research interests and disciplines available at · web viewprofessor guru aithal, co-chairs...

THE UNIVERSITY OF NOTTINGHAMROLE PROFILE

THIS DOCUMENT CONTAINS DETAILS FORAN NIHR-FUNDED ACADEMIC CLINICAL ASSISTANT PROFESSOR (ACL)

WHICH WILL BE OFFERED TO ONE SUCCESSFUL CANDIDATEIN EITHER GASTROENTEROLOGY OR MEDICAL ONCOLOGY

FOR DETAILS OF THE ACL OPPORTUNITY IN GASTROENTEROLOGYPlease see post details from Pages 2 – 11 inclusive and Appendices Pages 20-26

FOR DETAILS OF THE ACL OPPORTUNITY IN MEDICAL ONCOLOGYPlease see post details from Pages 12 – 19 inclusive and Appendices Pages 20-26

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Job Title: NIHR Academic Clinical Assistant Professor (ACL) in Gastroenterology

School/Department: School of Medicine - NIHR Biomedical Research Unit Nottingham Digestive Diseases Centre

Salary: £31,301 - £54,199 per annum, depending on skills and experience

Contract Status: This post will be offered on a fixed-term contract for a period of 4 years (if full-time; up to a maximum of 6 years part-time) or until award of Certificate of Completion of Training (CCT), whichever is the shorterSuccessful applicants must be in post before 31 March 2015

Hours of Work: Full-time or Part-time (minimum 0.6 FTE)

Location: Queen’s Medical Centre, Nottingham

Reporting to: Professor Guru Aithal, Head of Nottingham Digestive Diseases Centre

The University of Nottingham seeks applications for an NIHR-funded Academic Lecturer (ACL) in Gastroenterology. The post is offered in competition with eligible applicants in Medical Oncology. Academic Clinical Lectureships (ACL) in Gastroenterology provide advanced integrated academic and clinical training for those pursuing a career in Academic Gastroenterology. The post will have a strong research commitment in gastroenterology research in conjunction with clinical training.

The PostIn this NIHR Academic Clinical Lectureship in Gastroenterology, the Clinical Lecturer will spend 50% of their time consolidating their clinical experience in General Internal Medicine (GIM) and Gastroenterology on the Health Education East Midlands (North) Training programme centred around Nottingham. The remaining 50% of their time will be spent in research. Time allocated to training and to academic work may be annualised, i.e. taken in blocks, as appropriate to successful candidate’s clinical and research training needs. The appointee will become a member of the well- developed Clinical Academic Training Programme in the School of Medicine, University of Nottingham (www.nottingham.ac.uk/go/catp). The programme provides support in integrated clinical academic training, with research funding applications, through networking, mentorship and with an annual research conference bursary.Whilst the post will be offered on a fixed term contract for a period of up to 4 years, or until award of CCT whichever is shorter, the Clinical Lecturer would be expected to develop plans for a post-doctoral or clinician scientist award, which may shorten the lectureship. On completion of their clinical training, the trainee should be fully qualified to apply for Clinical Associate Professor / Honorary Consultant posts. An Honorary Specialty Registrar contract will be sought from Nottingham University Hospitals NHS Trust.Details of the academic and clinical aspects of the post are given below.

Academic component of the Academic Clinical Lecturer (ACL) postsDuring the academic component of the post, the ACL will further develop their academic skills at postdoctoral level, build on their research in Gastroenterology, undertake research, develop their own research programme and compete for external grant funding. More details are given below.The academic part of the training will be tailored to individual needs of the Lecturer and their research interests. The ACL would be expected to further develop their track record in research and will have

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access to the research facilities of the Academic Division which has excellent laboratory, statistical and technical support. They will be expected to undertake research and, as part of their research portfolio, they will be expected to develop skills in research supervision through the supervision of the research component in the 3rd year of the BMedSci medical student degree. The ACL’s personal research programme would be expected to fit broadly within the research themes of the of Nottingham Digestive Diseases Centre, described in more detail below. Each ACL will have an academic supervisor with they will formulate their individual academic programme. The ACL will be expected to attend:

The weekly Gastroenterology educational meeting and case conference. The regular Gastroenterology research meetings. Other research meetings at the discretion of the supervisor. Conduct research. Publish at least one paper or at least two abstracts describing original research each year In most cases, to apply for a further, peer-reviewed externally-funded post-doctoral training

award (such as a Clinician Scientist Award, or an Intermediate or Senior Research Fellowship from the Medical Research Council, NIHR a major charity such as the Wellcome Trust, or another funding body).

Office and laboratory accommodation will be provided of Nottingham Digestive Diseases Centre at the Queen’s Medical Centre site of the University of Nottingham’s School of Medicine.

Research interests and disciplines available at Nottingham/Derby in the Nottingham Digestive Diseases Biomedical Research Unit (NDD BRU)The research interests of the NDD BRU are broad covering luminal gastroenterology, hepatology and gastrointestinal surgery. There is specific expertise in inflammatory bowel disease (IBD), peptic ulcer and H. pylori associated diseases, C. difficile infection, neurogastroenterology, cirrhosis and portal hypertension, non-alcoholic fatty liver disease, genetics of liver injury and chronic hepatitis C. Professor Guru Aithal, co-chairs the international drug-induced liver injury (DILI) consortium which has led to recent discoveries in genetic susceptibility to DILI; there is an on-going project investigating genetic and circulating biomarkers of DILI. He also established a translational research group in Nottingham investigating novel tests to stratify NAFLD, life style and pharmacological interventions in NAFLD. In collaboration with SPMMRC, there are a number of work streams developing MR methodology to evaluate chronic liver diseases. Dr Gordon Moran sub-specialises in IBD. He has collaborative projects with the Sir Peter Mansfield Magnetic Resonance Centre studying the neurohormonal axis using MRI technology in IBD. Parallel work with Professor Spiller is investigating the altered gut motility in Crohn’s disease patients. Other therapies to enhance food intake and body composition in IBD are being explored with the MRC Centre for Musculoskeletal Ageing. He is principal investigator in a number of IBD-related pharmaceutical-led studies at the NDD BRU. Dr Tim Card and Dr Joe West conduct a wide range of GI epidemiology and observational studies in many areas including IBD, GI bleeding, celiac disease and liver diseases. Professor Krish Ragunath is an academic endoscopist interested in advanced imaging and pre-cancer detection and treatment in the GI tract. Professor John Atherton conducts translational and basic research in Helicobacter pylori pathogenesis and mechanisms of upper GI diseases. Dr Neil Guha, Associate Professor in Hepatology is an expert in the development and evaluation of biomarkers in liver disease; he developed the concept of ‘clinical utility model’ of non-invasive markers of liver fibrosis; his current work includes stratification of chronic liver disease using tissue, serum and imaging markers both in primary care and hospital based cohorts. Dr Neil Guha and Prof Guru Aithal were winners of the National NHS Innovation Award in 2013.Prof Will Irving, Professor of Virology established ‘Trent HCV cohort’ in 1992; with the involvement of Drs Steve Ryder and Brian Thomson, this cohort has contributed to research of international importance in the last 2 decades. Recently Prof Irving set up HCV research UK, a national consortium with an ambition of collating 10,000 HCV patients; HCV research UK is hosted by Nottingham Digestive

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Diseases BRU. Patients and infrastructure of HCV research UK supports ‘STOP-HCV’, another MRC funded programme that aims to stratify HCV patients with in-depth phenotyping to optimize therapy.Prof Jonathan Ball leads the anti-HCV monoclonal antibody discovery programme; currently a EUFP7 funded study is evaluating the role of human monoclonal antibody in the prevention of post-transplant HCV. Prof Ball also leads pre-clinical evaluation of HCV vaccine candidates.Professor Robin Spiller’s research programme in neurogastroenterology focuses on pain and motility disturbance in IBS. Current projects include colonic MRI imaging and functional assessments in constipation. There are also ongoing projects studying the role of colonic gas and microbiota in IBS patients. Professor Chris Hawkey is interested in inflammatory bowel disease, non-steroidal anti-inflammatory drugs, cancer prevention and the conduct of clinical trials.Professor Yash Mahida is interested in mucosal biology (including GI stem cells) and C. difficile pathogenesis. We have many other research programmes, in which we are actively working to translate basic science to clinical practice. These include extensive internationally-competitive research in bacteriology and virology, as well as research on drug targets, delivery and formulation conducted in our award-winning School of Pharmacy. Further details of individual academic gastroenterologists and their research interests can be found at: http://www.nottingham.ac.uk/medicine/about/nddc/index.aspx

Teaching and Organisation Teaching is a core generic academic skill and the ACL will be expected to take an active role in contributing to undergraduate medical teaching: this may include lectures, tutorials, assisting with the organisation of clinical examinations in the Nottingham Medical School undergraduate curriculum and postgraduate teaching.

Anticipated Academic milestones3 months Project area and Main Supervisor decided (if not already done before taking up post)4 months Detailed research plan written and presented. Research commenced.12-16 At least two abstracts submitted to major meetings and/or at least one paper based on

12 months research in Nottingham submitted24-30 At least two further abstracts submitted to major meetings and/or at least one paper

based on 24 months research in Nottingham submitted Application made for Intermediate or Senior Research Fellowship from MRC, Wellcome months Trust, or other funding body

36-48 Leave the scheme to take up an Associate Professor post, but with some flexibility to complete research or clinical training as appropriate

Clinical Training During periods of clinical training, the successful candidate will undertake full clinical responsibilities of a Specialty Trainee on the North (Nottingham-centred) Carousel of the Health Education East Midlands (HEEM) clinical training rotation in GIM/ Gastroenterology where they will work alongside clinical-track colleagues to attain their remaining competencies in their Specialty Training. Applicants must, therefore, be eligible to hold an academic National Training Number (NTN(A)) and show evidence of academic achievement, including a higher research degree at PhD/DPhil or MD/DM level, and successful outcomes from previous clinical annual assessments (ARCPs). The post is open to those who are at, or within, 2 years of clinical training of attaining their CCT in specialty or subspecialty. Most benefit from the post will be obtained by those with at least 1 year of clinical training to complete.

The post will be part of the Health Education East Midlands (North) training programme in GIM and Gastroenterology. The rotation will be tailored to the training needs and research interests of the applicant. It is envisaged that these posts will usually be based at the Queens' Medical Centre of the

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http://www.nottingham.ac.uk/medicine/about/nddc/index.aspx

Nottingham University Hospitals NHS Trust. However, the overriding aim will be to provide the post holder with the opportunity to develop both their clinical and research expertise within Gastroenterology, which in some instances may involve working elsewhere within training posts in Nottingham/Derby/Mansfield. Establishing links with these centres may also provide further research opportunities, enhance access to clinical material and assist recruitment of patients to clinical trials. Clinical experience at a district general hospital is also required as part of training requirements and this will necessitate spending some clinical time out of the main research centre. The main aim of the clinical component is to complete training in Gastroenterology and obtaining a CCT. Applicants wishing to pursue dual accreditation in GIM and Gastroenterology will take a full part in GIM and Gastroenterology "on-call" rotas, equivalent to 50% of the WTE ST3+ posts. However, it is recognised that applicants may wish to pursue single specialty training in Gastroenterology, in which case the clinical training will only be in Gastroenterology. The clinical training in inpatient and outpatient gastroenterology, endoscopy, hepatology or nutrition will be tailored to the research and clinical interests of the successful applicant, but will not account for more than 50% of their weekly timetable. Clinical placements will be made according to the educational needs of the individual trainee to Nottingham (QMC), Derby or Mansfield as explained above.The Clinical Lecturer will be responsible for day to day management of in-patients under the care of all the Consultants he/she works with. This will also involve giving consistent and planned support for other Junior Staff attached to these consultants. All trainees are expected to attend the monthly training days arranged by the Gastroenterology training programme. They will be also be expected to attend the three Trent Region teaching days (at Nottingham, Sheffield or Leicester and will be encouraged to attend other national or international conferences, if and when appropriate). The ACL is expected to take an active part in audit and other relevant clinical governance activity being undertaken as part of the training programme, to organise clinical meetings, to contribute to the management activities of the directorates and to attend appropriate committees within the hospitals; feedback and counselling session/professional review and these are seen as essential components of higher medical training. At a ‘firm’ level he/she will be responsible for supervising the day to day work of ST1-3 trainees and Foundation Doctors.The rotation will provide training according to the requirements of the Colleges and Faculties and the Postgraduate Dean's network. The Postgraduate Dean confirms that this placement and/or programme will have the required educational and Dean's approval at the time of entry in to the programme. At the local level, Royal College/Specialty tutors work with postgraduate clinical tutors in supervising training. Annual ARCP assessment of a trainee's progress will be undertaken under the overall guidance of the Specialist Education Committees. Trainees will be expected to take part in appraisal, feedback and counselling session/professional review.

Mentoring and Supervisory Arrangements for the Academic Clinical Lecturers (ACL)It is expected that most applicants for the NIHR Clinical Lecturers’ posts will already have identified an Academic Supervisor before applying for the post. Otherwise, the lead for academic training in Gastroenterology (Dr Gordon Moran: [email protected]) will support the new NIHR Clinical Lecturer in selecting an appropriate Academic Supervisor for their chosen research field. As for all Specialty Trainees, clinical training will be co-ordinated by the Clinical Training Lead in the hospital in which the Clinical Lecturer is working under the overall direction of the East Midlands (North) Training Director, Dr Aida Jawhari. All training will be organised in conjunction with the Academic Supervisor.

Assessment of Academic/Clinical Competencies and Joint Process ManagementAll Clinical Lecturers undergo a formal annual academic appraisal to monitor progress and expectations. An academic report from this is submitted to, and considered by, the joint Clinical Academic ARCP Panel which monitors progress of Specialty Trainees and Clinical Lecturers each year. Progress will also be monitored with an internal review at 2 years. In the event that an individual is unsuccessful in developing their postdoctoral research career or higher educational training within this timeframe, he/she will re-join the full-time clinical training programme to complete CCT.

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mailto:[email protected]

Nottingham Digestive Diseases Biomedical Research UnitMore information about the Nottingham Digestive Diseases Centre is available at:http://www.nottingham.ac.uk/medicine/about/nddc/index.aspxInformation on the University of Nottingham School of Medicine and on the City of Nottingham is given in the Appendices at the end of this document.

DETAILS OF PARTICIPATING HOSPITALSNOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST: QUEEN’S MEDICAL CENTRE

University Hospital (Queen’s Medical Centre) is a major teaching hospital with a total of 1272 beds and is the major accident and emergency centre for Nottingham. The hospital forms part of the Queen's Medical Centre, which also houses the Faculty of Medicine and associated academic groups, including academic gastroenterology. Greenfield Medical Library, one of the largest medical libraries in the Midlands, is also housed in Queens Medical Centre.The Gastroenterology firm consists of Consultants with varying specialist clinical and research interests, which include, intestinal infections (especially H. pylori and C. difficile infections), hepatobiliary disease, inflammatory bowel disease, neurogastroenterology, gastrointestinal endoscopy, nutrition and coeliac disease. The firm includes 8 NHS consultants, 4 Associate Professors and 5 Professors, 3 F1s, 1 F2, 4 ST1s or 2s, 4 ST3+ and one other Clinical lecturer at present (in addition to this post).The 4 ST3+ along with Lecturer(s) share the inpatient and outpatient care of patients with acute and chronic medical and gastrointestinal problems, including the provision of specialist services in inflammatory bowel disease, hepatobiliary disease, nutrition and endoscopy. There are separate rotas for acute gastroenterology and GIM to which at present SPRs contribute in the day for acute gastroenterology and out of hours for GIM.An example of the work programme is as follows:

Monday Tuesday Wednesday Thursday Fridayam 9-11 Ward work

11-1300 Research & Education

9-11 Ward work11-1300 Research & Education

OP 9-11 Ward work11-1300 Research & Education

2 hr Gastroenterology meeting

pm MDT meeting followed by Endoscopy list



OP 1400-1700 Research & Education

The NUH Digestive Diseases and Thoracic Directorate

Recent service reconfiguration has allowed the opportunity to develop a directorate with medical and surgical sub-specialities integrated along the lines of care pathways rather than historical boundaries. The new integrated directorate will allow service provision, resource utilization and operational management to be more streamlined and efficient. Managerial structure of the directorate is as follows-Clinical Director Dr Iain CameronDirectorate General Manager Ms Gail Walder Assistant General Manager Mr Richard DoaneMedical Services Manager Miss Rachael BriggsDirectorate Finance Manager Ms Candice RobertsDeputy Finance Manager Ms Gurpreet MahalDirectorate HR Manager Mrs Debbie HuntDirectorate Clinical Lead Mrs Anne Scott Matrons Sr J Barker, Sr R Patel & Dr G ElwoodClinical Heads of service leads: Gastroenterology & Nutrition– Dr Martin James

Endoscopy- Professor K Ragunath Upper GI- Simon Parsons

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Thoracic – Mr J P Duffy HPB – Mr D Gomez Colorectal – Mr C Maxwell-Armstrong

Directorate Medical StaffLuminal NHS Staff Dr K Teahon

Dr A JawhariDr T BowlingDr S Samuel

University Staff Professor J C AthertonProfessor Y R MahidaProfessor R C SpillerProfessor K RagunathDr G Moran (Associate Professor)

Hepatology NHS Staff Dr S D RyderDr M JamesDr E Wilkes

University Staff Professor Guru AithalDr I N Guha (Associate Professor)

GI/Hepatology/GIM NHS Staff Dr N LewisGI Epidemiology University Staff DR J West (Dept of Public Health)

(Associate Professor)Dr T Card (Associate Professor)

Hepato-pancreaticobiliary Surgery

NHS & University Staff Mr I J BeckinghamMr A BrooksProfessor D N LoboMr I CameroonMr D GomezMr C Macutkiewicz (Locum consultant)

Colorectal surgery NHS Staff Mr J F AbercrombieMr C Maxwell-ArmstrongMr M H RobinsonMr J P WilliamsMrs K WalterMr A Banerjea

University Staff Professor J H ScholefieldMr A Acheson (Associate Professor)

Upper GI Surgery NHS Staff Mr N T WelchMr S L ParsonsMr J Catton

Thoracic NHS Staff Mr A Martin-UcarMr J P DuffyMr A MajewskiMs E Internullo

Conditions of Service and GovernanceThe successful candidate will be offered an Honorary Contract with Nottingham University Hospitals NHS Trust under their terms and conditions. When undertaking clinical duties on this basis within the Trust, the person appointed will be expected to adhere to local policies and procedures and to take note of the standing orders and financial instructions of the Trust. Nottingham University Hospitals NHS Trust is committed to the development of Clinical Governance. The approach taken is to develop actions plans at a Directorate level. Each member of the medical staff is expected to take an active role in clinical governance activities within their Directorate and each Directorate has a Consultant nominated as Clinical Governance lead. The activities include (but are not restricted to) audit, incident reporting, review of complaints, risk management, CPD and Evidence Based Practice.

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Professional Standards The Clinical Director (Mr Anwar Zaman) is managerially responsible for all activity and personnel in the Directorate in which the appointee will work. The Medical Director, Dr Stephen Fowlie, has overall responsibility for the professional performance of clinicians, including of those holding Honorary Contracts with NUH. All clinicians are expected to comply with management arrangements in place, to follow the guidelines on practice laid down by the General Medical Council’s “Maintaining Good Medical Practice”, and to be accountable to the Trust for their actions and the quality of their work. A yearly Joint Clinical and Academic Appraisal is carried out.Information on other Trusts in which the Clinical Lecturer may undertake placements during their clinical training follow.DERBY HOSPITALS NHS FOUNDATION TRUST

The GI unit at the Royal Derby Hospital has 3 consultant hepatologists and 6 luminal gastroenterologists, in addition to 2 F1s, 2 F2s, 2 ST1/2s and 4 SPRs. Specific training opportunities in Derby include hepatology, interventional endoscopy (including laser, APC, PDT and stent insertion), endoscopic ultrasound and ERCP. Derby has a graduate entry Medical School based on the Derby City site and all members of the team take an active part in both pre-clinical and clinical teaching. We also have an active research unit with current research areas including inflammatory bowel disease, Barrett’s oesophagus, portal hypertension, celiac disease and endoscopy tumour palliation.Proposed weekly timetable: (This assumes block release for academic work.)

Monday Tuesday Wednesday Thursday Fridayam GI Clinic GI meeting

Consultant ward round

SpR ward round/MDT

Consultant WR Grand roundAdmin /Ward

pm Admin/Ward work

Endoscopy Admin/ward GI Clinic X ray meeting(1-2pm)Endoscopy

SHERWOOD FOREST HOSPITALS TRUST: THE KING'S MILL CENTREThe King's Mill Centre provides the acute medicine and outpatient services for the towns of Mansfield, Sutton in Ashfield and the surrounding population. Appointees will gain wide experience in general medicine, working in a team of 4 consultant Gastroenterologists, 1 Associate Professor 2 F1s, 2 F2s, 2 ST1/2s and 2 SPRs.

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A proposed weekly timetable is given below. (This assumes block release for academic work.)

Monday Tuesday Wednesday Thursday Fridayam Consultant

WRXRAY meeting

Admin/ ward work

SPR ward roundGrand round

Consultant WRColorectal MDT

Journal Club/Clinical casesERCP/ Endoscopy

pm Endoscopy OP Admin/ ward work/ audit and clinical governance meetings

OP Admin/ ward work

Person Specifications for Candidates Applying for an Academic Clinical Lectureship in Gastroenterology

Applicants must have all of the essential criteria listed in BOTH the academic person specification AND the appropriate clinical person specification (ST3+ depending on the level of training at entry).

The post is only open to those eligible to hold an academic National Training Number who will have maximum of 2 years and minimum of 1 year of clinical training to complete before attaining their CCT in specialty or subspecialty on 31 March 2015.

The clinical person specification can be found at: http://specialtytraining.hee.nhs.uk/files/2013/03/2014-ST3-gastroenterology-person-specification-v3.0.pdf The academic person specification for the ACL in Gastroenterology is provided below.

ACADEMIC PERSON SPECIFICATION FOR CANDIDATES APPLYING FOR A CLINICAL LECTURESHIP in GASTROENTEROLOGY AS PART OF INTEGRATED ACADEMIC TRAINING

ESSENTIAL DESIRABLE WHEN EVALUATEDELIGIBILITY Evidence of

achievement of Foundation competences or equivalent.

Must hold a higher research degree (MD, PhD or equivalent) in a relevant subject area.

Evidence of good progress in clinical training and that completion of specialty training may be accommodated either during or after the 4 year period of the NIHR CL award.

Candidate must have less than or equal to 2 years, but more than

Evidence of commitment to specialty.

Intercalated honours degree and/or additional qualifications e.g. MSc etc.

Application form

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http://specialtytraining.hee.nhs.uk/files/2013/03/2014-ST3-gastroenterology-person-specification-v3.0.pdf

http://specialtytraining.hee.nhs.uk/files/2013/03/2014-ST3-gastroenterology-person-specification-v3.0.pdf

ACADEMIC PERSON SPECIFICATION FOR CANDIDATES APPLYING FOR A CLINICAL LECTURESHIP in GASTROENTEROLOGY AS PART OF INTEGRATED ACADEMIC TRAINING

ESSENTIAL DESIRABLE WHEN EVALUATEDone year of, clinical training remaining before the award of Certificate of Completed Training (CCT).

KNOWLEDGE & ACHIEVEMENTS

Demonstration of acquisition of the level of knowledge and skills necessary for the achievement of Foundation and clinical competencies or equivalent (matched to the entry level).

Demonstration of understanding of, and commitment to, an academic career.

Demonstration of the potential for scientific independence and the ability to lead a research team.

Potential to become a leader in chosen field.

Knowledge of the centre hosting the research and how this is best placed to support the research, education and training needs.

Prizes or distinctions. Presentation of work at

national or international meetings.

Significant publications in peer reviewed journals.

Application form and selection centre

EDUCATIONAL & PERSONAL ASPECTS

Demonstration of understanding and commitment to academic career.

Indication of medium and long-term career goals.

Demonstration of educational reasons for applying for Clinical Lectureship Programme.

Application form

PROFESSIONAL SKILLS

Evidence of team working skills.

Evidence of leadership potential.


LEGAL Satisfactory Enhanced disclosure from the Disclosure and Barring Service.

GMC registration with a licence to practise.

Because of the nature of the work, this post is exempted from the provisions of Section 4 (2) of the Rehabilitation of Offenders Act 1974 by virtue of the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975.

Applicants are, therefore, not entitled to withhold information about convictions, which for other purposes are “spent” under the provisions of the Act, and in the event of employment any failure to disclose such convictions could result in dismissal or disciplinary action by the University. Any information given will be strictly confidential and will be considered only in relation to an application for

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positions to which the Order applies. This post cannot be taken up until satisfactory enhanced disclosure has been received. If once employed, an employee receives a conviction, they are required to inform the University and the Trust.

Due to the requirements of the UK Border and Immigration Agency, applicants who are not UK or EEA nationals and whose immigration status entitles them to work without restriction in the UK will be considered on an equal basis with UK and EEA nationals. Please visit http://www.ukba.homeoffice.gov.uk/ for more information.

Further information for applicants to the ACL post in GASTROENTEROLOGYCandidates are strongly encouraged to make informal enquiries and should contact Dr Moran in the first instance: Dr Gordon Moran, Academic Programme DirectorClinical Associate Professor and Honorary Consultant Gastroenterologist, Clinical Training Lead for the Nottingham Digestive Disease Centre, NIHR Nottingham Digestive Diseases Centre, Biomedical Research Unit, D1406, West Block, Queen's Medical Centre, Nottingham NG7 2UH. Telephone: +44 (0)115 9249924 ext 70608; email: [email protected] on the Clinical Training Aspects of the Post may be addressed to: Dr Aida Jawhari, Clinical Training Programme DirectorNottingham University Hospitals QMC campus, D Floor South block, opposite endoscopyDerby Road NG72UH, Telephone 0115 9249924 ext 66292/6; e-mail: [email protected]

Guidance on Academic Clinical Lectureships is available from http://www.nihr.ac.uk/funding/cl-information-for-applicants.htm

The University’s Clinical Academic Training Programme Directors, Professor Helen Budge and Professor Simon Johnson are also able to provide advice on the training programme.see website: www.nottingham.ac.uk/go/catp

Please note that applications sent directly to these email addresses will not be considered.

Potential Applicants should also view the Appendices at the end of this document.

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http://www.nihr.ac.uk/funding/cl-information-for-applicants.htm



http://www.ukba.homeoffice.gov.uk/


Job Title: NIHR Academic Clinical Assistant Professor (ACL) in Medical Oncology

School/Department: School of Medicine - Division of Cancer and Stem Cells

Salary: £31,301 - £54,199 per annum, depending on skills and experience

Contract Status: This post will be offered on a fixed-term contract for a period of 4 years (if full-time; up to a maximum of 6 years part-time) or until award of Certificate of Completion of Training (CCT), whichever is the shorterSuccessful applicants must be in post before 31 March 2015

Hours of Work: Full-time or Part-time (minimum 0.6FTE)

Location: City Hospital Campus, Nottingham

Reporting to: Head of Academic Unit of Clinical OncologyThe University of Nottingham seeks applications for an NIHR-funded Academic Lecturer (ACL) in Medical Oncology based at the City Hospital Campus of the University of Nottingham and Nottingham University Hospitals NHS Trust. The post is offered in competition with eligible applicants in Gastroenterology. The post is designed for Academic Clinicians to allow them to continue and complete higher specialist training in Medical Oncology and combine this with postdoctoral Cancer Research. The applicants should have a record of successful research and must possess a higher degree (PhD or research MD).The Post The Post provides an excellent opportunity for somebody seeking a long term career in Academic Oncology. The Post will provide 50% clinical training and 50% research overall but time allocated to clinical training and to academic work may be annualised, i.e. taken in blocks, as appropriate to successful candidate’s clinical and research training needs. Clinical training will be tailored for the successful candidate to allow them to complete their clinical training to obtain a CCT in Medical Oncology. The post holder will join an existing research grouping either with their own research proposal or one developed in conjunction with research teams in Nottingham. The successful ACL will become a member of the well-developed Clinical Academic Training Programme in the School of Medicine, University of Nottingham (www.nottingham.ac.uk/go/catp). The programme provides support in integrated clinical academic training, with research funding applications, through networking, mentorship and with an annual research conference bursary.The post holder will join an existing research grouping either with their own research proposal or one developed in conjunction with research teams in Nottingham. During the academic component of the post, the ACL will further develop their academic skills at postdoctoral level, build on their research in Medical Oncology, undertake research, develop their own research programme and compete for external grant funding. During periods of clinical training, the successful candidate will carry the full clinical responsibilities of a Specialty Trainee on the North (Nottingham-centred) Carousel of the Health Education East Midlands (HEEM) clinical training rotation in Medical Oncology where they will work alongside clinical-track colleagues to attain their remaining competencies in their Specialty Training.

Applicants must, therefore, be eligible to hold an academic National Training Number (NTN(A)) and show evidence of academic achievement, including a higher research degree at PhD/DPhil or MD/DM level, and successful outcomes from previous clinical annual assessments (ARCPs).

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The post is open to those who are at, or within, 2 years of clinical training of attaining their CCT in specialty or subspecialty. Most benefit from the post will be obtained by those with at least 1 year of clinical training to complete. Whilst the post will be offered on a fixed term contract for a period of up to 4 years, or until award of CCT whichever is shorter, the candidate would be expected to develop plans for a post-doctoral or clinician scientist award, which may shorten the lectureship. An Honorary Specialty Registrar contract will be sought from Nottingham University Hospitals NHS Trust.Research The ACL will be expected to develop, and work within, a programme of high quality competitive research, publish in quality peer review journals and be capable of securing external funding. Research may include clinical and/or laboratory based research programmes. There is no other specific area of cancer research that is targeted for this post but it is important that the research complements existing research strengths within the University. Initial support for research will be provided to allow the successful candidate to apply for future independent research funding. The ACL would be expected further develop their track record in research and will have access to the research facilities in the School of Medicine which has excellent laboratory and clinical trials support. They will be expected to undertake research and, as part of their research portfolio, they will be expected to develop skills in research supervision through the supervision of the research component in the 3rd year of the BMedSci medical student degree. Cancer research strengths in Nottingham include, among others, basic cancer biology, mechanisms of blood vessel growth and permeability in cancers, drug development, tumour immunology, DNA repair, pre-clinical models, imaging, early diagnosis and palliative care. The research attracts external grant funding from MRC, BBSRC, CRUK, Wellcome Trust amongst others. There is very active clinical trials programme with over 50 cancer clinical trials open ranging from Phase I-III trials.Cancer research strengths in Nottingham include, among others, basic cancer biology, drug development, tumour immunology, DNA repair, pre-clinical models, imaging, early diagnosis and palliative care. The research attracts external grant funding from MRC, BBSRC, CRUK, Wellcome Trust amongst others. There is very active clinical trials programme with over 50 cancer clinical trials open ranging from Phase I-III trials. More details of the research in the Division of Cancer and Stem Cells are given below.Information about research in the School and the Division can also be found at:

http://www.nottingham.ac.uk/medicine/index.aspx and http://www.nottingham.ac.uk/medicine/about/cancerandstemcells/index.aspx respectively.

Teaching Teaching is a core generic academic skill and the ACL will be expected to take an active role in contributing teaching both undergraduate and graduate students on the University’s Medical Course and on postgraduate MSc courses.The Academic Unit of Clinical Oncology runs 2 very successful MSc research courses. The MSc in Medical Oncology course provides training for speciality registrars in the East Midlands, and basic scientists from across the world. The MSc in Cancer Immunology is one of the few postgraduate cancer immunology courses in the country. The Nottingham Medical Course includes special study clinical attachments in Oncology. The BMedSci is an integral part of the undergraduate five-year medical course and all students pursue a research project learning to appraise scientific papers and research methodology. The unit has several BMedSci projects running every year.

Clinical DutiesThis post combines protected time for post-doctoral cancer research with clinical training in Medical Oncology. The Academic Clinical Lecturer will have responsibility of clinical care at ‘Specialty Trainee’ level within the Nottingham University Hospitals NHS Trust, Department of Clinical Oncology. As part of their clinical training, the post holder will rotate through different site specialist teams as required by

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their clinical training needs. They will be expected to carry out the duties of a higher Specialty Trainee, providing support in clinics and on inpatient wards and to provide support for the junior staff. The Academic Clinical Lecturer will also take part in out-of-hours (on call) clinical duties as part of an on call rota and be expected to cross cover other trainees in certain instances. OUTLINE JOB PLANThe exact details of the job plan will depend on the nature of the research and the level of training of the appointee. As an example, this is Job Plan is for the ACL while working in the Melanoma / Renal cancer team. A similar, but different, Job Plan will be arranged for each part of the clinical rotation.

AM PMMON Research Outpatient ClinicTUE Research Outpatient ClinicWED Research ResearchTHU Education, Audit AdminFRI MDT. WR Research

Academic DutiesThe ACL will be able to explore their research programme with support and supervision from senior academics in the Division of Cancer and Stem Cells. The ACL will be able to access research opportunities as part of the Division of Cancer and Stem Cells and in the wider Cancer Research activity at University of Nottingham.Cancer Biology Unit The Cancer Biology Unit within the Division of Cancer & Stem Cells is a multi-disciplinary research centre working on biological basic of cancer, failure of anti-cancer drugs in early clinical trials, cancer genetics and stem cell biology. Translation of new findings on mechanisms and cancer processes into novel therapeutic approaches for cancer and other diseases are research priorities. Academic Staff of the Cancer Biology UnitProfessor David Bates, Professor of OncologyDr Anna Grabowska, Associate ProfessorDr Abdolrahman Shams-Nateri, Associate ProfessorRoya Babaei-Jadidi, Andrew Benest, Maria Machado, Research FellowsProfessor David Bates in the Head of the Cancer Biology Unit which sits within the Division of Cancer and Stem Cells (Head: Professor Poulam Patel). More information is available at:http://www.nottingham.ac.uk/research/groups/cancerbiology/index.aspxAcademic Unit of Clinical and Translational OncologyThe Academic Unit of Clinical and Translational Oncology is part of University of Nottingham’s Division of Cancer and Stem Cells, and is based predominantly in purpose built Oncology facilities at the Nottingham City Hospital Campus. There is currently 845 m2 of space consisting of eight laboratories (265 m2), including three designed for research, three isotope rooms and two tissue culture laboratories, additional rooms associated with the laboratories, data handling room and offices (359m2). http://www.nottingham.ac.uk/medicine/about/cancerandstemcells/index.aspxThere are 5 research groups, 4 laboratory groups and 1 in palliative care.Academic Staff of the Academic Unit of Clinical and Translational OncologyProfessor Poulam Patel, Professor of Clinical Oncology Professor Lindy Durrant, Professor of Cancer Immunotherapy

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Dr Andrew Wilcock, Clinical Reader in Palliative CareDr Srinvasan Madhusudan, Clinical Associate Professor in Medical OncologyDr Stewart Martin, Reader in Cancer and Radiation BiologyDr Ian Spendlove, Associate ProfessorDr Andrew Jackson, Associate ProfessorDr Judith Ramage, LecturerProfessor Poulam Patel is the Head of the Academic Unit of Clinical Oncology with overall responsibility for management and delivery of teaching and research supervision in the Oncology Department. The Unit of Academic Oncology within the Division of Cancer and Stem Cells is also headed by Professor Patel. The Dean of the School of Medicine is Professor John Atherton.Whilst a wealth of research opportunities is available, specific examples of Clinical Research include:

i) Clinical TrialsThe Academic Unit of Clinical and Translational Oncology, in Partnership with the NHS Department of Clinical Oncology and the local National Cancer Network, has a state of the art Cancer Clinical trials team. The group is a 50 person strong multidisciplinary team of research nurses and radiographers, data managers and ethic and finance managers and carries out both simple and complex clinical trials according the highest standards of Good Clinical Practice. With over 50 open clinical trials and >1000 patients entered into trials in the last 3 years we have an annual financial turnover of >£0.5M. We conduct Phase I to III trials in the majority of tumour types and the close proximity of the clinic to the laboratory facilitates sample collection for translation studies, an essential part of many new targeted therapy trials in cancer

ii) Tumour Host-Cell Interactions - Professor Poulam Patel, Dr Andrew JacksonOur research focuses on understanding how tumours suppress the immune system and devising novel ways to restore immune function. We recently identified alterations in molecular signalling pathways of dendritic cells (DC) induced by tumours and showed that these pathways can be drugged to restore appropriate immune function. We are currently investigating the clinical application of MAPK-inhibitors in manipulating DC function in cancer & the role of intracellular stress signals in modifying immune responses. A key focus of our group is the translation of our basic observations to clinical application. In this regard, we have a track-record of translation from basic laboratory research into clinical trials in patients with advanced cancer and are ideally placed to take advantage of the Clinical Cancer Centre.

iii) Immunotherapy Group - Professor Lindy Durrant, Dr. Ian Spendlove, Dr. Judith RamageThe Immunotherapy group have 2 main focus areas:.

- development of monoclonal antibodies and - cancer vaccines to novel tumour antigens.

Our access to primary human tumour tissues enables us to use this resource to develop unique antibodies/vaccines. We are currently developing antibodies/vaccines to aberrant glycolipids and glycoproteins that are uniquely expressed by tumours. This involves purification and characterisation of these reagents for immunisation and assay. We then optimise therapeutic potential of Mabs by cloning and engineering to maximize effector mechanisms including complement and cell mediated cytotoxicities. We have developed assays to investigate and validate these responses. We then have access to a range of therapeutic models in order to test anti tumour responses.Our second area of expertise is in generating regulatory immune responses within the tumour environment. Here we have models Tregs, toleragenic DC and tumour vasculature.We have a unique in vitro model of generating Tr1 regulatory T cells via the CD55 co-stimulatory pathway, identifying CD55 and its counter receptor (CD97) as key mediators in Tr1 differentiation. We have established endothelial transmigration assays to demonstrate that tumour conditioning results in the preferential recruitment of Tregs to tumours where they suppress effective immune responses. This work is carried out with both primary human T cells and therapeutic models where we are able to study T cell tumour interactions in vivo and in vitro.

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These are brought together to enable a targeted approach to the analysis of host tumour interactions with the aim of identifying novel drug targets and modes of reversing the immune-inhibitory tumour environment.

iv) Translational Radiation Biology Group- Dr Stewart MartinResearch in the TRBR group focuses upon lymphatic biology, particularly how it relates to metastatic dissemination of cancer (primarily breast cancer and melanoma), and regulation of redox homeostasis, principally the role that redox proteins play in modulating cancer cell response to therapy, both radiotherapy and chemotherapy. The acquisition of the Wellcome Trust funded cabinet irradiation facility will allow a significant expansion of this latter area and allow additional collaborative ventures to be instigated, examining molecular responses of how cells respond to ionizing radiation, how these can be modulated to increase tumour cell kill but minimising normal cell lethality, and also how radiation may be combined with novel chemotherapy agents to increase therapeutic efficacy. We have a broad range of local, national and international collaborations

v) Translational DNA Repair Group – Dr Srinivasan MadhusudanThe anti-cancer activity of many chemotherapeutic agents and ionizing radiation is directly related to their ability to induce DNA damage in tumour tissue. Cellular responses to DNA damage are complex but the ultimate fate of the cell is dictated by its ability to repair such damage; extensive unrepairable DNA damage promoting cell death and efficient DNA repair promoting cell survival. This would imply that proficient DNA repair in tumours could contribute to therapeutic resistance. Pharmacological inhibition of DNA repair may improve therapeutic response and improve patient outcomes. The main aim of our group is to develop small molecule inhibitors of Human AP endonuclease 1 (APE1) a critical protein involved in DNA Base excision repair that is involved in the repair of DNA damage induced by alkylating agents. To achieve this goa,l we have used molecular modelling, virtual screening, fluorescence based high through-put screening, DNA repair biochemical assays and cell based cytotoxicity investigations. In addition to drug discovery research, our group is focussed on developing predictive biomarkers of response to chemotherapy in gastro-intestinal cancer patients. We have developed and employed high throughput tissue microarray (TMA) based investigations focussed on DNA repair pathways to achieve this goal.

NHS DEPARTMENT OF ONCOLOGYThe Department of Clinical Oncology is part of the Cancer and Associated Specialties Directorate at the Nottingham University Hospital NHS Trust and Dr Daniel Saunders is the Head of Service for the NHS Oncology Service. The Department serves a resident population of 1.1 million and currently sees approximately 3000 new patients each year; providing a comprehensive range of non-surgical Oncology services to the East Midlands. The Academic Division of Clinical Oncology is based in the Department and, together with the whole of the Division, strives to deliver the highest standards of treatment and care to patients.The Department has 5 Medical Oncology and 10 Clinical Oncology Consultants providing site specialist care in multi-disciplinary teams. There is an established Medical Oncology Higher Specialist Training programme (3 posts) and a Clinical Oncology programme (currently 7 posts). The department has 2 F1s, 3 F2s and 3 ST1/2 trainees as part of the East Midlands Healthcare Workforce Deanery (North) training rotations. The Department has 5 NIHR Academic Clinical Fellows in Oncology.The Department has a very active Clinical Trials programme with a dedicated research team for academic, NCRN and industry lead studies as well as integral working with the NCRN research team.There is a commitment from all staff to research, development and clinical audit within the Department at a multidisciplinary level.The Department occupies a modern purpose-built block, into which it moved in 1993, having previously been sited at the former Nottingham General Hospital. We are equipped with:-

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44 in-patient beds (18 on Fraser Ward (plus a 4-bedded day case facility for chemotherapy), 18 on Gervis Pearson Ward and 8 on Bernham.

There is one room on each of Fraser and Gervis Pearson Wards for the administration of sealed or unsealed radioactive sources and a two-bedded suite on Fraser Ward for brachytherapy (selectron).There is a new expanded chemotherapy day case facility and a dedicated clinical trials area. Computer based prescribing using the Chemocare system is in place.There is a separate oncology outpatients department and oncology pharmacy located within the Oncology building. We have dietitians, physiotherapists, social workers and occupational therapists dedicated to the Oncology Unit. There is a Data Management Team with Research Chemotherapy Nurses and Research Radiographers available to support clinical research. There is a fully equipped and well staffed Radiotherapy Department. See also Appendix 2.Consultant Medical Staff:Dr Victoria Brown, Medical Oncologist – Breast Cancer, Acute OncologyDr Kate Cardale, Clinical Oncologist - Lung, Sarcoma, Dr Steve Chan, Clinical Oncologist - Breast and Gynaecological CancersDr Judy Christian, Clinical Oncologist – Head and Neck cancerDr Karen Foweraker, Clinical Oncologist - Lung and Brain TumoursDr Eleanor James, Clinical Oncologist - Hepatobiliary Cancer, Upper GI, LymphomaDr Ivo Hennig, Medical Oncologist - Sarcoma, Germ Cell Cancer, Lung Colorectal cancerDr Sarah Khan, Medical Oncologist - Breast and Lung CancersDr Pat Lawton, Clinical Oncologist - Breast Cancer and Skin CancerDr Jamie Mills, Clinical Oncologist - Colorectal and Urological CancersDr Sally Morgan, Clinical Oncologist - Lung, GI and Thyroid CancersProfessor Poulam Patel, Medical Oncologist – Renal cancer and melanomaDr Vanessa Potter, Medical Oncologist – Colorectal cancer and Lung cancerDr M Sokal, Clinical Oncologist - GU, Sarcomas and Paediatric CancersDr Srinivasan Madhusudan, Medical Oncologist - hepatobiliary cancer, upper GI cancer. Dr Daniel Saunders, Clinical Oncologist - Paediatric RT, GU CancersDr S Sundar, Clinical Oncologist - GU, Gynaecological CancersJunior Medical Staff10 StRs (3 Medical Oncology, 7 Clinical Oncology), 2 current ACFs ST3, ST4

Mentoring and Supervisory Arrangements for the Academic Clinical Lecturers (ACL)It is expected that most applicants for the NIHR Clinical Lecturers’ posts will already have identified an Academic Supervisor before applying for the post. Otherwise, the lead for academic training in Medical Oncology (Professor Poulam Patel: [email protected]) will support the new NIHR Clinical Lecturer in selecting an appropriate Academic Supervisor for their chosen research field. As for all Specialty Trainees, clinical training will be co-ordinated by the Clinical Training Lead in the hospital in which the Clinical Lecturer is working under the overall direction of the East Midlands (North) Training Director, Dr Sarah Khan. All training will be organised in conjunction with the Academic Supervisor.Assessment of Academic/Clinical Competencies and Joint Process ManagementThe successful candidate will be responsible to the Head of the Academic Unit of Clinical Oncology through whom they are accountable to the Dean of the School of Medicine and the Dean of the Faculty of Medicine and Health Sciences at the University of Nottingham. Clinical training will fall under the auspices of the East Midlands Local Education Training Board (LETB).All Clinical Lecturers undergo a formal annual academic appraisal to monitor progress and expectations. An academic report from this is submitted to, and considered by, the joint Clinical Academic ARCP Panel which monitors progress of Specialty Trainees and Clinical Lecturers each year. In the event that an individual is unsuccessful in developing their postdoctoral research career or higher educational training within this timeframe, he/she will re-join the full-time clinical training programme to complete CCT.

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Person Specifications for Candidates Applying for an Academic Clinical Lectureship in Medical Oncology

Applicants must have all of the essential criteria listed in BOTH the academic person specification AND the appropriate clinical person specification (ST3+ depending on the level of training at entry).

The post is only open to those eligible to hold an academic National Training Number who will have maximum of 2 years and minimum of 1 year of clinical training to complete before attaining their CCT in specialty or subspecialty on 31 March 2015.

The clinical person specification can be found at: http://specialtytraining.hee.nhs.uk/files/2013/03/2015-PS-Medical-Oncology-ST3-1-0.pdf The academic person specification for the ACL in Medical Oncology is provided below.

ACADEMIC PERSON SPECIFICATION FOR CANDIDATES APPLYING FOR A CLINICAL LECTURESHIP in MEDICAL ONCOLOGY AS PART OF INTEGRATED ACADEMIC TRAINING

ESSENTIAL DESIRABLE WHEN EVALUATEDELIGIBILITY Evidence of

achievement of Foundation competences or equivalent.

Must hold a higher research degree (MD, PhD or equivalent) in a relevant subject area.

Evidence of good progress in clinical training and that completion of specialty training may be accommodated either during or after the 4 year period of the NIHR CL award.

Candidate must have less than or equal to 2 years, but more than one year of, clinical training remaining before the award of Certificate of Completed Training (CCT).

Evidence of commitment to specialty.

Intercalated honours degree and/or additional qualifications e.g. MSc etc.

Application form

KNOWLEDGE & ACHIEVEMENTS

Demonstration of acquisition of the level of knowledge and skills necessary for the achievement of Foundation and clinical competencies or equivalent (matched to the entry level).

Demonstration of understanding of, and commitment to, an academic career.

Knowledge of the centre hosting the research and how this is best placed to support the research, education and training needs.

Prizes or distinctions. Presentation of work at

national or international meetings.

Significant publications in peer reviewed


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ACADEMIC PERSON SPECIFICATION FOR CANDIDATES APPLYING FOR A CLINICAL LECTURESHIP in MEDICAL ONCOLOGY AS PART OF INTEGRATED ACADEMIC TRAINING

ESSENTIAL DESIRABLE WHEN EVALUATED Demonstration of the

potential for scientific independence and the ability to lead a research team.

Potential to become a leader in chosen field.

journals.

EDUCATIONAL & PERSONAL ASPECTS

Demonstration of understanding and commitment to academic career.

Indication of medium and long-term career goals.

Demonstration of educational reasons for applying for Clinical Lectureship Programme.

Application form

PROFESSIONAL SKILLS

Evidence of team working skills.

Evidence of leadership potential.


LEGAL Satisfactory Enhanced disclosure from the Disclosure and Barring Service.

GMC registration with a licence to practise.

Because of the nature of the work, this post is exempted from the provisions of Section 4 (2) of the Rehabilitation of Offenders Act 1974 by virtue of the Rehabilitation of Offenders Act 1974 (Exceptions) Order 1975. Applicants are, therefore, not entitled to withhold information about convictions, which for other purposes are “spent” under the provisions of the Act, and in the event of employment any failure to disclose such convictions could result in dismissal or disciplinary action by the University. Any information given will be strictly confidential and will be considered only in relation to an application for positions to which the Order applies. This post cannot be taken up until satisfactory enhanced disclosure has been received. If once employed, an employee receives a conviction, they are required to inform the University and the Trust.

Due to the requirements of the UK Border and Immigration Agency, applicants who are not UK or EEA nationals and whose immigration status entitles them to work without restriction in the UK will be considered on an equal basis with UK and EEA nationals. Please visit http://www.ukba.homeoffice.gov.uk/ for more information.

Further information for applicants to the ACL post in MEDICAL ONCOLOGYCandidates are strongly encouraged to make informal enquiries and should contact Professor Patel in the first instance: Academic Programme Director: Professor Poulam Patel ([email protected])Information on the Clinical Training Aspects of the Post may be addressed to: Clinical Training Programme Director: Dr Sarah Khan ([email protected])

Guidance on Academic Clinical Lectureships is available from http://www.nihr.ac.uk/funding/cl-information-for-applicants.htm

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http://www.ukba.homeoffice.gov.uk/

The University’s Clinical Academic Training Programme Directors, Professor Helen Budge and Professor Simon Johnson are also able to provide advice on the training programme.see website: www.nottingham.ac.uk/go/catp

Please note that applications sent directly to these email addresses will not be considered.

Potential Applicants should also view the Appendices at the end of this document.

Appendix 1The University of NottinghamThe University of Nottingham is a global-leading, research-intensive university with campuses in the UK, Malaysia and China. Our reputation for world-class research has yielded major scientific breakthroughs such as Nobel-winning MRI techniques, drug discovery, food technologies and engineering solutions for future economic, social and cultural progress.Already ranked among the UK’s elite universities and global polls for research excellence, our reputation for world-class research has been further enhanced with the 2008 results of the Research Assessment Exercise (RAE). In addition to scoring highly in quality rankings covering major disciplines in science, engineering, the social sciences, medicine, business and the arts, it is Nottingham’s increase in research power rankings which demonstrate the impressive volume of excellent research which is carried out. We are now ranked in the Top 7 of all British universities and are one of only two institutions to move into the UK Top 10 since 2001 – an increase of seven places, making us the highest mover of any university.Following the UK’s Research Assessment Exercise (RAE) results, 90% of all research at Nottingham has been classified of an ‘international standard’ and 60% as ‘world-leading’ or ‘internationally excellent’.The main University campus is set beside a lake, in an extensive belt of woodland, parks and playing fields. The 330 acre University Park Campus is the focus of life for more than 32,000 students and houses the majority of the University’s academic schools and many of the central Services. The Jubilee campus is situated 2 miles away from the University Park, and provides extra capacity. The University Medical School is situated next to the University Park. Together with the University Hospital, it forms the Queen’s Medical Centre (QMC).University of Nottingham Medical SchoolNottingham has a strong reputation for both clinical medicine and teaching. As one of the most popular medical schools in the country, it is able to select excellent students and produce and attract good junior doctors. The School of Medicine was formed following Faculty reconfiguration on August 1st 2013. The new School of Medicine comprises the Divisions of Cancer and Stem Cell, Child Health, Obstetrics and Gynaecology; Clinical Neuroscience; Epidemiology and Public Health; Primary Care; Psychiatry and Applied Psychology; Rehabilitation and Ageing; Medical Sciences and Graduate Entry Medicine; Respiratory Medicine; Rheumatology, Orthopaedics and Dermatology and the Nottingham Digestive Diseases Centre. The School also hosts the Medical Education Centre, the Centre for Interprofessional Education and Learning, the Clinical Research Facility, the Clinical Skills Centre, NIHR design Service East Midlands, Nottingham Clinical Trials Unit, PRIMIS and Medical Imaging Unit.The new School of Medicine brings together in one School staff undertaking research for the benefit of the health of patients. It includes all primary care and hospital-based medical and surgical disciplines, principally in the Queen’s Medical Centre and City Hospital Nottingham Campuses, Royal Derby Hospitals NHS Foundation Trust and also at the University’s main campus and at the King’s Meadow and Jubilee Campuses. Most of our School’s Senior Researchers and Teachers are also clinicians who dedicate 50% of their time to patient care within the Nottingham University Hospitals NHS Trust & Royal Derby Hospitals NHS Trust. This close juxtaposition brings cutting-edge clinical care to our patients and clinical relevance to our research and teaching. We are closely integrated with our full time NHS clinical colleagues, many of whom are themselves leaders in research and teaching and who work closely with the University and this increases the mutual benefit from integration between the University and NHS.

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Mission:Our mission is to improve human health and quality of life locally, nationally and internationally through outstanding education, research and patient care.

Priorities:1. Teaching and learning, particularly training tomorrow’s doctors and teaching specialised

postgraduates 2. Research and research training: We will perform and support the highest quality “big”

research which impacts on human health and disease 3. Partnership with the NHS and other healthcare providers 4. Visibility and profile of the School of Medicine: We will do what we do better, and we will

tell others about itEthos and principles:

1. Having people and patients at the heart of all we do: our teaching and learning, our research and our patient care

2. Contribution within the School of Medicine and to society beyond our immediate roles; helpfulness and service

3. Openness and fairness, with particular emphasis on communication (both internal and external) and on equality and diversity among students and staff

4. Personal and group responsibility for all aspects of our work, within a culture of opportunity and reward

Our research spans 11 major themes, ranging from cancer to vascular medicine. We work closely with industry and the NHS. Our world-leading research ranges from basic and translational science through to clinical trials, epidemiology, and health services research. Our clear theme is improving human health, underpinning a vibrant postgraduate research training programme leading to PhD or DM. Many of our academics are clinicians, using their expertise to provide cutting edge specialised treatment to NHS patients; reflecting our ethos that patients are at the heart of all we do.Our major research themes are in Cancer and Stem Cells; Child Health, Obstetrics & Gynaecology; Clinical Neurosciences; Digestive Diseases; Epidemiology and Public Health; Mental Health; Musculoskeletal and Dermatology; Primary Care; Rehabilitation and Ageing; Respiratory Medicine and Vascular and Renal Medicine. The School of Medicine trains tomorrow’s doctors on a vibrant undergraduate medical course with a unique intercalated BMedSci, as well in a specialised graduate-entry programme built around clinical problem solving. We teach medicine and related disciplines at both undergraduate and postgraduate level. We have a dedicated clinical academic training programme and are committed to training PhD and doctoral research students and to supporting postdoctoral clinicians and scientists in their research. Professor John Atherton is Dean of the School of Medicine.For further information, please see our website http://www.nottingham.ac.uk/medicineNottinghamCentral within the East Midlands, Nottingham is a vibrant and prosperous city with something to offer everyone. It is one of the UK’s leading retail centres and has a huge variety of restaurants, bars and nightclubs which attract people from all over the UK. Culturally, it has good theatres, an arena which attracts both national and international performers and a range of historical interests relating to subjects such as the lace industry, Lord Byron and DH Lawrence. Nottingham is also known for sport, being the home of Trent Bridge Cricket Ground, Nottingham Forest and Notts County Football Clubs, the National Water Sports Centre and the Nottingham Tennis Centre. There is a good network of roads with easy access to the M1 and the A1, a fast frequent rail service to London and other major cities. Nottingham East Midlands Airport is only eighteen miles away.

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The city is set within a county of outstanding natural beauty which includes Sherwood Forest, Wollaton Park, lively market towns and wonderful historic buildings. Housing is relatively inexpensive and, in addition to the two Universities, there are excellent schools and colleges available.To find out more about Nottingham, use the following links:Nottingham County Council – Tourism http://www.experiencenottinghamshire.com/ University of Nottingham http://www.nottingham.ac.uk Zoopla (Guide to local properties) http://www.zoopla.co.uk/My Nottingham http://www.nottinghamcity.gov.uk/article/22779/Homepage(information on schools, term dates, school transport etc.)

Faculty of Medicine and Health Sciences, University of Nottingham Comprising of four schools (School of Health Sciences, School of Life Sciences, School of Medicine and the School of Veterinary Medicine and Science) we undertake research across the full range of health and basic sciences. Overall we teach around 6,000 undergraduate and 900 postgraduate taught students, with our courses being recognised for their innovative and exemplary teaching. Our wide ranging research covers areas from basic sciences to clinical translational research.VisionOur vision is to deliver world leading research and inspirational teaching for tomorrow’s scientists, doctors, nurses, midwives, physiotherapists and veterinarians.We will achieve this via our:

excellent links with industry and the NHS talented people – working and learning in a vibrant and supportive academic community commitment to inspirational teaching outstanding environment and facilities advanced research facilities and associated expertise to underpin cutting-edge research

TeachingOur teaching strategy is to develop graduates who have a thorough grounding in their subject of study, are aware of research, have a critical approach to knowledge, can study independently and have the skills and attributes to be successful in employment. We are particularly keen to ensure that our students have a well-balanced programme of lectures, small group teaching, tutorials and seminars. Laboratory and practical work are intrinsic parts of our undergraduate degrees and are highly valued and enjoyed by our students.ResearchOur wide ranging research covers areas from basic sciences to clinical translational research in which we currently supervise 800 postgraduate research students and undertake research of £43 million per annum. The Faculty provides advanced research facilities and associated expertise to underpin cutting-edge research. These include next generation high throughput gene sequencing and bioinformatics support, high content screening for drug discovery, and a wide range of imaging modalities such as MRI and PET CTs, for human and advanced animal research. The dedicated Clinical Trials Unit and Clinical Research Facility are funded in partnership with Nottingham University Hospitals NHS Trust. The Faculty’s research platforms make important contributions in four of the University’s Research and Knowledge Transfer Strategic Priority Areas:

• Biomedical Imaging • Clinical Translational Research • Drug Discovery

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• Global Food Security

NHS PartnershipsThe work we do depends on strong and effective partnerships with organisations in the East Midlands. In establishing the new Faculty of Medicine and Health Sciences we aim to make our partnerships with the NHS even stronger so that our collective research and education activities deliver the greatest benefits for patients and the public.Key Facts Around 1,700 faculty staff including 1,000 academics • Over 5,000 students including 3,652 undergraduates (7% international) • 818 postgraduate taught masters students (22% international) • 810 research students • Total research portfolio in excess of £140 million • Attracted £37.3 million in new awards in 2012-13 • 328 live research projects (2012-13)

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Appendix 2Nottingham and the Nottingham University Hospitals NHS Trust

NottinghamCentral within the East Midlands, Nottingham is a vibrant and prosperous city with something to offer everyone. It is one of the UK’s leading retail centres, has a huge variety of restaurants, bars and nightclubs which attract people from all over the UK. Culturally, it has good theatres, an arena which attracts both national and international performers and a range of historical interests relating to subjects such as the lace industry, Lord Byron and DH Lawrence. Nottingham is also known for sport, being the home of Trent Bridge Cricket Ground, Nottingham Forest and Notts County Football Clubs, the National Water Sports Centre and the Nottingham Tennis Centre. There is a good network of roads with easy access to the M1 and the A1, the rail service to London and other major cities is frequent and Nottingham East Midlands Airport is only eighteen miles away.

The city is set within a county of outstanding natural beauty that includes Sherwood Forest, Wollaton Park, lively market towns and wonderful historic buildings. Housing is relatively inexpensive and, in addition to the two Universities, there are excellent schools and colleges available.

To find out more about Nottingham, use the following links:Nottingham County Council – Tourism http://www.experiencenottinghamshire.com/ University of Nottingham http://www.nottingham.ac.ukZoopla (Guide to local properties) http://www.zoopla.co.uk/

My Nottingham (information on schools, term dates, school transport etc.)http://www.nottinghamcity.gov.uk/index.aspx?articleid=8524

Nottingham University Hospitals NHS TrustThe Nottingham University Hospitals NHS Trust is one of the largest hospital Trusts in the UK with an annual budget of more than £500 million, a total of 2,200 hospital beds across both campuses and over 11,500 staff. NUH is a major teaching Trust, enjoying close links with the region’s Universities and attracting and developing the highest calibre of staff. The work carried out at NUH has led to a reputation for excellence and is making a very real difference to people’s lives. NUH is also a cancer centre – a major element of the Mid-Trent Cancer Network.

The Trust works in close association with the University of Nottingham and the University of Derby. There are very strong links with nursing and midwifery training, which is part of the University of Nottingham Faculty of Medicine and Health Sciences, and with the locally-based Schools of Physiotherapy, Radiology and Radiotherapy.

The following two sections describe the services and facilities currently at the two campuses. However, there are ongoing discussions about the future development and location of clinical services, as a result of which some services or parts of services may relocate to the other campus.

1. City Hospital CampusThe City Hospital Campus offers a wide range of clinical services to the local population of greater Nottingham, plus a much larger population in such specialties as plastic surgery and burns, cardio-thoracic surgery, cancer, renal, breast services, clinical genetics and neonatology.

There is no Accident and Emergency department on the campus, although the hospital does take medical and surgical emergency patients referred by GPs or from other acute hospitals.

The Nottingham City Hospital campus has a long association with the city of Nottingham. It first opened in 1903 and the buildings are a mixture of old and new, although services have recently benefited from huge investment in improving the facilities for patients. These developments include the purpose-built Endoscopy Centre, Nottingham Breast Institute, Nottingham Urology Centre, Trent Cardiac Centre, Short Stay Unit, Centre for Clinical Haematology and PET scanner. There are also new staff residences on site.

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http://www.nottingham.ac.uk/

Research interests at the City campus include oncology, respiratory medicine, clinical haematology, rheumatology, diabetes/endocrinology, stroke medicine, urology, breast cancer and mineral metabolism. Professors in the following specialities are based on this site - Surgical Science, Respiratory Medicine, Microbial Diseases, Obstetrics and Gynaecology, Oncology, Medical Genetics and Stroke Medicine. In addition, there are academic departments of Haematology, Rheumatology, Continuing Care and Anaesthetics.

City Hospital is home to training centres in breast screening techniques and cardiac surgery and the Trust is a Cancer Centre, forming part of the Mid-Trent Cancer Network.

The City Hospital campus has a variety of facilities for the use of patients, visitors and staff. There is a restaurant, coffee bars selling hot and cold snacks and hospital shops.

The Nottingham City Hospital Campus of NHS Trust is a major teaching hospital with a total of 1070 beds. It is one of the campuses of the University of Nottingham with academic units in Respiratory Medicine, Haematology, Medical Oncology, Stroke Medicine, Surgery, Obstetrics and Gynaecology.In 1999 the Clinical Sciences Building (CSB), a £6M investment, was opened on the City Hospital site. This was a joint initiative by the NHS and the University of Nottingham to integrate and develop the academic presence within the City Hospital. The Division of Respiratory Medicine at Nottingham City Hospital is based in the Centre for Respiratory Research within the Clinical Sciences Building, which provides excellent, modern accommodation, teaching and laboratory facilities for undergraduate students and postgraduate work. The CSB has been expanded with a £4M extension to house the epidemiology group and Tobacco Control Centre.

Excellent facilities for cell and molecular biology research can be found in the Clinical Sciences Building. The top floor contains 40-50 lab based researchers from 5 groups (Respiratory Medicine/ Haematology/ Tumour Immunology/ Rheumatology/ Infectious Diseases0 working in a suite of state of the art laboratories with multi-user shared space and individual groups laboratories. Excellent facilities are available for cell culture and many aspects of cell and molecular biology including FACS scanning, PCR (including real time), GM work, isotope studies, gene sequencing etc. Nottingham University also has several technology platforms in genomics/proteomics/metabolomics allowing easy access to these technologies and transgenic facilities.

There are several new builds as part of the BRU including lung function and a research out-patient facility. There are excellent bronchoscopy facilities on the City Hospital site and the new BRU has one fully funded research bronchoscopy list.

2. Queen’s Medical Centre CampusAs well as the hospital, the QMC building, which opened in 1978, also houses the University of Nottingham Medical School and School of Health Sciences (incl. Nursing and Midwifery).

Clinical services provided within QMC include a very substantial emergency workload, particularly in medical admissions. Within the Medical Division services include the Emergency Department, Medicine, (including Cardiovascular, Respiratory, Gastroenterology, Diabetes and Endocrinology, Haematology, Rheumatology, Immunology, Palliative Care,) Dermatology, Intensive Care and Health Care of the Elderly. Within the Surgical Division services include Surgery, (including Vascular, Colorectal and Hepato pancreatic biliary,) ENT, Ophthalmology, Maxillofacial, Trauma & Orthopaedics, (including Spinal,) and Neurosciences. Within the Family Health Division, services include Obstetrics and Fetomaternal Medicine, Gynaecology, (including Fertility Services), Child Health (including Neonatology and Paediatric Surgery) and Occupational Health.

The QMC site has constantly developed the services it provides to enable it to meet the needs of its patients both now and for the future. Queen’s has the only Emergency Department for the city. In 2008, the new Nottingham NHS Treatment Centre opened on the QMC campus. The treatment centre is managed by an independent sector provider.

There are a number of facilities provided in QMC, including a Newsagent, Coffee shop/Sandwich bar, Clothes shop, Bank (National Westminster, open daily from 10.30 – 3.30pm) and a Pharmacy shop.

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There is a large dining area, roof garden and an active Doctors’ Mess with kitchen, PCs with Internet access, sitting room, billiard tables, and television.

Conditions of Service and GovernanceThe successful candidate will be offered an Honorary Contract with the Nottingham University Hospitals NHS Trust under the terms and conditions. When undertaking clinical duties on this basis within the Trust, the person appointed will be expected to adhere to local policies and procedures and to take note of the standing orders and financial instructions of the Trust. Nottingham University Hospitals NHS Trust is committed to the development of Clinical Governance. The approach taken is to develop actions plans at a directorate level. Each member of the medical staff is expected to take an active role in clinical governance activities within their directorate and each directorate has a Consultant nominated as Clinical Governance lead. The activities include (but are not restricted to) audit, incident reporting, review of complaints, risk management, CPD and Evidence Based Practice.

Professional Standards The Clinical Director is managerially responsible for all activity and personnel in the directorate in which the appointee will work. The Medical Director, Dr Stephen Fowlie, has overall responsibility for the professional performance of clinicians, including of those holding Honorary Contracts with NUH. All clinicians are expected to comply with management arrangements in place, to follow the guidelines on practice laid down by the General Medical Council’s “Maintaining Good Medical Practice”, and to be accountable to the Trust for their actions and the quality of their work. A yearly Joint Clinical and Academic Appraisal is carried out.

Postgraduate Facilities Nottingham University Hospitals NHS Trust fully supports and recognises the importance of continuing professional development for Consultants and career-grade staff. The facilities available to support this include two large purpose-built Postgraduate Centres. The Trust encourages consultants to participate actively in Continuing Medical Education activities both within the Trust and externally and the provision of study leave is managed by a Trust Study Leave Committee administered within the Postgraduate Centres.

The Postgraduate Centre at the City Campus provides an excellent educational environment for multidisciplinary conferences and seminars, postgraduate medical education and continuing medical education. It also provides a base for the Nottingham Vocational Training Scheme for General Practice, as well as teaching facilities and common room for undergraduate students of Nottingham University Medical School and a brand new Clinical Skills Centre.

The Postgraduate Centre at Queen’s Medical Centre Campus contains eleven meeting rooms of varying sizes and audio-visual equipment including video-conferencing.

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research interests and disciplines available at · web viewprofessor guru aithal, co-chairs...

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