quick end points in zebrafish drug discovery
TRANSCRIPT
PENTAGRIT RESEARCH Quick End Points in Zebrafish Drug Discovery
Model: Developmental
ToxicityInduction: ChemicalEnd Point: HT Motor
Scan
Model: Brain TumorInduction: Surgery
End Point: Fluorescent Viability
Model: Muscular Dystrophy
Induction: Chemical End Point: Muscle
Pathology
Model: HepatocarcinomaInduction: SurgeryEnd Point: Tumor
Development
Model: HepatocarcinomaInduction: Surgery
End Point: Liver Pathology
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Model: Hepatomegaly with Liver Cirrhosis
Induction: Chemical + Elicitors
End Point: Liver Pathology
Model: Cardiovascular Hypertrophy
Induction: Chemical + Elicitors
End Point: Cardiovascular Pathology
Model: Dementia with Plaques
Induction: Surgery End Point: Brain Pathology
Model: Regeneration Model
Induction: Surgery End Point: Blastema cell
differentiation
Model: Parkinson’sInduction: Surgery
End Point: Altered Motor and Cognition
Model: Alzheimer’sInduction: Surgery +
ChemicalEnd Point: Anxiety &
Dementia
Normal Model Normal Model