quality control of baby care products by ashwini

G.ASHWINI

M.PHARMACY 1/1

ROLL NO 100809885003

OUCT

QUALITY CONTROL OF

BABY POWDERS AND

SHAMPOOS

G.ASHWINI

M.PHARMACY 1/1

ROLL NO : 100809885003

OUCT

www.pharmacygraduates.org

CONTENTS

INTRODUCTION

ANATOMICAL DIFFERENCE BETWEEN

BABY AND ADULT SKIN

PHYSIOLOGICAL DIFFERENCE BETWEEN

BABY AND ADULT SKIN

BABY POWDERS

FORMULATION

EVALUATION

BABY SHAMPOOS

FORMULATION

EVALUATION


Need different skin and hair care

Their exist anatomical and physiological differences

The skin of the newborn is “unripe”.


EPIDERMIS:

Only in prematures

The stratum corneum is lacking, a significant barrier function , photoprotection, immunological barrier, and receptor function, respectively—still has to develop progressively.

The stratum germinativum , melanocytes are less pigmented, which explains the pale color of the newborn’s skin.


In the dermis, numerous fibroblasts produce elastic and collagen fibers but fewer in

number than in adult life.

It is known that the dermal matrix differs in

composition depending on age. Indeed, during

development, the water, glycogen, and hyaluronic acid contents of the matrix

decrease, but its dermatan sulfate content increases


Dermal absorption in newborn skin is similar to that observed in adult skin. For babies, however, a number of typical risk factors exist.

The surface area/body weight ratio is 2.3-fold higher in newborns than in adults .

Pharmacokinetic parameters differ widely between babies and adults .


BABY CARE PRODUCTS:

Baby care products are defined as the paediatric cosmetics which usually contain harmless ingredients that make no or therapeutic value and is used more or less to prevent rather than cure undesirable skin problems.

Different kinds of baby care products are baby creams, baby lotions, baby oils, baby powders, baby shampoos, etc..,.


BABY

POWDERS

BABY POWDERS


Formulation:

Talc : 70% Magnesium stearate : 6.0%

light calcium : 24.0%

carbonate

Perfume : q.s

Baby powders are used for

the maintenance of

Epidermal physiology and the

skin care in the new borns.


Shade control and lighting: Pressure testing: Flow property Particle size determination


Abrasiveness

Breakage test

Stability

Sterlity test


BABY SHAMPOOS


FORMULATION: Surfactants 15-30%

Foam Stabilizers 1-4 %

Thickener 0-5%

Deionized Water Q.S

Baby shampoos are

used to clean the scalp

and the hair of the

babies


Preservatives 0,1-1 %

Humectants 1-5 %

PH Buffers Q.S. neutral pH

Chelating Agents 0-0,02 %

Pearlescing/ opacifying agents 0,2-2%

Perfume 0,5-1 %

Colouring agents Q.S.

Conditioning agents Q.S. desired effect


Evaluation of Safety Skin toxicity test.

Eye toxicity test.

Evaluation of antimicrobial activity


six rabbilts are selected

On skin of each rabbit round patch is made by removing hair

Dilute preparations of 8-10% are applied on to patches of all

rabbits

Shampoo is allowed to for aperiod of 3-4 hrs and wash it

completely

After effieicent washing skin is observed for any adverse

reactions


Six rabbits are selected

Test eye control eye

Apply product

Wash it after 20 sec,

5min and 24 hrs

Observe at 1hr,24hrs,48hrs,

7th day and 14th day

Washed on first day and after 24

hrs


Since shampoos are liquid or viscous preparations, they are liable to microbial growth. Hence the preservative is added to prevent the microbial growth. This test is usually done by a method called as “Challenge study”.

According to this study, the product is said to be preserved when it does not support microbial growth even after repeated attacks of various micro-organisms.


Intially app. Starin of micro organism is selceted and is considered

as test organism

Culture of test organism is prepared

The product is inoculted repeated in culture media and studies are

Carried out for 10- 12 weeks

Along with test ,control samples are prepared and reserved for reference

Usaually two types of control samples are prepared i.e., one sample

long with preservative and with out preservative

The test comes to conclusion only when it has been proven that has not

supportedMicrobial growth www.pharmacygraduates.org

Baby skin is very sensitive than adult, so we should take a lot of care

What ever we are applying should be

Non toxic

Non irritant

Free from microbial contamination

Totally it must be mild and Safer to use.


Sharma PP. Cosmetics-formulation, manufacturing

and quality control. 3rd ed., Vandana Publications

Pvt. Ltd., Delhi, 2005.

Nanda S, Nanda A, Khar RK. Cosmetic technology.

Brila Publications Pvt. Ltd., Delhi, 2007.

Amparo Salvador, Alberto Chisvert. Analysis of

Cosmetics products. 1st ed., Elsevier Publications

Pvt. Ltd., U.K, 2007.

Andre O. Barel, Marc Paye, Howard I. Maibach.

Hand book of Cosmetic Science and Technology.

3rd ed., Informa Healthcare USA, 2009.


quality control of baby care products by ashwini

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