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Page 1: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Radiology - introduction

Page 2: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Purpose of training

Provision of clinically

relevant basic knowledge:

– indications,

– diagnostic algorithm

– accuracy of diagnostic

imaging and interventional

radiology.

Prof. András Palkó MD, PhD, chairman

Assoc. Prof. Endre Nagy MD, PhD, educational advisor

Page 3: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Sources of information

Textbook Gunderman RB: Essential Radiology 2nd ed., Thieme, New York, 2006

Lectures Clinically oriented, slides available at

http://www.szote.u-szeged.hu/medcentrum/radiology/

Seminars Clinically oriented, case-based

Teaching files Appr. 800 images with comments on

http://www.szote.u-szeged.hu/medcentrum/radiology/

Page 4: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Exam

Core knowlegde: textbook + lecture + seminar

1st semester: MCQ test

2nd semester: oral – questions & images available on the website

Page 5: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Curriculum

Page 6: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 7: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Radiology =

diagnostic imaging +

therapeutic intervention guided by imaging procedures

OR

the art of interpreting visual information by the use of very complex equipment creating very complex

images

Page 8: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

• Roentgen: x-ray 1895

• Cannon: contrast material (bismuth) 1896

• Krause: “ (barium) 1904

• Graham: brachial arteriography 1923

• “ : cholecystography 1923

• Swick: i.v. pyelography 1928

• Donald: ultrasound (sonar) 1950

• Seldinger: catheter-technique 1953

• Hounsfield: CT 1967

• Lauterbur: MR 1973

DIAGNOSTIC IMAGING

Page 9: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

1895

Page 10: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

1900 1925 1950 1975 2000

X-ray radiogr. tomography PP, DDR

fluorosc. image intensifier DSA DF

intervention CT MDS-CT

US MR fMR

Ba iodine non-ionic Gd US

double contrast

The avalanche PACS, RIS

teleradiology

The Magic Mountain

Page 11: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

DIAGNOSTIC IMAGING

Purpose: create visible image of morphology and function of the human body

Image: visual information (visualization in 2 or 3 D, vector, curve, spectrum, etc.)

To bring about an image:

– Energy has to be conducted to the body

– Interaction of the energy and the components of the body

– Detection of the modified energy

– Visualization of the detected pattern

Page 12: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Types of imaging:

• absorption (X-ray, CT) • reflection (ultrasound) • induction (MRI) • emission (NM)

DIAGNOSTIC IMAGING

Page 13: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Types of imaging:

• absorption (X-ray, CT) • reflection (ultrasound) • induction (MRI) • emission (NM)

DIAGNOSTIC IMAGING

Page 14: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Types of imaging:

• absorption (X-ray, CT) • reflection (ultrasound) • induction (MRI) • emission (NM)

DIAGNOSTIC IMAGING

Page 15: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Types of imaging:

• absorption (X-ray, CT) • reflection (ultrasound) • induction (MRI) • emission (NM)

DIAGNOSTIC IMAGING

Page 16: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

• image generation

• image reading

• image interpretation (report)

• data processing and archiving

DIAGNOSTIC IMAGING

Page 17: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

indication

examination

clinical problem

therapy

consultation

consultation

DIAGNOSTIC IMAGING

Page 18: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Methods:

• x-ray

• ultrasound

• computed tomography

• magnetic resonance imaging

• (PET-CT)

• (optical imaging)

• (thermography)

DIAGNOSTIC IMAGING

Page 19: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

– full digital imaging

– „intelligent” equipments

– 3D, virtual reality, functional imaging

– genetically modified, molecular markers

– biologically specific contrast materials

– PACS, neural network, automatic image reading and interpretation

Trends of development:

- faster, easily generated, more relevant information - shorter way to diagnosis

Page 20: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Stagnation or progress?

Thomas W. Lawson, 1902

Page 21: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Thomas W. Lawson, 1902 Clermont, 1807

Stagnation or progress?

Page 22: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Where are we today?

Page 23: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Cardio-CT

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Department of Radiology, University Medical School, Szeged

Cardio-MR

Page 25: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Cardio-MR

Page 26: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

MR-phlebography

Page 27: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

CT-arteriography

Page 28: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

CT-arteriography

Page 29: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

CT-arteriography

Page 30: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

DSA

Page 31: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

CT-arteriography

Page 32: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

MR-tractography

Page 33: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Functional MRI

Page 34: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

MR-spectroscopy

Page 35: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

CT-endoscopy

Page 36: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Computer-assisted detection

Page 37: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Automatic segmentation

Page 38: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Hybrid imaging (UH - CT/MR)

Page 39: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Hybrid imaging (PET/SPECT – CT/MR)

Page 40: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Dilemmas of development:

lower back pain – MRI vs. acute abdomen – CT

Page 41: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

The future

Integrated diagnostics

Mass computing

Page 42: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

X-ray imaging

Page 43: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 44: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 45: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 46: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Absorption of x-ray is influenced by:

• wave-length of radiation3

• atomic number4 • density • thickness

Page 47: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 48: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

X-ray tube

patient

detector

(film, dd)

Radiography

Page 49: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Radiography

Page 50: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

image intensifier

TV monitor

detector

(fluoro screen)

Fluoroscopy

Page 51: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Fluoroscopy

Page 52: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

negative image

positive image

Page 53: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Analog x-ray imaging

Detector

– Film (emulsion suffering photochemical reaction if exposed to x-ray and light; image visible after development)

– Fluoroscopic screen (scintillates if exposed to x-rays; image visible directly or by an image intensifier – TV set)

Page 54: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

+ =

Page 55: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 56: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 57: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Digital x-ray imaging

Detector: – storage phosphor plate (radiogram, digital

read-out by laser-light) = computed radiography, CR

– Direct digital detector (radiogram and fluoroscopy)

– Both visible on computer monitor

Page 58: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

mirror

photo-electro-multiplyer

electric

signal

digital information image plate

optic fiber

Page 59: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 60: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 61: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Digital imaging

Today:

– Digital archive and communication (picture archive and communication system, PACS)

– Computer assisted detection (CAD)

– Image optimization

– Teleradiology

– Electronic patient record

In the future (Web 2, cloud computing)

– Data mining, decision support

Page 62: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 63: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

X-ray tube

X-ray

body detector

lesion

shadow

collimation

Page 64: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

X-ray tube X-ray object

shadow

Page 65: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

X-ray tube X-ray object

shadow

Page 66: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

X-ray tube X-ray object II.

shadow

object I.

Page 67: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 68: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

X-ray tube X-ray

object

focus

(shadow)

Page 69: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

X-ray tube X-ray

object

focus

(shadow)

Page 70: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

X-ray imaging:

• magnification

• distortion

• summation

• loss of data

Page 71: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 72: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 73: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

X-ray imaging:

• magnifies • distorts • summarizes • forgets

The solution:

• more than one direction • tomography

Page 74: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 75: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 76: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Poor contrast resolution

Page 77: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Solution:

low voltage

contrast material

other modalities

Poor contrast resolution

Page 78: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 79: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

Page 80: Radiology - introduction · Department of Radiology, University Medical School, ... MCQ test 2nd semester: oral ... –Data mining, decision support

Department of Radiology, University Medical School, Szeged

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Department of Radiology, University Medical School, Szeged