RESEARCH & DEVELOPMENT Reticulose reduces viral load in mv infection

After daily treatment with the peptide nucleic acid agent reticulose* on alternate weeks for a 60-day period, 21 patients with HIV infection had an average 21 % decrease in HIV viral load from baseline and a mean 37% increase in CD4+ count from baseline, according to the preliminary results of a study conducted in Barbados.

In contrast, 22 patients who received placebo had a 33% increase in viral load and a 7% decrease in CD4+ .cell counts, compared with baseline. At the end of the study period, the mean mv viral load of reticuloserecipients was 42% of that of controls.

72% of reticulose recipients maintained or increased their bodyweight, compared with 30% of controls.

No adverse effects, and 'zero toxicity' were associated with reticulose treatment. - PR Newswire, http://www.newspage.com; 11 Dec 1996 * Advanced Wrol Research; in clinical trWJs for HIV infection

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1173-832419611068-0oo71$01 .0rf' Adls International Limited 1996. All rights reserved Inpharma'" 21 Dec 1996 No. 1068

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