (inches/minute)

Cage length (inches/cage) x number of cages across conveyor

Example If: the conveyor belt speed is = 60 inches / minute The length of a shoe box cage is = 12.625 (125/8) inches 4 cages are washed across the conveyor belt

Then: 60”/min 12.625” x 4 cages across = 19 cages / min

2. To find the optimal process time for the number of cages processed per day, divide the Number of Cages Processed per Day by the Optimal Conveyor Output

Example If: Optimal Conveyor Output = 19 cages / minute 1000 cages are processed per day

Then: 1000 cages 19 cages/min. = 52.6 minutes (0.88 hr)

3. To find the Potential Process Time Savings, subtract the Optimal Process Time in hours per day from the Actual Process Time in hours per day

Example If: Actual Process Time = 5.21 hr / day Optimal Process Time = 0.88 hr / day Then: Potential Process Time Savings = 5.21 hr - 0.88 hr = 4.33 hr/day

4. To find the Potential Direct Labor Savings multiply Potential Process Time Savings in hours per day by the Number of Employees required to operate the equipment

Example If: Potential Process Time Savings = 4.33 hr/day Number of Employees in cagewash = 2

Then: Potential Direct Labor Savings = 8.66 hr/day 2000 hr / year

. Finding the Indirect Labor cost use a simplified version of W. Edwards Deming’s formula. That is for every hour not needed to spend performing one task is an hour gained to spend on another task. e.g. 2000 hr/year saved processing cages = 2000 hours spent performing animal care or twice the hours gained.

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TIM

E - MOTION STUDY EXAMPLE ACTIVITY sec/cage

I) Cages are brought into wash room 20 -30 ft from dump station & conveyor wash, on racks or in stacks of 18 cages.

1) Cages stacks are moved to dump station a) Walk 20 ft to stacks: 8 sec. per stack of 18 cages 0.4444 b) Return to dump station: 30 sec. per stack of 18 cages 1.6667

2) Cages are emptied in the dump station and stacked: 12 cages/min 5.0000 3) Average of 36 cages to fill each bagged barrel in the dump station

a) Pull two barrels from under dump station: 1.2 sec 0.0167 b) Tie bag: 14-18 sec. each bag 0.5000

4) Push/pull two barrels 40ft to holding area in Wash room: 20 sec 0.2778 5) Lift and place 2 each 35-45# bags in plastic cart: 14.5 sec 0.2014 6) Return to dump station with two barrels: 17.3 sec 0.2402 7) Get plastic liner bag and reline each barrel: 27 sec 0.7500

II) Washing cages 1) Stacks of cages moved next to conveyor wash: 4 sec 0.1111 2) Turn on conveyor wash & load with each stack of 18 cages: 56.8 sec 3.1563

III) Removing bagged soiled bedding to dumpster located outside building, 24-30 bags/day

1) Move cart with 8 bags 290 ft to elevator: 116 sec 0.4028 2) Wait for elevator to arrive, doors to open, load cart, door close,

elevate 1 floor and door open: 4 min 0.8333 3) Move cart 30 ft on first floor to loading dock: 12 sec 0.0417 4) Move cart to 35 ft to dumpster: 14 sec 0.0486 5) Open dumpster tail gate: 20 sec 0.0694 6) Transfer eight 35-45# bags into dumpster: 58 sec 0.2014 7) Close dumpster tail gate: 9 sec 0.0313 8) Return to wash room with cart (steps 1-4): 6 min 22 sec 1.3264

lV) Mandatory rest periods and breaks (60 minutes/day) 3.6000 Total process time per cage: 18.7632 sec

PROCESS TIME (TIME MOTION STUDY) = 5.21 hours per day = 1355 hours per year OPTIMAL PROCESS TIME = 0.91 hours per day (54 min) = 236 hours per year LABOR SAVINGS = (TIME CURRENT - TIME OPTIMAL) X 2 employees = 2238 hours per year1 OTHER CONSIDERATIONS:

- Cost of each P.O. processing and purchasing of liner bags. - Handling, storage, and retrieval of liner bags. - Cleaning of bins, floor, laminar flow hood and wash equipment - Labor losses due to:

- Repetitive motion injury (wrist, elbow, shoulder, etc.) - Back injury (lifting and turning to invert and stack cages) - Dust inhalation, allergies, etc.

_________1 Defines direct labor only, and excludes indirect costs as: incongruity of work routine, benefits or other compensation.

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Vacuum Bedding System Utility Requirements Vacuum Power and Control Panels Vacuum Bedding Removal (VBRS)

Discharge Cabinet/Platform

Customer to supply service panel with knife switch or breakers and located within 4 feet of the platform or to be mounted on the discharge cabinet to support the following: 3/60/480V, 30 AMP, 5 Wire (locate at waste container) 1/60/120V, 20 AMP (locate at waste container) Compressed air 80-90 PSI up to 4 CFM (locate at waste container)

Inside Cagewash 1/60/120V, 10 AMP Single Phase, GFI outlet located within 4 feet of vacuum drop Compressed air 80-90 PSI up to 4 CFM

Vacuum Bedding Delivery, Dispense and Transfer 3/60/480V, 30 AMP, 5 Wire 1/60/120V, 20AMP Compressed air 80-90 psi up to 4 cfm

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125 Wilbur Pl. Bohemia, NY 11716

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125 Wilbur Pl. Bohemia, NY 11716

Roe Bio-Medical Products Customer List 1. Abbott Labs, Massachusetts: (1) System

2. Albert Einstein College of Medicine, NY: (4) Systems 3. Allergan, California: (1) System 4. Astra Zeneca, Delaware: (1) System

5. Beth Israel Medical Center, Massachusetts: (3) Systems 6. Bristol Myers Squibb, Ct. (2) Systems

7. Boehringer-Ingelheim, Connecticut: (2) Systems 8. Colorado State University: (2) Systems

9. Cornell University, NY: (2) Systems

10. Johnson and Johnson, NJ, PA & California: (3) Systems 11. Kansas University, (1) System 12. Medical College of Georgia, Georgia: (2) Systems 13. Millennium Pharmaceuticals, Massachusetts: (1) System 14. NIH, Maryland: (2) Systems

15. Novartis, Massachusetts&California: (3) Systems 16. Penn State, Pennsylvania: (1) System 17. Regeneron Pharmaceuticals, NY: (2) Systems 18. Salk Institute, California: (2) Systems 19. Scripps Institute, California: (1) System 20. Shire Pharmaceutical, Massachusetts: (1) System 21. Stony Brook University, NY: (2) Systems

22. Tufts University, Massachusetts: (1) System

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Roe Bio-Medical Products Customer List (cont) 23. UMASS Medical, Massachusetts: (2) Systems 24. University of Kentucky, Kentucky: (1) System

25. University of Virginia, Va. (1) System

26. USC, California: (1) System 27. Wyeth Research, Massachusetts: (1) System 28. Yale University: (2) Systems 48 Systems Total

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