November 19-20, 2010Hotel Nikko, San Francisco, CA

A Continuing Medical Education Conference

SPONSORED BY STANFORD MEDICINE

BREAKTHROUGHS IN NEUROLOGIC THERAPIES:Restoring Function to the Nervous System

Statement of NeedNeurology, Neurosurgery and Psychiatry are medical specialties which require physicians to maintain board certification. ACGME Mainte-nance of Certification core competencies for quality patient care include:

• Patient Care• Medical Knowledge• Interpersonal and Communication Skills• Professionalism• Systems-based Practice• Practice-based Learning and Improvement

Physicians certified by the American Board of Psychiatry and Neurology or the American Board of Neurological Surgeons are required to complete a specified number of hours of AMA PRA Category 1 accredited education towards maintenance of certification. This conference contributes to this requirement. Consistent with the national focus on healthcare quality, neurologists, neurosurgeons, interventional radiologists, PM&R (rehabilitation physicians), neuro-oncologists, ER attendings, internists, family practice physicians, physician assistants, nurse practitioners and nurses are tasked with imple-menting the most comprehensive, up-to-date, evidence-based information on the treatment of patients with Neurologic disorders. These clinical updates will be provided to attendees at Break-throughs in Neurologic Therapies.

Target AudienceThis course is designed to meet the educational needs of an international audience of neurolo-gists, neurosurgeons, interventional radiologists, PM&R (rehabilitation physicians), neuro-oncolo-gists, emergency medicine physicians, internists, family practice physicians, physician assistants, nurse practitioners and nurses.

Learning ObjectivesAt the conclusion of this educational activity, par-ticipants should be able to:

•Apply current American Academy of Neurology Practice Guidelines to optimally diagnose and treat epilepsy.

•Apply American Heart Association best practice guidelines to optimally treat and prevent stroke.

•Apply new approaches for optimal diagnosis and treatment of movement disorders.

•Summarize latest developments in the use of antiangiogenic and new drug therapies for optimal management and treatment of brain tumors.

•Perform neuroendocrine evaluation following traumatic brain injury and treat any hormone deficiencies.

•Employ new approaches and emerging developments to optimally diagnose and treat Alzheimer’s Disease.

•Optimally consider and recommend timely neurosurgery for patients with Parkinson’s Disease.

•Summarize current research on the use of direct modulation of neural circuitry in the treatment of resistant psychiatric illness.

•Differentiate between neuromuscular disorders and cervical and lumbar radiculopathies and provide appropriate and timely treatment.

•Describe the benefits of and strategies for treating chronic pain following spine surgery with spinal cord stimulation.

AccreditationThe Stanford University School of Medicine is accredited by the Accreditation Council for Con-tinuing Medical Education (ACCME) to provide continuing medical education for physicians.

Credit DesignationStanford University School of Medicine desig-nates this educational activity for a maximum of 14.25 AMA PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

California Board of Registered NursingLucile Packard Children’s Health Services is approved by the California Board of Registered Nursing (Provider Number CEP 12570) to provide continuing education for Nurses. This course is approved for 17.00 contact hours.

American Board of Psychiatry and NeurologyThe American Board of Psychiatry and Neurol-ogy has reviewed Breakthroughs in Neurologic Therapies: Restoring Function to the Nervous System and has approved this program as part of a lifelong learning program, which is mandated by the American Board of Medical Specialties as a necessary component of maintenance of certification.

Conference Location Hotel Nikko, San Francisco, CASee back page for hotel information.

FacultyAllfacultyareaffiliatedwithStanfordUniversityMedicalCenter.Course DirectorsGregory W. Albers, MD Coyote Foundation Professor of Neurology and Neurological Sciences Director, Stanford Stroke Center Jaimie M. Henderson, MD Associate Professor of Neurosurgery, and, By Courtesy, of Neurology and Neurological Sciences Robert and Ruth Halperin Faculty Scholar Director, Stereotactic and Functional Neurosurgery Co-Director, Neural Prosthetics Translational LaboratoryFacultySteven D. Chang, MD Professor, Department of Neurosurgery Robert C. and Jeannette Powell Professor in the NeurosciencesRobert Dodd, MD, PhD Assistant Professor, Department of Neurosurgery and RadiologyJeffrey Dunn, MD Associate Professor, Neurology and Neurological Sciences Associate Director, Stanford Multiple Sclerosis CenterRobert S. Fisher, MD, PhD Maslah Saul, MD Professor of Neurology Director, Comprehensive Epilepsy Center

Michael D. Greicius, MD, MPH Assistant Professor, Neurology & Neurological Sciences Assistant Professor (By Courtesy), Psychiatry & Behavioral Science Medical Director, Stanford Center for Memory Disorders Department of Neurology and Neurological SciencesOdette Harris, MD, MPH Acting Associate Professor, Neurosurgery Director, Brain Injury, Stanford University School of Medicine Associate Chief of Staff, Polytrauma Director, Defense Veterans Brain Injury Center, VHA Palo Alto, CALaurence Katznelson, MD Professor of Neurosurgery and Medicine (Endocrinology, Gerontology, and Metabolism) Medical Director, Stanford Pituitary CenterFrank M. Longo, MD, PhD George and Lucy Becker Professor Chair, Department of Neurology and Neurological SciencesStefan A. Mindea, MD Assistant Professor of Neurosurgery Director, Minimally Invasive Spinal SurgeryMartha J. Morrell, MD Clinical Professor of NeurologyKathleen Poston, MD, MS Assistant Professor of Neurology and Neurological Sciences Division of Movement DisordersLawrence Recht, MD Professor of Neurology Director, Adult Neuro-OncologyYuen So, MD, PhD Director, Residency Program Director, Neurology Clinic Professor of Neurology and Neurological SciencesHugh Brent Solvason, MD, PhD Associate Professor of Psychiatry Medical Director, Psychiatric Neuromodulation ServiceGary K. Steinberg, MD, PhD Bernard and Ronni Lacroute-William Randolph Hearst Professor of Neurosurgery and the Neurosciences Director, Stanford Institute for Neuro-Innovation and Translational Neurosciences Chairman, Department of NeurosurgeryLawrence Steinman, MD Professor of Neurology and Neurological SciencesChristine A.C. Wijman, MD, PhD Associate Professor of Neurology and Neurological Sciences Director, Neurocritical Care, Stanford Stroke Center Hong Yu, MD Clinical Assistant Professor of NeurosurgeryGuest FacultyJohn W. Day, MD, PhD Professor of Neurology, Pediatrics, and Genetics, Cell Biology and Development Director, Paul and Sheila Wellstone Muscular Dystrophy Center University of Minnesota School of Medicine Minneapolis, Minnesota

Faculty DisclosureThe Stanford University School of Medicine and Stanford Hospital & Clinics adhere to ACCME Essential Areas, Standards, and Policies regard-ing industry support of continuing medical education. Disclosure of faculty and commercial relationships will be made prior to the activity.

CONFERENCEOVERVIEW

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PROGRAM(subject to change)

ENROLLMENTAPPLICATION

Friday, November 19, 2010NEURODEGENERATION/MS SESSION7:00-8:00 am Registration and Breakfast with Faculty8:00-8:05 am Welcome and Announcements Greg Albers. MD8:05-8:45 am Alzheimer’s Disease: An Update on Imaging and Diagnostics Michael Greicius, MD8:45-9:25 am Latest Developments in Therapeutic Approaches to Alzheimer’s Disease Frank Longo, MD, PhD 9:25-10:05 am Recent and Emerging Therapies for Parkinson’s Disease Kathleen Poston, MD, MS10:05-10:25 am Break10:25-11:05 am Stratification of Multiple Sclerosis via Predictive Biomarkers to Guide Therapeutic Decisions Lawrence Steinman, MD11:05-11:45 am Pulling Back the Curtain on MS Clinical Trials Jeffrey Dunn, MD11:45-1:00 pm Lunch and Keynote Speaker Neuromuscular Disorders Come Into Focus: Impending Treatments for Muscular Dystrophy John Day, MD, PhD

STROKE AND NEUROSURGICAL/NEUROCRITICAL CARE EMERGENCIES SESSION1:00-1:45 pm Treatment and Prevention of Ischemic Stroke: Current Standards and Innovative Approaches Greg Albers, MD 1:45-2:25 pm Endovascular Treatment for Acute Ischemic Stroke Robert Dodd, MD, PhD2:25-3:10 pm The Renaissance of Cerebrovascular Surgery Gary Steinberg, MD, PhD3:10-3:25 pm Break 3:25-4:05 pm Neurocritcal Care Cases Christine Wijman, MD, PhD4:05-4:45 pm Neurocritical Care Emergencies Odette Harris, MD, MPH5:15-6:15 pm Welcome Reception

Saturday, November 20, 2010 SPINE/NEURO-ONCOLOGY SESSION7:30-8:00 am Breakfast with Faculty8:00-8:05 am Welcome and Announcements Jaimie Henderson, MD8:05-8:45 am Hypopituitarism in the Setting of Brain Injury: An Evolving Field Laurence Katznelson, MD8:45-9:25 am Neuromuscular Mimics of Spine Diseases Yuen So, MD, PhD9:25-10:05 am Adult Spinal Deformity: Minimally Invasive Applications Stefan Mindea, MD

10:05-10:20 am Break10:20-11:00 am The Impact of Bevacizumab and Other Antiangiogenic Therapies on Brain Tumor Management Lawrence Recht, MD11:00-11:40 am Treatment of Brain and Spine Tumors: Surgical and Radiosurgical Innovations Steven Chang, MD11:45-1:15 pm Lunch on Your Own

NEUROMODULATION SESSION1:15-1:55 pm Spinal Cord Stimulation for Chronic Pain: Four Decades of Innovation Jaimie Henderson, MD1:55-2:35 pm Deep Brain Stimulation for the Treatment of Movement Disorders Hong Yu, MD2:35-3:20 pm Contemporary Treatment of Epilepsy Robert Fisher, MD, PhD3:20-3:35 pm Break3:35-4:15 pm Therapeutic Devices for Epilepsy Martha Morrell, MD4:15-5:00 pm Direct Modulation of Neural Circuitry in Treatment-resistant Psychiatric Disorders Brent Solvason, MD, PhD5:00 pm Adjourn

Opportunities for Q&A will be provided at the conclusion of each presentation.

Breakthroughs in Neurologic Therapies: Restoring Function to the Nervous System – November 19-20, 2010Please register early-hotel and conference space are limited. Registration fee includes welcome reception, Continental breakfasts with course faculty, lunch on Friday, course materials and certificate of attendance. Tuition may be paid by check, Visa, AmEx or MasterCard. Cancellation Policy: Refunds must be requested in writing by October 19, 2010, and will be subject to a $75 administrative fee. No refunds will be made on cancel-lations received after that date. Program materials cannot be guaranteed unless enrollment is received by October 19, 2010. Stanford University School of Medicine reserves the right to cancel this program; in the event of cancellation, course fees will be fully refunded.

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___________________________________________________________________NAME/DEGREE___________________________________________________________________SPECIALTY___________________________________________________________________MEDICALLICENSENUMBER(REQUIREDFORCMECREDIT)___________________________________________________________________AFFILIATION___________________________________________________________________STREETADDRESS___________________________________________________________________CITYSTATEZIP___________________________________________________________________DAYPHONEEVENINGPHONE___________________________________________________________________EMAILFAX

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StanfordUniversitySchoolofMedicineisfullyADAcompliant.Ifyouhaveneedsthatrequirespecialaccommodations,includingdietaryconcerns,pleasecontactbpannoni@stanfordmed.orgor(650)724-7166,beforeOctober19,2010.

Registration FeesEarly registration must be postmarked or faxed by October 19, 2010 Early Bird Discount After October 19, 2010Physician $495 $645AlliedHealthProfessional $300 $345Reception, Friday, November 19, 2010, Includedintuitionforcourseregistrants.Guest fee: $45.Iwillbring___guests.Breakfast with the Faculty: Breakfastisincludedintuitionforcourseregistrants.Guest fee: $50/two days.Iwillbring___guests.

Pleasecheckpaymentmethod:Register and pay online at www.cme.stanfordhospital.comCheck enclosed, payabletoStanfordUniversitySchoolofMedicine–SCCMEVisa American Express MasterCard

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Mail application and payment to: Stanford Center for Continuing Medical Education Attn:JeanHengst701-AWelchRoad,Suite2207,PaloAlto,CA94304

Phone:(650)723-7188Fax:(650)497-8585Email:jhengst@stanfordmed.orgWeb:www.cme.stanfordhospital.com

Hotel Nikko222 Mason Street, San Francisco, CA800.248.3308

AccommodationsA block of rooms is being held for conference participants. Rooms at these special rates have been reserved for attendees on a first-come, first-served basis and may sell out before the cut-off date. By staying at the host hotel, you assist Stanford University School of Medicine in meeting its contractual obligation with the hotel and in keeping future registration rates reason-able. Please contact the hotel directly at

(800) 248-3308 to make reservations. To receive the group rate of $169 per night, single or double occupancy, indicate that you are attending the Stanford University School of Medicine Break-throughs in Neurologic Therapies. Hotel Nikko reserves the right to close the room block 30 days before the conference. Group rates apply to nights booked by our attendees three days pre- or post-conference. For detailed hotel informa-tion visit: www.hotelnikkosf.com

Other ActivitiesFor information on local activities, please visit http://www.onlyinsanfrancisco.com/.

For questions about the symposium, please con-tact Barbara Pannoni, CME Coordinator, Stanford Center for Continuing Medical Education at (650) 724-7166 or email bpannoni@stanfordmed.org.

About Stanford Hospital & ClinicsStanford Hospital & Clinics is known worldwide for advanced treatment of complex disorders in areas such as cardiovascular disease, cancer treatment, neurosciences, surgery and organ transplant. Consistently ranked among “America’s Best Hospitals” by U.S. News and World Report, Stanford is internationally recognized for translat-ing medical breakthroughs into care of patients. For more information, please visit http://stanford-hospital.org.

For more information about Stanford School of Medicine Departments of Neurology and Neurosurgery, please visit:http://neurology.stanford.edu http://med.stanford.edu/neurosurgery/

ADDITIONAL CME PROGRAMMING OFFERED BY STANFORD HOSPITAL & CLINICS DEPARTMENT OF CONTINUING MEDICAL EDUCATION

Stanford 2nd Annual Surgical QualitySeptember 10-11, 2010

4th Annual Cardiology for the Primary Care PractitionerOctober 9, 2010

Stanford Otology & Neurotology Update 2010November 4-6, 2010

VENUE INFORMATION

Stanford Hospital & ClinicsStanford Center for Continuing Medical Education701-A Welch Road Suite 2207Palo Alto, CA 94304

Phone: (650) 724-7166 Fax: (650) 497-8585

www.cme.stanfordhospital.com

NONPROFIT ORGANIZATION

U.S. POSTAGE PAIDPALO ALTO, CAPERMIT NO. 188

BREAKTHROUGHS IN NEUROLOGIC THERAPIES:Restoring Function to the Nervous System

November 19-20, 2010Hotel Nikko San Francisco, CA

A Continuing Medical Education Conference SPONSORED BY STANFORD MEDICINE