renal_f_11

Upload: christopher-gilbert

Post on 05-Apr-2018

215 views

Category:

Documents


0 download

TRANSCRIPT

  • 7/31/2019 Renal_F_11

    1/32

    Renal systemFall 2011

    Department of Pathology,

    '

    Department of Pathology,SGU_F_11

  • 7/31/2019 Renal_F_11

    2/32

    Renal Slide 1

    Normal Gross imageof the Kidney

    Normal KidneyDepartment of Pathology,

    SGU_F_11

  • 7/31/2019 Renal_F_11

    3/32

    Renal Slide 2

    Department of Pathology,SGU_F_11

    Normal kidney (PAS and Silver stains)

  • 7/31/2019 Renal_F_11

    4/32

    Renal Slide 3

    -En- endothelial cellM- mesangial cellBM- basement membraneCL-capillary lumen

    Department of Pathology,SGU_F_11

    Structure of glomerulus

  • 7/31/2019 Renal_F_11

    5/32

    Renal Slide 4

    Department of Pathology,SGU_F_11

  • 7/31/2019 Renal_F_11

    6/32

    Renal Slide 5

    Department of Pathology,SGU_F_11

    -

  • 7/31/2019 Renal_F_11

    7/32

    Renal Slide 6

    Department of Pathology,SGU_F_11

    Immunofluorescence pattern in Acute Diffuse Proliferative GN

  • 7/31/2019 Renal_F_11

    8/32

    Renal Slide 7

    Department of Pathology,SGU_F_11

    EM findings in Acute Diffuse Proliferative GN

  • 7/31/2019 Renal_F_11

    9/32

    Renal Slide 8

    Department of Pathology,SGU_F_11

    g an ec ron m croscopy n ngs n ap y progress ve

  • 7/31/2019 Renal_F_11

    10/32

    Renal Slide 9

    Department of Pathology,SGU_F_11

    Immunofluorescence pattern in Anti-GBM disease

  • 7/31/2019 Renal_F_11

    11/32

    Renal Slide 10

    Department of Pathology,SGU_F_11

    Features of Minimal Change Disease

  • 7/31/2019 Renal_F_11

    12/32

    Renal Slide 11

    Department of Pathology,SGU_F_11

    EM findings in minimal change disease

  • 7/31/2019 Renal_F_11

    13/32

    Renal Slide 12

    Department of Pathology,SGU_F_11

    Focal Segmental Glomerulosclerosis

  • 7/31/2019 Renal_F_11

    14/32

    Department of Pathology,SGU_F_11

    Membranous Glomerulopathy (PAS stain)

  • 7/31/2019 Renal_F_11

    15/32

    Renal Slide 14

    Department of Pathology,SGU_F_11

    pattern in Membranous Glomerulopathy

  • 7/31/2019 Renal_F_11

    16/32

    Renal Slide 15

    Department of Pathology,SGU_F_11

    EM findings in Membranous Glomerulopathy

  • 7/31/2019 Renal_F_11

    17/32

    Renal Slide 16

    Department of Pathology,SGU_F_11

    Membranoproliferative Glomerulonephritis (MPGN)

  • 7/31/2019 Renal_F_11

    18/32

    Renal Slide 17

    Department of Pathology,SGU_F_11

    Interposition of mesangial cell processes in the GBM in MPGN

  • 7/31/2019 Renal_F_11

    19/32

    Renal Slide 18

    Department of Pathology,SGU_F_11

    Features of Type I (left) and Type II (right) MPGN on EM

  • 7/31/2019 Renal_F_11

    20/32

    Renal Slide 19

    Department of Pathology,SGU_F_11

    Mesangiproliferative glomerulonephritis (IgA nephropathy)

  • 7/31/2019 Renal_F_11

    21/32

    Renal Slide 20

    Department of Pathology,SGU_F_11

    EM findings in Alport syndrome

  • 7/31/2019 Renal_F_11

    22/32

    Renal Slide 21

    Hyaline cast Waxy castGranular cast

    Department of Pathology,SGU_F_11

  • 7/31/2019 Renal_F_11

    23/32

    Leukocyte and

    RBCs in urine sediment

    Department of Pathology,SGU_F_11

  • 7/31/2019 Renal_F_11

    24/32

    Renal Slide 23

    Horseshoe kidney

    Department of Pathology,SGU_F_11

  • 7/31/2019 Renal_F_11

    25/32

    Renal Slide 24

    Autosomal dominant polycystic kidney

    Department of Pathology,SGU_F_11

    disease

  • 7/31/2019 Renal_F_11

    26/32

    Renal Slide 25

    Department of Pathology,SGU_F_11

    Associated abnormalities in Autosomal dominant polycystic disease

  • 7/31/2019 Renal_F_11

    27/32

    Renal Slide 26

    Department of Pathology,SGU_F_11

    Autosomal Recessive Polycystic Kidney Disease

  • 7/31/2019 Renal_F_11

    28/32

    Renal Slide 27

    Department of Pathology,SGU_F_11

    Features of Acute Pyelonephritis

  • 7/31/2019 Renal_F_11

    29/32

    Renal Slide 28

    Department of Pathology,SGU_F_11

    Hydronephrosis

  • 7/31/2019 Renal_F_11

    30/32

    Renal Slide 29

    Department of Pathology,SGU_F_11

    Gross and microscopic features of renal cell carcinoma

    S

  • 7/31/2019 Renal_F_11

    31/32

    Renal Slide 30

    Department of Pathology,SGU_F_11

    Benign nephrosclerosise ea- tten ney n

    malignant hypertension

  • 7/31/2019 Renal_F_11

    32/32

    Renal Slide 31

    Department of Pathology,SGU_F_11