research based, people driven

LEO PharmaECENA network visit, June 20, 2006

Lykke Have, Environmental Manager

2

research based, people driven

Introducing LEO Pharma Who we are today

What we value

What we look like

What we generate

What we produce & sell

3

research based, people driven

LEO today Established in 1908 in Denmark

More than 3,000 employees based in 40 countries

Headquarters in Ballerup, Denmark

Offices and affiliates in 25 countries

Areas of expertise are dermatology, coagulation, nephrology, inflammation, and immunology

Products sold in 90 countries

Group profit before tax 337 MEUR (2005)

4

research based, people driven

The LEO Vision 2010 LEO is the global, pharmaceutical leader in

dermatology based on innovative and efficacious products and associated services

Critical Care is firmly established and the Critical Care portfolio is extended with at least one new brand

5

research based, people driven

LEO management structure

Ernst LundingPresident, CEO

Poul RasmussenExecutive Vice PresidentResearch & Development

Jens Bo OlesenExecutive Vice President

Sales & Marketing

John MehlbyeExecutive Vice PresidentPlants & Manufacturing

Gitte P. AaboExecutive Vice President

Finance & IT

6

research based, people driven

LEO functions

Research & Development R&D develops drugs and New Chemical Entities

(NCE) that alleviate or cure diseases

More than 550 scientists and researchers work in R&D to fulfill these goals

We take the drugs all the way – from organic chemistry, isolation of compounds from microbial and biological material to registration

A substantial part of our research focuses on: Dermatology

Critical Care

We investigate and manage licensing activities and agreements

7

research based, people driven

LEO functions

Plants & Manufacturing More than 900 employees Five state-of-the-art

production plants situated in Denmark, France and Ireland

We are committed to customer service, efficient economic production and specified quality

We comply with all statutory requirements of

GMP Environmental protection Safety

Our production areas and equipment are documented, serviced and improved by project teams and a skilled maintenance staff

Active substance production expertise Advanced organic chemical synthesis Fermentation Extraction of tissues Advanced purification techniques Synthesis of semi-synthetic penicillins

Finished formulations & preparation production expertise

Pre-filled syringes Injectors Vials Ampoules Bottle pack eye drops Tubes Tablets Capsules, hard & soft Solutions - suspensions Lotions - mixtures Drops - eardrops Intertulle

8

research based, people driven

LEO functions

Sales & Marketing 1,000 employees in S&M worldwide, including approx. 580

sales representatives in Europe and 210 in the rest of the world

We launch, market and sell the products stemming from our research and development

We leverage our strong presence in the European home market into a platform for global expansion

We market our products in 90 countries and have affiliates and sales offices in more than 22 countries

We focus on two key areas: Dermatology Critical Care

We monitor and optimise according to market conditions allowing for a flexible approach to marketing

9

research based, people driven

Major LEO products

Dermatology Critical Care Local brands

Daivobet®/

Dovobet®/

Taclonex®

innohep® Selexid®

Daivonex®/

Dovonex®

One-Alpha® Burinex®

Fucidin®

Fucicort®

Fucidin® H

Fucithalmic®