remodeling of skeletal structures bone tissue is constantly being torn down and built up about 10%...

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Remodeling of skeletal structures ne tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

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Page 1: Remodeling of skeletal structures Bone tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

Remodelingof skeletal structures

Bone tissue is constantlybeing torn down

and built up

About 10% of bone is replaced every year in an adult skeleton

Page 2: Remodeling of skeletal structures Bone tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

boneformation

bonereabsorption

osteoblasts osteoclasts

Page 3: Remodeling of skeletal structures Bone tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

boneformation

bonereabsorption

osteoblasts osteoclastsCalcitonin (CT)

from thyroidParathyroidhormone (PTH)

from parathyroid

Hormonal effects

Page 4: Remodeling of skeletal structures Bone tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

bone

formation

bone

reabsorption

osteoblasts osteoclasts

Age effects

Before age 25

Page 5: Remodeling of skeletal structures Bone tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

boneformation

bonereabsorption

osteoblasts osteoclasts

Age effects

Age 25-50

Page 6: Remodeling of skeletal structures Bone tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

boneformation

bonereabsorption

osteoblasts osteoclasts

Age effects

Age 50-120

Page 7: Remodeling of skeletal structures Bone tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

bone

formation

bone

reabsorption

osteoblasts osteoclasts

Stress effects

Stress increases bone density

Page 8: Remodeling of skeletal structures Bone tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

Direction of stresscan alter orientation

& size ofof osteons

Page 9: Remodeling of skeletal structures Bone tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

Increasingbone stress can

reduce or eliminateage-related bone loss

Page 10: Remodeling of skeletal structures Bone tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

Space traveldecreases stress

& increases bone loss

Page 11: Remodeling of skeletal structures Bone tissue is constantly being torn down and built up About 10% of bone is replaced every year in an adult skeleton

Too much stress . . .