retinopathy in youth with type 2 diabetes participating in the today clinical trial featured...
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![Page 1: Retinopathy in Youth With Type 2 Diabetes Participating in the TODAY Clinical Trial Featured Article: TODAY Study Group* Diabetes Care Volume 36: 1772-1774](https://reader035.vdocuments.us/reader035/viewer/2022062805/5697bfd61a28abf838cadcb6/html5/thumbnails/1.jpg)
Retinopathy in Youth With Type 2Diabetes Participating in the
TODAY Clinical Trial
Featured Article:
TODAY Study Group*
Diabetes Care Volume 36: 1772-1774
June, 2013
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STUDY OBJECTIVE
• To determine the prevalence of retinopathy in 517 youth with type 2 diabetes of 2–8 years’ duration enrolled in the TODAY study
TODAY Study Group* Diabetes Care 2013;36:1772-1774
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STUDY DESIGN AND METHODS
• Retinal photographs were graded centrally for retinopathy using established standards
TODAY Study Group* Diabetes Care 2013;36:1772-1774
![Page 4: Retinopathy in Youth With Type 2 Diabetes Participating in the TODAY Clinical Trial Featured Article: TODAY Study Group* Diabetes Care Volume 36: 1772-1774](https://reader035.vdocuments.us/reader035/viewer/2022062805/5697bfd61a28abf838cadcb6/html5/thumbnails/4.jpg)
RESULTS
• Retinopathy was identified in 13.7% of subjects
• Prevalence increased with age, diabetes duration, and mean HbA1c
• Subjects in the highest BMI tertile had the lowest prevalence of retinopathy
TODAY Study Group* Diabetes Care 2013;36:1772-1774
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CONCLUSIONS
• Prevalence of retinopathy and its association with HbA1c and diabetes duration is similar to that in youth with type 1 diabetes and adults with type 2 diabetes of known duration
• Mechanism underlying the reduced risk of retinopathy in the most obese individuals is unknown
• Follow-up of this cohort will help define the natural history of retinopathy in type 2 diabetic youth
TODAY Study Group* Diabetes Care 2013;36:1772-1774
![Page 6: Retinopathy in Youth With Type 2 Diabetes Participating in the TODAY Clinical Trial Featured Article: TODAY Study Group* Diabetes Care Volume 36: 1772-1774](https://reader035.vdocuments.us/reader035/viewer/2022062805/5697bfd61a28abf838cadcb6/html5/thumbnails/6.jpg)
TODAY Study Group* Diabetes Care 2013;36:1772-1774