pulmonary vein isolation vs. ablate and pace … · pulmonary vein isolation vs. ablate and pace...
TRANSCRIPT
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PULMONARY VEIN ISOLATION
VS. ABLATE AND PACE FOR
ATRIAL FIBRILLATION:
PVI IT IS
GIRISH M NAIR MBBS, MSC, FRCPC, FHRS
ASSOCIATE PROFESSOR
ARRHYTHMIA SERVICE
DIVISION OF CARDIOLOGY, UNIVERSITY OF OTTAWA HEART INSTITUTE
OTTAWA, ON CANADA
IWAS 08022015
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Disclosures
• Honoraria and research grants from St.
Jude Medical and Medtronic Inc.
• I perform both PVI and AV node ablation
with pacemaker implantation
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Outline/Objectives
• Make a case for Pulmonary vein isolation
as first line treatment for paroxysmal,
symptomatic AF
• Convince the audience and my good
friend Dr. Jeff Healey that AV node
ablation and pacing should be used as a
last resort for the management of
paroxysmal, symptomatic AF
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AF is Heterogeneous
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Paroxysmal AF Affects Younger Subjects
Chugh et.al. J Am Coll Cardiol. 2001;37 (2):371-378
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High Burden Symptomatic AF
Burden on Health Care
Reynolds MR et.al. J Cardiovasc Electrophysiol.
2007;18:628-633.
•Patients with AF who are managed with cardioversion and pharmacotherapy incur AF- and
cardiovascular-related healthcare costs of $4,000-5,000 per year.
•Hospital care makes up the largest and most variable component of overall costs
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Symptomatic Subjects Need Rhythm
Control
Nieuwlaat R et.al. European Heart Journal. 2005;26:2472-
2434
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Dr. Healey is Going to Tell You...!
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Dr Healey is Also Going to Show You
Results From - MANTRA
The Ablators did not use Pulmonary Vein
Isolation as an endpoint for ablation and
used non-irrigated catheters for ablation.
Almost a sham procedure!
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Then Dr. Healey Conducted
The RAAFT Trial
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AV Node Ablation Last Resort
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2014 Focused Update of the Canadian Cardiovascular Society Guidelines for the
Management of Atrial Fibrillation. Can J Cardiol. 2014 ; 30: 1114-1130
J.S. HEALEY- AUTHOR!
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HRS/ACC Guidelines
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A Typical Healey Patient!
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CONCLUSIONS
• The TREATMENT OF CHOICE for symptomatic subjects
with Paroxysmal AF, especially those who have failed an
antiarrhythmic medication (Class I/III), is CATHETER
ABLATION
• The aim is to reduce AF burden and symptoms and not
cure AF
• Subjects will need two or more procedures (10-20%) and
have to accept a small risk of serious complications
• I sincerely hope Dr. Healey practices what he preaches
and doesn’t put his patients on Amiodarone or burn their
AV nodes!
Cardiac Electrophysiology: Cell to Bedside: Zipes D et al.
Fogoros RN. Blackwell Futura: Antiarrhythmic Drugs- A Practical Guide
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THANK YOU