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RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION Digital Transformation in Pharmaceuticals

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Page 1: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

RAPID STRIDES IN GLOBAL HEALTH BY ENABLING

INNOVATION

Digital Transformation inPharmaceuticals

Page 2: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

Business Model

Product

Operations

Research and development

REIMAGINING PHARMA FOR A DIGITAL FUTUREPharmaceutical companies have been focusing on discovering, developing and marketing

medicines but face challenges in managing complex supply chains.

With the advancement in technology , it has become critical for pharmaceutical companies

to focus on competitive pricing structures, product safety and quality / effectiveness of

products. Pharma companies are looking to seize the opportunity to transform their busi-

ness models leveraging emerging technologies such as Robotic Process Automation, Data

Analytics, Internet of Things, along with Hybrid IT ecosystem partnerships

TRADITIONAL FUTURE STATE

• Internally integratedproduct-service mix

• Blockbuster drug model

• White powder drugs

• Generic drugs

• Biotech drugs

• Over the counter

• Assembly line production

• Complex distribution processes

• Trial and error process of drug discovery

• Computer aided drug modelling

• Recycling existing drugs with greater expected health benefits.

• Federated model: Companies typically active in diverse therapeutic areas, equipped to acquire and divest parts of their portfolio.

• Niche specialist: Companies focused on a single therapeutic area or disease.

• Venture variant: Multiple entities collaborating based on sharing of intellectual property/capital growth

• Precision medicine to develop drug variants suitable to diverse patient profiles.

• Lifestyle drugs aimed at improving quality of life

• Smart pills: Ingestible sensors that are swallowed and can record various physiological measures.

• Virtualized Drug Development

• 3D printing enabled drug prototyping

• Pharmacogenomics: Determining the likely response of an individual to therapeutic drugs through genetics

• Rapid reconfiguration of existing manufacturing lines for different products.

• Digital supply chain network operating on dynamic fulfillment models enabled by Demand-driven manufacturing and distribution processes

BUSINESS IMPERATIVES OF INDUSTRY

Inclusion of patient-centric viewpoints and outcomes throughout

the development and commercialization process

Alter the approach to treatment through

therapeutic innovation with technology driven research and discovery

processes

Optimize supply chain with demand-driven manufacturing and

distribution processes

Develop new modes of healthcare delivery by redesigning business

model to ensure alignment of capabilities

with customer needs

Achieve an improved view of the most critical

risks to push accountability for

compliance adherence

Maximize operational

efficiency, quality of production labor and drug manufacturing processes with agile

and flexible technology landscape

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Page 3: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

Hybrid IT as backbone

Key elements of a Hybrid IT infrastructure acting as the building blocks of enabling the implementation of emerging technologies

TECHNOLOGY TRENDS TRANSFORMING THE INDUSTRY

RPA TO REDUCE LEAD TIMES Automate management of packaging tasks like

bottle orientation, capping, labelling and collation systems

Automate ancillary drug manufacturing processes to streamline operational planning, improve cost efficiencies and productivity gainsdevelopment from the outset.

ARTIFICIAL INTELLIGENCE TRANSFORMING CLINICAL TRIAL MANAGEMENT Operationalize data from historical cases,

measure responses to drugs, predict site performances and use predictive criteria for Intelligent trials

Expedite drug discovery process by analyzing huge data sets from sources such as EHRs and clinical trials

3D PRINTING ACCELERATING DRUG DELIVERY3D proto-typing of layer-by-layer fabrication (via computer-aided design models) to formulate drug materials into the desired dosage form

CLOUD COMPUTING FOR IN SILICO DRUG DESIGN Cloud enables collaborated drug development and

clinical research with the application of sophisticated technologies that help companies identify chemical combination of compounds that are better suited for development from the outset

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Page 4: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

SIFY, ENABLINGDIGITAL TRANSFORMATION

SIFY’S CLOUD AND DATA CENTER TRANSFORMATION

SERVICES

SIFY MOVES UPIN GARTNER MAGIC QUADRANT FOR HYBRID CLOUD

Sify has emerged

A CHALLENGER IN PROVIDING MANAGED HYBRID CLOUD HOSTING SERVICESwith unique proposition combining infrastructure, public cloud, connectivity and consistent service delivery.

Figure 1. Magic Quadrant for Managed Hybrid Cloud Hosting, Asia/Pacific

CHALLENGERS

NICHE PLAYERS

BT

NTT CommunicationsFujitsuRackspace

SingtelTelstra

NxtGenOrange Business

Tata Communications

CtrlS

Sify Technologies

IIJ

Source: Gartner (October 2017)COMPLETENESS OF VISION

LEADERS

VISIONARIES

ENABLE SEAMLESS INTEROPERABILITY AND MANAGEMENT OF DATA TO IMPROVE THE SUCCESS RATE OF CLINICAL TRIALS The goal towards developing precision medicine will be achieved by patient data analytics which requires resilient, robust, high-availability infrastructure

INTEGRATE HYBRID IT SYSTEMS ACROSS THE ORGANIZATIONCognitive automation of drug discovery processes shall be powered by AI and RPA, which will require integration of data from multiple sources

SIFY’S TECHNOLOGY INTEGRATION

SERVICES

ACHIEVE PATIENT CONNECT WITH THE USE OF SMARTPHONE APPS, WEARABLES AND OTHER DIGITAL TECHNOLOGIES As the network is uniquely positioned to support the requirements of connectivity, power, scalability, compute, and manageability

ACHIEVE PROCESS EFFICIENCY AND COST-OPTIMIZATION FROM DRUG DISCOVERY TO COMMERCIALIZATION with cloud based erp and distribution management systems. Our capabilities include implementation, migration and application maintenance services for Oracle EBS, SAP S4/HANA, Microsoft Dynamics and Sify's own Forum NXT. Sify’s Application and Platform Services enable setting up the infrastructure and platform environment to meet your business process, employee (self-service, collaboration, productivity, learning) and customer (CRM, security) requirements

REAL TIME MONITORING AND MANAGEMENT Preventive, detective and corrective mechanisms to combat emerging cyber security threats

SIFY’S NETWORK TRANSFORMATION

SOLUTIONS

SIFY’S APPLICATION AND PLATFORM

SERVICES

SIFY’S MANAGED SECURITY SERVICES

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Page 5: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

DIGITAL TRANSFORMATION GOALS

Realign drug development with a patient centric approach

• Create a robust and compliant means of engagement with patients, care givers and other key stakeholders

• Develop an ability to understand and stratify the patient population, including genotype, phenotype, epidemiology, psychology and behaviour

Technology Enablers

Sify Services

Internet Of Things | Cloud | Data Analytics

Sify Services

Therapeutic innovation to transform treatment outcomes

• Streamline drug discoveryprocesses

• Expedite processes across the clinical trial value chain

• Virtual simulation of drug performance

• Rapid prototyping with additive production

Technology EnablersAutomation | Augmented Reality | Cloud | 3D Printing

Sify Services

Manufacturing excellence aided by technological interventions

• Adaptable maintenance processes based on Plant applications data.

• Drive line efficiency with basic yield analytics and contextualization of data

Technology EnablersAnalytics | Automation | Artificial Intelligence

Redesigned Business Model for a sustained and profitable growth

• Improve treatment effectiveness by building partnerships with the healthcare and Lifesciences ecosystem

• Develop new pricing models underpinned by patient information and insights

Technology Enablers

Sify Services

Integrated Platforms| Artificial Intelligence | Data Analytics

Compliance driven business process realignment

Technology Enablers

Sify Services

Integrated Platforms| Artificial Intelligence | Data Analytics

Technology Landscape transformation

• Data Interoperability across platforms

• Modular and agile infrastructure

• On demand scalable IT Landscape

Technology Enablers

Sify Services

Integrated Platforms| Cloud | Modular IT architecture

8 9

• Ensure data privacy, with the move to randomized trials and collecting identifiable data

• Develop intelligent systems to drive automated compliance to applicable regulations like GxP, HIPPA, USFDA regulations etc.

Page 6: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

VPN Services Data Center

Hosting24x7 availability & accessibility to core media platforms

Improved service delivery across omni- channel environment

Managed Services Security Services

Public Cloud Security as

a service

Software Defined DC & Network

IOT integration

Hybrid IT IOT & Managed WiFi Data Center

Transformation Platform &

Application Services Oracle & Microsoft

SIFY’S EVOLUTION AS A DIGITAL TRANSFORMATION PROVIDER

2007

2010

2013

2017

2018

Network & DC Hosting Provider

Managed DC & Network Services Provider

Data Center, Cloud& Network Services Provider

Converged ICT Services Provider (Cloud at the Core)

Application-centric Digital Transformation Partner

Collaboration and integration with partner systems

Product enhancement using analytics

Real-time data through connected devices

Empowering new delivery and payment models through Block Chain technology

Visual assistantsto automate customer service

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Page 7: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

Sify Cloud ServicesIaaS | Private Cloud | Hybrid

Cloud Management

Partner Cloud Services

AWS | Azure | Migration & Management Services lndustry Standard

Applications on Cloud

O365 | SAP on Cloud | Oracle Cloud Service

Sify’s ApplicationServices on Cloud

Forum Next | I-Test

Security Servicesfor Cloud

Unified Collaboration on Cloud

Contact Centre as Service | Video Conferencing as a

Services

Network for CloudSMACnet | Xpress route |

SD Network Services | Digital branches

Cloud BuildPrivate Cloud Build & Managed Services |

Software Defined | Network & Managed Services

Internet of Things

SIFY - CLOUD AT THE CORE

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Page 8: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

Analytics platform with high performance,

massive scale and huge data store capacity for

drug discovery / clinical trials

Externalization to enable collaboration and integration with ecosystem partner systems

Intelligent systems to drive automated

compliance to applicable regulations –

HIPAA, US- FDA regulations etc.

Leverage of new digital platforms for drug

research and development

Zero disruption, high available IT

with agility, flexibility and

hyper-automation

Data protection and long term retention for

records and clinical analytics

BUSINESS DRIVERS FOR ADOPTION OF THE NEW ENTERPRISE DATA CENTER

Service-led view of Data Centre Transformation and Cloud solutionsHybrid IT enabling private cloud for core apps and public cloud for hyper-scale compute and storage resources

Multi-cloud capabilities to leverage right choice of IT across private, public or traditional IT

Public cloud choices across AWS, Microsoft Azure and Sify Enterprise Cloud

Future-ready IT leveraging software-defined network, security, storage, and hyper automation

Application-centric IT architecture for mission critical apps such as SAP, Oracle, Forum NXT, etc.

Backup and DR solution fully complaint to industry regulations with long term protection

Zero-trust security framework across traditional, private, public and enterprise IT

Unified, integrated reporting for predictive analytics, business intelligence and AI

Security blueprinting and compliance on the go for automated audit checks and adherence

Solution Highlights Integrated play across network, Data Center, IT & security

Solution choices across dedicated, public or hybrid models

Aggregation partner across OEM stack, private / public cloud

10 Public and Private Cloud Service providers at 30 + global locations

On-demand provisioning & simplified management – Add on to MPLS network

Premium performance / High resiliency

Traditi

onal

Private

Cloud

EnterpriseCloud

Public

CloudBorderless IT Data Center Connectivity

Unified Reporting | Integrated Security | Standardized GovernanceV

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Software Defined IT | Digital IT Platform

Orchestration | Cloud Federation Collaboration and Mobility

Storage Compute Network SecuritySDS SDN SDSec

Backup/ DR Accelerationsify cloud infinity

CLOUD AND CO-LOCATIONTO ENABLE BORDERLESS IT

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Page 9: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

ScaleWith advent of technologies such as Internet of Things (IoT), cloud and mobility the scale of the network and the end points has grown exponentially

Security Risk of security gaps and absence of uniform security cover across multiple platforms

Agility and SpeedConstant need to support change in the application landscape and ensure continuous service assurance in a global market

ComplexityNon-converged voice and data networks over multiple service providers

Business Drivers for Adoption of Integrated Networking Platform

Service led view of Network transformationService-oriented network architecture to ensure reliable enterprise-grade 24x7 connectivity

Multi-location VPN and Internet services to build a highly reliable WAN setup

Proactive network and security monitoring and management through an integrated network operations center (NOC) & security operations center (SOC)

Global connectivity across cloud nodes for clustered applications, storage replication and disaster recovery services

Deep expertise across cutting edge network and security technologies

SDN(Software defined network) CoE (Center of Excellence) to develop world class SDN centric solutions

Solution Highlights Extensive reach across over 1500+ cities

Global service coverage in over 130+ countries

100G ready DCI and cloud interconnect network in 6 cities

Integrated ITIL based NOC and SOC

Deep skill sets around network and security domain

Cloud enabled services on a consumption model

Internet

MPLS

Sify WAN Transformation

Integrated network and service management delivering high performance

Unified SLA Deliver

transformational WANs to deliver transformational IT projects

Integrated and uniform security management in the enterprise WAN

Operational efficiency

OptimalExpense

management

Integrated and scalable

multi-service network

NETWORK TRANSFORMATION AND CONNECTIVITY Backbone of digital transformation

Enhanced business productivity

Sify’s Network Transformation framework

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Page 10: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

Advanced data breaches using sophisticated techniques

Privacy and data protection

regulations

Increased exposure to hacktivism due to

integration of new technologies

Increasing guidance and frameworks from industry organizations

Business Drivers for securing IT environment

Across Internal and Partner Systems

Service led view of Managed Security ServicesMature threat intelligence and analytics framework with integration of hunting and deception platform

Gartner’s intelligence driven security operations centre

Secure Cloud implementation by building tiered protection layers around data that includes multiple perimeter rings of defense

Secure Connect solution tracks and filters legitimate network connections with customized policies and granular access controls

Secure Data Shield provides bidirectional protection against malicious sources and sophisticated attacks to ensure data integrity and confidentiality

Secure Endpoint Shield stops targeted attacks and advanced persistent threats with intelligent security and layered protection

Sify Assure team delivering audit and compliance around IRDA, IT security guidelines, Best practices benchmarking, ISMS, VAPT, Web App, Mobile App testing Services

Unified dashboard portal based security service delivery

Solution Highlights Comprehensive framework of applicable cyber requirements

Security Transformation capability including Design, Deploy and Managed services

Threat intelligence to reduce risk from unknown vulnerabilities and threats

First provider cyber threat intelligence based security operations

Partnerships with all leading security OEMs and distributor

Automation driven security incident alerting and ticketing

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Seamless Security & Governance Framework

Traditional security boundary The Growing Perimeter Securing with Sify

UNIFIED SECURITY MONITORING AND MANAGEMENTacross Internal and Partner Systems

18 19

Page 11: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

Build a High-QuotientDigital Workforce to Drive Process Efficiencies

Solution Highlights SAP: Application maintenance, implementation services, GST enablement

Oracle: On-Premise and On-Public cloud implementation

Microsoft: Application and platform services on MS Azure, MS Dynamics and MS Office

Fit solution for management of BYOD platform and other mobile engagement solutions

Specialized partners to deliver converged IoT solutions

Scalable solution with rapid addition of WLAN nodes

IoT Enabling Dynamic Real Time Access to New Information

Complete visibility

Integrated ICT

offering

Sify Infra-

structure

Partner platform

Sify Domain

Expertise IoT integration

Managed service

OUTCOME BASED MODEL

ANALYTICS

Service led view of turnkey IoT solutions

Business drivers for creating a connected ecosystem

Creation of an agile, responsive,

automated and business-aligned

IT environment

Accelerate product development to stay current and

relevant

Turn real-time data into insight, action and new business models through ubiquitous connectivity

Build a more efficient workforce and transform underlying process by connecting people with data

Achieve faster time-to-market

products within a complex multi-vendor

environment

Cost-optimization through reduction in

hardware and resource costs for

system management

Cloud-based solutions with scalable and elastic capabilities

Improved transparency and visibility within the organization through resilient platforms

IoT in Pharma Real-time dynamic scheduling of

shop-floor activities.

Predictive maintenance of machines and equipment

Real-time logistics visibility using RFID and sensors

Collect metadata for analysis to identify and reduce causes of process variability

Track storage conditions of sensitive drugs.

Business Drivers for securing IT environment

Employee Productivity

Digital Security

Customer Engagement

PLATFORM HYBRID IT - As a Service

Enabling Management

Service led view of application and platform services

HR and Benefits Customer Lifecycle management

Digital Certificates and PKI

Risk Management

BI/ Analytics

Software Platform Data BaseInfrastructure

CRM demand

INTERGRATION

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Page 12: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

Engagement model – Less hardware, Less people and Less license

ENGAGEMENT MODELS

Outcome based Client engagement is based on defined business outcome generated by IT solutions and services

PLATFORM

Assets + Services Systems are owned by the client and annuity

based payout for services

Usage-based No upfront investment by client and payout is based on consumption

Component-based Reduced upfront investment as client

subscribes to infrastructure owned by Sify as a part of their overall infrastructure

requirement

+ +

Service payout

From traditional Tools

Process approach

Service Catalogue ApproachPeople

Determine Performance

Score

Define KPI

Define SLA

Service will be

Defined

Elements of Service Catalogue – Illustrative

Elements of Service Catalogue – Illustrative

TotalService Charges

Perfor-mance Score

Payout Eligible

Service Catalogue Based Payout

Asset Management related service

Email and Directory related servicesEnd User System related services

Service Desk related services

Total Payout

Vendor Management related servicesWebsite management related services

Service Delivery Management (ven-dor's tool cost will be included here as tools enable the service delivery and management.)

IT Operations

Backup, Restore and Archival related services

Critical SLA Metrics

Operational Metrics

SLA Reporting

Service Catalogue

Service catalogue based managed services frameworkENGAGEMENT APPROACH

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Page 13: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

AIROLI MUMBAI10 MW

VASHI MUMBAI III1.6 MW

RABALE MUMBAI III20-40 MW

RABALE MUMBAI II10-12 MW

RABALE MUMBAI20 MW

Mumbai

Airoli

Cloud ready

Cloud ready

Chennai III30-40 MW

Chennai II20-30 MW

Chennai1.6 MW

Bangalore II10-20 MW

Bangalore3.2 MW

Hyderabad Upto10 MW

Noida, Delhi10 MW

OUR MAJOR DATA CENTERS AND CLOUD CENTERS FOOTPRINT

OUR NETWORK FOOTPRINT

Total capacity of 455,000 sq. ft. of server farm

Location

Mumbai 120,000 250,000 June 18

June 19

Dec 18

Available

Available

70,000

30,000

55,000

50,00016,000

55,000

12,000Chennai

Hyderabad

Delhi

Bangalore

Existing in sq ft Future in sq ft Readiness

Existing Upcoming cloud ready

Network nodes across India2200+Access metro

rings in 10 cities

Concurrently-MaintainableHierarchical topology for better scalability

90000+Enterprise Circuits

Cities Coverage1550

International PoPs

10G

Cable Routes

3000+Cities

130+Countries

APCN2+RNAL

APOLLO

TGN-A

TGN-A

GULF BRIDGE International

Europe – India Gateway

SEAMEWE

I2I+TICSMW4

LACSAPCN2

EAC APCN2+RNAL

India

Singapore

Chennai

Mumbai Hong Kong

Dubai

Marseille

London

New York 60 Hudson

Los Angeles

24 25

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OUR CLIENTS OUR PARTNERS

Security

Application

Cloud & Acceleration

Technology Partners

AWARDS & ACCOLADES

National Award for Best Technology for Social

Case for Department of post by Cyber Media

Sify is a Business

Superb brand

CIO Review recog-nized Sify in the cloud managed service vertical

Most Promising Brand by WORC

Integrated Data Centre

Solutions

Managed Network Solutions

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Page 15: RAPID STRIDES IN GLOBAL HEALTH BY ENABLING INNOVATION · • 3D printing enabled drug prototyping • Pharmacogenomics: Determining the likely response of an individual to therapeutic

India - HeadquartersSify Technologies Limited II Floor, TIDEL Park, No.4, Rajiv Gandhi Salai,Taramani, Chennai - 600 113, India.

SingaporeSify Technologies (Singapore) PTE Limited 30 Cecil Street, #19-08 Prudential TowerSingapore 049712

United KingdomSify Technologies Limited 63 St Mary AxeEC3A 8AA, London, United Kingdom

United States of AmericaSify Technologies North America Corp.5201 Great America Parkway, Suite 132Santa Clara, California 95054, USA

DubaiSify Technologies LimitedP. O. Box 500522,Office no. 1717, Shatha Towers,Dubai media city DubaiThe United Arab Emirates.

Our end-to-end ICT solution to

• Data Centre Transformation (Cloud) and Infrastructure services

• Network Transformation and Connectivity services• Technology Integration services

• Application and Platform services• Managed Security services• Internet of Things

[email protected]

+91 8750442233