raat - brisbane diamantina health partners · 2014. 6. 19. · raat was conceived as a component of...
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RAAT Rapid Access Model of Care in HCV
Marrianne Black CN Cheryl Sendall CNC
Dr Caroline Tallis/Dr Rebecca Ryan Elizabeth Peat/Courtney Balk/Mirjana Palezevic AO
Special thanks for the support and input of
Professor Gerald Holtmann and Dr Katherine Stuart.
What is RAAT?
Not this:
It is:
Rapid Access to Assessment and Treatment.
An Innovative Model of Care.
Epidemiology in Queensland
Second highest number of patients with HCV to NSW .
2696 new cases reported per year. Approximately 45,000 HCV infected
patients in Queensland. PAH has highest incidence of newly
reported cases in the state.
Background The burden of HCV related complications will
continue to rise over the next 3 decades. There will be a significant percentage of HCV related
cirrhosis, many with decompensated liver disease and HCC.
The current level of burden in Australia of untreated HCV in Australia is estimated at: 9474 estimated cases of cirrhosis. 4829 cases of liver failure. 2438 cases of hepatocellular carcinoma 873 liver transplants. (www.hepatitisaustralia.com)
Burden Projected Prevalence of Chronic HCV,
Cirrhosis, and Complications
Davis GL, et al. Gastroenterology. 2010;138(2):513-521 e516.
Projected Number of Patients With Decompensated Cirrhosis and Hepatocellular Carcinoma
Num
ber o
f Cas
es
160,000
140,000
120,000
100,000
80,000
60,000
40,000
20,000
0
Year1950 1960 1970 1980 1990 2000 2010 2020 2030
Hepatocellular Carcinoma (HCC)Decompensated Cirrhosis
Why did we consider this new model of care? KEY POINT Demand for liver outpatient services far exceeded capacity ISSUES At the time the number of patients on the waiting list = 1309 Waiting times far exceeded the recommended and acceptable
timeframes. Local population – much undiagnosed chronic liver disease
Immigrant population Also a Primary health care issue
Future demand will only increase further with current calculations
Growth of cases of chronic liver disease Increased growth of hepatocellular carcinoma cases
Early and late stage presentation
Waiting times as at January 2012. Cat 1 –
Number 44 Waiting time 11 weeks
Cat 2 – Number 481 Waiting time 26 months
Cat 3 – Number 722 (most of which are referred with
HCV) Waiting time 6 years, 5 months
Potential Risks Adverse Events:
progression disease on waiting list “Image” of our waiting list:
nationally and internationally Potential cost saving longer term Impact on Hospital stays:
CLD management, HCC management longer term
Let alone impact on QALY for the patient.
Why did we establish this new model of care?
RAAT was conceived as a component of the FibroScan project.
Following consideration of all the factors already outlined and the potential adverse effects to our patients, this innovative model of care was established.
In the beginning:
The initial plan: To review and rationalise the Long Wait
Category 3 Hepatology Outpatient List. To review those patients with viral hepatitis
who would be suitable for treatment/trials. To screen Category 3 patients for CLD
(chronic liver disease).
In the Beginning:
Clinical Audit: 890 charts reviewed. Referrals placed on waiting list from
10/8/2005 to 30/6/2013.
Clinical Audit
Assessment of referrals: Suitable for treatment -> RAAT clinic Suitable for trials -> RAAT clinic -> refer to
trials. Stay on waiting list for now – (non- viral,
or not suitable for RAAT)
Findings from clinical audit
50 Patients with Hepatitis B. These patients were deemed a priority for RAAT assessment.
523 Patients with Hepatitis C 301 Patients to remain on waiting list as
not suitable for RAAT clinic. 2 patient deaths whilst waiting were
identified.
What we needed
Increase Staffing – all levels Administrative Nursing, include specialist nursing Medical
Infra - structure – Consulting rooms already available Laboratory resources available Radiology resources available
Proposed Structure
6 new cases per clinic session– initially HBV and HCV. This was quickly increased to 10 new cases per clinic.
Friday PM – Gastroenterology OPD, Level 4: 1230-1530. This clinic will also have access to the FibroScan
Patients with Hepatitis B
Assessment in RAAT clinic. FibroScan undertaken, Ultrasound and
Blood tests ordered. Follow up at Burke St and management
plan implemented. Details also provided to Trials co-
ordinators.
HCV patients seen in Friday PM RAAT clinic 209 patients (to 4/4/2014). 132 males FibroScan results: 18 patients with LSM >12kPa 57 patients with LSM >7kPa and <12kPa.
Not all patients were treated due to either
Being too sick to commence treatment. Significant co-morbidities. Personal preference to delay or not undergo treatment (Warehouse)
3 patients have been identified with HCC. 5 patients have been identified with de-compensated liver disease
Total number of patients seen in Friday PM RAAT clinic 29/6/2012 to 4/4/2014.
0
100200
300400
500600
700800
900
# booked #DNA # Seen #Resched
# Cx Prev DNA SecondDNA
Patie
nts
Patients with HCV treated:
62 patients commenced treatment
8 patients accessed clinical trials 54 RAAT HCV treatment
8 cirrhosis
Results Thus Far
~ 90% RVR SVR 10 TPV – 12 BOC – 5
Previous Culture regarding HCV treatment.
Warehouse. Trials Treatment.
There is a shift away from warehousing
patients.
Authors: Jennifer A Whitty, Caroline Tallis, Kim-Huong Nguyen, Paul A. Scuffham, Paul Crosland, Kaye Hewson, Rehka Pai Mangalore, Marrianne Black, Gerald Holtmann
Cost-effectiveness of RAAT.
Waiting times Where we started Cat 1
Number 44 Waiting time 11 weeks
Cat 2 Number 481 Waiting time 26 months
Cat 3 Number 722 Waiting time 6 years, 5
months
AS AT 4/4/2014
Cat:1 Number 0 Waiting time 0 weeks
Cat: 2 Number 233 Waiting time 7 months
Cat:3 Number 257 Waiting time 2 years 3
months
Disclaimer
To ensure equity all patients to 1/1/2012 have been seen in the RAAT clinic.
All Category 3 patients with HCV deemed suitable for RAAT clinic have been seen from the waiting list with referrals received prior to June 2013.
Thank-you Special thanks to Cheryl Sendall for establishing the Treatment clinic. Elizabeth Peat, Courtney Balk and Mirjana Palezevic
AO for the booking of the appointments. The Gastro OPD admin staff for their help with
checking in these patients. And special mention to the team at Burke Street for
their work in commencing some of the patients in this co-hort.
The next phase To date greater than 2100 patients have
undergone a FibroScan procedure since the introduction of this new technology to our department.
ARFI (acoustic radiation force impulse) has been trialled in the assessment of liver fibrosis in patients with liver disease.
The Future: Supersonic Aixplorer is now undergoing trials
within this department in the assessment of fibrosis for our patients.
And then.
Perhaps we can stop the RAAT clinic and go to the CAT clinic.
Completed Anti-viral Therapy.
Thank you.