reaction of acyl chloride and anhydride

8/2/2019 Reaction of Acyl Chloride and Anhydride

1/44

Reaction of acyl

chloride and anhydrideNor Awaathif Bt Mohd Ghazali Lee

D20091035070

Sharifah Maizura Kasmawati SyedHamzah

D20091035071


2/44

REACTION

INDUCTIONSET

EMPOWERING

ENHANCING

CLOSURE

STORY TELLING ON THE SPOT

ENJOYWATCHING

CROSSWORD

WIN AND

FORTUNE

MATCHTHEM

ACID

ANHYDRIDE

ACYL CHLORIDE

IUPACNAMENTRODUCTION

FUNCTIONALGROUPEACTION

WATER

ALCOHOL

PRIMARY

AMINE

INTRODUCTION

IUPACNAMEFUNCTIONALGROUP

REACTION

WATER

ALCOHOL

PRIMARY

AMINE

ACYLCHLORIDEACIDANHYDRIDE

Answer


3/44

Far away in a jungle, there live a bearnamed Acid Anhydride. She lives therewith her mother and her little brother.Her mother was a widowed.

STORY TELLING

TIME


4/44

One day, she decided to go for a walkwith her friend, Beez.. Suddenly, she

heard someone screaming..

Beez..do you hear that? she asked

curiously. Beez nodded his head.

Suspiciously, they walked forward tosee the thing that screamed justnow.


5/44

Hello..what happened to you? AcidAnhydride asked politely.

I think I am lost now

Ouh..My name is Acid Anhydride. You cancall me Ann. This is my friend, Beez.

My name is Acyl Chloride. Just call meChlo. Nice to meet both of you. Could youplease help me to figure out the way out?


6/44

Yeah..we can help you. But the dayis getting late now. Why not you juststay a night at my home first.Tomorrow we will figure out it.

After thinking for a while, Chlo willingto stay at Anns house for a night.


7/44

At home, Anns mother Mrs Carboxylic Acidserved a very delicious food. Her brother,

Water was just sitting. By that time, theystarted to know each other.

The more they talked, the more similarities

between them. Ann did show her fatherpicture to Chlo. To make a suprise, theirfather is the same person which is MrCarboxylic Acid.

How this could happen? Could you pleasehelp Chlo and Ann to clear up the messes?


8/44

Confused?? Let we arranged the

history of Chlos and Anns family.

Mr. Carboxylic Acid

Mrs. Carboxylic

Acid

Acid Anhydride Water

?

Acyl Chloride


9/44

So what is the relationship

between Ann and Chlo?

The truth is, Mr. Carboxylic Acid

was married to Miss Chlorineafter divorced with Mrs

Carboxylic Acid. Later, they gotAcyl Chloride. So they are step

brother and sister.


10/44

ON THE SPOT?

Carboxylic Acid

WaterAcyl ChlorideChlorineCarboxylic Acid

Acid Anhydride Carboxylic Acid

Rearrange the boxes so that it can become an equation of chemistry


11/44

ASPIRIN VIDEO
http://video/Aspirin%20Video.flvhttp://aspirin%20video.flv/http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://aspirin%20video.flv/http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


12/44

ACYL CHLORIDE ACID ANHYDRIDE

Polar Molecule Van Der Waals Dispersion Forces

Dipole-dipole Attraction Dipole-dipole Attraction

Van Der Waals Dispersion Forces Did not form Hydrogen Bond

Cannot form Hydrogen Bond (RO)O

ROCl -

WHAT ARE THEIR

CHARACTERISTIC?
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


13/44

What is acyl chloride???

Actually acyl chloride is the product of

carboxylic acid which is for example ethanoicacid whichat theOH group we must

replaced by the chorine atom...
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


14/44

However, it doesnt form hydrogen bonds and

acyl chlorides can not be said to dissolve in water

because they react (often violently) with it.

Is polar molecule, and also has dipole-dipole

attractions between its molecules as well as van

der Waals dispersion forces.

Like to know something

more about acyl

chloride????
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


15/44

What is acyl anhydride???

Actually acyl anhydride is the product of

two carboxcylic acid which are ethanoic acidwhich at OH group and we need to remove a

molecule of water between them....
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


16/44

Has both van der Waals dispersion forces and

dipole-dipole attractions

However it doesn't form hydrogen bonds. That

means that its boiling point isn't as high as a

carboxylic acid of similar size

More interesting facts

about acyl anhydride

are..


17/44

Have an alkyl (or aromatic) group attached to a

carbonyl function plus a labile (easily displaced)

chlorine.

Acid chlorides can be shown in text

as: ROCl
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


18/44

Acid anhydrides are formed when water is

removed from a carboxylic acid, hence the name.

Acid anhydrides can be shown in text as:

(RO)O
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


19/44

The easiest way of thinking

about the names is to see the

relationship with thecorresponding carboxylic acid

Carboxylic Acid

Name

Acyl Chloride Name Acyl Chloride

Formula

Ethanoic Acid Ethanoyl Chloride CH3COCl

Propanoic Acid Propanoyl Chloride CH3CH2COCl

Butanoic Acid Butanoyl Chloride CH3CH2CH2COCl
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


20/44

Need some exmple??

Here we go.

1. Said that we have something substituted into

the hydrocarbon chain2. Then the carbon in the -COCl group counts

as the number 1 carbon.

3. So the name is 2-methylbutanoyl chloride


21/44

Try something special by naming it

with unique name

1. Take the name of the parent acid, and replace

the word "acid" by "anhydride".

2. "Anhydride" simply means "without water".3. So . . . ethanoic acid forms ethanoic anhydride(

propanoic acid forms propanoic anhydride,

and so on).


22/44

CHCOCl + HO CHCOOH + HCl

What will happens when acyl

chloride reacts with water????

The products is..


23/44

CHCOCl + CHCHOH

CHCOOCHCH + HCl
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


24/44

Who can guess????...What is the

product when acyl chloride reacts

with primary amine????

CHCOCl + 2CHNH

CHCONHCH + CHNH+Cl
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


25/44


26/44

The product when acyl

anhydride reacts with

alcohol is

(CHCO)O + CHCHOH 2CHCOOH
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


27/44

Think.think. Think

The product when acyl

anhydride reacts withprimary amine is..
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


28/44

A C Y L A N H E D I R O L H C L Y C A D

S H A S P I R I N F E V E R C I L I N K

A C A R B O X Y L I C A C I D P Y X H R

G H G E R R S A D H G Y C A T L Z Y Y I

P O Q T Y E U F A V Q Y P J O Z X V D V

O C U S F S B J M J P U F H T H G I R B

N O Z E J T U B E C H L O R I N Z D I T

I L F U Z I T R E Q J C K X F D H X D R

F A Z E T H A N O Y L C H L O R I D E O

I T K C K H N Y P A P J E T H A N O S U

C E A C N M O N F D Q P O L A R X K Z B

B U T A N O I C A N H Y D R I D E I I L

A V R U V Z C Y U N J V T E X R I K B E

T D Z S X C A S I R U W Q V S T R I V S

I B V R D E C R N Z S C X O Z E B V B T

O C T E T S I C O O H C L S M I K H K R

N D C O H P D C S M L O V E P O N C O U

E S T E S M S N S E L I H P O E L C U N

D S I A I A C I D G A S E O U S A D I C

G L O B A L W A R M I N G W W S H D A T
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


29/44

Lets Brainwash Your Mind!!Just find all the answers for all the questionsbelow in the crossword puzzle provided. It canbe diagonal, backward, straight, vertical,horizontal and etc. Good Luck!

1. __________ is more reactive compared to anester and an amide.2. One of carboxylic acid derivatives.3. What product will be produced between thereaction of salicyclic acid and aceticanhydride?
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


30/44

4. Name of the structure

5. An acyl chloride like ________ is a colorlessfuming liquid.

6. Acyl chlorides can be used to preparecarboxylic acid derivatives including acidanhydrides, ester and amides by reactingacid chlorides with a salt of carboxylic acid,an __________, or an amine respectively.
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


31/44

7. _________ is often used as an analgesic to

relieve minor aches and pains, as anantipyretic to reduce fever and as an anti-inflammatory medication.8. Amide, ester and anhydride are derivatives

of _________.9. _________ have an alkyl (or aromatic) groupattached to a carbonyl function plus alabile(easily displaced) chlorine.10.Acyl chlorides highly reactive entities arehighly susceptible to attack by __________.
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


32/44

REACTANT

CH3COCl + H2O

(CH3CO)2O + CH3CH2OH

CH3COCl + CH3CH2OH

CH3COCl + 2CH3NH2

PRODUCT

CH3COOH + HCl

CH3CONHCH3 + CH3NH3+Cl-

2CH3COOH

CH3COOCH2CH3 + HCl
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


33/44

WIN AND FORTUNE
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


34/44

TYPE OF FORCES
http://video/Aspirin%20Video.flv


35/44

FUNCTIONAL GROUP


36/44

NAME OF ACID


37/44

TYPE OF ACYL CHLORIDE


38/44

SUBSTITUTION


39/44

Acyl Chloride

Introduction

at theOHgroup at

carboxylicacid replacedby the chorine

atom

Physicalproperties

Funtionalgroup

ROCl

IUPACname

Example:EthanoylChloride

Reaction

Water

Alcohol

Primary

amine
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


40/44

Acyl anhydride

Introduction

remove a molecule ofwater between -OH

group at twocarboxylic acid

Physicalproperties

Funtional group

(RO)2O

IUPAC name

replace the word"acid" by

"anhydride".EXAMPLE:ethanoicacid forms ethanoic

anhydride

Reactions

Water

Alcohol

Primary amine
http://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flvhttp://video/Aspirin%20Video.flv


41/44

Answer

Cross

word

Match

them

WIN AND

FORTUNE


42/44

A C Y L A N H E D I R O L H C L Y C A D

S H A S P I R I N F E V E R C I L I N K

A C A R B O X Y L I C A C I D P Y X H R

G H G E R R S A D H G Y C A T L Z Y Y I

P O Q T Y E U F A V Q Y P J O Z X V D V

O C U S F S B J M J P U F H T H G I R B

N O Z E J T U B E C H L O R I N Z D I T

I L F U Z I T R E Q J C K X F D H X D R

F A Z E T H A N O Y L C H L O R I D E O

I T K C K H N Y P A P J E T H A N O S U

C E A C N M O N F D Q P O L A R X K Z B

B U T A N O I C A N H Y D R I D E I I L

A V R U V Z C Y U N J V T E X R I K B E

T D Z S X C A S I R U W Q V S T R I V S

I B V R D E C R N Z S C X O Z E B V B T

O C T E T S I C O O H C L S M I K H K R

N D C O H P D C S M L O V E P O N C O U

E S T E S M S N S E L I H P O E L C U N

D S I A I A C I D G A S E O U S A D I C

G L O B A L W A R M I N G W W S H D A T


43/44

REACTANT PRODUCT

CHCOCl + HO CHCOOH + HCl

(CHCO)O + CHCHOH CHCO(NH)CH +

CHNH+Cl

CHCOCl + CHCHOH 2CHCOOH

CHCOCl+ 2CHNH CHCOOCHCH + HCl


44/44

1.Type of forces ~ Van Der Waals Forces

2.Functional Group ~ Carbonyl

3.Name of Acid ~ Acid Anhydride4.Type of Acyl Chloride ~ Propanoyl Chloride

5.Substitution ~ Nucleophilic Substitution

reaction of acyl chloride and anhydride

Documents