responsive polymers for analytical and biosensing...
TRANSCRIPT
To whom correspondence should be addressed.E mail
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Abstract
Key Wordsresponsive polymers,
sensor,bimolecular,
analytical application,molecularly imprinted polymer
PolymerizationQuarterly, 2014
Volume 4, Number 2Pages 59-71
ISSN: 2252-0449
Responsive Polymers for Analytical and Biosensing Applications
Laleh Adlnasab*, Azadeh Pirisedigh, Samira OsatiDepartment of Polymer and Petrochemicals, Standard Research Institute, P.O. Box:
31745-139, Karaj, Iran
Received: 9 September 2013, Accepted: 28 June 2014
These days responsive polymers are used in a wide range of applications. Around the
world researchers have made efforts on responsive polymers with high performance
which respond to a variety of stimuli. The stimuli-responsive polymers have the ability
to respond physically and chemically in response to environmental changes. Also, these
materials have enormous potential in a wide range of modern industries. The environmental
In this paper, we focus on the analytical and biosensing applications. While polymer-based
systems can be engineered to respond to a single stimulus, they can also be made to respond
to multiple stimuli. Many applications associated with health, energy and the environment.
With so much chemical versatility and a wide reaching array of applications, the future is
bright for stimuli-responsive polymers.
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pH
ISSN: 2252-0449
DNA
pH
PNIPAM
(lower critical solution
°C temperature, LCST)
PNIPAM
LCST
pH
PNIPAM
(pNIPAm-co-acrylic acid, AAC PNIPAM
AAC
PNIPAM
pH
pH
PNIPAM-co-AAC
pH> Pka AAc
N N N
poly(2-(2-methoxyethoxy
-ethyl methacrylate-b-oligo(ethylene glycol)methacrylate-b
poly(N-isopropylacrylamide)
(hydrodynamic diameter, DH) DH ± nm pNIPAm-co-AAc
acrylic acid))
pH
°C °C
pH
pH
pKa
pH
ATRP
PNIPAM
PNIPAM HPLC
PIPAAm-brush-grafted silica-bead column(IP-B PIPAAm
poly(tert-butylacrylamide (tBAAm)-b-IPAAm) brush-grafted silica-bead column (tBIP-B
pH
PDPA PDEA
pH PDPA pH PDEA
PDPA HCl PDPA
pH PAA
pH
pH
pH
pH
FeCl3 CaCl2
pH
DNA
PBA
PNIPAM PBA
PDEA PDPA pH
pH
pH APBA
APBA
AAC PNIPAM
PHA PHA
PHA-Biotion PHA
PHA-Biotion
AAC NIPAM pH
A
PNIPAM
DNA
PHA-BIOTIN
PNIPAm-co-Aac PHA-BIOTIN
TNT
PS
CPS
PS
NIPAM RAFT
NIPAM
MIP
molecular imprinting
MIP
MIPC (molecu- mol
larly imprinted polymer capacitive
II MIP
II
MIP
A/μmol μ mol
III
CNTPE
SS-N26Gpul
LCST
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