qnl 19 february 2020 v3 mac.docx...the elixir director niklas blomberg informed on the elixir...

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Page 1 Issue 1/20 www.denbi.de This de.NBI Quarterly Newsletter in February 2020 informs about recent developments and current events in the project German Network for Bioinformatics Infrastructure – de.NBI. Further information at: https://www.denbi.de/ SYMPOSIUM CELEBRATING THE 5 TH ANNIVERSARY OF THE de.NBI In March 2015, the German Ministry of Education and Research (BMBF) launched the de.NBI project with the aim of establishing a Germany-wide bioinformatics infrastructure offering bioinformatics service, training and international cooperation. Now, five years later, the network is operating very successfully and celebrated its 5th anniversary with a symposium on 13 February 2020 at the Seminars CampusHotel in Berlin. More than 150 scientists took part in the symposium, most of them members of the network, but also the Scientific Advi- sory Board, members of the reviewer team, members of the de.NBI Industrial Forum, and representatives of the Ministry and project management. The symposium was opened by the BMBF representative Matthias Kölbel who focused on the successful establishment of the bioinformatics infrastructure which now needs a sustainable continuation. In the first session, the de.NBI coordinator Alf Pühler started with an overview on the de.NBI highlights, followed by three de.NBI presentations focusing on bioin- formatics for humans, plants and microbes. In the second session external experts presented their views on specific as- pects of the de.NBI network. The ELIXIR director Niklas Blomberg informed on the ELIXIR organization and its coopera- tion with de.NBI. Rolf Apweiler, director of EMBL-EBI, used his talk to report on digital medicine in Germany and Europe. Finally, Dietrich Rebholz-Schuhmann, director of ZB MED Information Center for Life Sciences, presented his institute engaged in handling of research data in the life science. Find more information at: https://www.denbi.de/events/661-sab-meeting-2020 Further reading on the web pages of PtJ and BMBF: 1) https://www.ptj.de/ueber-uns/aktuelles?backRef=83&news=Fuenf_Jahre_Deutsches_Netzwerk_fuer_Bioinformatik_In- frastruktur_deNBI 2) https://www.bmbf.de/de/bioinformatik-detektivarbeit-im-erbgut-10896.html THE 4 TH SAB MEETING OF THE de.NBI In the frame of the 5 th anniversary meeting of the de.NBI network, the de.NBI Scientific Advisory Board (SAB) assembled for its annual meeting on 13-14 February 2020 at the Seminaris CampusHotel in Berlin. The current SAB consists of 8 internationally renowned bioinformaticians from Austria, France, Germany, Luxembourg, Spain, Sweden and the Netherlands and is chaired by Reinhard Schneider from Luxembourg. The task of the SAB is to collect information on the de.NBI development and to advise the de.NBI network on its future development. For this meeting the de.NBI Status Report was presented which contains the reports of the coordinators of the service centers and CONTENT: 1) Symposium celebrating the 5 th anniversary of the de.NBI 1 2) The 4 th SAB meeting of the de.NBI 2 3) 6 th de.NBI plenary meeting 2 4) de.NBI highlights brochure 2 5) ELIXIR Germany Collaboration Agreement signed 3 6) Björn Grüning (RBC) appointed as lead of the ELIXIR tools platform 3 7) Stephan Fuchs (RKI) affiliated as associated de.NBI partner 3 8) Johannes Werner (IOW) associated as de.NBI training partner 4 9) The de.NBI in the context of artificial intelligence 4 10) Guidelines for de.NBI services adopted 5 11) New record: 1586 training course participants in 2019 5 12) UseGalaxy.eu provides human multi-omics data from PGP-UK 5 13) Initial analysis of Wuhan Pneumonia Virus (COVID-2019) using galaxy, bioconda and public research infrastructure … 6 14) News from the de.NBI office 6 15) Recent Updates of de.NBI Services 6 16) de.NBI @ conferences 7 17) Upcoming events 7 18) Impressum 8

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Thisde.NBIQuarterlyNewsletterinFebruary2020informsaboutrecentdevelopmentsandcurrenteventsintheprojectGermanNetworkforBioinformaticsInfrastructure–de.NBI.

Furtherinformationat:https://www.denbi.de/

SYMPOSIUMCELEBRATINGTHE5THANNIVERSARYOFTHEde.NBI

In March 2015, the GermanMinistryofEducationandResearch(BMBF) launchedthede.NBIprojectwiththeaimof establishingaGermany-widebioinformatics infrastructureofferingbioinformaticsservice, training and international cooperation.Now, five years later, the network isoperatingverysuccessfullyandcelebratedits5thanniversarywithasymposiumon13

February2020attheSeminarsCampusHotelinBerlin.

Morethan150scientiststookpartinthesymposium,mostofthemmembersofthenetwork,butalsotheScientificAdvi-soryBoard,membersofthereviewerteam,membersofthede.NBIIndustrialForum,andrepresentativesoftheMinistryandprojectmanagement.

ThesymposiumwasopenedbytheBMBFrepresentativeMatthiasKölbelwhofocusedonthesuccessfulestablishmentofthebioinformaticsinfrastructurewhichnowneedsasustainablecontinuation.Inthefirstsession,thede.NBIcoordinatorAlfPühlerstartedwithanoverviewonthede.NBIhighlights,followedbythreede.NBIpresentationsfocusingonbioin-formaticsforhumans,plantsandmicrobes.Inthesecondsessionexternalexpertspresentedtheirviewsonspecificas-pectsofthede.NBInetwork.TheELIXIRdirectorNiklasBlomberginformedontheELIXIRorganizationanditscoopera-tionwithde.NBI.RolfApweiler,directorofEMBL-EBI,usedhistalktoreportondigitalmedicineinGermanyandEurope.Finally,DietrichRebholz-Schuhmann,directorofZBMED InformationCenter forLife Sciences,presentedhis instituteengagedinhandlingofresearchdatainthelifescience.

Findmoreinformationat:https://www.denbi.de/events/661-sab-meeting-2020

FurtherreadingonthewebpagesofPtJandBMBF:1) https://www.ptj.de/ueber-uns/aktuelles?backRef=83&news=Fuenf_Jahre_Deutsches_Netzwerk_fuer_Bioinformatik_In-

frastruktur_deNBI2) https://www.bmbf.de/de/bioinformatik-detektivarbeit-im-erbgut-10896.html

THE4THSABMEETINGOFTHEde.NBIIntheframeofthe5thanniversarymeetingofthede.NBInetwork,thede.NBIScientificAdvisoryBoard(SAB)assembledforitsannualmeetingon13-14February2020attheSeminarisCampusHotelinBerlin.

ThecurrentSABconsistsof8internationallyrenownedbioinformaticiansfromAustria,France,Germany,Luxembourg,Spain, Swedenand theNetherlandsandis chairedbyReinhardSchneiderfromLuxembourg.The taskof theSABis tocollect informationon the de.NBI development and to advise the de.NBI networkon its future development. For thismeetingthede.NBIStatusReportwaspresentedwhichcontainsthereportsofthecoordinatorsoftheservicecentersand

CONTENT:1)Symposiumcelebratingthe5thanniversaryofthede.NBI 12)The4thSABmeetingofthede.NBI 23)6thde.NBIplenarymeeting 24)de.NBIhighlightsbrochure 25)ELIXIRGermanyCollaborationAgreementsigned 36)BjörnGrüning(RBC)appointedasleadoftheELIXIRtoolsplatform 37)StephanFuchs(RKI)affiliatedasassociatedde.NBIpartner 38)JohannesWerner(IOW)associatedasde.NBItrainingpartner 49)Thede.NBIinthecontextofartificialintelligence 410)Guidelinesforde.NBIservicesadopted 511)Newrecord:1586trainingcourseparticipantsin2019 512)UseGalaxy.euprovideshumanmulti-omicsdatafromPGP-UK 513)InitialanalysisofWuhanPneumoniaVirus(COVID-2019)usinggalaxy,biocondaandpublicresearchinfrastructure… 614)Newsfromthede.NBIoffice 615)RecentUpdatesofde.NBIServices 616)de.NBI@conferences 717)Upcomingevents 718)Impressum 8

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thechairpersonsoftheSpecial Interestgroups.Thede.NBIcoordinatorandtheHeadoftheadministrationofficecon-tributedachapteronstructure,organizationandtasksofthenetwork.

ThecollaborationwithELIXIRwaselaboratedintheELIXIR-DEre-portasaseparatedocument.Apostersessionwasheldintheeven-ingofthefirstdaytoinformaboutthedevelopmentsandachieve-mentsintheindividualde.NBIprojects.TheseconddayoftheSABmeetingwasthenusedbytheboardtodevelop a recommendation document. In a feedback session themainstatementsofthisdocumentwerepresentedtothede.NBIau-dience.Insummary,theoveralldevelopmentofthede.NBInetworkwashighlyappreciated,butitwasclearlystatedthatthesustainablecontinuationof thenetworkas awhole shouldbe thegoal forthefuture.

FindmoreinformationontheSABat:https://www.denbi.de/organisation/scientific-advisory-board-sab

6THde.NBIPLENARYMEETINGThede.NBIandELIXIR-DEplenarymeetingtookplaceon14February2020.125de.NBImembersparticipatedinthetwosessionsfocusingonthereportofthede.NBIcoordinatorandtheplansoftheServiceCentersandSIGSforthenextprojectphase(bridgephase)thatstartsinMarch2020.InthesecondsessionA.TauchsummarizedthedevelopmentofELIXIRGermanywithfocusonthenowcompletedlegalframeworkconsistingofthecollaborationagreementandtheGermanconsortiumtreaty.B.GrüningandA.GoesmanngaveinsightsintothetasksofthetechnicalcoordinatorandtheELIXIRboard,respectively.Thenewgroupphotoofthede.NBIconsortiumshowsastillgrowingcommunity.

de.NBIHIGHLIGHTSBROCHURETomark the occasionof the 5th anniversary of the de.NBInetwork in 2020, thede.NBI Administration Office presented the brochure entitled “Von der Date-nanalysezumVerstehenkomplexerbiologischerSysteme”whichfeaturescon-tributionsfromde.NBIServiceCentersandprojectspartnersandprovidesinfor-mationon thediverseactivitiesof thede.NBInetwork.Thebrochure showcasesthecontributionofde.NBIasanationalbioinformaticsinfrastructureinthefieldoflife sciences and provides solid information about the advancement of researchconducted in the field of big data on a national level. In order to target a largeamountofreaders,thebrochureispresentedintheGermanlanguage.Thedocu-mentisdividedintofourchapters,namelytheplant,microbialandmedicalbioin-formaticsfollowedbythedescriptionofthede.NBInetworkanditsactivitiesinthefieldsservice,training,cloudcomputing,andindustrialpartnership.Theinterplayofresearchactivitiesbetweenbiotechnology,molecularbiology,genomeresearch,systemsbiology,medicineandbioinformaticsispresentedfromdifferentperspec-tives.Thebrochurealsoincludesaninterviewwiththede.NBIcoordinatorandtheheadoftheadministrationofficeanddiscussesthestructureandorganizationofthenetworkaswellasthemanyactivitiesthathavebeencarriedoutsincede.NBIestablishment.AnEnglishversionisintended.

www.denbi.de

VON DER DATENANALYSE ZUM VERSTEHEN KOMPLEXERBIOLOGISCHER SYSTEME Highlights aus dem Deutschen Netzwerk für Bioinformatik-Infrastruktur

www.denbi.de

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Forfurtherdetails,pleaserefertothefullversionat:https://www.denbi.de/images/Downloads/deNBI_highlight_brochure_Ger-man.pdf

Fortheprintedversionpleasecontactthede.NBIofficeat:[email protected]

ELIXIRGERMANYCOLLABORATIONAGREEMENTSIGNED

On9January2020,theNationalCollaborationAgreementtoestablishtheGermanELIXIRNode(ELIXIR-DE) became effective. This contract was signed by 21 German universities and re-searchinstitutes,includingBielefeldUniversitythatwilltakeoverthelegalroleas‘Represent-ing Entity‘ of ELIXIR Germany. TheNationalCollaboration Agreement is the legal documentthat specifies the organization of ELIXIR-DE and the role of the Central Coordination Unit(CCU).Thiscommitteeisthedecision-makingbodyofELIXIR-DEandresponsiblefortheeffec-

tiveoperationofthenationalELIXIRnode.TheCCUconsistsofninemembers,includingtheHeadofNodeandrepresent-ativesoftheeightserviceunitsofELIXIR-DE.

Inaddition,theELIXIRCollaborationAgreementwassignedbytheRepresentingEntityandtheELIXIRDirector,NiklasBlomberg.Thiscontractbecameeffectiveon10February2020,therebyfullyestablishingtheGermanELIXIRNode.TheELIXIRCollaborationAgreement is the legaldocument that tiestogether theELIXIRHubwith thenationalnodeand itformsthelegalbasisofCommissionedServices.ThesetechnicalprojectsthatguidefutureservicedevelopmentsarefundedthroughthebudgetoftheELIXIRHubandareimplementedbyELIXIRmembersinthenationalnodes.

BJÖRNGRÜNING(RBC)APPOINTEDASLEADOFTHEELIXIRTOOLSPLATFORMInDecember2019ELIXIRannouncednewPlatformLeadsfortheTools,DataandTrainingPlatforms.BjörnGrüning(RBCFreiburg/ELIXIRGermany)wasappointedasPlatformLeadof theELIXIRToolsPlatforms togetherwithSalvadorCapella(ELIXIRSpain)andHervéMenager(ELIXIRFrance).ThePlatformLeadswillserveatwo-yeartermstartingfromthe1January2020.TheyarecollectivelyresponsiblefortheoperationsandactivitiesofthePlatform,andhelptodrivenewdevelopmentsintherespectivetaskareas.ThemainobjectiveoftheELIXIRToolsPlatformistoimprovethediscovery,qualityandsustain-abilityofsoftwareresources.BjörnGrüningisalsoCo-LeaderoftheGalaxyWorkingGroupoftheToolsPlatform,togetherwithFrederikCoppens(ELIXIRBelgium).ThegoalofthisworkinggroupistocontributetothedevelopmentoftheGalaxyplatformandtoprovidespecifictrainingforusers,developersandsystemadministrators.

Moreinformation:https://elixir-europe.org/news/elixir-welcomes-six-new-platform-leads

JOHANNESWERNER(IOW)ASSOCIATEDasde.NBITRAININGPARTNERTheCentralCoordinationUnitofde.NBIapprovedtheapplicationbyJohannesWernertobecomeassociatedtothenetworkas anexternal trainingpartner. Since2018, Jo-hannesWerner is bioinformatics scientist inmarinemicrobialbioinformatics at theDepartmentofBiologicalOceanographyoftheLeibnizInstituteforBalticSeaResearch(IOW)inRostock-Warnemünde.Hisresearchfocusdealsmainlywiththemeta-omicsanalysesofmi-crobialcommunitiesincontactwithanthropogenoussubstances.JohannesWerneralsoconductstrain-ing inbioinformaticsonaregularbasis.Hewillcontributetothede.NBItrainingprogrambyofferingadvancedtraining courseson16SrRNAampliconanalysiswith theRpackagesDADA2 (https://ben-jjneb.github.io/dada2/index.html)andphyloseq(http://joey711.github.io/phyloseq/

STEPHANFUCHS(RKI)AFFILIATEDASASSOCIATEDde.NBIPARTNERIn January 2020, theCentralCoordination Unit (CCU) of de.NBI unanimously approved the applicationof Dr. StephanFuchstobecomeanAssociatedPartnerofthede.NBIconsortium.StephanFuchsisresearcherattheRobertKochInstitute(RKIWernigerode).TheRKI isthegovernment’scentralscientific institutioninthefieldofbiomedicineandoneofthemostimportantbodiesforthesafeguardingofpublichealthinGermany.

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StephanFuchsgainedscientificexperienceinthefieldsofmulti-andmeta-Omicsanalyseswithastrongfocus onnosocomial infections and antibiotic resistances. In the fieldofMetaproteomics, he alreadycollaboratedwith thede.NBIpartnerproject ‚MetaProtServ‘ofDirkBenndorf andGunterSaakefromOttovonGuerickeUniversityMagdeburg.TogetherwiththeMagdeburgteamStephanFuchswillcon-tributetode.NBIservicesandtrainingcourses inmetaproteomeanalysiswiththeMetaProteomeAna-lyzer (MPA) Software (http://www.mpa.ovgu.de) and a de.NBICloud-based versionof theProphaneanalysissoftware(http://www.prophane.de).

THEde.NBIINTHECONTEXTOFARTIFICIALINTELLIGENCEDuring the last session of theCentralCoordination Unit (CCU)on 21 January 2020 in Bielefeld, apaperwith the title„de.NBIimKontextvonMethodenderKünstlichenIntelligenz“,writtenbytheSpecialInterestGrouponde.NBIde-velopment,wasdiscussedandfinallyaccepted.

Thekeyinformationofthisdocumentis:• Deeplearningandartificialintelligencerequirelargeamountsofdata,bioinformaticstoolsandapplicationdomain

expertstoachievebreakthroughsinthelifesciences.• Thede.NBInetwork,asaninfrastructurewheredatafrommanysourcesareprocessedandsubject-specificexpertise

is gathered, canmake decisive contributions to enable artificial intelligence in the life sciences in Germany at aninternationallycompetitivelevel.

Further,itshouldbementionedthatthreePIfromthede.NBInetworkwereselectedbytheFederalMinistryforEducationandResearch(BMBF)tocarryoutresearchprojectsintheframeoftheinitiative„ComputationalLifeSciences(CompLS)-DeepLearninginderBiomedizin“.Thetitlesoftheseresearchprojectsdealwith(a)Deeplearningforthedetectionofproteinvariants, (b) Development of a tool to support the curation of text and bio data and (c) Identificationofnewantimicrobialresistancetargets.

TheGermantextofthiswhitepaperisavailablevia:https://www.denbi.de/images/Downloads/deNBI_KI.pdf.

GUIDELINESFORde.NBISERVICESADOPTEDThede.NBInetworkhassuccessfullyestablishedguidelinesforNodeserviceselectionandqualityassuranceforservicesofferedtothelifescienceresearchcommunitywithinGermanyandEurope.

TheGuidelinesdescribea listofrequiredimplementationsforthe continuationofa certain servicewithin thede.NBIserviceportfolio.Theprocedureissettofacilitatethemonitoringandconstantevaluationoftheexistingservices,aswellashelp intheprocessofendorsingnewonesofferedbyexternalserviceproviders.Withsuchaprocedureinplace, thede.NBInetworkcanguaranteetherelevanceandmaximumperformanceofitsservicesaccordingtothehighestscientificstandards.

Thequalityassurance criteria forde.NBI services are inclusiveandensure thattheoffered services shouldfulfill highscientificandtechnicalstandardsandcomplywithethicalandprivacylegalitiesregardingdataprotectionaswellastheopenscienceandFAIRdataprinciple.Thedocumentwasunanimouslyapprovedbythede.NBICentralCoordinationUnit(CCU)ontheirmeetingonthe22ndofOctober,2019inBielefeld.Thede.NBIadministrationofficestaffwillrunperiodicchecksontheexistingde.NBIservices

Workflow and visualization of results in Prophane

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basedontheapprovedqualityassurancecriteriainordertomaintaintheirperformanceatthehighestcapacity.

Formoredetailspleaserefertothefulltextunderhttps://www.denbi.de/images/Service/deNBI_ELIXIR-DE_Gudielines_Ser-vices.pdf

NEWRECORD:1,586TRAININGCOURSEPARTICIPANTSIN2019Thefifthde.NBIyearwasverysuccessfulinthefield 'training'. In2015,de.NBI startedwith17training coursesand329participants,with in-creasingnumbersin2016(40courseswith882participants),2017(69courseswith1,489par-ticipants)and2018(77courseswith1,520).Inthelastyear,de.NBIfurtherincreasedthenum-ber of courses and participants: 79 trainingcourses with 1,586 participants. The largestcoursewasattendedby72,thesmallestonebyfourscientists.Approx.75%oftheparticipantswerePhDstudentsorPostdocs.Theremaining25%werePIs,undergraduates,andparticipantsfromindustry.Thegenderratioofthestudentswas56%maleand44%female.About30%oftheparticipantscamefromoutsideGermany.Ingeneral,theusersurveyshowssatisfactionvaluesaround90%.Morethan60trainingcourseswithalargevarietyofscientifictopicsarealreadyannouncedfor2020.

UseGalaxy.euPROVIDESHUMANMULTI-OMICSDATAFROMUKPERSONALGENOMEPROJECT

TheFreiburgGalaxyTeamheadedbyBjörnGrüning(RBCFreiburg)announcedthatso-calledmulti-omics reference panel data from the Personal Genome Project UK(PGP-UK) isnowaccessibledirectlyonGalaxyEurope.Thisincludesunprocesseddata,

butalsopregeneratedresults,fromthe10participantswithcompletemulti-omicsdata(whole-genome,methylomeandtranscriptome). InterestedusersofGalaxyEuropeareencouraged touse thedatafor establishingnewworkflows, forowntrainingcoursesandtohonetheirowndataanalysisskills. TheGalaxyTrainingNetworkprovideshands-ontutorialstogetyoustartedwiththeanalysisofthiskindofdata.

MoreInformation:https://galaxyproject.eu/posts/2020/01/16/pgp/

INITIALANALYSISOFCOVID-19DATAUSINGGALAXY,BIO-CONDAANDPUBLICRESEARCHINFRASTRUCTURE(XSEDE,de.NBI-CLOUD,ARDCCLOUD)TheGalaxydevelopmentteamsfromgalaxy.org,galaxy.eu,galaxy.be,andgalaxyorg.auhaveprovidedthepublicreposi-torieswithdescriptionsofallworkflowsandsoftwareversionsusedfortheinitialanalysisofCOVID-19datausingGalaxy,BioCondaandpublicresearchinfrastructure(XSEDE,de.NBI-cloud,ARDCcloud).Thisworkwasaccomplishedwithcon-siderableinvolvementofstafffromRBCFreiburg.

Abstractofthepublication:ThecurrentstateofmuchoftheWuhanpneumoniavirus(COVID-19)researchshowsaregrettablelackofdatasharingandconsiderableanalyticalobfuscation.Thisimpedesglobalresearchcooperation,whichisessentialfortacklingpublichealthemergencies, andrequiresunimpededaccess todata, analysis tools, and computational infrastructure.Hereweshowthatcommunityeffortsindevelopingopenanalyticalsoftwaretoolsoverthepasttenyears,combinedwithnationalinvestmentsintoscientificcomputationalinfrastructure,canovercomethesedeficienciesandprovideanaccessibleplat-formfortacklingglobalhealthemergenciesinanopenandtransparentmanner.Specifically,weuseallCOVID-19genomicdataavailableinthepublicdomainsofarto(1)underscoretheimportanceofaccesstorawdataandto(2)demonstrate

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thatexistingcommunityeffortsincurationanddeploymentofbiomedicalsoftwarecanreliablysupportrapid,reproduc-ibleresearchduringglobalhealthcrises.

Allanalysesarefullydocumentedat:https://github.com/galaxyproject/SARS-CoV-2.

Linktotheoriginalpublication:https://doi.org/10.1101/2020.02.21.959973

NEWSFROMTHEde.NBIOFFICE RabeaaAlkhateebwillleavethede.NBIAdministrationOfficebyendofFebruary2020afteralmosttwoyearsofworkingasthede.NBIServiceCoordinatorandELIXIRGermanyNodeCoordinator.Rab-eaawillmoveonwithhercareerworkingasapostdoctoralresearcherinthefieldofsinglecelltran-scriptomicsandgenomics.WehaveenjoyedhavingRabeaaasamemberofourteamandwouldliketowishherallthebestforthenextsteps!

RECENTUPDATESOFde.NBISERVICESNewversionsofvariousde.NBIservicesandtoolshavebeenreleasedinthelastmonthsaccompaniedbyrespectivepublications:

SILVAngsFrontendupdatedtoversion1.9.5.Newfeaturesinclude:updatedFingerprintTool,updatedinformationand the de.NBI cloud and improved stability and performance. https://www.denbi.de/services/344-silvangs-a-data-analysis-service-for-ribosomal-rna-gene-rdna-amplicon-reads-from-high-throughput-sequencing-next-gene-ration-sequencing-ngs-approaches

OpenMS:ThenewalgorithmsFLASHDecon,availablethroughOpenMSprovides2-3ordersofmagnitudefasterdeconvolutionoftop-downproteinspectraPublication:FLASHDeconv:Ultrafast,High-QualityFeatureDeconvolutionfor Top-Down Proteomics. https://doi.org/10.1016/j.cels.2020.01.003 Find OpenMS at:https://www.denbi.de/services/369-openms-a-c-library-for-lc-ms-data-management-and-analyses

Mercator:Theannotationtool forplatproteinsoffersnow integratedFASTA functional annotationforplantproteins.https://www.denbi.de/services/507-mercator-annotate-and-classify-plant-protein-and-dna-sequences

SeqAN3.0.1:Anewreleasehasbeenpublished. Seethenewfeaturesat: http://www.seqan.de/seqan-3-0-1-released/

Siamcat:Newpublicationisout:SIAMCAT:user-friendlyandversatilemachine learningworkflowsforstatisti-cally rigorousmicrobiomeanalyses, J.Wirbel,K. Zych,M.Essex,N.Karcher, E.Kartal,G. Salazar,P. Bork,S.Suna-gawa,G. Zeller; doi:https://doi.org/10.1101/2020.02.06.931808 . Find the service at:https://www.denbi.de/services/272-siamcat-modular-framework-for-the-statistical-inference-of-associa-tions-between-microbial-communities-and-host-phenotypes

FreiburgRNAToolsWebserver:NewintegrationofMutaRNAtooltoevaluatemutationeffectsonRNAstruc-tureandanupdatedIntaRNA3.1.3forRNA-RNAinteractionprediction.https://www.denbi.de/services/356-freiburg-rna-tools-webserver

UseGalaxy.eu published a factsheet available at: https://github.com/usegalaxy-eu/branding/tree/mas-ter/factsheet.Exciting progress in the ELIXIRGalaxy community is described in the newspost https://elixir-europe.org/news/galaxy-europe-2020

CropAnalysisToolsSuite(CATS):ThetoolKmaskerplantsbit.ly/2G738pdhasbeenupdated.Itallowstheiden-tification of repetitive sequences and thus facilitates the analysis of plant genomes. Find CATS athttps://www.denbi.de/services/503-crop-analyis-tools-suite

de.NBI@CONFERENCES

de.NBIsupportedconferencesinthenearfuture 6thjointconferenceofDGHMandVAAM,8-11Mar2020,Leipzig

de.NBIwillexhibitaboothatthelargestGermanconferenceinthesectormicrobiol-ogyandhygiene.Anexpectedaudienceof>1000scientistswillprovidetheoppor-tunitytointroducede.NBIservices,trainingportfolio,andcloudtoalargecommunity.

Generalinformationandregistrationat:https://vaam.de/aktivi-taeten/jahrestagung/

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UPCOMINGEVENTSThecalendarliststhede.NBItrainingcoursesandeventsscheduledinthenextmonths.Allcoursesareaccessibleviathede.NBIwebpage.Anumberoftrainingeventsareinthepipelinebutnotyetscheduled.Pleaseconsultthede.NBItrainingprogramforupdates.

Overviewofupcomingde.NBIevents

Date Event City Organizer

26Feb2020 BioC++-solvingdailybioinformatictaskswithC++efficiently-BIOSTEC2020 Valletta CIBI

02-06Mar2020 GalaxyAdminworkshop2020 Barcelona RBC

05Mar2020 IntroductiontoDataManagement Plön de.NBI-SysBio

15-21Mar2020 OpenMSDeveloperMeeting Corinth CIBI

18Mar2020 IntroductiontoRegularExpressions Heidelberg HD-HuB

23-27Mar2020 GalaxysinglecellRNA-seqdataanalysisworkshop Freiburg RBC

30-31Mar2020 SoftwareCarpentry1.2020 Köln Ass. Partner ZB MED

30Mar–01Apr

2020 IntroductiontoMachineLearningusingGalaxy Freiburg RBC

03Apr2020 KNIMEWorkshopatSpringSummit Berlin CIBI

21April2020 22.CCUMeeting Berlin CAU/HD-HuB

27-29Apr2020ToolsforSystemsbiologymodelinganddataexchange:CO-PASI,CellNetAnalyzer,SABIO-RK,FAIRDOMHub/SEEK2020 Magdeburg de.NBI-SysBio

04-06May2020 6thde.NBIGenomicstrainingcourse Gießen BiGi et al.

18-19May2020 DNAMethylation:DesigntoDiscovery2020 Saarbrücken HD-HuB/ de.NBI-epi

20May2020 Phylogeneticreconstructioncourse2020 Kiel Ass. Partner Kiel

15-17Jun2020Computationalgenomicscourseforhands-ondataanalysis2020-Modules:Datavisualization&machinelearning,RNASeq,SingleCellSeq

Berlin RBC/de.NBI-epi

21-26Jun2020 CSAMA2020:StatisticalDataAnalysisforGenome-ScaleBiol-ogy

Bressanone-Brixen HD-HuB

30Jun2020 23.CCUMeeting Bochum CAU/BioIn-fra.Prot

24-28Aug2020 CICSummerSchoolonCheminformatics Halle(Saale) BioData

14Sep2020 OpenMSattheGermanConferenceforBioinformatics(GCB) Frankfurt CIBI

14Sep2020 SeqAnattheGermanConferenceforBioinformatics(GCB) Frankfurt CIBI

14Sep2020 ProteinsPlusattheGermanConferenceforBioinformatics(GCB) Frankfurt BioData

21-25Sep2020 de.NBISummerSchool2020-Metagenomics Gießen BiGi,

11Oct2020 COMBINE&de.NBITutorial:ModellingandSimulationToolsinSystemsBiology–ICSB2020 Farmington de.NBI-SysBio

Furtherinformationat:http://www.denbi.de/training

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IMPRESSUM RESPONSIBLEFORCONTENTSA.Pühler,A.Tauch,T.Dammann-Kalinowskide.NBI-GermanNetworkforBioinformaticsInfrastructurec/oCenterforBiotechnology(CeBiTec)BielefeldUniversity33594BielefeldGermanyPhone:+49-(0)521-106-8750Fax:+49-(0)521-106-89046email:[email protected]:https://www.denbi.deemail:[email protected]:#denbi,@denbiOfficelinkedIn:https://www.linkedin.com/company/de-nbiForquestionsandremarkspleasecontactcontact@denbi.deThede.NBIissupportedbyBMBFgrantsFKZ031A532-031A540and031L0101-031L0108.

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