respect-mil: early intervention & outcomes of ptsd ... · system 8 weeks or more, and have a...
TRANSCRIPT
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Charles C. Engel, MD, MPH
Associate Chair (Research), Department of PsychiatryUniformed Services University School of Medicine
Director, Deployment Health Clinical Center at Walter ReedSenior Scientist, Center for the Study of Traumatic Stress
RESPECT-Mil: Early Intervention & Outcomes of PTSD
& Depression in Primary Care
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Report Documentation Page Form ApprovedOMB No. 0704-0188
Public reporting burden for the collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching existing data sources, gathering andmaintaining the data needed, and completing and reviewing the collection of information. Send comments regarding this burden estimate or any other aspect of this collection of information,including suggestions for reducing this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215 Jefferson Davis Highway, Suite 1204, ArlingtonVA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to a penalty for failing to comply with a collection of information if itdoes not display a currently valid OMB control number.
1. REPORT DATE 2011 2. REPORT TYPE
3. DATES COVERED 00-00-2011 to 00-00-2011
4. TITLE AND SUBTITLE RESPECT-Mil: Early Intervention & Outcomes Of PTSD & DepressionIn Primary Care
5a. CONTRACT NUMBER
5b. GRANT NUMBER
5c. PROGRAM ELEMENT NUMBER
6. AUTHOR(S) 5d. PROJECT NUMBER
5e. TASK NUMBER
5f. WORK UNIT NUMBER
7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) Uniformed Services University School of Medicine,Department ofPsychiatry,4301 Jones Bridge Rd,Bethesda,MD,20814
8. PERFORMING ORGANIZATIONREPORT NUMBER
9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES) 10. SPONSOR/MONITOR’S ACRONYM(S)
11. SPONSOR/MONITOR’S REPORT NUMBER(S)
12. DISTRIBUTION/AVAILABILITY STATEMENT Approved for public release; distribution unlimited
13. SUPPLEMENTARY NOTES Presented Mar 21 at the 1st Annual Armed Forces Public Health Conference 2011
14. ABSTRACT
15. SUBJECT TERMS
16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT Same as
Report (SAR)
18. NUMBEROF PAGES
52
19a. NAME OFRESPONSIBLE PERSON
a. REPORT unclassified
b. ABSTRACT unclassified
c. THIS PAGE unclassified
Standard Form 298 (Rev. 8-98) Prescribed by ANSI Std Z39-18
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Why Primary Care?A Gap Between Needs & Services
Among the 20% of Soldiers with moderate to severe disorder after OIF deployment…
Hoge CW, et al. N Engl J Med. 2004;351:13-22.
Want help
Mental health
professional
Acknowledge
a problem
Got help (past 12 months)
Any
professional
13-27%38-45%
78-86%
23-40%
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Potential for Offset: Service Use & Missed Work
0
10
20
30
40
50
60
15+ on PHQ-
15
limb pain back pain 2+ sick call
visits/mo
2+ missed
work
days/mo
PTSD
No PTSD
Hoge et al, Am J Psychiatr, 2007
2,863 Iraq War returnees one-year post-deployment
Twice as many
sick call visits &
missed work days
Percen
t o
f S
old
iers
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4
Primary Care…Where Soldiers Get Their Care
Mean primary care use is 3.4 visits per year
88-94% have one or more visits per year
Primary care approach to mental health is an opportunity to…
Reduce stigma & barriers
Intervene early
Reduce unmet needs
Reduce unnecessary service use
4
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Primary Care Intervention is Evidence-Based
Randomized trials offer sound evidence that systems-level approaches benefit…
Depression (e.g., IMPACT Trial BMJ 2006)
Suicidal ideation & depression (Bruce et al, JAMA 2004)
Depression and physical illness (e.g., Lin et al, JAMA, 2003)
PTSD and physical injury (Zatzick, AGP, 2004)
Panic disorder (e.g., Roy-Byrne et al, AGP 2005)
Somatic symptoms (e.g., Smith et al, AGP 1995)
Health anxiety (e.g., Barsky et al, JAMA 2004)
Substance dependence (e.g., O‟Connor et al. Am J Med. 1998)
Dementia (e.g., Callahan et al, JAMA 2006)
5
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Defense Centers of Excellence for Psychological Health & TBI
Office of The Surgeon General, Army
Deployment Health Clinical Center
Uniformed Services University
3CM®
COLORADO SPRINGS, CO 5-7 OCTOBER 2010
RESPECT-MilRe-Engineering Systems of Primary Care Treatment in the Military
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3 Component Model
systems-based carePREPARED PRACTICE
BH SPECIALIST
PATIENTCARE MANAGER
an extra resourcethat links patient,
provider & specialist
Oxman et al, Psychosomatics, 2002;43:441-450
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Encourage AdherenceProblem Solve Barriers
Measure Treatment Response
Monitor Remission
RESPECT-Mil
Care Facilitator Functions
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RESPECT-Mil Worldwide Sites
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Levels of Implementation
Micro: Clinic level implementation
Meso: Site level implementation (R-SIT)
Macro: Program level implementation (R-MIT)
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RESPECT-Mil ImplementationMicro- or Clinic-level
Brief PTSD & depression screening (all visits)
Pre-clinician diagnostic aid
Patient education materials
Psychosocial options
Care Facilitator assisted follow-up option
Aggressive facilitator outreach & monitoring
Web-based care facilitation system
“Just-in-time” treatment adjustment
Weekly BH Champion review of facilitator caseload
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RESPECT-Mil ImplementationMicro- or Clinic-level
Brief PTSD & depression screening (all visits)
Pre-clinician diagnostic aid
Patient education materials
Psychosocial options
Care Facilitator assisted follow-up option
Aggressive facilitator outreach & monitoring
Web-based care facilitation system
“Just-in-time” treatment adjustment
Weekly BH Champion review of facilitator caseload
1
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RESPECT-Mil ImplementationMicro- or Clinic-level
Brief PTSD & depression screening (all visits)
Pre-clinician diagnostic aid
Patient education materials
Psychosocial options
Care Facilitator assisted follow-up option
Aggressive facilitator outreach & monitoring
Web-based care facilitation system
“Just-in-time” treatment adjustment
Weekly BH Champion review of facilitator caseload
1
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PT
SD
In
stru
men
t (P
CL
-C)
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RESPECT-Mil ImplementationMicro- or Clinic-level
Brief PTSD & depression screening (all visits)
Pre-clinician diagnostic aid
Patient education materials
Psychosocial options
Care Facilitator assisted follow-up option
Aggressive facilitator outreach & monitoring
Web-based care facilitation system
“Just-in-time” treatment adjustment
Weekly BH Champion review of facilitator caseload
1
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Provider “Fast Facts”
Participant Education &Self-Management Materials
Goals & Self-Management Worksheet
Participant Brochure
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RESPECT-Mil ImplementationMicro- or Clinic-level
Brief PTSD & depression screening (all visits)
Pre-clinician diagnostic aid
Patient education materials
Psychosocial options
Care Facilitator assisted follow-up option
Aggressive facilitator outreach & monitoring
Web-based care facilitation system
“Just-in-time” treatment adjustment
Weekly BH Champion review of facilitator caseload
1
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DESTRESS-PC - Web-based,
nurse assisted, PTSD self-training
DElivery of
Self-
TRaining &
Education for
Stressful
Situations –
Primary Care version
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RESPECT-Mil ImplementationMicro- or Clinic-level
Brief PTSD & depression screening (all visits)
Pre-clinician diagnostic aid
Patient education materials
Psychosocial options
Care Facilitator assisted follow-up option
Aggressive facilitator outreach & monitoring
Web-based care facilitation system
“Just-in-time” treatment adjustment
Weekly BH Champion review of facilitator caseload
1
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FIRST-STEPS – Web-based Care-
Manager Support & Reporting System
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RESPECT-Mil ImplementationMicro- or Clinic-level
Brief PTSD & depression screening (all visits)
Pre-clinician diagnostic aid
Patient education materials
Psychosocial options
Care Facilitator assisted follow-up option
Aggressive facilitator outreach & monitoring
Web-based care facilitation system
“Just-in-time” treatment adjustment
Weekly BH Champion review of facilitator caseload
1
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FIRST-STEPS – Improves Efficiency,
Accountability & Effectiveness of Staffing
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RESPECT-Mil ImplementationMacro- or Program-level
RESPECT-Mil Implementation Team (R-MIT):
Monitors program implementation, fidelity, outcomes
Trains & consults with R-SiTs
Develops & disseminates education modules and tools
Pilots & evaluates new components
Performs site visits & site calls
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RESPECT-Mil ImplementationMeso- or Site-level
RESPECT-Mil Site Team (R-SIT)
Primary Care ChampionMonitors local program & process
Behavioral Health ChampionMonitors facilitator caseloads
FacilitatorRN, 1 per 6K in eligible population
Administrative assistant1 per 10K in eligible population
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Web-Based PTSD &
Depression Training for
Primary Care Providers*
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* Includes suicide assessment training
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RESPECT-MilProvider Manuals
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3 Component Model
systems-based carePREPARED PRACTICE
BH SPECIALIST
PATIENTCARE MANAGER
an extra resourcethat links patient,
provider & specialist
Oxman et al, Psychosomatics, 2002;43:441-450
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RESPECT-Mil
Implementation Results
61 of 95 primary care clinics at 34 sites are implementing, with the remainder expected on line by July 2011.
86% of visits at implementing clinics screened in last 12 months (75% since January 2007; 2-5% at non-RESPECT-Mil clinics)
13% of all screened visits are positive (PTS or depression)
48% of positive screens result in a primary care diagnosis of „depression‟ or „possible PTSD‟
26% of positive screens receive other BH diagnoses (e.g., adjustment disorder)
29* Data through November 2010
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RESPECT-Mil Screening Visits*Steadily Rising Rate of Routine Screening*
30Data through November 2010
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Referrals for Enhanced BH Services*Referrals for Facilitation Nearly as High as to Specialist*
31* Data through November 2010
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Care Facilitation & PTSD Severity (PCL-C)*Number of facilitator visits associated with improvement*
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1 2 3 4 5 6 7+
Number of care facilitator contacts
* Data from RESPECT-Mil enrolled cases from 01 Feb 2007 to 31 Aug 2009 (N = 2,548)
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Care Facilitation & Depression Severity (PHQ-9) *Number of facilitator visits associated with improvement*
33
1 2 3 4 5 6 7+
Number of care facilitation sessions used
* Data from RESPECT-Mil enrolled cases from 01 Feb 2007 to 31 Aug 2009 (N = 2,548)
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RESPECT-Mil
Safety & Risk Management
Visits associated with any suicidal ideation
1% of screened visits (8.6% of screen positive
visits)
25% of visits involving suicidal ideation are rated
by provider as intermediate or high risk (“non-low risk”)
8,771 visits involved suicidal ideation
Frequent “save” anecdotes
* Data through November 2010
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RESPECT-Mil
Safety & Risk Management
Visits associated with any suicidal ideation
Appropriate risk assessment - 99.4% of
screened positive visits
Appropriate risk assessment - 99.9% of
screened visits
* Data through May2010
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RESPECT-Mil
Dispositions
66% assistance rateaccept/[accept + decline]
4% of all visitsinvolve recognition & assistance for previously
unrecognized mental health needs
36* Data through November 2010
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Real-time Aggregate Data ReportsPTSD Remission Trend – Region #1
**Remission is defined as the count of individuals who have an open episode in FIRST STEPS, have been in the system 8 weeks or more, and have a PCL score of 27 or less.
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Real-time Aggregate Data ReportsPTSD Remission Trend – Region #2
**Remission is defined as the count of individuals who have an open episode in FIRST STEPS, have been in the system 8 weeks or more, and have a PCL score of 27 or less.
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Real-time Aggregate Data Reports
PTSD Remission Trends by Region
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Quarterly Progress Report: Fort Alpha
Example of a High Performance Site
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RESPECT-Mil
Findings to Date
Often concerns about getting started
Once started, approach is acceptable and feasible for both Soldiers and providers
Enrolled soldiers show clinical improvement
Identifying & referring Soldiers with previously unrecognized and unmet needs
Enhanced safety and risk assessment capabilities
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RESPECT-Mil
Challenges & Road Ahead
Provider training and retraining
Expansion site training
Web-based training ongoinghttp://www.pdhealth.mil/respect-mil.asp
FIRST-STEPS performance reporting
Alcohol SBIRT demonstration in preparation
REHIP: triservice demonstration of a “blended” model
Intercalation with Patient Centered Medical Home
STEPS-UP: 5-year, 18-clinic controlled trial – intervention is blended + centralized care management + stepped psychosocial modalities
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RESPECT-Mil Central
Implementation Team
COL Charles Engel, MCDirector
Tim McCarthyDeputy Director
Sheila Barry, BAAssociate Director, Program Development & Training
Mark Weis, MDPrimary Care Health Proponent
David Dobson, MDBehavioral Health Proponent
Kelly Williams, RNNurse Proponent & Educator
Lee BalitonProgram Evaluation/IT Specialist
James HarrisProgram Manager
Justin Curry, PhDAssociate Director, Program Evaluation
Barbara CharlesAdministrative Assistant
Phyllis HardyAdministrative Assistant
Consultant TeamAllen Dietrich, MD
Professor of Family Medicine, Dartmouth Medical School
Thomas Oxman, MDEmeritus Professor of Psychiatry, Dartmouth Medical School
John Williams, MD, MSPHProfessor of Medicine, Duke University & Durham VA
Kurt Kroenke, MDProfessor of Medicine, Indiana University & Regenstrief Institute
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Advances in Psychosomatic Medicine 2004;25:102-22
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RESPECT-Mil
Patient Flow & Clinic Process
45
Already in BH /RESPECT-Mil 63%
New referral to BH care 16%
New referral to RESPECT-Mil 15%
New referral out to BH care 7%
BH care enhanced7.6% of visits
negative
episode complete86.6% of visits
negative
episode complete4.4% of visits
Negative PHQ & PCL 72%
No PCC Diagnosis 28%
PCC visit10.2% of visits
screenall visits
diagnostic aid13.4% of visits
positive
positive
enhanced BH care declined1.4% of visits
no diagnosis
“Possible PTSD”
and / or “Depression”
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RESPECT-MilTime & Workload
component % visits
All clinic patients 100.0%
Screen positive 13.4%
Diagnosis 10.2%
Suicidality 0.7%
estimated time / visit
2 minutes medic time
3 minutes medic time
10 minutes clinician time
25 minutes clinician time
46
Total Estimated Time Per VisitMedic = 2 + (0.134 x 3) = 2.4 min
Provider = (0.102 x 10) + (0.007 x 25) = 1.2 min
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47
RESPECT-Mil Creating Efficiencies
screen -~ 2 min medic time
NO provider time
screen+, dx+, suicide-~ 5 min medic~10 min provider time
screen+, dx+, suicide+~5 min medic~25 min provider time
~0.7%
~9.5%
~86.6%
~3.2% screen+, dx-~ 5 min medic time
NO provider time
~ 90% of visits require NO added provider time
~ 84% of added clinician time is for the 0.7% of visits at highest risk
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RESPECT-Mil Facilitator Use*Only 20.6% have four or more facilitator contacts*
48* Data from RESPECT-Mil enrolled cases from 01 Feb 2007 to 31 Aug 2009 (N = 2,548)
0%
5%
10%
15%
20%
25%
30%
35%
40%
45%
1 2 3 4 5 6 7 8 9 10 or
more
42.0%
17.4%
11.6%
8.8%6.2%
4.4%3.5%
1.6%2.0% 2.6%
Number of care facilitation sessions used
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Quarterly Progress Report: Fort Bravo
Example of an Average Performance Site
49
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Quarterly Progress Report: Fort Charlie
Example of a Low Performance Site
50
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DoD STEPS-UP
A 6-site (18 clinic) RCT
comparing 12-months of
collaborative PTSD &
depression care vs usual
primary care.
Intensified intervention…
• aggressive case management (behavioral activation, motivation enhancement,
centralized tracking)
• stepped psychosocial care
Stepped
Treatment
Enhanced
PTSD
Services
Using
Primary Care
Supported by a DoD grant (DR080409) from the Congressionally-
Directed Medical Research Program (CDMRP)
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STEPS-UP Investigators
CoinvestigatorsDouglas Zatzick, MD (UW, Seattle)
Brett Litz, PhD, MA (Boston Univ & VA)
Terri Tanielian, MA (RAND)
Christine Eibner, PhD (RAND)
Jürgen Unützer, MD, MPH (UW, Seattle)
Wayne Katon, MD (UW, Seattle)
Donald Brambilla, PhD (RTI)
Michael C. Freed, PhD (DHCC/USUHS)
Kristie L. Gore, PhD (DHCC/USUHS)
Laurel L. Hourani, PhD, MPH (RTI)
Becky Lane, PhD (RTI)
Site InvestigatorsChris Warner, MD (Ft Stewart, GA)
Kris Peterson, MD (Ft Lewis, WA)
Melissa Molina, MD (Ft Bliss, TX)
Mark Reeves, MD (Ft Carson, CO)
Anthony Noya, MD (Ft Polk, LA)
Pascale Guirand, FNP (Ft Bragg, NC)
Scientific AdvisorsAllen Dietrich, MD (Dartmouth)
John Williams, MD (Duke & Durham VA)
Kurt Kroenke, MD (Regenstrief Institute)
Kathryn Magruder, PhD (MUSC)
Charles Hoge, MD (Walter Reed Army Institute of Research)
Principal InvestigatorsInitiating: Charles Engel, MD MPH (USU / DHCC)
Partnering: Robert Bray, PhD (RTI International)
Partnering: Lisa Jaycox, PhD (RAND Corporation)